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Search results for: COMPRESSION THERAPY
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Epigenetic-Based Therapy—A Prospective Chance for Medulloblastoma Patients’ Recovery
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Newborn screening and gene therapy in SMA: Challenges related to vaccinations
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The p53-mediated cytotoxicity of photodynamic therapy of cancer: Recent advances
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Documentation of endpoint prevention with combination therapy in hypertension is urgently needed
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Updated ESH position paper on interventional therapy of resistant hypertension
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Dosimetric evaluation of a novel polymer gel dosimeter for proton therapy
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VEGF – targeted therapy for the treatment of cervical cancer – literature review
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Diagnostic pure transgastric NOTES in an intensive therapy unit patient
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Between therapy effect and false-positive result in animal experimentation
PublicationDespite the animal models’ complexity, researchers tend to reduce the number of animals in experiments for expenses and ethical concerns. This tendency makes the risk of false-positive results, as statistical significance, the primary criterion to validate findings, often fails if testing small samples. This study aims to highlight such risks using an example from experimental regenerative therapy and propose a machine-learning...
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TRF1 and TRF2: pioneering targets in telomere-based cancer therapy
PublicationThis article presents an in-depth exploration of the roles of Telomere Repeat-binding Factors 1 and 2 (TRF1 and TRF2), and the shelterin complex, in the context of cancer biology. It emphasizes their emerging significance as potential biomarkers and targets for therapeutic intervention. Central to the shelterin complex, TRF1 and TRF2 are crucial in maintaining telomere integrity and genomic stability, their dysregulation often...
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Bacteriophages as potential tools for use in antimicrobial therapy and vaccine development
PublicationThe constantly growing number of people suffering from bacterial, viral, or fungal infections, parasitic diseases, and cancers prompts the search for innovative methods of disease prevention and treatment, especially based on vaccines and targeted therapy. An additional problem is the global threat to humanity resulting from the increasing resistance of bacteria to commonly used antibiotics. Conventional vaccines based on bacteria...
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Overcoming Phobias: Harnessing the Power of Immersive Virtual Reality Therapy
PublicationThe goal of the chapter was to review the different therapeutic techniques used in the treatment of various forms of phobias, with particular emphasis on virtual reality treatment. We define different types of phobias, including social ones. We also describe treatment techniques – adopted from behavioral therapy – which have been developed to aid the treatment of phobias. Particular emphasis has been placed on the flooding, implosive...
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Intelligent Lossy Compression Method of Providing a Desired Visual Quality for Images of Different Complexity
PublicationLossy compression plays a vital role in modern digital image processing for producing a high compression ratio. However, distortion is unavoidable, which affects further image processing and must be handled with care. Providing a desired visual quality is an efficient approach for reaching a trade-off between introduced distortions and compression ratio; it aims to control the visual quality of the decompressed images and make...
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Behaviour of asphalt concrete in cyclic and static compression creep test with and without lateral confinement
PublicationArtykuł przedstawia wpływ metodyki badań na określanie parametrów betonu asfaltowego. Wykazano, że badania pełzania bez skrępowania bocznego w większym stopniu uwypuklają wpływ asfaltu na parametry badanego betonu asfaltowego natomiast w badaniach ze skrępowaniem bocznym, zarówno rola asfaltu jak i szkieletu mineralnego jest uwzględniana przy ocenie parametrów betonu asfaltowego. Ponadto wykazano, że lepszymi miarami do oceny betonu...
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Adaptive Method of Raster Images Compression and Examples of Its Applications in the Transport Telematic Systems
PublicationThe paper presents a concept and exemplary application of an adaptive method of compression of raster images which may be applied, i.a. in ITS systems. The described method allows to improve the efficiency of systems belonging to ITS category, which require transmission of large volumes of image data through telecommunications networks. The concept of the adaptive method of compression of raster images described in the paper uses...
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The hydration of selected biologically relevant molecules – the temperature effect on apparent molar volume and compression
PublicationThe densities and sound velocities at T = (288.15, 293.15, 298.15, 303.15 and 308.15) K were measured for aqueous solutions of glycine, trimethylamine-N-oxide, taurine and N-methylacetamide. From these data, the apparent molar volumes, V the apparent molar isentropic compressions, KS,, and the Passynski hydration numbers of solutes were determined. The concentration dependencies of the calculated quantities, their limiting values...
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Microstructural evolution of 6061 aluminium alloy subjected to static and dynamic compression at low temperature
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The inverse problem in a hyperbolic section radial compressor.
