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The effect of valley depth on areal form removal in surface topography measurements
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Renal Regulation of Calcium-Phosphate Metabolism in Single- and Twin Pregnant Goats
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TOLLIP Protein Expression Predicts Unfavorable Outcome in Renal Cell Carcinoma
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Cathepsin C is a novel mediator of podocyte and renal injury induced by hyperglycemia
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Effect of renal replacement therapy on selected arachidonic acid derivatives concentration
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Rationale and design of a large registry on renal denervation: the Global SYMPLICITY registry
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Conservative Treatment of Didelphyc Uterus with Obstructed Hemivagina and Ipsilateral Renal Agenesis
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Acute renal failure due to leptospirosis. Diagnostic challenges – a case report
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Stadion PGE Arena Gdańsk - niezawodność zasilania i ochrona przeciwporażeniowa
PublikacjaW artykule przedstawiono problematykę zasilania stadionu piłkarskiego PGE Arena Gdańsk. Zwrócono uwagę na układ zasilania obiektu z punktu widzenia niezawodności dostawy energii elektrycznej wymaganej w szczególności podczas międzynarodowych imprez sportowych rangi mistrzowskiej. Omówiono przyjęte rozwiązania ochrony przeciwporażeniowej w urządzeniach wysokiego i niskiego napięcia.
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Comprehensive Metabolic Signature of Renal Dysplasia in Children. A Multiplatform Metabolomics Concept
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Stadion PGE Arena – dobre praktyki zarządzania projektem budowlano-infrastrukturalnym
PublikacjaW opracowaniu zaprezentowano case study, tj. opis przebiegu projektu, którego celem było wybudowanie stadionu piłkarskiego w Gdańsku. Inicjatywa budowy stadiony była związana ze zgłoszeniem Gdańska, jako miasta-gospodarza mi-strzostw Euro 2012. Główne działania zrealizowane w projekcie, tj. od inicjacji projektu aż do oddania obiektu do użytkowania zostały zestawione chronolo-gicznie w skali czasu. Wyeksponowano również szereg...
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TOPOLOGICAL CLUES FOR PREDICTING OUTCOMES OF MULTIPLAYER ONLINE BATTLE ARENA GAMES
PublikacjaWith 27 million people playing League of Legends every day, e-sports became more and more important part of our everyday life. Rise of its popularity builds a demand for better understanding e-sports mechanics on a deeper level. In the article, we test a hypothesis that it is possible to predict an outcome of Multiplayer Online Battle Arena game based on topological clues only (such as area of polygon where vertices are players...
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Roof over PGE Arena in Gdansk. Review of structure and monitoring system
PublikacjaThis paper presents general structural assumptions of the steel construction designed for a newfootball stadium to be built for UEFA Championship 2012 in the city of Gdańsk. The superstructureis founded directly on the modified abutment. The facade and the roof are collected from 82 steelgirders made of tube profiles. The girders are braced by circular beams and X tension rods. All thiscreates a quasi - dome covered by polycarbonate...
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Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer
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Determination of oxygen saturation and photosensitizer accumulation in the tumor with the help of LEDand laser diode-based irradiation sources and fiber-optics probes
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Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients
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Do not die, become senescent: a new type of cellular resistance induced by topoisomerase II inhibitors in tumor cells with functional p53
PublikacjaJednym z efektów wywoływanych przez związki przeciwnowotworowe w komórkach nowotworowych jest trwałe zahamowanie wzrostu, związane z pojawieniem się markerów procesu starzenia komórkowego. Proponuje się, że może to być nowy sposób na zahamowanie postępu choroby nowotworowej. W naszych badaniach wykazujemy, że zahamowanie wzrostu indukowane przez związki z grupy inhibitorów topoizomerazy II w komórkach raka płuc A549 jest związane...
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Effect of herbicides and their application dates on the content of phosphorus, potassium and total nitrogen in potato tubers
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The significance of VEGF-C/VEGFR-2 interaction in the neovascularization and prognosis of nephroblastoma (Wilms' tumour)
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Experimental study on models of cylindrical steel tanks under mining tremors and moderate earthquakes
PublikacjaThe aim of the study is to show the results of complex shaking table experimental investigation focused on the response of two models of cylindrical steel tanks under mining tremors and moderate earthquakes, including the aspects of diagnosis of structural damage. Firstly, the impact and the sweep-sine tests have been carried out, so as to determine the dynamic properties of models filled with different levels of liquid. Then,...
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Numerical investigation on behaviour of cylindrical steel tanks during mining tremors and moderate earthquakes
PublikacjaCylindrical steel tanks are important components of industrial facilities. Their safety becomes a crucial issue since any failure may cause catastrophic consequences. The aim of the paper is to show the results of comprehensive FEM numerical investigation focused on the response of cylindrical steel tanks under mining tremors and moderate earthquakes. The effects of different levels of liquid filling, the influence of non-uniform...
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A Robust Method for Sample Preparation of Gastrointestinal Stromal Tumour for LC/MS Untargeted Metabolomics
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RUMOURS RELATED TO POLITICAL INSTABILITY AND THEIR IMPACT ON IPOs. THE USE OF QUALITATIVE MODELLING WITH INCOMPLETE KNOWLEDGE
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Comparison of peptide cancer signatures identified by mass spectrometry in serum of patients with head and neck, lung and colorectal cancers: Association with tumor progression
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Cellular Effects of Selected Unsymmetrical Bisacridines on the Multicellular Tumor Spheroids of HCT116 Colon and A549 Lung Cancer Cells in Comparison to Monolayer Cultures
PublikacjaMulticellular tumor spheroids are a good tool for testing new anticancer drugs, including those that may target cancer stem cells (CSCs), which are responsible for cancer progression, metastasis, and recurrence. Therefore, we applied this model in our studies of highly active antitumor unsymmetrical bisacridines (UAs). We investigated the cellular response induced by UAs in 2D and 3D cultures of HCT116 colon and A549 lung cancer...
