wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: PARKINSON DISEASE
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A CNN based coronavirus disease prediction system for chest X-rays
PublikacjaCoronavirus disease (COVID-19) proliferated globally in early 2020, causing existential dread in the whole world. Radiography is crucial in the clinical staging and diagnosis of COVID-19 and offers high potential to improve healthcare plans for tackling the pandemic. However high variations in infection characteristics and low contrast between normal and infected regions pose great challenges in preparing radiological reports....
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Metal nanoparticles-assisted early diagnosis of diseases
PublikacjaEarly diagnosis is essential for the effective illness treatment, but traditional diagnostic approaches inevitably have major downsides. Recent advancements in nanoparticle-based biosensors have created new opportunities for accelerating diagnosis. High surface area, exceptional sensitivity, high specificity, and optical characteristics of metal and metal oxide nanoparticles have made it possible to detect a variety of health conditions...
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Glycyrrhetinic acid and its derivatives in infectious diseases
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System of breath collection and analysis for diseases detection
PublikacjaCollection and study of composition of the exhaled air is now intensively investigated to develop non-invasive medical diagnostics based on presence of metabolic compounds in the exhaled air. The process of collecting and processing of the exhaled air must fulfill relevant conditions to achieve satisfactory results. The paper presents the system of collecting samples of exhaled breath and the proposed methods of its analysis, using...
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CORONARY ARTERY DISEASE
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Congenital Heart Disease
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DM DISEASE-A-MONTH
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Clinics in Liver Disease
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Disease Models & Mechanisms
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Journal of Acute Disease
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Foodborne Pathogens and Disease
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Infectious Disease Reports
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Chronic Respiratory Disease
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Journal of Huntingtons Disease
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Infection Disease & Health
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Immunity Inflammation and Disease
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Preventing Chronic Disease
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JRSM Cardiovascular Disease
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Neuropsychiatric Disease and Treatment
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Vascular Disease Management
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Neurodegenerative Disease Management
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Clinical Liver Disease
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Chest Disease Reports
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WIREs Mechanisms of Disease
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Digestive Disease Interventions
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Research in Plant Disease
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New Disease Reports
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Lipids in Health and Disease
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Infectious Disease Modelling
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ARCHIVES OF DISEASE IN CHILDHOOD
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Transplant Infectious Disease
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SEMINARS IN LIVER DISEASE
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Development of a tropical disease diagnosis system using artificial neural network and GIS
PublikacjaExpert systems for diagnosis of tropical diseases have been developed and implemented for over a decade with varying degrees of success. While the recent introduction of artificial neural networks has helped to improve the diagnosis accuracy of such systems, this aspect is still negatively affected by the number of supported diseases. A large number of supported diseases usually corresponds to a high number of overlapping symptoms,...
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SYNTHESIS OF PHOSPHORUS TACRINE ANALOGUES AS A NEW POTENTIAL ANTI-ALZHEIMER’S DISEASE AGENTS
PublikacjaA series of novel phosphorus tacrine derivatives was obtained in three steps, including synthesis of 9-chlorotacrine, connection of 9-chlorotacrine with hexamethylenediamine, 1,8-diaminooctane and 1,12-diaminododecane linkers and reaction of obtained tacrine diamine analogues with corresponding acid ester to give nine tacrine organophosphorus compounds. All of the obtained final structures were characterized by 1H NMR, 13C NMR,...
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Investigating the disease- modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
PublikacjaAlzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day-to-day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability....
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Investigating the disease‐modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
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Exhaled nitric oxide in smokers and former smokers with chronic obstructive pulmonary disease
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Chromoblastomycosis as an endemic disease in temperate Europe: first confirmed case and review of the literature
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Analysis of Serum of Patients With Alzheimer’s Disease for the Level of Advanced Glycation End Products
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Ambulatory pulse pressure and its contributors in autosomal dominant polycystic kidney disease
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The Relationship Between Gene Polymorphisms and Dipping Profile in Patients With Coronary Heart Disease
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Ultra-rare ultra-care: The unique burden of ultra rare disease caregiving
PublikacjaBackground: We sought to assesses the impact of caring for children with ultra rare diseases (URDs) on familycarers and to analyse the way these experiences differ among the caregivers of children diagnosed throughprenatal or newborn screening, and those with symptom-based diagnosis.Methods: A total of 200 caregivers of 219 URDs children completed an on-line survey regarding the challengesand experiences...
