Filters
total: 1321
-
Catalog
- Publications 978 available results
- Journals 103 available results
- Publishing Houses 4 available results
- People 37 available results
- Inventions 18 available results
- Projects 24 available results
- Research Teams 6 available results
- e-Learning Courses 65 available results
- Events 1 available results
- Open Research Data 85 available results
displaying 1000 best results Help
Search results for: pal
-
PROFESSIONAL PRACTICE [2020/21]
e-Learning Courses -
Targeting yeast topoisomerase II by imidazo and triazoloacridinone derivatives resulting in their antifungal activity
PublicationFungal pathogens are considered as serious factors for deadly diseases and are a case of medical concern. Invasive fungal infections also complicate the clinical course of COVID-19, leading to a significant increase in mortality. Furthermore, fungal strains' multidrug resistance has increased the demand for antifungals with a different mechanism of action. The present study aimed to identify antifungal compounds targeting yeast...
-
The Chemical and Biological Properties of Nanohydroxyapatite Coatings with Antibacterial Nanometals, Obtained in the Electrophoretic Process on the Ti13Zr13Nb Alloy
PublicationThe risk of an early inflammation after implantation surgery of titanium implants has caused the development of different antimicrobial measures. The present research is aimed at characterizing the effects of nanosilver and nanocopper dispersed in the nanohydroxyapatite coatings, deposited on the Ti13Zr13Nb alloy, and on the chemical and biological properties of the coatings.The one-stage deposition process was performed by the...
-
Amberlyst-15 catalysed synthesis of novel indole derivatives under ultrasound irradiation: Their evaluation as serotonin 5‑HT2C receptor agonists
Publication -
In Vitro Evaluation of Polihexanide, Octenidine and NaClO/HClO-Based Antiseptics against Biofilm Formed by Wound Pathogens
Publication -
In silico assessment and sonochemical synthesis of 2-alkynyl 3-chloropyrazines as prospective ligands for SARS-CoV-2
PublicationThe recent global pandemic caused by COVID-19 has triggered an intense effort worldwide towards the development of an effective cure for this disease. In our effort we have explored the 2-alkynyl substituted 3-chloropyrazine framework as a potential template for the design of molecules for this purpose. Our strategy was supported by the in silico studies of representative compounds to assess their binding affinities via docking...
-
Assessment of antibiotic resistance and biofilm formation of Enterococcus species isolated from different pig farm environments in Poland
Publication -
Replicating DNA by cell factories: roles of central carbon metabolism and transcription in the control of DNA replication in microbes, and implications for understanding this process in human cells
Publication -
Principles of target DNA cleavage and the role of Mg2+ in the catalysis of CRISPR–Cas9
PublicationAt the core of the CRISPR–Cas9 genome-editing technology, the endonuclease Cas9 introduces site-specific breaks in DNA. However, precise mechanistic information to ameliorate Cas9 function is still missing. Here, multimicrosecond molecular dynamics, free energy and multiscale simulations are combined with solution NMR and DNA cleavage experiments to resolve the catalytic mechanism of target DNA cleavage. We show that the conformation...
-
Study on stable dispersion of functionalized Fe-MWCNTs
Publication -
Novel method controlled synthesis of silica coated carbon nanotubes
Publication -
Synthesis and photocatalytic performance of TiO2 nanospheres–graphene nanocomposite under visible and UV light irradiation
Publication -
Inner-Tube Chirality Determination for Double-Walled Carbon Nanotubes by Scanning Tunneling Microscopy
Publication -
Surfactant free fractions of metallic and semiconducting single-walled carbon nanotubes via optimised gel chromatography
Publication -
Single-walled carbon nanotubes fractionation via electrophoresis
Publication -
Carbon nanotubes linked with pitavastatin: synthesis and characterisation
Publication -
Synthesis of nickel nanocapsules and carbon nanotubes via methane CVD
Publication -
Studies on the Preparation and Characterisation of Carbon Nanostructures
Publication -
Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes
PublicationNew promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groupsincluding 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imi-dazoacridinone and triazoloacridinone derivatives with 1-nitroacridine compounds linked with anaminoalkyl chain. Cytotoxicity screening revealed the high potency of these compounds against severaltumor cell lines. Particularly, imidazoacridinone-1-nitroacridine...
