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Wyniki wyszukiwania dla: MALIGNANT MELANOMA
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Intelligent system supporting diagnosis of malignant melanoma
PublikacjaMalignant melanomas are the most deadly type of skin cancers. Early diagnosis is a key for successful treatment and survival. The paper presents the system for supporting the process of diagnosis of skin lesions in order to detect a malignant melanoma. The paper describes the development process of an intel-ligent system purposed for the diagnosis of malignant melanoma. Presented sys-tem can be used as a decision support system...
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Common variants of DNA repair genes and malignant melanoma
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Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy—From Animal Models to Clinical Trials
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DEEP CONVOLUTIONAL NEURAL NETWORKS AS A DECISION SUPPORT TOOL IN MEDICAL PROBLEMS – MALIGNANT MELANOMA CASE STUDY
PublikacjaThe paper presents utilization of one of the latest tool from the group of Machine learning techniques, namely Deep Convolutional Neural Networks (CNN), in process of decision making in selected medical problems. After the survey of the most successful applications of CNN in solving medical problems, the paper focuses on the very difficult problem of automatic analyses of the skin lesions. The authors propose the CNN structure...
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Low prevalence of CDKN2A/ARF mutations among early-onset cancers of breast, pancreas and malignant melanoma in Poland
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DIAGNOSIS OF MALIGNANT MELANOMA BY NEURAL NETWORK ENSEMBLE-BASED SYSTEM UTILISING HAND-CRAFTED SKIN LESION FEATURES
PublikacjaMalignant melanomas are the most deadly type of skin cancer but detected early have high chances for successful treatment. In the last twenty years, the interest of automated melanoma recognition detection and classification dynamically increased partially because of public datasets appearing with dermatoscopic images of skin lesions. Automated computer-aided skin cancer detection in dermatoscopic images is a very challenging task...
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Antiproliferative Activity of Double Point Modified Analogs of 1,25-Dihydroxyvitamin D2 Against Human Malignant Melanoma Cell Lines
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Antiproliferative activity of side-chain truncated vitamin D analogs (PRI-1203 and PRI-1204) against human malignant melanoma cell lines
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The role of melanin pigment in melanoma
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The significance of substance P in physiological and malignant haematopoiesis
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Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management
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Proteomic profile of melanoma cell‐derived small extracellular vesicles in patients’ plasma: a potential correlate of melanoma progression
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Comprehensive analysis of microRNA expression profile in malignant glioma tissues
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New vitamin D analogs as potential therapeutics in melanoma
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Molecular differences in mitochondrial DNA genomes of dogs with malignant mammary tumours
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Nutritional Status and the Outcomes of Endoscopic Stenting in Benign and Malignant Diseases of Esophagus
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Enhanced Suppressive Activity of Regulatory T Cells in the Microenvironment of Malignant Pleural Effusions
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Differential Expression of HIF1A, EPAS1, and VEGF Genes in Benign and Malignant Ovarian Neoplasia
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Liquid Biopsy in Melanoma: Significance in Diagnostics, Prediction and Treatment Monitoring
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XPD Common Variants and their Association with Melanoma and Breast Cancer Risk
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The assessment of students’ knowledge regarding melanoma and sun-protection habits
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Proteomic Analysis of Proton Beam Irradiated Human Melanoma Cells
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ELECTROCHEMOTHERAPY COMBINED WITH STANDARD AND CO2 LASER SURGERIES IN CANINE ORAL MELANOMA
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On the role of classical and novel forms of vitamin D in melanoma progression and management
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MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
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Survivin splice variants expression in thyroid malignancy
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Cytotoxic effect on human melanoma cell lines and tyrosinase inhibition of Hottonia palustris
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublikacjaPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
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Melanoma skin cancer detection using mask-RCNN with modified GRU model
PublikacjaIntroduction: Melanoma Skin Cancer (MSC) is a type of cancer in the human body; therefore, early disease diagnosis is essential for reducing the mortality rate. However, dermoscopic image analysis poses challenges due to factors such as color illumination, light reflections, and the varying sizes and shapes of lesions. To overcome these challenges, an automated framework is proposed in this manuscript. Methods: Initially, dermoscopic...
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Fluorescence Imaging Using Methylene Blue Sentinel Lymph Node Biopsy in Melanoma
PublikacjaIntroduction: Fluorescence imaging of sentinel node biopsy in melanoma is a novel method. Both indocyanine green (ICG) and methylene blue (MB) have fl uorescent properties. The aim of this study was to present, for the fi rst time in a clinical series of patients, the possible usage of MB as a fl uorescent dye for sentinel node biopsy during surgery for melanoma. Material and methods: Twenty patients with...
