Search results for: CB1 RECEPTOR
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Methodology of Selecting the Optimal Receptor to Create an Electrochemical Immunosensor for Equine Arteritis Virus Protein Detection
PublicationThe study reports a methodology of selecting the optimal receptor to create an electrochemical immunosensor for equine arteritis virus (EAV) protein detection. The detection was based on antigen recognition by antibodies immobilized on gold electrodes. Modification steps were controlled by electrochemical impedance spectroscopy and cyclic voltammetry measurements. In order to obtain the impedance immunosensor with the best parameters,...
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Estrogen receptors 1 and 2 genotypes and age at menarche in idiopathic scoliosis
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Molecular Dynamics Study of the Internal Water Molecules in Vasopressin and Oxytocin Receptors
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Zastosowanie metodologii CBR do wyznaczania optymalnego zaopatrzenia punktu sprzedaży detalicznej.
PublicationW artykule rozważane jest zagadnienie optymalnego doboru asortymentu towarów dla punktu sprzedaży detalicznej. Scharakteryzowano podstawowe czynniki ekonomiczne determinizujące przychody i koszty detalisty. Dla rozpatrywanego problemu zbudowano model matematyczny w formie zadania programowania liniowego, w którym poszukiwane jest maksimum zysku detalisty z uwzględnieniem najistotniejszych ograniczeń w handlu: ilości dostępnego...
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Ryzykowna recepta na zarządzanie ryzykiem
PublicationCzy zaawansowana metodologia wyznaczania i alokacji kapitału ekonomicznego w bankach, wsparta przez odpowiednie normy regulacyjne, stanowi panaceum na bolączki związane z systemowymi ryzykami sektora bankowego? Idealizowanie tej recepty jest dość ryzykowne. Kapitał ekonomiczny to ciekawe narzędzie, ma ono jednak swoje niedoskonałości i pułapki.
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Reception of GNSS Signals Under Jamming Conditions
PublicationThe article focuses on performance of Global Navigation Satellite System receivers in environment where intentional interference is present. First part is a general description of GNSS systems. Secondly, types of positioning service disturbances are specified. In the third part authors present a scheme of measurement stand which is used to evaluate the influence of interference on reception of navigation signals. Next, research...
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Docking is not enough: 17-trifluoromethylphenyl trinor PGF2α is only a very weak ligand of neurokinin-1 receptor
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Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor
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Phase 3 randomised study of avatrombopag, a novel thrombopoietin receptor agonist for the treatment of chronic immune thrombocytopenia
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Replication study of estrogen receptor 1 XbaI polymorphism in adolescent idiopathic scoliosis (AIS) Caucasian population
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Angiotensin receptor blockers and cancer – Relationship dismissed by VALUE data while waiting for EMA and FDA reports
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Ambulatory Blood Pressure Adds to Explaining Benefits of AT‐1 Receptor Blockade in the Treatment of Left Ventricular Hypertrophy
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Synthesis of Fentanyl Triazole Derivatives and their Affinity for Mu-Opioid and Sigma-1 Receptors
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Theoretical Study on Interactions of Bicyclic Vasopressin Analogues with Human Neurohypophyseal Hormone Receptors
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Expression of estrogen receptors, PELP1, and SRC in human spermatozoa and their associations with semen quality
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Neurohypophyseal Receptors-Ligands: Where We Are After the Landmark Rhodopsin Structure Determination
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Molecular Dynamics of Complexes of Atosiban with Neurohypophyseal Receptors in the Fully Hydrated Phospholipid Bilayer
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Fosfonowe pochodne kaliks[4]arenów jako receptory w środowisku wodnym
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CBR methodology application in an expert system for aided design ship's engine room automation
PublicationW artykule przedstawiono metody obliczania podobieństwa na podstawie przypadków, zastosowane w opracowanym systemie ekspertowym do wspomagania projektowania siłowni okrętowej. Do realizacji metody na przykładzie automatyki napędu głównego zastosowano oprogramowanie bazy danych i system ekspertowy. Uzyskane wyniki wyszukiwania w bazie danych statków podobnych zostały porównane i przeanalizowane. Do weryfikacji zastosowanych w bazie...
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Rola polimorfizmu i zróżnicowanej ekspresji genów cytochromu P450 w metabolizmie ksenobiotyków.
PublicationZdolność do metabolizmu ksenobiotyków przez cytochromy P450 (CYP) określona jest przez polimorfizm i poziom ekspresji genów tych białek. Najwięcej, 40 odmian polimorficznych o zróżnicowanej aktywności enzymatycznej, poznano dla CYP2D6, natomiast tylko dwie w przypadku CYP2C9, których obecność powoduje zahamowanie metabolizmu wielu leków. Z kolei polimorfizm genu CYP3A4 nie miał istotnego wpływu na aktywność metaboliczną jego produktu...
