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Search results for: mtDNA genome
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Smart Virtual Bass Synthesis Algorithm Based on Music Genre Classification
PublicationThe aim of this paper is to present a novel approach to the Virtual Bass Synthesis (VBS) algorithms applied to portable computers. The proposed algorithm employed automatic music genre recognition to determine the optimum parameters for the synthesis of additional frequencies. The synthesis was carried out using the non-linear device (NLD) and phase vocoder (PV) methods depending on the music excerpt genre. Classification of musical...
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Bass Enhancement Settings in Portable Devices Based on Music Genre Recognition
PublicationThe paper presents a novel approach to the Virtual Bass Synthesis (VBS) applied to mobile devices, called Smart VBS (SVBS). The proposed algorithm uses an intelligent, rule-based setting of bass synthesis parameters adjusted to the particular music genre. Harmonic generation is based on a nonlinear device (NLD) method with the intelligent controlling system adapting to the recognized music genre. To automatically classify music...
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Intelligent equalizer solution employing music genre and the room characteristics analysis
PublicationThe paper presents an intelligent equalizer solution based on room acoustic conditions and music genre analysis. A series of acoustic characteristic measurements are performed for checking the concept proposed. White noise (reference signal) and audio excerpts belonging to six music genres are utilized as excitation signals in measurements. This results in registration of frequency responses of rooms and reverberation times. Signals...
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An examination of an Antarctic soil metagenomic-derivate putative methylthioadenosine phosphorylase gene as a novel reporter gene for promoter trapping
PublicationThe rsfp gene was discovered during examination ofan Antarctic soil-derived metagenome library and encodesa bacterial methylthioadenosine phosphorylase (GenBank accession number GQ202582). In a previous study, we found that E. coli colonies expressing the rsfp gene reveal strong pink fluorescence after exposure to UV light when grown on culture medium supplemented with rhodamine B (Cieśliński et al., 2009). In contrast to that,...
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Evolving gene regulatory networks controlling foraging strategies of prey and predators in an artificial ecosystem
PublicationCo-evolution of predators and prey is an example of an evolutionary arms race, leading in nature to selective pressures in positive feedback. We introduce here an artificial life ecosystem in which such positive feedback can emerge. This ecosystem consists of a 2-dimensional liquid environment and animats controlled by evolving artificial gene regulatory networks encoded in linear genomes. The genes in the genome encode chemical...
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Stable nanoconjugates of transferrin with alloyed quaternary nanocrystals Ag–In–Zn–S as a biological entity for tumor recognition
PublicationOne way to limit the negative effects of anti-tumor drugs on healthy cells is targeted therapy employing functionalized drug carriers. Here we present a biocompatible and stable nanoconjugate of transferrin anchored to Ag-In-Zn-S quantum dots modified with 11-mercaptoundecanoic acid (Tf-QD) as a drug carrier versus typical anticancer drug, doxorubicin. Detailed investigations of Tf-QD nanoconjugates without and with doxorubicin...
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Wiktor Sieklicki dr inż.
PeopleMechanical Engineer degree in Automatics and Robotics achieved in 2006 from Mechanical Faculty of Gdansk University of Technology, Mechanics and Strength of the Materials Department (thesis topic: "Micro electro-mechanical devices for laparoscopy"). Thesis written during the exchange program with Genova University, Italy. PhD in Mechatronics finished in 2010 from Mechanical Faculty of Gdansk University of Technology, Mechanics...
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A concept of Signal Equalization Method Based on Music Genre and the Listener's Room Characteristics
PublicationA research study that investigates the influence of the room acoustics environment on the frequency characteristic of the audio signal playback is presented. First, a novel spectral equalization method of the room acoustic conditions is introduced. On the basis of the frequency response of the room, a system for room acoustics compensation based on eight-band equalizer is proposed. The system settings depend on music genre. In...
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Osteoprotegerin gene polymorphism in diabetic Charcot neuroarthropathy
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Genistein modulates gene activity in psoriatic patients
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Modelling gene expression of a self-regulating protein
PublicationWe analyze a model of gene transcription and protein synthesis. We take into account the number of sites on the protein’s promoter at which the protein’s dimers can bind blocking transcription of protein mRNA.
