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Search results for: BLOK G2
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Increased cytotoxicity of an unusual DNA topoisomerase II inhibitor compound C-1305 toward HeLa cells with downregulated PARP-1 activity results from re-activation of the p53 pathway and modulation of mitotic checkpoints
PublicationOur previous studies have shown that murine fibroblast cells, in which PARP-1 gene was inactivated by gene disruption, are extremely sensitive to triazoloacridone compound C-1305, an inhibitor of DNA topoisomerase II with unusual properties. Here, we show that pharmacological inhibition of PARP-1 activity by its inhibitor compound NU1025, sensitizes human cervical carcinoma HeLa cells to compound C-1305 compared to treatment with...
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Molecular basis for the DNA damage induction and anticancer activity of asymmetrically substituted anthrapyridazone PDZ-7
Publicationnthrapyridazones, imino analogues of anthraquinone, constitute a family of compounds with remarkable anti-cancer activity. To date, over 20 derivatives were studied, of which most displayed nanomolar cytotoxicity towards broad spectrum of cancer cells, including breast, prostate and leukemic ones. BS-154, the most potent derivative, had IC50 values close to 1 nM, however, it was toxic in animal studies. Here, we characterize another...
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Sławomir Jerzy Ambroziak dr hab. inż.
PeopleSławomir J. Ambroziak was born in Poland, in 1982. He received the M.Sc., Ph.D. and D.Sc. degrees in radio communication from Gdańsk University of Technology (Gdańsk Tech), Poland, in 2008, 2013, and 2020 respectively. Since 2008 he is with the Department of Radiocommunication Systems and Networks of the Gdańsk Tech: 2008-2013 as Research Assistant, 2013-2020 as Assistant Professor, and since 2020 as Associate Professor. He is...
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II Ogólnopolski Turniej Tańca Sportowego
Events14.05.2022 r. w hali Centrum Sportu Akademickiego PG odbędzie się Grand Prix Polski Ekstraklasa oraz II Ogólnopolski Turniej Tańca Sportowego, pod patronatem prof. Krzysztofa Wildego.
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The increased level of cytochrome P450 isoenzyme CYP3A4 affects the cellular response in CHO cells upon antitumor imidazoacridinone C-1311 treatment
PublicationPochodna C-1311 to potencjalny związek przeciwnowotworowy, który dotarł do II fazy badań klinicznych. Związek ten ulega metabolicznej transformacji pod wpływem szczurzych i ludzkich białek mikrosomalnych. Wykazano, że białka cytochromu P450 odpowiadają za przemiany metaboliczne C-1311 jedynie w niewielkim stopniu. Z drugiej strony wykazano, że pochodna C-1311 jest inhibitorem białek cytochromu P450, zwłaszcza izoenzymu CYP1A2...
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Numerical Characterization of Thresholds for the Focusing 1d Nonlinear Schrödinger Equation
PublicationThe focusing nonlinear Schrödinger equation arises in various physical phenomena and it is therefore of interest to determine mathematical conditions on the initial data that guarantee whether the corresponding solution will blow up in finite time or exist globally in time. We focus on solutions to the mass‐supercritical nonlinear Schrödinger equation (1) in 1D case. In particular, we investigate numerical thresholds between blow...
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A Finite Element Approach for Wave Propagation in Elastic Solids
PublicationThis book focuses on wave propagation phenomena in elastic solids modelled by the use of the finite element method. Although the latter is a well-established and popular numerical tool used by engineers and researchers all around the word the process of modelling of wave propagation can still be a challenge. The book introduces a reader to the problem by presenting a historical background and offering a broad perspective on the...
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Sustainable Investing. Socio-Economic Impacts of Exchange-Traded Funds
PublicationSustainable Investing: Socio-Economic Impacts of Exchange-Traded Funds examines the social and economic effects of sustainable investing ETFs and their impacts on the global financial system. The book presents the key issues with regard to sustainable investing, discussing exchange-traded funds mechanisms and categories in comparison to competing investment funds. The book outlines the theoretical determinants of ETF markets development...
