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Search results for: CATHETER-INDUCED CORONARY DISSECTION
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Metabolic Profiling of Jasminum grandiflorum L. Flowers and Protective Role against Cisplatin-Induced Nephrotoxicity: Network Pharmacology and In Vivo Validation
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Oxidative stress induced by 4-methyl-1-nitroacridine derivative C-1748 (Capridine B) in human colon cancer cells
PublicationZbadano wpływ pochodnej C-1748 (Capridine B) na indukcję stresu oksydacyjnego w komórkach ludzkich raków jelita grubego HCT-8 i HT29. W tym celu wykorzystano technikę cytometrii przepływowej z zastosowaniem barwników fluorescencyjnych H2DCFDA i DHR 123. W komórkach traktowanych pochodną C-1748 dochodziło do generowania reaktywnych form tlenu. Ponadto, pochodna C-1748 nie indukowała znaczącego spadku zawartości zredukowanej formy...
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Do not die, become senescent: a new type of cellular resistance induced by topoisomerase II inhibitors in tumor cells with functional p53
PublicationJednym z efektów wywoływanych przez związki przeciwnowotworowe w komórkach nowotworowych jest trwałe zahamowanie wzrostu, związane z pojawieniem się markerów procesu starzenia komórkowego. Proponuje się, że może to być nowy sposób na zahamowanie postępu choroby nowotworowej. W naszych badaniach wykazujemy, że zahamowanie wzrostu indukowane przez związki z grupy inhibitorów topoizomerazy II w komórkach raka płuc A549 jest związane...
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Changes in Epigenetic Patterns Related to DNA Replication in Vicia faba Root Meristem Cells under Cadmium-Induced Stress Conditions
PublicationExperiments on Vicia faba root meristem cells exposed to 150 µM cadmium chloride (CdCl2) were undertaken to analyse epigenetic changes, mainly with respect to DNA replication stress. Histone modifications examined by means of immunofluorescence labeling included: (1) acetylation of histone H3 on lysine 56 (H3K56Ac), involved in transcription, S phase, and response to DNA damage during DNA biosynthesis; (2) dimethylation of histone...
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Structural, magnetic and spectral properties of tetrahedral cobalt(II) silanethiolates: a variety of structures and manifestation of field-induced slow magnetic relaxation
PublicationBlue crystals of five heteroleptic cobalt(II) silanethiolates 1–5 have been obtained by the reaction of [Co{SSi (tBuO)3}2(NH3)]2 with aminopyridines and aminomethylpyridines at an appropriate molar ratio and their structural, spectral, thermal and magnetic properties have been established and described. All complexes 1–5 contain Co(II) ions in a tetrahedral CoN2S2 environment formed by (tBuO)3SiS− residues and pyridines and present...
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Effective Equations for the Optimum Seismic Gap Preventing Earthquake-Induced Pounding between Adjacent Buildings Founded on Different Soil Types
PublicationThe best approach to avoid collisions between adjacent structures during earthquakes is to provide sufficient spacing between them. However, the existing formulas for calculating the optimum seismic gap preventing pounding were found to provide inaccurate results upon the consideration of different soil types. The aim of this paper is to propose new equations for the evaluation of the sufficient in-between separation gap for buildings...
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Imidazoacridinone C-1311 induces both autophagy and senescence in human lung cancer A549 cells
PublicationNiedrobnokomórkowy rak płuc (ang. NSCLC, non-small cell lung cancer), stanowiący blisko 80-87% wszystkich przypadków, jest najczęściej występującą formą raka płuc. Skuteczność dotychczas stosowanych chemoterapeutyków w stosunku do tej formy raka jest bardzo ograniczona dlatego poszukuje się nowych związków o lepszych właściwościach leczniczych. Imidazoakrydon C-1311 wykazuje wysoką aktywność cytotoksyczną wobec komórek niedrobnokomórkowego...
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Antitumor 1-nitroacridine derivative C-1748 induces significant apoptosis in pancreatic cancer cells.