PublicationNa przykładzie wirnika sprężarki porównano wyniki rozwiązania zadania odwrotnego w ramach modelu 2D prowadzącego do kształtu wirnika, z zadaniem prostym, w ramach modelu 3D, dla skonstruowanego wirnika na bazie modelu 2D.Zasadniczym celem było uzyskanie równomiernych (bez oderwań) pól parametrów w obrębie wirnika sprężarki. Pokazano jak zmiana obrysu wirnika, z klasycznego kształtu stożkowego na hiperboliczny, wpłynąć może na...
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Smart Pen - new multimodal computer control tool for graphomotorical therapy
PublicationW sytuacji, gdy około 15% populacji uczniów wykazuje cechy dyslektyczne, koniecznością staje się wyposażenie szkół w efektywne narzędzia do diagnozy i terapii tego rodzaju zaburzeń. Dzięki wykorzystaniu tabletu i specjalnie skonstruowanego długopisu wyposażonego w czujniki nacisku uzyskano możliwość monitorowania wielu parametrów, które do tej pory były dla terapeutów całkowicie niedostępne (np. pomiar nacisku na podłoże czy ścisku...
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H2AX phosphorylation, its role in DNA damage response and cancer therapy
PublicationDouble-strand breaks (DSBs) are the most deleterious DNA lesions, which, if left unrepaired, may have severe consequences for cell survival, as they lead to chromosome aberrations, genomic instability, or cell death. Various physical, chemical, and biological factors are involved in DSB induction. Cells respond to DNA damage by activating the so-called DNA damage response (DDR), a complex molecular mechanism developed to detect...
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Cortisol Levels in Infants with Central Coordination Disorders during Vojta Therapy
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Cortisol Levels in Infants with Central Coordination Disorders during Vojta Therapy
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Monitoring the Efficiency of Equilibrium Reactions During Therapy in Children With Postural Disorders
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Monitoring the Efficiency of Equilibrium Reactions During Therapy in Children With Postural Disorders
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Effect of renal replacement therapy on selected arachidonic acid derivatives concentration
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Investigation of photothermolysis therapy of human skin diseases using optical phantoms
PublicationDermatological diseases, such as neurofibroma (Recklinghausen disease) or hemangiomas can be efficiently treated using photothermolysis from laser irradiation. We have utilized a developed 975 nm fiber diode laser as a low-cost alternative over common Nd:YAG lasers. This paper describes the investigations of interaction of 975 nm diode laser radiation-pulses with optical skin phantoms which were designed and manufactured in our...
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Tinnitus Therapy Based on High-Frequency Linearization Principles - Preliminary Results
PublicationThe aim of this work is to present problems related to tinnitus symptoms, its pathogenesis, hypotheses on tinnitus causes, and therapy treatment to reduce or mask the phantom noise. In addition, the hypothesis on the existence of parasitic quantization that accompanies hearing loss has been recalled. Moreover, the paper describes a study carried out by the Authors with the application of high-frequency dither having specially formed...
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Effect of brefeldin A and castanospermine on resistant cell lines as supplements in anticancer therapy
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Dual-task exercise as a therapy for executive motor function in Parkinson’s disease
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Nurses and Pharmacists in Interdisciplinary Team of Health Care Providers in Photodynamic Therapy
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Antithrombotic therapy in patients with atrial fibrillation undergoing percutaneous coronary intervention
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Theophylline Therapy for Near-Fatal Cheyne–Stokes Respiration: A Case Report
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Radiation therapy dosimetry using magnetic resonance imaging of polymer gels
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Inhibitory mikrotubul w terapii przeciwnowotworowej = Inhibitors of microtubule in cancer therapy
PublicationW artykule opisano inhibitory mikrotubul, różnorodne związki chemiczne, znajdujące się w zaawansowanych przedklinicznych i wstępnych badaniach klinicznych. Pośród nich na uwagę zasługują półsyntetyczne analogi taksolu, substancje pochodzenia naturalnego, takie jak: epotilony, kombretastatyny, kolchinoidy, dolastatyny oraz syntetyczne związki o niskim ciężarze czasteczkowym: heterokombretastatyny, sulfonamidy, fenostatyny, pochodne...
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The effect of renal replacement therapy on the concentration of selected arachidonic acid derivatives
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COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?