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Determination of flow properties of a serial connection of a directional control valve with (C=5.7, b=0.32) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.1, b=0.14) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=7.3, b=0.49) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.8, b=0.25) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=5.5, b=0.37) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=6.4, b=0.45) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=6.2, b=0.38) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.4, b=0.26) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=3.3, b=0.40) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a directional control valve with (C=2.0, b=0.11) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a directional control valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> DCV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=4.4, b=0.42) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Determination of flow properties of a serial connection of a pressure relief valve with (C=5.3, b=0.38) and a air blow gun from changes in air pressure in a tank being emptied
Open Research DataThe aim of the study was to determine the flow properties of serial connection of pneumatic components.The experiments were to measure the pressure changes in a being emptied tank for a pressure relief valve and a air blow gun (with nozzle removed) arranged in-line. Three test configurations were used: (1) being emptied tank -> PRV -> ambient...
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Addressing the Weaknesses of Multi-Criteria Decision-Making Methods using Python
PublicationThe book aims to draw attention to the weaknesses in Multi-Criteria Decision-Making (MCDM) methods and provide insights to improve the decision-making process. By addressing these weaknesses, it seeks to enhance the accuracy and effectiveness of MCDM methods in selecting the best alternatives in various fields. The book covers popular MCDM methods such as TOPSIS, ELECTRE, VIKOR, and PROMETHEE. It compares traditional methods with...
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Principles of Corporate Governance
PublicationThe book places ownership at the centre of all relevant choices that the conpany makes: in particular it adresses the problem of governance from the perspective of owenership. The second part of the book analyzes in a number of coutries economic systens, caputakism models, dfferent economic cultures, and their role in defining the type of corporate governance that has emerged
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The accretion of the new ice layer on the surface of hexagonal ice crystal and the influence of the local electric field on this process
PublicationThe process of creation of a new layer of ice on the basal plane and on the prism plane of a hexagonal ice crystal is analyzed. It is demonstrated that the ordering of water molecules in the already existing crystal affects the freezing. On the basal plane, when the orientations of water molecules in the ice block are random, the arrangement of the new layer in a cubic manner is observed more frequently — approximately 1.7 times...
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Jesień w Bibliotece PG
PublicationArtykuł jest podsumowaniem licznych aktywności podjętych przez Bibliotekę PG w okresie jesiennym 2023 r., ukierunkowanych na czytelnictwo, jak i wynikających z naukowo-edukacyjno-kulturalnego charakteru tej jednostki. Z zestawienia zaprezentowanych wydarzeń wyłania się obraz Biblioteki PG jako miejsca...
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Marcin Jaskólski dr inż.
PeopleStudiował na kierunku Elektrotechnika na Wydziale Elektrotechniki i Automatyki Politechniki Gdańskiej. W roku 2002 obronił pracę magisterską pt. "Analiza zastosowań technologii ogniw paliwowych w energetyce", realizowaną pod opieką dr. inż. Andrzeja Augusiaka z Katedry Elektroenergetyki. W tym samym rozpoczął realizację pracy doktorskiej z zakresu modelowania rozwoju regionalnych systemów energetycznych w programie MARKAL i wykorzystania...
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Projektowanie bloków funkcjonalnych kanałów cyfrowych - 2022/2023
e-Learning Courses -
Zaawansowane przetwarzanie sygnałów telekomunikacji cyfrowej - Laboratorium 2022/2023
e-Learning CoursesKurs wspomagający do laboratorium z Zaawansowanego przetwarzania sygnałów telekomunikacji cyfrowej prowadzonego dla II stopnia kierunku Elektronika i telekomunikacja (specjalność: Systemy i sieci teleinformacyjne).
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Zaawansowane przetwarzanie sygnałów telekomunikacji cyfrowej - Laboratorium 2021/2022
e-Learning CoursesKurs wspomagający do laboratorium z Zaawansowanego przetwarzania sygnałów telekomunikacji cyfrowej prowadzonego dla II stopnia kierunku Elektronika i telekomunikacja (specjalność: Systemy i sieci teleinformacyjne).
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Zaawansowane przetwarzanie sygnałów telekomunikacji cyfrowej - Wykład 2022/2023
e-Learning CoursesElektronika i Telekomunikacja, studia magisterskie sem. 2
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Cache service for maps presentation in distributed information data exchange system
PublicationThe paper presents the proposition of caches implementation for map presentation in distributed information data exchange system. The concept of cache service is described in the context of distributed information data exchange system elements which control and present on maps positions and other identification data of vessels and other suspicious objects on the territorial sea, sea-coast and the internal sea-waters. The proposed...