PublicationPancreatic cancer is the fifth leading cause of cancer death and has the lowest survival rate of any solid cancer in the industrial countries. The poor prognosis of pancreatic cancer results from its tendency for late presentation, aggressive invasion, early metastasis, and resistance to chemotherapy. Gemcitabine still remains the best chemotherapeutic agent available for the treatment of advanced pancreatic cancer. However, gemcitabine...
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Excessive amount of lactose in the diet of two-week-old calves induces urinary protein changes
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Relationship among the Change of Direction Ability, Sprinting, Jumping Performance, Aerobic Power and Anaerobic Speed Reserve: A Cross-Sectional Study in Elite 3x3 Basketball Players
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SIGNIFICANT GUIDELINE FOR THE DAMAGE INDICES APPLIED TO REINFORCED CONCRETE STRUCTURES
PublicationIn this paper, based on a deep overview and literature study, the different formulas proposed for damage indices (DIs) applied to reinforced concrete structures under monotonic or cyclic loading are classified and presented. The DIs are applied to quantify the damages to structures, ranging from zero to one. Normally, they are applied to make a decision for repairing or demolition of the structures in the post-earthquake phases. Keywords:...
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Fixed point indices of iterated smooth maps in arbitrary dimension
PublicationWe give a complete description of possible sequences ofindices of iterations of f at an isolated fixed point, answering inaffirmative the Chow, Mallet-Paret and Yorke conjecture posed in[S.N. Chow, J. Mallet-Parret, J.A. Yorke, A periodic point index whichis a bifurcation invariant, in: Geometric Dynamics, Rio de Janeiro,1981, in: Lecture Notes in Math., vol. 1007, Springer, Berlin, 1983,pp. 109-131].
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High-speed binary-to-residue converter with the reduced input layer
Publicationprzedstawiono architekturę szybkiego konwertera z systemu binarnego do systemu resztowego dla modułów 5-bitowych. Algorytm konwersji oparty jest na dodawaniu binarnym reszt potęg liczby 2 obliczonych modulo m i redukcji modulo m sumy dla poszczególnych modułów bazy systemu resztowego. Warstwa wejciowa konwertera jest redukowana poprzez wykorzystanie wspólnych elementów układu dla odpowiednio zestawionych par modułów.
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Hydrogen evolution on the reduced TiO2 under simulated solar lamp
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Synthesis, dispersion, and cytocompatibility of graphene oxide and reduced graphene oxide
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THE DETERMINANTS OF ENTERPRISE PROFI TABILITY DURING REDUCED ECONOMIC ACTIVITY
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Reduced order models in computational electromagnetics (in memory of Ruediger Vahldieck)
PublicationThis paper reviews research of Ruediger Vahldieck's group and the group at the Gdansk University of Technology in the area of model order reduction techniques for accelerating full-wave simulations. The applications of reduced order models to filter design as well as of local and nested(multilevel) macromodels for solving 3D wave equations and wave-guiding problems using finite difference and finite element methods are discussed.
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IFF/SSR rectangular patch antenna with reduced transversal size
PublicationW artykule przedstawiono antenę mikropaskową dla systemów IFF/SSR, zasilaną poprzez szczelinę typu H. Zastosowanie tego typu szczeliny pozwoliło na 36-procentową redukcję wymiaru poprzcznego anteny,co jest szczególnie istotne ze względu na potencjalne zastosowanie anteny w szykach.Pomierzone parametry eektryczne anteny to: VSWR < 1.5; stosunek polaryzacji ortogonalnej do właściwej < 30 dB w obu płaszczyznach;zysk > 7 dBi.
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GlyCulator2: an update on a web application for calculation of glycemic variability indices
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The pressure–strain work indices in response to isometric handgrip exercise
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Reduced graphene oxide and inorganic nanoparticles composites – synthesis and characterization
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Efficient bounds on quantum-communication rates via their reduced variants
PublicationWe investigate one-way communication scenarios where Bob operating on his component can transfer some subsystem to the environment. We define reduced versions of quantum-communication rates and, further, prove upper bounds on a one-way quantum secret key, distillable entanglement, and quantum-channel capacity by means of their reduced versions. It is shown that in some cases they drastically improve their estimation.