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Compressive Strength and Leaching Behavior of Mortars with Biomass Ash
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Two-Stage Golomb – Context-Adaptive Binary Arithmetic Coders Coding in Lossless Image Compression
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Multilevel model order reduction with generalized compression of boundaries for 3-d FEM electromagnetic analysis
PublicationThis paper presents a multilevel Model Order Reduction technique for a 3-D electromagnetic Finite Element Method analysis. The reduction process is carried out in a hierarchical way and involves several steps which are repeated at each level. This approach brings about versatility and allows one to efficiently analyze complex electromagnetic structures. In the proposed multilevel reduction the entire computational domain is covered...
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Mathematical model defining volumetric losses of hydraulic oil compression in a variable capacity displacement pump
PublicationThe objective of the work is to develop the capability of evaluating the volumetric losses of hydraulic oil compression in the working chambers of high pressure variable capacity displacement pump. Volumetric losses of oil compression must be determined as functions of the same parameters, which the volumetric losses due to leakage, resulting from the quality of design solution of the pump, are evaluated as dependent on and also...
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Compression and Fatigue Testing of High-Strength Thin Metal Sheets by Using an Anti-Buckling Device
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Impact of a CPRMeter feedback device on chest compression quality performer by nurses: A randomized crossover study
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A pilot study of mechanical chest compression with the LifeLine ARM device during simulated cardiopulmonary resuscitation
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Review the Ultimate Strength According to Welding Deformation Criteria of Thin Plates Under In-plane Compression
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Impact performance of novel multi-layered prepacked aggregate fibrous composites under compression and bending
PublicationMulti-layered Prepacked aggregate fibrous composite (MLPAFC) is a new type of concrete, which is prepared in two subsequent stages of aggregate-fibre skeleton prepacking and cementitious grouting. In this study, ten MLPAFC mixtures were prepared in three subsequent layers incorporating different contents of four different types of steel fibres. Long and short hooked-end and crimped steel fibers were adopted with 3.0 and 1.5% dosages...
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Numerical Modelling for Prediction of Compression Index from Soil Index Properties in Jimma town, Ethiopia
PublicationIn this study, correlations are developed to predict compression index (Cc) from index parameters so that one can be able to model Jimma soils with compression index using simple laboratory tests. Undisturbed and disturbed soil samples from twelve different locations in Jimma town were collected. Laboratory tests like specific gravity, grain size analysis, Atterberg limit, and one-dimensional consolidation test for a total of twenty-four...
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Finite element study of patterns of shear zones in granular bodies during plane strain compression
PublicationW artykule przedstawiono obliczenia efektów skali na nośność fundamentu na piasku. Obliczenia wykonano przy pomocy mikropolarnego prawa hipoplastycznego. W obliczeniach wykorzystano stochastyczne rozkłady początkowego wskaźnika porowatości według rozkładu Gaussa.
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Modeling of a cyclic plane strain compression-extension test in granular bodies within a polar hypoplasticity
PublicationW artykule przedstawiono wyniki numerycznej analizy wpływu cyklicznego ściskania-rozciągania na lokalizację odkształceń stycznych w materiałach granulowanych. Obliczenia wykonano stosując metodę elementów skończonych i mikropolarne hipoplastyczne prawo konstytutywne. Analizę przeprowadzono dla piasku zagęszczonego i luźnego dla różnych amplitud obciążenia.
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Application of the 3D DEM in the modelling of fractures in pre-flawed marble specimens during uniaxial compression
PublicationPrzedstawiono w tym artykule wyniki modelowania pęknięć w cylindrycznych próbkach marmurowych ze wstępnymi nacięciami w czasie jednoosiowego ściskania . Zastosowano metodę elementów dyskretnych (DEM). Zbadano propagację i koalescencję pęknięć w próbkach marmuru z istniejącymi otwartymi nacięciami pod różnymi kątami do poziomu. Wyniki numerycznych symulacji trójwymiarowych (3D) zostały bezpośrednio porównane z badaniami laboratoryjnymi....
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2D inverse solution for cone-shaped centrifugal compressor
PublicationWprowadzono stożkowy układ współrzędnych dla opisania obszaru wirnika sprężarki promieniowej. W takim układzie został sformułowany problem odwrotny. Oznacza to, że dla założonej jednej rodziny powierzchni prądu (S1) w formie powierzchni stożkowych druga rodzina (S2) jest znajdywana w drodze rozwiązania układu równań zachowania. Pokazano w jaki sposób rozwiązanie zależy od warunków brzegowych. Przedstawiona metoda jest przydatna...