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Performance measurements and optimization of visualization of routes traveled in the distributed dispatcher and teleinformation system for visualization of multimedia data for the Border Guard
PublicationMonitoring of country maritime border is an important task of the Border Guard. This activity can be enhanced with the use of the technology enabling gathering information from distributed sources, processing of that information and its visualization. The system presented in the paper is an advancement of the previously developed distributed map data exchange system. The added functionality allows to supplement the map data with...
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MAPSERVER – INFORMATION FLOW MANAGEMENT SOFTWARE FOR THE BORDER GUARD DISTRIBUTED DATA EXCHANGE SYSTEM
PublicationIn this paper the architecture of the software designed for management of position and identification data of floating and flying objects in Maritime areas controlled by Polish Border Guard is presented. The software was designed for managing information stored in a distributed system with two variants of the software, one for a mobile device installed on a vessel, an airplane or a car and second for a central server. The details...
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The central server of the Border Guard's distributed multimedia system for monitoring and visualisation of ongoing and archival events
PublicationThe paper presents the architecture and functionalities of the central server (CENTER) of the distributed system for the Polish Border Guard (BG) for monitoring maritime areas. The overall system has been extended to incorporate, apart from map data, also different multimedia elements such as video from cameras or audio from telephone connections operated by BG units. This requires new system elements: Archive Servers for storing...
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Obsługa danych radarowych w rozproszonym systemie komunikacji i nadzoru projektu STRADAR
PublicationJednym z zadań rozszerzenia projektu STRADAR jest zrealizowanie zaawansowanego przetwarzania (reduplikacja, multifuzja) i prezentacji danych pochodzących z urządzeń radarowych znajdujących się pod kontrolą Morskiego Oddziału Straży Granicznej. W artykule przedstawiono założenia dla realizacji oprogramowania fuzji danych radarowych w serwerach archiwizacji, ogólną strukturę podsystemu obsługi danych radarowych, moduły wejściowe...
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The conducted EMI in DC-DC converters
PublicationThis book presents the phenomena of conducted electromagnetic interference (EMI) generation in DC-DC converters. The measurement and simulation are used to analyze the impact of the most important parameters on the character, level and propagation path of interference. In this book, the analysis of the interference generation and propagation is presented on the example of three basic converters. The wide banded behavior of all...
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Social Media in the Fashion Industry. Fundamentals, Strategy and Research Methods
PublicationThis book introduces social network fundamentals in the fashion domain. It addresses the creation of social media marketing plans, highlighting strategic approaches that allow fashion brands to differentiate themselves in the ephemeral and challenging fashion context. Through a variety of academic and professional sources and by sharing the results of their own research, the authors present research methodologies, including netnography,...
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Modeling and control of a redundantly actuated variable mass 3RRR planar manipulator controlled by a model-based feedforward and a model-based-proportional-derivative feedforward–feedback controller
PublicationIn the paper, dynamics of a complex mechatronics system is considered. A redundantly actuated planar manipulator is the base of the mechanical part of it. It is a 3RRR 1 platform based parallel manipulator. To control its trajectory, a model-based feedforward controller is employed. Three aspects are fundamental in the presented investigations. The first focus is on development of an accurate numerical model used to solve the inverse...
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Antitumor imidazoacridinone derivative C-1311 induces cell cycle arrest and cellular senescence-like phenotypic changes in human non-small lung A549 cancer cells
PublicationPrzeprowadzone badania miały na celu zbadanie rodzaju odpowiedzi komórkowej indukowanej przez pochodną C1311 w komórkach ludzkiego, niedrobnokomórkowego raka płuc A549, wyselekcjonowanych do badań ze względu na wysoką wrażliwość na działanie pochodnej C-1311. Wszystkie eksperymenty przeprowadzone zostały przy stężeniu hamującym proliferację komórek nowotworowych w 80%. Badania z wykorzystaniem techniki cytometrii przepływowej oraz...
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Commercially produced and modified starches
PublicationThis book presents some fascinating phenomena associated with the remarkable features of high performance polymers and also provides an update on applications of modern polymers. It offers new research on structure–property relationships, synthesis and purification, and potential applications of high performance polymers. The collection of topics in this book reflects the diversity of recent advances in modern polymers with a broad...
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Structure of the register of immovable monuments by date of individual objects – comparison of 2017 and 2024
Open Research DataThe register of monuments is the primary form of monument protection. The register for monuments in the voivodeship is kept by the voivodeship conservator of monuments in the form of separate books for immovable (book A), movable (book B), and archaeological (book C) monuments. Entries in the register of monuments are made upon application by the owner...