-
pH-Responsive Drug Delivery Nanoplatforms as Smart Carriers of Unsymmetrical Bisacridines for Targeted Cancer Therapy
PublicationSelective therapy and controlled drug release at an intracellular level remain key challenges for effective cancer treatment. Here, we employed folic acid (FA) as a self-navigating molecule in nanoconjugates containing quantum dots (QDs) and β-cyclodextrin (β-CD) for the delivery of antitumor unsymmetrical bisacridine compound (C-2028) to lung and prostate cancers as well as normal cells. The bisacridine derivative can form the...
-
Microbiota-derived metabolites in colorectal cancer patients in preoperative period
PublicationShort-chain fat-ty acids (SCFAs) are microbial derived metabo-lites, which have multiple beneficial properties. The amount of SCFAs depends on several fac-tors, such as age, diet (mainly intake of dietary fiber), and overall health condition. The normal proportion between SCFAs is 3:1:1 for acetate, proprionate and butyrate, respectively. In col-orectal cancer (CRC) patients, microbiota alter-ations have been shown. Consequently,...
-
Most Frequent Organic Interactions Compressed in Toluene
Publication -
Influence of several biodegradable components added to pure and nanosilver-doped PMMA bone cements on its biological and mechanical properties
PublicationAcrylic bone cements (BC) are wildly used in medicine. Despite favorable mechanical properties, processability and inject capability, BC lack bioactivity. To overcome this, we investigated the effects of selected biodegradable additives to create a partially-degradable BC and also we evaluated its combination with nanosilver (AgNp). We hypothesized that using above strategies it would be possible to obtain bioactive BC. The Cemex...
-
Synthesis of 3-indolylmethyl substituted (pyrazolo/benzo)triazinone derivatives under Pd/Cu-catalysis: Identification of potent inhibitors of chorismate mutase (CM)
Publication -
Ultrasound assisted rapid synthesis of mefenamic acid based indole derivatives under ligand free Cu-catalysis: Their pharmacological evaluation
Publication -
Solid and liquid fractionation of sugarcane and Agave bagasse during ozonolysis and enzymatic hydrolysis: Impact on biohydrogen and biogas production
PublicationSustainable and cost-efficient lignocellulosic biomass-to-energy bioprocesses require assessing the main components released during biomass fractionation. This study assessed the mesophilic biochemical potential of biohydrogen (BHP) and methane production (BMP) from sugarcane bagasse (SCB) and cooked (CAB) and uncooked (UAB) Agave bagasse. A systematic comparative analysis was performed for the liquid and solid fractions derived...
-
Identification and management of the hypertensive patient with elevated heart rate: statement of a European Society of Hypertension Consensus Meeting
Publication -
Szkolenie z regulaminu studiów oraz praw i obowiązków studenta/Training concerning study regulations, student rights and responsibilities 2022/2023
e-Learning Courses -
Battle wound as a probable cause of the death of an early medieval horse in Ostrów Lednicki, Poland
Publication -
Ocena nośności pali na podstawie badań sondą CPT.**2003, 196 s. 16 rys. 68tab. 85 wykr. bibliogr. 129 poz. maszyn. Rozprawa doktorska /30.06.2003/ P. Gdań. WBWiIŚ. Promotor: dr hab. inż. K. Gwizdała, prof. PG.
Publication.
-
Modifying CVD synthesised carbon nanotubes via the carbon feed rate
Publication -
Iron filled carbon nanostructures from different precursors
Publication -
Filling of carbon nanotubes for bio‐applications
Publication -
Iron filled singlewalled carbon nanotubes – synthesis and characteristic properties
Publication -
Effect of Functionalization of Carbon Nanotubes with Psychosine on Complement Activation and Protein Adsorption
Publication -
Synthesis and electronic properties of B-doped single wall carbon nanotubes
Publication -
Intraoperative, Radio-Guided Sentinel Lymph Node Mapping in 110 Nonsmall Cell Lung Cancer Patients
Publication -
Opinia naukowo-techniczna dotycząca przyczyn obniżonej nośności pali CFA 800 mm wykonanych pod posadowienie podpory P10 wiaduktu drogowego nad linią kolejową w Cieplewie k. Pruszcza Gdańskiego wraz z propozycją zapewnienia nośności fundamentu podpory
PublicationPrzeprowadzono analizę wyniku próbnego obciążenia pala CFA pod posadowienie przyczółka wiaduktu. Przeanalizowano budowę podłoża gruntowego na podstawie dokumentacji archiwalnych i na podstawie własnych badań metodą CPT. Określono przyczyny obniżonej nośności wykonanych pali. Zaproponowano sposób zapewnienia wymaganej nośności fundamentu przyczółka.