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ANALYSIS OF THE p53 PROTEIN GENE EXPRESSION MODEL
PublicationWe study the asymptotic behaviour of the solutions of the p53-Mdm2 model proposed by Monk (2003). The p53 gene is crucial for cellular inhibition of the angiogenesis process, while Mdm2 is a negative regulator of the p53 tumor-suppressor. We investigate the stability of the positive steady state and perform some numerical experiments.
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A Simple Model of Linkage Disequilibrium and Genetic Drift in Human Genomic SNPs: Importance of Demography and SNP Age
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Genomic and Functional Characterization of the Unusual pLOCK 0919 Plasmid Harboring thespaCBAPili Cluster inLactobacillus caseiLOCK 0919
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Properties of Ginkgo biloba L.: Antioxidant Characterization, Antimicrobial Activities, and Genomic MicroRNA Based Marker Fingerprints
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When migrant men become more involved in household and childcare duties – the case of Polish migrants in Norway
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Comprehensive phenomic and genomic studies of the species, Pectobacterium cacticida and proposal for reclassification as Alcorniella cacticida comb. nov
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Genomic and Functional Characterization of Environmental Strains of SDS-Degrading Pseudomonas spp., Providing a Source of New Sulfatases
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Uprzednie uzgodnienia cenowe jako narzędzie w sprawach porozumień w zakresie ustalania cen transakcyjnych
PublicationW dobie nasilonych procesów globalizacji, problem unikania opodatkowania poprzez lokowanie dochodów w krajach o niskim opodatkowaniu staje się coraz bardziej istotnym. Narzędziem ograniczenia sporów z organem podatkowym w zakresie cen stosowanych przez podmioty powiązane są ''uprzednie porozumienie cenowe''. Narzędzie to zostało po raz pierwszy wprowadzone do polskiego prawodastwa podatkowego od 1.01.2006 r.
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Wielkoskalowe formy handlu we współczesnym mieście – szansa czy zagrożenie? Studium przypadku wrocławskiej „Renomy”
PublicationArtykuł związany jest z kwestią kształtowania struktur handlu wielkoskalowego we współczesnych miastach. Zagadnienie to zaprezentowano na bazie transformacji historycznego budynku wrocławskiej Renomy.
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Fenomen przemocy w doktrynach prawnych. Tendencje legislacyjne dotyczące sprawcy i osoby doznającej przemocy
PublicationPrzemoc, aczkolwiek różnie postrzegana, stanowi przedmiot zainteresowania wielu dziedzin prawa. Pod różnymi postaciami reguluje je prawo karne, szeroko rozumiane prawo cywilne, ale także prawo pracy. Z uwagi na wieloaspektowość omawianego zjawiska niemożliwe jest przedstawienie wszystkich odsłon, a jedynie zasygnalizowanie tych obszarów, w których ono występuje i w których odgrywa szczególną rolę. Do przeprowadzenia analizy wykorzystano...
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Bulletin de la Société d'Egyptologie de Genève
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Gene Regulation and Systems Biology
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Human Gene Therapy Methods
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Journal of RNAi and Gene Silencing
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Evolution of artificial single-cell organisms foraging for resources in a 3-dimensional environment
PublicationForaging for resources is a simple cognitive task that even one-celled biological organisms can ac- complish. We present an Artificial Life system in which artificial unicellular organisms (animats) forage for food in a 3-dimensional simulated liquid environment. The movement of animats is controlled by evolving artificial gene regulatory networks encoded in linear genomes. When an animat consumes enough food, it produces offspring...
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Meta Gene
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Analiza poziomu hałasu generowanego przez samochód osobowy oparta na modelu VENOM.
PublicationPrzedstawiono w dużym zarysie model VENOM, opisujący hałas samochodu osobowego, opracowany w Katedrze Pojazdów i Maszyn Roboczych Politechniki Gdańskiej przy współpracy ze szwedzkim instytutem VTI. Zaprezentowano wyniki dotyczące generowanego hałasu przez cztery wybrane pojazdy dla różnych warunków ruchu, uzyskane na drodze symulacji. W dalszej kolejności poddano szczegółowej analizie poziomy hałasu generowanego przez pojazdy podczas...