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Apoptosis induction in C32 human melanoma cells by Jasione montana and its main phytoconstituents
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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
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The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
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Graphene-encapsulated iron nanoparticles as a non-viral vector for gene delivery into melanoma cells
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An Insight into the Proteome of Uveal Melanoma-Derived Ectosomes Reveals the Presence of Potentially Useful Biomarkers
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Similarities and Differences in the Protein Composition of Cutaneous Melanoma Cells and Their Exosomes Identified by Mass Spectrometry
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Deep convolutional neural network for predicting kidney tumour malignancy
PublikacjaPurpose: According to the statistics, up to 15-20% of removed solid kidney tumors turn out to be benign in postoperative histopathological examination, despite having been identified as malignant by a radiologist. The aim of the research was to limit the number of unnecessary nephrectomies of benign tumors. Methods or Background: We propose a machine-aided diagnostic system for kidney...
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Using Flavonoid Substitution Status to Predict Anticancer Effects in Human Melanoma Cancers: An In Vitro Study
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Polymer-free cubosomes for simultaneous bioimaging and photodynamic action of photosensitizers in melanoma skin cancer cells
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Endogenously generated DNA nucleobase modifications source, and significance as possible biomarkers of malignant transformation risk, and role in anticancer therapy
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Chloroacridine derivatives as potential anticancer agents which may act as tricarboxylic acid cycle enzyme inhibitors
PublikacjaThe chloroacridines affect biological forms of melanoma in different ways. Amelanotic (Ab) melanoma (with inhibited melanogenesis and higher malignancy) was particularly sensitive to the action of the chloroacridines. The Ab melanoma cells died through apoptosis and through death without caspase activation. Diminished activity of TAC enzymes was noticed among Ab melanoma cells together with ATP/NAD depletion, especially in the...
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In Vitro Anticancer Potential of Jasione montana and Its Main Components against Human Amelanotic Melanoma Cells
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Antitumor Effects of Vitamin D Analogs on Hamster and Mouse Melanoma Cell Lines in Relation to Melanin Pigmentation
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Mass Spectrometry-Based Proteomic Characterization of Cutaneous Melanoma Ectosomes Reveals the Presence of Cancer-Related Molecules
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ColorNephroNet: Kidney tumor malignancy prediction using medical image colorization
PublikacjaRenal tumor malignancy classification is one of the crucial tasks in urology, being a primary factor included in the decision of whether to perform kidney removal surgery (nephrectomy) or not. Currently, tumor malignancy prediction is determined by the radiological diagnosis based on computed tomography (CT) images. However, it is estimated that up to 16% of nephrectomies could have been avoided because the tumor that had been...
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The associations between serum VEGF, bFGF and endoglin levels with microvessel density and expression of proangiogenic factors in malignant and benign ovarian tumors
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Early Detection of Malignant Transformation in Resected WHO II Low-Grade Glioma Using Diffusion Tensor-Derived Quantitative Measures
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Fermentacja metanowa kapusty białej oraz osadu nadmiernego
PublikacjaW pracy przedstawiono wyniki badań fermentacji metanowej biomasy kapusty białej i osadu nadmiernego pobranego z oczyszczalni ścieków Saur Neptun Gdańsk S.A. Proces fermentacji prowadzono w warunkach mokrych, w sposób quaziciągły, w temperaturze 37°C. Zaobserwowano, że poddając fermentacji beztlenowej wsad zawierający kapustę białą oraz osad nadmierny można uzyskać biogaz o średnim składzie 50% metanu i 50% ditlenku węgla. Podczas...
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FERMENTACJA METANOWA MODELOWEGO WSADU KOMUNALNYCH ODPADÓW ORGANICZNYCH
PublikacjaFermentacja metanowa frakcji organicznej odpadów komunalnych pozwala na efektywny odzysk węgla z odpadów. Procesem beztlenowym jest zasadniczo fermentacja metanowa mezofilowa, jak i termofilowa, jednakże w procesie fermentacji termofilowej redukcja związków organicznych, niszczenie patogenów oraz produkcja biogazu zachodzi z większą wydajnością. Odpady komunalne charakteryzują się wysoką heterogenicznością składu, co może przyczyniać...
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Total DNA methylation as a biomarker of DNA damage and tumor malignancy in intracranial meningiomas
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