Wyniki wyszukiwania dla: DRUG RESEARCH

• Current drug abuse reviews

  Czasopisma

  ISSN: 1874-4737

• Infectious Disorders - Drug Targets

  Czasopisma

  ISSN: 1871-5265

• Journal of Nanopharmaceutics and Drug Delivery

  Czasopisma

  ISSN: 2167-9312

• Drug Discovery Today: Technologies

  Czasopisma

  ISSN: 1740-6749

• Therapeutic Advances in Drug Safety

  Czasopisma

  ISSN: 2042-0986 , eISSN: 2042-0994

• Adverse Drug Reaction Bulletin

  Czasopisma

  ISSN: 0044-6394

• Current Drug Discovery Technologies

  Czasopisma

  ISSN: 1570-1638

• Drug Safety - Case Reports

  Czasopisma

  ISSN: 2199-1162

• Journal of Alcohol and Drug Education

  Czasopisma

  ISSN: 0090-1482

• Drug Metabolism and Personalized Therapy

  Czasopisma

  ISSN: 2363-8907

• Adverse Drug Reactions Journal

  Czasopisma

  ISSN: 1008-5734

• Cancer Drug Discovery and Development

  Czasopisma

  ISSN: 2196-9906 , eISSN: 2196-9914

• NATURE REVIEWS DRUG DISCOVERY

  Czasopisma

  ISSN: 1474-1776 , eISSN: 1474-1784

• Dr.shazia Farheen Qureshi

  Osoby

  I am Psychiatrist wants to heal and inspire the minds. I did post grdauation from College of Physicians and Surgeons of Bombay, Mumbai, India. I am having 10 years experience in field of Psychiatry in variety of Clinical settings that have included Child, Adolesecent, Geriatric and Forensic Psychiatry and drug deaddiction services also clinical research work.

• Development of a Peptide Derived from Platelet-Derived Growth Factor (PDGF-BB) into a Potential Drug Candidate for the Treatment of Wounds

  Publikacja

  • M. Deptuła
  • P. Karpowicz
  • A. Wardowska
  • P. Sass
  • P. Sosnowski
  • A. Mieczkowska
  • N. Filipowicz
  • M. Dzierżyńska
  • J. Sawicka
  • E. Nowicka... i 14 innych

  - Advances in Wound Care - Rok 2020

  Objective: This study evaluated the use of novel peptides derived from platelet-derived growth factor (PDGF-BB) as potential wound healing stimulants. One of the compounds (named PDGF2) was subjected for further research after cytotoxicity and proliferation assays on human skin cells. Further investigation included evaluation of: migration and chemotaxis of skin cells, immunological and allergic safety, the transcriptional analyses...

  Pełny tekst do pobrania w serwisie zewnętrznym

• Fabrication methods of smart composite coatings - review

  Publikacja

  • Ł. Pawłowski
  • M. Bartmański
  • A. Zieliński

  - European Journal of Medical Technologies - Rok 2019

  Postoperative bacterial infections are one of the main reasons for unsuccessful implantation of long-term implants. The development of bacterial infection requires antibiotic therapy, in extreme cases a reimplantation procedure is necessary. In order to provide materials for implants with antibacterial properties, they are subjected to modifications to create a coating that will release the drug substance, when the inflammation...

  Pełny tekst do pobrania w portalu

• Synthesis of disubstituted 1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids derivatives

  Publikacja

  • A. S. Skwarecki

  - Rok 2013

  1,3,4,9-tetrahydropyrano[3,4-b ]indole-1-acetic acid derivatives are of interest for pharmaceutical research as a core structure for synthesis of biological active substance - Etodolac (selective Cyclooxygenase-2 inhibitor, which belongs to the Non-steroidal Anti-inflammatory Drug, NSAID, that shows a clin-ically effective analgesic and anti-inflammatory activity). Here the way of synthesis of two 1,3,4,9-tetrahydropyrano[3,4-b...

  Pełny tekst do pobrania w serwisie zewnętrznym

• Drug-Eluting Biopsy Needle as a Novel Strategy for Antimicrobial Prophylaxis in Transrectal Prostate Biopsy

  Publikacja

  • M. Sieczkowski
  • A. Gibas
  • A. Wasik
  • A. Kot-Wasik
  • L. Piechowicz
  • J. Namieśnik
  • M. Matuszewski

  - TECHNOLOGY IN CANCER RESEARCH & TREATMENT - Rok 2017

  OBJECTIVES: To preclinically evaluate drug-eluting biopsy needles (patent pending WO2016118026) as a new potential way of antimicrobial prophylaxis for transrectal prostate biopsy. METHODS: Twenty steel biopsy needles have been coated with polyvinyl alcohol, ciprofloxacin, and amikacin. Modified biopsy needles have been randomly divided into 3 groups (1:2:1 ratio). Needles from group I were immersed for 30 minutes in dedicated...

