Search results for: DRAD PROTEIN

• A surface-exposed DraD protein of uropathogenic Escherichia coli bearing Dr fimbriae may be expressed and secreted independently from DraC usher and DraE adhesin

  Publication

  • B. Zalewska-Piątek
  • R. Piątek
  • K. Bury
  • A. Samet
  • B. J. Nowicki
  • S. Nowicki
  • J. Kur

  - Year 2005

  Operon dra uropatogennych szczepów Escherichia coli Dr+ odpowiedzialny jest za proces bakteryjnej adhezji i inwazji. Operon dra kodujący fimbrie Dr zawiera sześć otwartych ramek odczytu - draA, draB, draC, draD, draP oraz draE. Fimbrie Dr zlokalizowane na powierzchni komórki bakteryjnej, zbudowane są z podjednostek białka DraE. Niewiele wiadomo na temat powierzchniowej ekspresji białka DraD oraz jego roli w procesie biogenezy fimbrii...

• PROTEIN EXPRESSION AND PURIFICATION

  Journals

  ISSN: 1046-5928 , eISSN: 1096-0279

• Molecular aspects of biogenesis of Escherichia coli Dr Fimbriae: characterization of DraB-DraE complexes

  Publication

  • R. Piątek
  • B. Zalewska-Piątek
  • O. Kolaj
  • M. Ferens
  • B. J. Nowicki
  • J. Kur

  - Year 2005

  Hemaglutynina Dr uropatogennych szczepów Escherichia coli jest fimbrialnym homopolimerem zbudowanym z podjednostek białkowych DraE kodowanych przez operon dra. Operon dra zawiera geny draB i draC, kodujące białka homologiczne do białek (białko opiekuńcze-białko kanałotwórcze) zaangażowanych w procesie biogenezy struktur polimerycznych eksprymowanych powierzchniowo. Białko DraB jest jednym z białek periplazmatycznych, należącym...

• Role of the disulfide bond in stabilizing and folding of the fimbrial protein DraE from uropathogenic Escherichia coli

  Publication

  • J. Pilipczuk
  • B. Zalewska-Piątek
  • P. Bruździak
  • J. Czub
  • M. Wieczór
  • M. Olszewski
  • M. Wanarska
  • B. Nowicki
  • D. Augustin-Nowacka
  • R. Piątek

  - JOURNAL OF BIOLOGICAL CHEMISTRY - Year 2017

  Dr fimbriae are homopolymeric adhesive organelles of uropathogenic Escherichia coli composed of DraE subunits, responsible for the attachment to host cells. These structures are characterized by enormously high stability resulting from the structural properties of an Ig-like fold of DraE. One feature of DraE and other fimbrial subunits that makes them peculiar among Ig-like domain-containing proteins is a conserved disulfide bond...

  Full text available to download

• Function and Frustration of Multi-Drug ABC Exporter Protein and Design of Model Proteins for Drug Delivery Using Protein Hydration Thermodynamics

  Publication

  • D. Urry
  • K. Urry
  • W. Szaflarski
  • M. Nowicki
  • M. Zabel

  - CURRENT PHARMACEUTICAL DESIGN - Year 2009

  Full text to download in external service

• Elastic-contractile model proteins: Physical chemistry, protein function and drug design and delivery

  Publication

  • D. Urry
  • K. Urry
  • W. Szaflarski
  • M. Nowicki

  - ADVANCED DRUG DELIVERY REVIEWS - Year 2010

  Full text to download in external service

• Protein & Cell

  Journals

  ISSN: 1674-800X , eISSN: 1674-8018

• PROTEIN JOURNAL

  Journals

  ISSN: 1572-3887 , eISSN: 1573-4943

• How proteins bind to DNA: target discrimination and dynamic sequence search by the telomeric protein TRF1

  Publication

  • M. Wieczór
  • J. Czub

  - NUCLEIC ACIDS RESEARCH - Year 2017

  Target search as performed by DNA-binding proteins is a complex process, in which multiple factors contribute to both thermodynamic discrimination of the target sequence from overwhelmingly abundant off-target sites and kinetic acceleration of dynamic sequence interrogation. TRF1, the protein that binds to telomeric tandem repeats, faces an intriguing variant of the search problem where target sites are clustered within short fragments...