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Radiochemical Synthesis and Evaluation of Novel Radioconjugates of Neurokinin 1 Receptor Antagonist Aprepitant Dedicated for NK1R-Positive Tumors
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The Leaderless Bacteriocin Enterocin K1 Is Highly Potent against Enterococcus faecium: A Study on Structure, Target Spectrum and Receptor
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Effect of psoriasis activity and topical treatment on plasma epidermal growth factor (EGF) and its soluble receptor (sEGFR)
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XbaI and PvuII Polymorphisms of Estrogen Receptor 1 Gene in Females with Idiopathic Scoliosis: No Association with Occurrence or Clinical Form
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Methylation level of the regulatory regions of the estrogen receptor type 1 gene in paravertebral muscles of girls with idiopathic scoliosis
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Effect of psoriasis activity on epidermal growth factor (EGF) and the concentration of soluble EGF receptor in serum and plaque scales
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Methylation of Estrogen Receptor 1 Gene in the Paraspinal Muscles of Girls with Idiopathic Scoliosis and Its Association with Disease Severity
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N-Substituted piperazine derivatives as potential multitarget agents acting on histamine H3 receptor and cancer resistance proteins
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Nephrotic syndrome unfavorable course correlates with downregulation of podocyte vascular endothelial growth factor receptor (VEGFR)-2
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Vitamin D Receptor Gene Polymorphism and Vitamin D Status in Population of Patients with Cardiovascular Disease—A Preliminary Study
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New generation of analytical tests based on the assessment of enzymatic and nuclear receptor activity changes induced by environmental pollutants
PublicationAnalytical methods show great potential in biological tests. The analysis of biological response that results from environmental pollutant exposure allows: (i) prediction of the risk of toxic effects and (ii) provision of the background for the development of markers of the toxicants presence. Bioanalytical tests based on changes in enzymatic activity and nuclear receptor action provide extremely high specificity and sensitivity....
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Optimization of microstructure and properties of acceptor-doped barium cerate
PublicationThe presented research concerns acceptor doped barium cerate and the attempts of improvement of its production method that would allow obtaining the solid electrolyte characterized by the particular properties. The authors suggest combining two production methods, molten salt synthesis and self-combustion, in order to achieve the compound material that has some of the advantages of both of the initial methods. An impact of nickel...
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Water uptake analysis of acceptor-doped lanthanum orthoniobates
PublicationIn this work, lanthanum orthoniobates doped with either antimony, calcium, or both have been synthesized and studied. The water uptake of the investigated materials has been analyzed by means of thermogravimetric studies. The results show the difference between the thermodynamics of hydration between the lanthanum orthoniobate system and other proton conducting ceramics. The relation between the water uptake and effective acceptor...
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On residualities in the set of Markov operators on C1
PublicationDowodzi się, że zbiór operatorów Markowa na klasie Schattena 1, które są mieszające w normie, jest normowo gęsty, otwarty. Natomiast w topologii mocno operatorowej operatory Markowa mocno mieszające są zbiorem I kategorii.
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Current Writing-Text and Reception in Southern Africa
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Studies on Aryl-Substituted Phenylalanines: Synthesis, Activity, and Different Binding Modes at AMPA Receptors
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The use of Preston equation to determine material removal during lap-grinding with electroplated CBN tools
PublicationGrinding executed in a lapping configuration is an alternative finishing process benefiting from both grinding and free-abrasive machining, while minimizing the heat effect impact. Electroplated tools can be effectively used in different abrasive processes, including high-speed grinding, however, the assessment of machining performance over time is a key factor in their correct use to achieve satisfactory technological results....
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Synthesis, activity on NK-3 tachykinin receptor and conformational solution studies of scyliorhinin II analogs modified at position 16
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Does Porcine Oocytes Maturation in Vitro is Regulated by Genes Involved in Transforming Growth Factor Beta Receptor Signaling Pathway?
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Novel Potent Muscarinic Receptor Antagonists: Investigation on the Nature of Lipophilic Substituents in the 5- and/or 6-Positions of the 1,4-Dioxane Nucleus
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Molecular dynamics study of 4-OH-phenylacetyl- D -Y(Me)FQNRPR-NH 2 selectivity to V1a receptor
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Polymorphism in the chemokine receptor 7 gene (CCR7) is associated with previous myocardial infarction in patients undergoing elective coronary angiography
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π-Conjugated Donor-acceptor Polyelectrolytes: Toward Artificial Photosynthesis
PublicationGreat advances have been made in the development of conjugated polyelectrolytes (CPEs), which provide tunable properties including water solubility and processability, main-chain exciton and charge transport, variable energy light absorption and fluorescence, non-covalent interactions, and formation of tertiary structures via self-assembly.[1] These characteristics allow CPEs to be considered for use in various optoelectronic applications,...
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Synthesis of acceptor-doped Ba-Ce-Zr-O perovskites
PublicationPublikacja przedstawia wyniki badań stukturalnych i elektrycznych domieszkowanego akceptorow cerianu baru.
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The function of the sculpture in public space and its reception occupants of the city
PublicationSculpture has been with people for thousands of years. Its destiny, subject and scale have changed over the centuries. Public art, along with sculpture, began to appear in a new form (not only to commemorate important figures and events) only in the 1960s. This paper aims to answer what functions are currently performed by the sculptures located in a public space and how they are perceived by the inhabitants of the city.
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Strong mixing Markov semigroups on C1 are meager
PublicationDowodzi się, że zbiór tych półgrup operatorów Markowa na klasie Schattena C1, dla których w mocnej topologii operatorowej T(t) jest zbieżne do operatora Markowa Q, gdzie Q jest 1-wymiarową projekcją, jest zbiorem rzadkim w zbiorze wszystkich półgrup Markowa.
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Similarities and differences in affinity and binding modes of tricyclic pyrimido- and pyrazinoxanthines at human and rat adenosine receptors
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Both activating and inhibitory Fc gamma receptors mediate rituximab-induced trogocytosis of CD20 in mice
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Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management
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Expression and cellular distribution of estrogen and progesterone receptors and the real-time proliferation of porcine cumulus cells
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