  Pełny tekst do pobrania w portalu

• Antibacterial Porous Systems Based on Polylactide Loaded with Amikacin

  Publikacja

  • M. Glinka
  • K. Filatova
  • J. Kucińska-Lipka
  • T. Šopík
  • E. Domincová Bergerová
  • V. Mikulcová
  • A. Wasik
  • V. Sedlařík

  - MOLECULES - Rok 2022

  Three porous matrices based on poly(lactic acid) are proposed herein for the controlled release of amikacin. The materials were fabricated by the method of spraying a surface liquid. Description is given as to the possibility of employing a modifier, such as a silica nanocarrier, for prolonging the release of amikacin, in addition to using chitosan to improve the properties of the materials, e.g., stability and sorption capacity....

  Pełny tekst do pobrania w portalu

• Utilizing Morphological and Physiological Parameters of Lemna minor for Assessing Tetracyclines’ Removal

  Publikacja

  • Ł. Sikorski
  • A. Bęś
  • K. Warmiński
  • W. Truszkowski
  • P. Kowal

  - MOLECULES - Rok 2024

  Antibiotics with significant environmental toxicity, e.g., tetracyclines (TCs), are often used in large quantities worldwide, with 50–80% of the applied dose ending up in the environment. This study aimed to investigate the effects of exposure to tetracycline hydrochloride (TC) and minocycline hydrochloride (MIN) on L. minor. Our research evaluated the phytotoxicity of the TCs by analyzing plant growth and biomass and evaluating...

  Pełny tekst do pobrania w serwisie zewnętrznym

• REVIEW OF CURRENT RESEARCH ON CHITOSAN AS A RAW MATERIAL IN THREE-DIMENSIONAL PRINTING TECHNOLOGY IN BIOMEDICAL APPLICATIONS

  Publikacja

  • S. Mania
  • A. Banach-Kopeć
  • R. Tylingo

  - Progress on Chemistry and Application of Chitin and Its Derivatives - Rok 2020

  Three-dimensional (3D) biomaterial manufacturing strategies show an extraordinary driving force for the development of innovative solutions in the biomedical sector, including drug delivery systems, disease modelling and tissue and organ engineering. Due to its remarkable and promising biological and structural properties, chitosan has been widely studied for decades in several potential applications in the biomedical field. However,...

  Pełny tekst do pobrania w portalu

• Recent breakthroughs in the stability testing of pharmaceutical compounds

  Publikacja

  • M. Jamrógiewicz
  • K. Pieńkowska

  - TRAC-TRENDS IN ANALYTICAL CHEMISTRY - Rok 2019

  Pharmaceutical development is mostly focused on the research leading to approval of a new and viable active substance. However, there is a number of old generation compounds that are still being used in contemporary medicinal practice. So that new analytical developments should cover not only the safety of newly developed drug substances, which is obvious, but should also be directed into the search of individual stability issues...

• In silico design of telomerase inhibitors.

  Publikacja

  • M. Bagiński
  • K. Serbakowska

  - DRUG DISCOVERY TODAY - Rok 2020

  Telomerase is a reverse transcriptase enzyme involved in DNA synthesis at the end of linear chromosomes. Unlike in most other cells, telomerase is reactivated most cancerous cells and, therefore, has become a promising new anticancer target. Despite extensive research, direct telomerase inhibitors have yet not been introduced to the clinics because of the complexity of this enzyme. Structures of this protein from simple organisms...

  Pełny tekst do pobrania w portalu

• The Metal-Free Regioselective Deuteration of 2-Methylquinolin-8-ol and 2,5-Dimethylquinolin-8-ol, Spectroscopic and Computational Studies

  Publikacja

  • J. Nycz

  - Current Green Chemistry - Rok 2022

  Abstract: Aim and Background: Introducing deuterium to a molecule is of interest to a wide variety of research, including investigation of reaction mechanisms or kinetics, analysis of drug metabolism, structural elucidation of molecules, and syntheses of isotopically labeled materials used for NMR spectroscopy and medicinal research. Objective: The transition-metal-free regioselective deuteration of 2-methylquinolin-8-ol...