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Chlorpromazine-induced hyperprolactinemia in a young female and its relation with fibrocystic breast disease
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Molecular Mechanisms Associated with ROS-Dependent Angiogenesis in Lower Extremity Artery Disease
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Gender-Related Differences in Trimethylamine and Oxidative Blood Biomarkers in Cardiovascular Disease Patients
PublikacjaGender differences in the burden of cardiovascular disease (CVD) have been observed worldwide. In this study, plasmatic levels of trimethylamine (TMA) and blood oxidative biomarkers have been evaluated in 358 men (89 controls and 269 CVD patients) and 189 women (64 control and 125 CVD patients). The fluorescence technique was applied to determine erythrocyte membrane fluidity using 1,6-diphenyl-1,3,5-hexatriene (DPH) and Laurdan,...
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Deep Infiltrating Endometriosis in Adolescence: Early Diagnosis and Possible Prevention of Disease Progression
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F05 Nine Hole Peg Test As A Measure Of Visuomotor Coordination In Huntington's Disease
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Expert System as a classification method for optimal Legg-Calve-Perthes Disease treatment
PublikacjaZaproponowano utworzenie systemu eksperckiego jako metody klasyfikacji w prognozowaniu dowolnej formy leczenia dzieci z chorobą Legg-Calve-Perthesa. Obecnie nie ma jednego optymalnego sposobu leczenia choroby Perhtes'a i proponowana metoda jest próbą utworzenia wymiernego i uniwersalnego narzędzia, które będzie stanowiło podstawę przy podejmowaniu decyzji o najlepszym sposobie leczenia chorego stawu biodrowego. System ekspercki,...
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Microbial diversity of inflamed and noninflamed gut biopsy tissues in inflammatory bowel disease.
PublikacjaBACKGROUND: Inflammatory bowel disease (IBD) is a chronic gastrointestinal condition without any known cause or cure. An imbalance in normal gut biota has been identified as an important factor in the inflammatory process. METHODS: Fifty-eight biopsies from Crohn's disease (CD, n = 10), ulcerative colitis (UC, n = 15), and healthy controls (n = 16) were taken from a population-based case-control study. Automated ribosomal intergenic...
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DIGESTIVE DISEASES
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CEREBROVASCULAR DISEASES
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AVIAN DISEASES
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Kidney Diseases
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Autoimmune Diseases
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Genes & Diseases
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DISEASES OF THE ESOPHAGUS
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Rare Diseases
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Breast Diseases
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Neurodegenerative Diseases
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Bile Acids: Key Players in Inflammatory Bowel Diseases?
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Fecal Serine Protease Profiling in Inflammatory Bowel Diseases
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The role of interleukin 16 in the pathogenesis of selected skin diseases
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Editorial “Nutrition and Dietary Intake for Liver-Related Diseases”
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Role of omentin and vaspin in metabolic diseases in association with psoriasis
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Genistein: a natural isoflavone with a potential for treatment of genetic diseases
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Genistein: a lysosomal stimulator for treatment of various lysosomal diseases
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Cognitive Abilities of Alzheimers Disease Transgenic Mice are Modulated by Social Context and Circadian Rhythm
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Evaluating the Role of Circulating Dendritic Cells in Methimazole-Treated Pediatric Graves’ Disease Patients
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Regulatory B Cells Involvement in Autoimmune Phenomena Occurring in Pediatric Graves’ Disease Patients
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Environmental Factors and the Risk of Developing Type 1 Diabetes—Old Disease and New Data
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Evaluating the Role of Circulating Dendritic Cells in Methimazole-Treated Pediatric Graves’ Disease Patients
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Novel design of sodium alginate based absorbable stent for the use in urethral stricture disease
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Tackling Alzheimer's disease: Hypothetical synergism between anti-inflammatory and anti-diabetic agents
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Stress and self-image in multiple sclerosis patients and selected positive aspects of struggling with the disease
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Association between Age at Diagnosis of Graves' Disease and Variants in Genes Involved in Immune Response
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Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
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Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease—A Meta-Analysis
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Effect of intensive lipid-lowering therapies on cholinesterase activity in patients with coronary artery disease
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Religiosity and Attitudes towards Health, Disease, Death and the Use of Stimulants among Jehovah’s Witnesses
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Primary cutaneous anaplastic large-cell lymphoma in a patient with Hodgkin’s disease – case report
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Olfactory Dysfunction in Patients With Relapsing-Remitting Multiple Sclerosis Treated With Disease-Modifying Therapies
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A response to “Cardiovascular disease and obstructive sleep apnea: an underappreciated role for increased platelet activity?”
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Hypertension and cardiovascular disease in women: Progress towards better understanding of gender‐specific differences?