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Potentiation of the anti-tumour effects of Photofrin®-based photodynamic therapy by localized treatment with G-CSF
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Fluctuations of sodium, copper, zinc, iron and manganese in potato tubers in the organic and integrated production system
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Volatile organic compounds in gastrointestinal stromal tumour tissue originating from patient-derived xenografts
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A Single-Center Experience of Renal Transplantation in Elderly Patients: A Paired-Kidney Analysis
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Novel Resveratrol-Based Substrates for Human Hepatic, Renal, and Intestinal UDP-Glucuronosyltransferases
PublikacjaTrans-Resveratrol (tRes) has been shown to have powerful antioxidant, anti-inflammatory, anti-carcinogenic, and anti-aging properties; however, its use as a therapeutic agent is limited by its rapid metabolism into its conjugated forms by UDP-Glucuronosyltransferases (UGTs). The aim of the current study was to test the hypothesis that the limited bioavailability of tRes can be improved by modifying its structure to create analogs...
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Renal regulation of sodium, potassium and chloride balance in single- and twin-pregnant goats
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Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension
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Ciliary phenotyping in renal epithelial cells in a cranioectodermal dysplasia patient with WDR35 variants
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Modifiable Areal Unit Problem: the issue of determining the relationship between microparameters and a macroparameter
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THE CONCEPT OF MODELING OF SNOW IMPACT ON THE STRUCTURE OF THE SUSPENDED TAURON ARENA ROOF IN CRACOW
PublikacjaThe article presents studies and numerical simulations on modeling snow influence on TAURON ARENA suspended roof structure in Cracow. The scope of work includes experimental tests, functions solutions taking into account various cases of snow impact according to PN and EC, as well as numerical simulations for the sport and entertainment arena in the Czyzyny district. The FEM roof structure model developed in the SOFISITK software...
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Spectrum of Epithelial-Mesenchymal Transition Phenotypes in Circulating Tumour Cells from Early Breast Cancer Patients
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Effect of foliar fertilization using micronutrient fertilizers on the content of nitrates(V), nitrites(III) in potato tubers
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Effect of biodynamic preparations on the content of some mineral elements and starch in tubers of three coloured potato cultivars
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The Effect Of Reference Plane On Values Of Areal Surface Topography Parameters From Cylindrical Elements
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Investigating cellular location of aquaporins in the bovine kidney. A new view on renal physiology in cattle
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The Current Use of Mass Spectrometry in Combination with Other Separation Techniques in Drug Discovery Arena
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Redefining The Modifiable Areal Unit Problem Within Spatial Econometrics, The Case of the Scale Problem
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Redefining the Modifiable Areal Unit Problem Within Spatial Econometrics, the Case of the Aggregation Problem
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Medical Image Dataset Annotation Service (MIDAS)
PublikacjaMIDAS (Medical Image Dataset Annotation Service) is a custom-tailored tool for creating and managing datasets either for deep learning, as well as machine learning or any form of statistical research. The aim of the project is to provide one-fit-all platform for creating medical image datasets that could easily blend in hospital's workflow. In our work, we focus on the importance of medical data anonimization, discussing the...
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Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit
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Analysis of Circulating Tumor Cells in Patients with Non-Metastatic High-Risk Prostate Cancer before and after Radiotherapy Using Three Different Enumeration Assays
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Impedimetric Detection of Femtomolar Levels of Interleukin 6, Interleukin 8, and Tumor Necrosis Factor Alpha Based on Thermally Modified Nanotubular Titanium Dioxide Arrays
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DNA-reactive anticancer imidazoacridinone C-1311 is a new inhibitor of hypoxia-inducible factor 1 alpha, vascular endothelial growth factor and tumor angiogenesis
PublikacjaHypoxia-inducible factor 1 (HIF-1) plays a critical role for tumor adaptation to hypoxia and promotes angiogenesis. Antitumor imidazoacridinone C-1311 is a DNA reactive topoisomerase II and FLT3 receptor tyrosine kinase inhibitor selected for phase II clinical trials for breast cancer. Here, we demonstrate the new mechanism of C-1311 action involving HIF-1a, vascular endothelial growth factor (VEGF) and angiogenesis as additional...
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Inhibition of T-type calcium channel disrupts Akt signaling and promotes apoptosis in glioblastoma cells.
PublikacjaGlioblastoma multiforme (GBM) are brain tumors that are exceptionally resitant to both radio- and chemotherapy regimens and novel approaches to treatment are needed. T-type calcium channels are one type of low voltage-gated channel (LVCC) involved in embryonic cell proliferation and differentiation; however they are often over-expressed in tumors, including GBM. In this study, we found that inhibition of T-type Ca channels in GBM...
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THE DISTRIBUTION OF BIOACTIVE COMPOUNDS IN THE TUBERS OF ORGANICALLY GROWN JERUSALEM ARTICHOKE (HELIANTHUS TUBEROSUS L.) DURING THE GROWING PERIOD
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