• CURRENT CANCER DRUG TARGETS

  Czasopisma

  ISSN: 1568-0096 , eISSN: 1873-5576

• Letters in Drug Design & Discovery

  Czasopisma

  ISSN: 1570-1808 , eISSN: 1875-628X

• CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT

  Czasopisma

  ISSN: 1367-6733

• EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

  Czasopisma

  ISSN: 0378-7966 , eISSN: 2107-0180

• ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT

  Czasopisma

  ISSN: 1087-2906

• Expert Opinion on Drug Metabolism & Toxicology

  Czasopisma

  ISSN: 1742-5255 , eISSN: 1744-7607

• Journal of Global Drug Policy and Practice

  Czasopisma

  ISSN: 1934-4708

• African Journal of Drug and Alcohol Studies

  Czasopisma

  ISSN: 1531-4065

• Recent Patents on CNS Drug Discovery

  Czasopisma

  ISSN: 1574-8898

• Drug Discovery Today: Disease Models

  Czasopisma

  ISSN: 1740-6757

• Indian Journal of Novel Drug Delivery

  Czasopisma

  ISSN: 0975-5500

• Recent Patents on Drug Delivery and Formulation

  Czasopisma

  ISSN: 1872-2113

• Cardiovascular and Hematological Disorders - Drug Targets

  Czasopisma

  ISSN: 1871-529X

• International Journal of Drug Delivery Technology

  Czasopisma

  ISSN: 0975-4415

• JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

  Czasopisma

  ISSN: 1773-2247

• Recent Advances in Drug Delivery and Formulation

  Czasopisma

  ISSN: 2667-3878 , eISSN: 2667-3886

• AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE

  Czasopisma

  ISSN: 0095-2990 , eISSN: 1097-9891

• CURRENT DRUG METABOLISM

  Czasopisma

  ISSN: 1389-2002 , eISSN: 1875-5453

• Investigating the disease- modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition

  Publikacja

  • A. Ayyolath
  • A. Kallingal
  • V. Thachan Kundil
  • A. Maniyeri Suresh
  • J. V. E.

  - Chemical Biology & Drug Design - Rok 2023

  Alzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day-to-day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability....

  Pełny tekst do pobrania w serwisie zewnętrznym

• Results of modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models using Aliivibrio fischeri bacterium as model organism

  Dane Badawcze

  open access

  • M. Wieczerzak
  • B. Kudłak

  The research was concerned with verifying the impact of mixtures of nine pharmaceuticals against a selected organism, i.e., the bacterium Aliivibrio fischeri. A. fisheri is used as a model organism in the monitoring of acute toxicity in environmental and reference samples in Microtox® systems.  Tested pharmaceuticals, namely: diclofenac (sodium salt),...

• Electrochemistry meets enzymes: Investigation of the biotransformation pathway of C-1311 based on electrochemical simulation in comparison to in vitro methods.

  Publikacja

  • A. Potęga

  - Journal 0f Clinical Toxicolgy - Rok 2014

  The knowledge of the metabolic pathways and the biotransformation of new drugs is one of the major challenges in pharmaceutical research. It is crucial for elucidation of degradation routes of the new biologically active compounds, especially in the area of possible toxicity. Conventional in vitro drug metabolism studies are based on incubating drug candidate with e.g. hepatocytes or, most importantly, liver cell microsomes and...

• Degradation of cefadroxil drug by newly designed solar light responsive alcoholic template-based lanthanum ferrite nanoparticles

  Publikacja

  • A. Nazir
  • M. Imran
  • F. Kanwal
  • S. Latif
  • A. Javaid
  • T. H. Kim
  • G. Boczkaj
  • A. Shami
  • H. M. Iqbal

  - ENVIRONMENTAL RESEARCH - Rok 2023

  In this work, lanthanum ferrite nanoparticles were synthesized via a simple co-precipitation method. Two different templates, namely sorbitol and mannitol, were used in this synthesis to tune the optical, structural, morphological, and photocatalytic properties of lanthanum ferrite. The synthesized lanthanum ferrite-sorbitol (LFOCo-So) and lanthanum ferrite-mannitol (LFOCo-Mo) were investigated through Ultraviolet–Visible (UV–Vis),...

  Pełny tekst do pobrania w serwisie zewnętrznym

• 2D MXene nanocomposites: electrochemical and biomedical applications

  Publikacja

  • M. Ramezani Farani
  • B. Nourmohammadi Khiarak
  • R. Tao
  • Z. Wang
  • S. Ahmadi
  • M. Hassanpour
  • M. Rabiee
  • M. Saeb
  • E. C. Lima
  • N. Rabiee

  - Environmental Science-Nano - Rok 2022

  In recent years, key questions about the interaction of 2D MXene nanomaterials in electrochemical and biomedical applications have been raised. Most research has focused on clarifying the exclusive properties of the materials; however, only limited reports have described the biomedical applications of 2D nanomaterials. 2D MXenes are monolayer atomic nanosheets resulting from MAX phase ceramics. The hydrophilic properties, metallic...

  Pełny tekst do pobrania w serwisie zewnętrznym

• CRITICAL REVIEWS IN THERAPEUTIC DRUG CARRIER SYSTEMS

  Czasopisma

  ISSN: 0743-4863 , eISSN: 2162-660X

• International Journal for Parasitology-Drugs and Drug Resistance

  Czasopisma

  ISSN: 2211-3207

• Endocrine Metabolic & Immune Disorders-Drug Targets

  Czasopisma

  ISSN: 1871-5303 , eISSN: 2212-3873