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Tailoring properties of reduced graphene oxide by oxygen plasma treatment
PublicationWe report an easily controllable, eco-friendly method for tailoring the properties of reduced graphene oxide (rGO) by means of oxygen plasma. The effect of oxygen plasma treatment time (1, 5 and 10 minutes) on the surface properties of rGO was evaluated. Physicochemical characterization using microscopic, spectroscopic and thermal techniques was performed. The results revealed that different oxygen-containing groups (e.g. carboxyl,...
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The properties of reduced Bi-Ge-O glasses for thermoelectric devices
PublicationThe bismuth-germanate glasses have been investigated to examine their applicability for thermoelectric devices. In order to increase their electrical conductivity, the 25Bi2O3–75GeO2 glass samples have been reduced at 340-380°C for 10 hours in hydrogen. It has been shown that such heat treatment in H2 leads to the reduction of metal ions Bi3+ and Ge4+ into neutral atoms and the formation of metal grains both in an amorphous glass...
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The properties of reduced Ge-Sb-O glasses for thermoelectric devices
PublicationThe structural and electrical properties of germanium-antimonate glasses after heat treatment in hydrogen have been determined. In the case of 50GeO2-50Sb2O3 glass reduced at 340°C even for less than 1 hour a continuous layer of antimony granules is formed and its electrical properties determine the surface conductivity of the reduced sample. The bulk electrical conductivity at 100°C of this sample was determined as 1000 Scm-1...
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Indices of interations and periodic points of simplical maps of smooth type
PublicationW pracy dowodzi się symplicjalnego odpowiednika twierdzenia Chowa, Mallet-Paret i Yorke´a. Otrzymany wynik służy do badania punktów periodycznych odwzorowań symplicjalnych gładkiego typu.
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Dimensionality-Reduced Antenna Modeling with Stochastically Established Constrained Domain
PublicationOver the recent years, surrogate modeling methods have become increasingly widespread in the design of contemporary antenna systems. On the one hand, it is associated with a growing awareness of numerical optimization, instrumental in achieving high-performance structures. On the other hand, considerable computational expenses incurred by massive full-wave electromagnetic (EM) analyses, routinely employed as a major design tool,...
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Gas-phase quasi-degeneracy of zwitterionic and canonical tautomers of glycine and proline induced by the presence of the MAlF4(M = Li, Na, K) salts
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Bisphenol A exposure and healing effects of Adiantum capillus-veneris L. plant extract (APE) in bisphenol A-induced reproductive toxicity in albino rats
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Biochar-induced immobilization and transformation of silver-nanoparticles affect growth, intracellular-radicles generation and nutrients assimilation by reducing oxidative stress in maize
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Wave-induced stress and breaking of sea ice in a coupled hydrodynamic&#8211;discrete-element wave&#8211;ice model
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Wave-induced stress and breaking of sea ice in a coupled hydrodynamic&#8211;discrete-element wave&#8211;ice model
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Wave-induced stress and breaking of sea ice in a coupled hydrodynamic&#8211;discrete-element wave&#8211;ice model
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A population of human brain cells expressing phenotypic markers of more than one lineage can be induced in vitro to differentiate into mesenchymal cells
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Polyvalent Mechanical Bacterial Lysate Administration Improves the Clinical Course of Grass Pollen–Induced Allergic Rhinitis in Children: A Randomized Controlled Trial
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Improvement of derivatized amino acid detection sensitivity in micellar electrokinetic capillary chromatography by means of acid-induced pH-mediated stacking technique
PublicationDerivatization is a frequently used sample prepara-tion procedure applicable to the enhancement of analyte de-tection sensitivity. Amino acids mostly require derivatization prior to electrophoretic or chromatographic analysis, especial-ly if spectrophotometric detection is used. This study presents an on-line preconcentration technique for derivatized amino acids. The sensitivity of the method was improved by the utilization of...
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CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells
PublicationWe examine whether CYP3A4 overexpression influences the rate and pattern of antitumor imidazoacridinone C-1311 metabolism, in relation to the impact of this overexpression on cell cycle progression and final cellular response of CHO cells following C-1311 treatment. Methods: Three CHO cell lines: CHO-WT, wild type, CHO-HR, overexpressing cytochrome P450 reductase (CPR) and CHO-HR-3A4, coexpressing CPR and CYP3A4 were applied....