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Genre-Based Music Language Modeling with Latent Hierarchical Pitman-Yor Process Allocation
PublicationIn this work we present a new Bayesian topic model: latent hierarchical Pitman-Yor process allocation (LHPYA), which uses hierarchical Pitman-Yor pr ocess priors for both word and topic distributions, and generalizes a few of the existing topic models, including the latent Dirichlet allocation (LDA), the bi- gram topic model and the hierarchical Pitman-Yor topic model. Using such priors allows for integration of -grams with a topic...
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A Study on Influence of Normalization Methods on Music Genre Classification Results Employing kNN Algorithms
PublicationThis paper presents a comparison of different normalization methods applied to the set of feature vectors of music pieces. Test results show the influence of min-nlax and Zero-Mean normalization methods, employing different distance functions (Euclidean, Manhattan, Chebyshev, Minkowski) as a pre-processing for genre classification, on k-Nearest Neighbor (kNN) algorithm classification results.
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Genre-Based Music Language Modeling with Latent Hierarchical Pitman-Yor Process Allocation
PublicationIn this work we present a new Bayesian topic model: latent hierarchical Pitman-Yor process allocation (LHPYA), which uses hierarchical Pitman-Yor pr ocess priors for both word and topic distributions, and generalizes a few of the existing topic models, including the latent Dirichlet allocation (LDA), the bi- gram topic model and the hierarchical Pitman-Yor topic model. Using such priors allows for integration of -grams with a topic model,...
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Joint Genomic and Proteomic Analysis Identifies Meta-Trait Characteristics of Virulent and Non-virulent Staphylococcus aureus Strains
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Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine
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Rush to become "globally relevant"- culture based development as a significant factor towards sustainable urbanization (Gdansk Case)
PublicationThe paper shows possibilities and barriers as well as attempts to implement culture based development in Gdansk. It can play a significant role in preventing uncontrolled suburban residential development and further spatial polarization of the city.
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Circadian Gene Polymorphisms Associated with Breast Cancer Susceptibility
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Phenotypic consequences of the LYS4 gene disruption in Candida albicans
PublicationThe main scientific purpose of our studies was to verify the hypothesis that homoaconitase (HA) from Candida albicans, an enzyme catalyzing a second step of the α-aminoadipate pathway (AAP) of L-Lys biosynthesis may become a new target for antifungal chemotherapy. Previous studies indicated that the A. fumigatus mutant lacking the functional lysF gene, encoding HA, exhibited attenuated virulence in a low-dose mouse infection model...
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Gene-based identification of bacterial colonies with an electric chip
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Gene copy numbers of HER family in breast cancer
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Estrogen Receptor 2 Gene Polymorphism in Idiopathic Scoliosis
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CHD7 gene polymorphisms in female patients with idiopathic scoliosis
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Cognitive decline in Huntington's disease expansion gene carriers
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Phenotypic consequences of LYS4 gene disruption in Candida albicans
PublicationA BLAST search of the Candida Genome Database with the Saccharomyces cerevisiae LYS4 sequence known to encode homoaconitase (HA) revealed ORFs 19.3846 and 19.11327. Both alleles of the LYS4 gene were sequentially disrupted in Candida albicans BWP17 cells using PCR-based methodology. The null lys4Δ mutant exhibited lysine auxotrophy in minimal medium but was able to grow in the presence of L-Lys and α-aminoadipate, an intermediate...
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Plasmids pMET2M1 and pMET15M1 with the SAT1 Flipper knockout cassette construction
Open Research DataThe goal of the study was to obtain plasmids containing the SAT1 Flipper knockout cassette along with upstream and downstream gene fragments (MET2, MET15) and to introduce a cleavage site for restriction enzymes into them.
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ArchBGal32cB 441Glu mutein gene analysis dataset
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Elgold: gold standard, multi-genre dataset for named entity recognition and linking
Open Research DataThe dataset contains 276 multi-genre texts with marked named entities, which are linked to corresponding Wikipedia articles if available. Each entity was manually verified by at least three people, which makes the dataset a high-quality gold standard for the evaluation of named entity recognition and linking algorithms.
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Cancer Familial Aggregation (CFA) and G446A polymorphism in ARLTS1 gene
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Reproducibility of Finding Enriched Gene Sets in Biological Data Analysis
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Ranking metrics in gene set enrichment analysis: do they matter?
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Newborn screening and gene therapy in SMA: Challenges related to vaccinations
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Vitamin D receptor gene polymorphisms in Alzheimer's disease patients
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