  Full text available to download

• Biofilm formation as a virulence determinant of uropathogenic Escherichia coli Dr+ strains

  Publication

  • B. M. Zalewska-Piątek
  • S. I. Wilkanowicz
  • R. Piątek
  • J. Kur

  - Polish Journal of Microbiology - Year 2009

  Infekcje dróg moczowych stanowią największy problem zdrowotny dotykający miliony osób populacji ludzkiej każdego roku. Uropatogenne szczepy Escherichia coli są najczęstszym czynnikiem etiologicznym odpowiedzialnym za wywoływanie górnych i dolnych dróg moczowych. Powyższe szczepy bakteryjne produkują szereg czynników wirulentnych pośród, których wyróżnić można eksponowane powierzchniowo polimeryczne struktury adhezyjne (fimbrie/pile)...

  Full text available to download

• Extension of the Unres Package for Physics-Based Coarse-Grained Simulations of Proteins and Protein Complexes to Very Large Systems

  Publication

  • A. Sieradzan
  • C. Czaplewski
  • E. Lubecka
  • A. Lipska
  • A. Karczynska
  • A. Gieldon
  • R. Slusarz
  • M. Makowski
  • P. Krupa
  • M. Kogut... and 5 others

  - Biophysical Journal - Year 2021

  Full text to download in external service

• PROTEIN SCIENCE

  Journals

  ISSN: 0961-8368 , eISSN: 1469-896X

• ADVANCES IN PROTEIN CHEMISTRY

  Journals

  ISSN: 0065-3233

• JOURNAL OF PROTEIN CHEMISTRY

  Journals

  ISSN: 0277-8033

• PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

  Journals

  ISSN: 0887-3585 , eISSN: 1097-0134

• UNRES-Dock—protein–protein and peptide–protein docking by coarse-grained replica-exchange MD simulations

  Publication

  • P. Krupa
  • A. Karczyńska
  • M. Mozolewska
  • A. Liwo
  • C. Czaplewski

  - BIOINFORMATICS - Year 2021

  Full text to download in external service

• PROTEUS

  Journals

  ISSN: 0889-6348

• Probiotics and Antimicrobial Proteins

  Journals

  ISSN: 1867-1306 , eISSN: 1867-1314

• The Protein Folding Problem

  Publication

  • H. Scheraga
  • A. Liwo
  • S. Oldziej
  • C. Czaplewski
  • J. Pillardy
  • J. Lee
  • D. Ripoll
  • J. Vila
  • R. Kazmierkiewicz
  • J. Saunders... and 12 others

  - Year 2006

  Full text to download in external service

• Dead Sea Discoveries

  Journals

  ISSN: 0929-0761 , eISSN: 1568-5179

• PROTEIN AND PEPTIDE LETTERS

  Journals

  ISSN: 0929-8665 , eISSN: 1875-5305

• Influence of Osmolytes on Protein and Water Structure: A Step To Understanding the Mechanism of Protein Stabilization

  Publication

  • P. Bruździak
  • A. Panuszko
  • J. Stangret

  - JOURNAL OF PHYSICAL CHEMISTRY B - Year 2013

  Results concerning the thermostability of hen egg white lysozyme in aqueous solutions with stabilizing osmolytes, trimethylamine-N-oxide (TMAO), glycine (Gly), and its N-methyl derivatives, N-methylglycine (NMG), N,N-dimethylglycine (DMG), and N,N,N-trimethylglycine (betaine, TMG), have been presented. The combination of spectroscopic (IR) and calorimetric (DSC) data allowed us to establish a link between osmolytes’ influence on...

  Full text to download in external service

• CURRENT PROTEIN & PEPTIDE SCIENCE

  Journals

  ISSN: 1389-2037 , eISSN: 1875-5550

• Current Protocols in Protein Science

  Journals

  ISSN: 1934-3655

• Proteins

  Publication

  • Z. Sikorski

  - Year 2002

  Struktura białek wpływa na ich wartość odżywczą, właściwości funkcjonalne wżywności oraz reakcje w surowcach i produktach żywnościowych. Warunki prze-chowywania oraz obróbki w przemyśle i w czasie przygotowywania kulinarnegowywołują przemiany białek istotne dla jakości żywności. Przez celowe, enzy-matyczne i chemiczne modyfikowanie składu i struktury białek można wpływaćna ich właściwości funkcjonalne w żywności i wartość...

• The DraC usher in Dr fimbriae biogenesis of uropathogenic E. coli Dr+ strains

  Publication

  • B. Zalewska-Piątek
  • M. Kur
  • S. Wilkanowicz
  • R. Piątek
  • J. Kur

  - ARCHIVES OF MICROBIOLOGY - Year 2010

  Biogeneza fimbrii Dr kodowanych przez operon dra uropatogennych szczepów Escherichia coli (infekcje górnych dróg moczowych) odbywa się na bazie zakonserwowanego systemu sekrecji typu chaperone-usher. Funkcjonowanie powyższego systemu sekrecji opiera się na dwóch komponentach białkowych, periplazmatycznym chaperonie DraB i zewnątrzbłonowym kanale DraC. Białko DraB kontroluje proces składania podjednostek fimbrialnych DraE, natomiast...