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Water vapor induced self-assembly of islands/honeycomb structure by secondary phase separation in polystyrene solution with bimodal molecular weight distribution
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Functional Polymorphism in the Interleukin 6 (IL6) Gene with Respect to Depression Induced in the Course of Interferon-α and Ribavirin Treatment in Chronic Hepatitis Patients
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Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats
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Comparative study of donor-induced quantum dots in Si nano-channels by single-electron transport characterization and Kelvin probe force microscopy
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A simplified numerical approach to non-radiation induced high-temperature signals in thermoluminescence. GlowVIEW – a useful tool for a multiple glow-curve analysis
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Dependence between Ionic Liquid Structure and Mechanism of Visible-Light-Induced Activity of TiO2 Obtained by Ionic-Liquid-Assisted Solvothermal Synthesis
PublicationBecause of the tremendous structural diversityof ionic liquids (ILs), simple transfer of observations performed for one IL used for IL-TiO2 preparation on different samples is not possible. Therefore, four ionic liquids, all containing distinct nitrogen-bearing organic cations (pyridinium, pyrrolidinium, ammonium, imidazolium), were used for the first time for the preparation of IL-TiO2 composites. The role of the individual IL...
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Inner-shell fragmentation of molecules into neutral fragments in high-Rydberg states induced by soft X-ray excitation with pulsed-field ionization
PublicationIn the present communication, we will show the results of measurements probing the production of neutral high-Rydberg fragments at the K edges of the molecules containing oxygen and nitrogen atoms. The experiments were performed at the Gas Phase beamline of the Elettra synchrotron radiation laboratory (Trieste, Italy), exploiting a combined soft X-ray excitation with pulsed-field ionization and ion time-of-flight (TOF) spectrometry...
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AN OVERVIEW OF HEAT TRANSFER ENHANCEMENT BASED UPON NANOPARTICLES INFLUENCED BY INDUCED MAGNETIC FIELD WITH SLIP CONDITION VIA FINITE ELEMENT STRATEGY
PublicationThe mathematical model of heat generation and dissipation during thermal energy transmission employing nanoparticles in a Newtonian medium is investigated. Dimensionless boundary layer equations with correlations for titanium dioxide, copper oxide, and aluminium oxide are solved by the finite element method. Parameters are varied to analyze their impact on the flow fields. Various numerical experiments are performed consecutively...
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Thermal cooling process by nanofluid flowing near stagnating point of expanding surface under induced magnetism force: A computational case study
PublicationThis paper is dedicated to the exam of entropy age and research of the effect of mixing nanosolid additives over an extending sheet. In this review, Newtonian nanofluid version turned into researched at the actuated appealing field, heat radiation and variable heat conductivity results. With becoming modifications, the proven PDEs are moved into popular differential situations and paintings mathematically making use of a specific...
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c-Myc Protein Level Affected by Unsymmetrical Bisacridines Influences Apoptosis and Senescence Induced in HCT116 Colorectal and H460 Lung Cancer Cells
PublicationUnsymmetrical bisacridines (UAs) are highly active antitumor compounds. They contain in their structure the drugs previously synthesized in our Department: C-1311 and C-1748. UAs exhibit different properties than their monomer components. They do not intercalate to dsDNA but stabilize the G-quadruplex structures, particularly those of the MYC and KRAS genes. Since MYC and KRAS are often mutated and constitutively expressed in cancer...
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Inter-individual diversity and intra-individual stability of amphetamine-induced sensitization of frequency-modulated 50-kHz vocalization in Sprague–Dawley rats
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Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice
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One- and two-photon induced fluorescence of Pacific Blue-labeled human serum albumine deposited on different core size silver colloids
PublicationPublikacja opisuje jedno i dwufotonowo indukowaną Fluorescencje znakowanej barwnikiem ''Pacific Blue'' ludzkiej albuminy osadzonej na srebrnych koloidach różnych rozmiarów