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Craniofacial proportions in children with adenoid or adenotonsillar hypertrophy are related to disease duration and nasopharyngeal obstruction
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Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study
PublikacjaThe early atherosclerotic lesions develop by the accumulation of arterial foam cells derived mainly from cholesterol-loaded macrophages. Therefore, cholesterol and cholesteryl ester transfer protein (CETP) have been considered as causative in atherosclerosis. Moreover, recent studies indicate the role of trimethylamine N-oxide (TMAO) in development of cardiovascular disease (CVD). The current study aimed to investigate the association...
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Analysis of exhaled breath for dengue disease detection by low-cost electronic nose system
PublikacjaThis paper presents a procedure and a set-up of an electronic nose system analyzing exhaled breath to detect the patients suffering from dengue – a mosquito-borne tropical disease. Low-power resistive gas sensors (MiCS-6814, TGS8100) were used to detect volatile organic compounds (VOCs) in the exhaled breath. The end-tidal phase of patients exhaled breath was collected with a BioVOCTM breath sampler. Two strategies were assessed...
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Structural Studies of Thyroid Peroxidase Show the Monomer Interacting With Autoantibodies in Thyroid Autoimmune Disease
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Supporting Gastroesophageal Reflux Disease Diagnostics by Using Wavelet Analysis in Esophageal pH-Metry
PublikacjaThis paper presents a new approach to computer supported esophageal pH-metry measurement analysis performed in order to diagnose gastroesophageal reflux disease. In this approach wavelet analysis was used to analyse the esophageal pH-metry course. The research was performed on three groups of pH-metry courses: whole 24-hour pH-metry course, sleep only pH-metry course and 20 minutes after the end of a meal pH-metry course. After...
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Metals in the environment as risk factors for infectious diseases: gaps and opportunities
PublikacjaThis chapter aims to provide insights into current knowledge and gaps in our understanding of the influence that trace metals in the environment have on the pathogenesis of infectious diseases. By reducing immune function, trace metal deficiencies may substantially contribute to the global burden of diarhea, pneumonia, and malaria. Improved methods and biomarkers for assessing the risk of trace metals deficiencies and toxicities...
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Knowledge and Attitudes of Future Healthcare Professionals Toward Rare Diseases
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Dendrimer Structure Diversity and Tailorability as a Way to Fight Infectious Diseases
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Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases
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Factors and processes modulating phenotypes in neuronopathic lysosomal storage diseases
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Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
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Therapeutic Potential of Carnosine and Its Derivatives in the Treatment of Human Diseases
PublikacjaDespite significant progress in the pathogenesis, diagnosis, treatment, and prevention of cancer and neurodegenerative diseases, their occurrence and mortality are still high around theworld. The resistance of cancer cells to the drugs remains a significant problem in oncology today,while in the case of neuro-degenerative diseases, therapies reversing the process are still yet to be found. Furthermore, it is important to seek new...
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Sample preparation and recent trends in volatolomics for diagnosing gastrointestinal diseases
PublikacjaThe analysis of the human volatilome can be successfully used for rapid and non-invasive diagnostics of gastrointestinal diseases. However, the introduction of techniques based on detection of volatiles is limited, among other factors, by difficulties which arise during the sampling stage and instrumental analysis. The aim of this article was to review and discuss medical and analytical literature on the analysis of volatiles in...
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Mitochondrial DNA copy number and trimethylamine levels in the blood: New insights on cardiovascular disease biomarkers
PublikacjaAmong cardiovascular disease (CVD) biomarkers, the mitochondrial DNA copy number (mtDNAcn) is a promising candidate. A growing attention has been also dedicated to trimethylamine-N-oxide (TMAO), an oxidative derivative of the gut metabolite trimethylamine (TMA). With the aim to identify biomarkers predictive of CVD, we investigated TMA, TMAO, and mtDNAcn in a population of 389 coronary artery disease...
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Integrative multiomics study for validation of mechanisms in radiation-induced ischemic heart disease in Mayak workers
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Professional activity, gender and disease-related emotions: The impact on parents' experiences in caring for children with phenylketonuria
PublikacjaIntroduction: Clinical management of rare diseases often fails to acknowledge the challenges faced by caregivers.Whilst management of phenylketonuria (PKU) may not be considered as dire as other conditions, most studiesprimarily concentrate on clinical issues, dietary adherence, or the quality of life of the PKU patients, leavingcaregivers in the background. The aim of the study was to evaluate the psychosocial...
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Ovocystatin Induced Changes in Expression of Alzheimer’s Disease Relevant Proteins in APP/PS1 Transgenic Mice
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