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Engineering Analysis with ANSYS Software Second Edition
PublicationThe best way to learn complex systems is by means of hands-on experience. With an innovative and clear tutorial based approach, this powerful book provides a comprehensive introduction to the fundamental areas of engineering analysis needed on research or commercial engineering projects. With its detailed step-by-step explanations and sample problems, this book will develop the reader's understanding of FEA and their ability to...
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Bloki Funkcjonalne Systemów Elektronicznych 22/23
e-Learning CoursesKurs zawiera materiały do wykładu (slajdy oraz materiały wideo) i laboratorium (instrukcje) z przedmiotu Bloki Funkcjonalne Systemów Elektronicznych.
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Bloki Funkcjonalne Systemów Elektronicznych 23/24
e-Learning CoursesKurs zawiera materiały do wykładu (slajdy) i laboratorium (instrukcje) z przedmiotu Bloki Funkcjonalne Systemów Elektronicznych.
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Residual MobileNets
PublicationAs modern convolutional neural networks become increasingly deeper, they also become slower and require high computational resources beyond the capabilities of many mobile and embedded platforms. To address this challenge, much of the recent research has focused on reducing the model size and computational complexity. In this paper, we propose a novel residual depth-separable convolution block, which is an improvement of the basic...
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Shadow Economy in Poland Recent Evidence Based on Survey Data
PublicationThe book provides an estimate of the size of the shadow economy in Poland. Using analogous data, it traces core determinants of the existence of the shadow economy in Poland. It compares results with neighbouring countries, and if possible, the remaining Central-Eastern economies. The book tells why the problem of the unreported economic activity matters; it presents the problem from different angles―economic, social and institutional....
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Praca projetkowa IV, P, Oce, lato 22/23 PG_00041790
e-Learning CoursesSpecjalność: Budowa Okrętów i Jachtów (WOiO), I stopnia - inżynierskie, stacjonarne, 2021/2022 - zimowy (obecnie sem. 5) Wykonanie modelu komputerowego 3D bloku statku z uwzględnieniem wybranych aspektów konstrukcyjno-technologicznych. Analiza transportu bloku. (Wykonanie projektu usztywnień transportowych, uchwytów transportowych, itp.). Wykonanie listy kompletacyjnej bloku statku.
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Praca projektowa III, P, sem.6, lato23/24, PG_00055303
e-Learning CoursesSpecjalność: Budowa Okrętów i Jachtów (WOiO), I stopnia - inżynierskie, stacjonarne, 2021/2022 - zimowy (obecnie sem. 5) Wykonanie modelu komputerowego 3D bloku statku z uwzględnieniem wybranych aspektów konstrukcyjno-technologicznych. Analiza transportu bloku. (Wykonanie projektu usztywnień transportowych, uchwytów transportowych, itp.). Wykonanie listy kompletacyjnej bloku statku.
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The influence of 4-substituted and unsubstituted derivatives of 1-nitroacridine on the cell cycle and induction of apoptosis in human cancer HT29 and HeLa S3.
PublicationZbadano wpływ pochodnych 1-nitroakrydyny C-1748 i C-857, w stężeniach biologicznie istotnych, na cykl życiowy oraz indukcję apoptozy komórek raka jelita grubego HT29 oraz raka szyjki macicy HeLa S3. Metodą cytometrii przepływowej wykazano, że 4-metylo-1-nitroakrydyna C-1748 powoduje akumulację komórek HT29 w fazie S i komórek HeLa S3 w fazie G2 cyklu komórkowego zaś związek C-857 indukuje akumulację komórek HT29 i HeLa S3 w fazie...
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plakat wystawy pt. "Zaspa Nova: osiedle i otoczenie | perspektywa 2030 | studium potencjału miejsca"
PublicationPlakat jest autorskim projektem plastycznym opartym o fotografię bloku mieszkalnego z Zaspy
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Andrzej Okuniewski dr inż.
PeopleEducation 2010-2014: Department of Inorganic Chemistry, Faculty of Chemistry, Gdańsk University of TechnologyPhD in chemical sciences (chemical sciences - chemistry, inorganic chemistry) 2009-2010: Faculty of Chemistry, Gdańsk University of TechnologyMaster of Chemistry (applied chemistry) 2005-2009: Faculty of Chemistry, Gdańsk University of Technologychemical engineer (applied chemistry) 2002-2005: II High School Władysław Pniewski...