-
Zespół Robotyki i Systemów Mechatroniki
Research Teams1. Robotyka stacjonarna oraz mobilna; 2. Zastosowanie metod wibracyjnych do detekcji uszkodzeń elementów maszyn i urządzeń mechatroniki; 3. Wykorzystanie energii elektrycznej gromadzonej w czasie pracy systemów mechatroniki zbudowanych z materiału piezoelektrycznego; 4. Projektowanie układów, urządzeń i systemów automatyki elektroenergetycznej.
-
Propargylamines in Pd/Cu-catalyzed tandem coupling-cyclization-N-deprotection in a single pot: Construction of N-unsubstituted vs N-sulfonyl indole ring
Publication -
The catalytic potential of high-κ dielectrics for graphene formation
Publication -
Determination of the minimum inhibitory concentration of C-1311 derivatives (C-1296, C-1410, Compound 1, Compound 1-R8) against Candida strains
Open Research DataThe datasets contain the results of determining the minimum inhibitory concentration of imidazoacridinone derivatives against C. albicans ATCC 10231, C. glabrata ATCC 90030, C. krusei ATCC 6258 and C. parapsilosis ATCC 22019 and C. albicans clinical strains by the modified M27-A3 specified by the CLSI.
-
Killing kinetics analysis of C-1311 derivative with octaarginine (Compound 1-R8) against Candida albicans
Open Research DataThe datasets contain the results of killing kinetics analysis of imidazoacridinone derivative and fluconazole against C. albicans ATCC 10231. The suspensions of Candida albicans ATCC 10231 cells (500 µL) in RPMI 1640 at cell density of 104 cells /mL were added to 500 µL of RPMI 1640 medium with various concentrations of the compounds, corresponding...
-
The absorption and fluorescence spectra of novel bisacridines (IKE15-19, IKE21) and IE10, potential antifungal agents
Open Research DataOptical measurements of novel bisacridines (IKE15-19, IKE21) and IE10 were conducted. The absorption spectra were recorded from 300 to 800 nm. The fluorescence emission spectra were determined with excitation and emission wavelengths described in the file. All measurements were recorded using a multiplate reader, Tecan Spark 10M.
-
Effect of novel bisacridines (IKE16, IKE18, IKE19, IKE21) and IE10 on the biofilm formation of C. albicans ATCC 10231 cells
Open Research DataThe datasets contain the results of the impact of novel bisacridines (IKE16, IKE18, IKE19, IKE21) and IE10 on the biofilm formation of Candida albicans strain ATCC 10231 cells. Photographic documentation prepared with the TECAN Spark 10M titration plate reader.
-
The processing of staphylococcal biofilm images from Fluorescence and Confocal Microscopy to assess in vitro efficacy of antiseptic molecules
Publication -
Formation of novel nanostructures using carbon nanotubes as a frame
Publication -
Silver filled single-wall carbon nanotubes—synthesis, structural and electronic properties
Publication -
Analiza popytu dla potrzeb zarządzania cenami na przykładzie rynku paliw wPolsce.**2002, 180 s. 32 rys. 32 tab. 32 wykr. bibliogr. 76 poz. maszyn. Rozprawa doktorska (12.06.2002). P. Gdań. Wydz. ZiE. Promotor: dr hab. Jerzy C. Ossowski, prof. nadzw. PG
Publication.
-
Novel isatin–indole derivatives as potential inhibitors of chorismate mutase (CM): their synthesis along with unexpected formation of 2-indolylmethylamino benzoate ester under Pd–Cu catalysis
Publication