  Full text to download in external service

• Biochemical characteristic of biofilm of uropathogenic Escherichia coli Dr+ strains.

  Publication

  • B. Zalewska-Piątek
  • S. Wilkanowicz
  • P. Bruździak
  • R. Piątek
  • J. Kur

  - MICROBIOLOGICAL RESEARCH - Year 2013

  Urinary tract infections caused by Escherichia coli are very common health problem in the developed countries. The virulence of the uropathogenic E. coli Dr+ IH11128 is determined by Dr fimbriae, which are homopolymeric structures composed of DraE subunits with the DraD protein capping the fiber. In this study, we have analyzed the structural and biochemical properties of biofilms developed by E. coli strains expressing Dr fimbriae...

  Full text available to download

• Alternative and New Protein Sources

  Publication

  • B. Sawicka
  • K. Umachandran
  • N. Nasir
  • D. Skiba

  - Year 2020

  Full text to download in external service

• On the Origin of Protein Superfamilies and Superfolds

  Publication

  • A. Magner
  • W. Szpankowski
  • D. Kihara

  - Scientific Reports - Year 2015

  Distributions of protein families and folds in genomes are highly skewed, having a small number of prevalent superfamiles/superfolds and a large number of families/folds of a small size. Why are the distributions of protein families and folds skewed? Why are there only a limited number of protein families? Here, we employ an information theoretic approach to investigate the protein sequence-structure relationship that leads to...

  Full text available to download

• Stabilizing agents and protein stability

  Publication

  • P. Bruździak
  • A. Panuszko
  • J. Stangret

  - Acta Biochimica Polonica - Year 2011

  Białka są kluczowymi elementami żywych organizmów, jak również efektywnymi katalizatorami w biotechnologii i medycynie. Szybki rozwój wielu gałęzi biotechnologii wiąże się z coraz większym zapotrzebowaniem na produkty białkowe charakteryzujące się wysoką stabilnością. Jednym ze sposobów osiągnięcia większej stabilności białek jest wykorzystanie małych związków organicznych, tzw. osmolitów. Do tej grupy związków należą aminokwasy,...

• Colloidal aspects of protein digestion

  Publication

  • A. Mackie
  • A. Macierzanka

  - CURRENT OPINION IN COLLOID & INTERFACE SCIENCE - Year 2010

  .

  Full text to download in external service

• Type II secretory pathway for surface secretion of DraD invasin from the uropathogenic Escherichia coli Dr+ strain

  Publication

  • B. Zalewska-Piątek
  • K. Bury
  • R. Piątek
  • P. Bruździak
  • J. Kur

  - JOURNAL OF BACTERIOLOGY - Year 2008

  Właściwości wirulentne uropatogennych szczepów Escherichia coli Dr+ IH11128 związane są z obecnością struktur fimbrialnych typu Dr i białka inwazyny DraD, które może na powierzchni komórki bakteryjnej pełnić rolę fimbrialnej podjednostki szczytowej. Ostatnie badania wykazały, że białko DraD jest eksponowane na powierzchni bakterii w dwóch formach: związanej ze strukturą fimbrialną i jako niezależna od fimbrii otoczka białkowa....

  Full text available to download

• Lessons learned during SRAD hybrid motor development

  Publication

  • M. Czapski
  • N. Szulc
  • J. Godlewska
  • W. Lachowski
  • N. Balogh
  • W. Deszczyński
  • K. Hucik
  • K. Zieliński
  • D. Kardaś
  • A. Rusin... and 2 others

  - Year 2022

  Student Researched and Developed (SRAD) hybrid rocket motor H-15 with total impulse of 15 $kNs$ was built. First version of the engine has average thrust of 3 $kN$, the second, improved one is prepared with an aim to have average thrust of 5 $kN$. Engine development was started from scratch and went through phases of: definition of design assumptions and constraints, numerical modelling to predict engine performance, CAD and CAM...

  Full text available to download

• Endocrine responses following exhaustive strength exercise with and without the use of protein and protein-carbohydrate supplements

  Publication

  • M. Wilk
  • M. Michalczyk
  • A. Gołaś
  • M. Krzysztofik
  • A. Maszczyk
  • A. Zając

  - Biology of Sport - Year 2018

  Full text to download in external service

• The importance of the shape of the protein-water interface of a kinesin motor domain for dynamics of the surface atoms of the protein

  Publication

  • A. Kuffel
  • J. Zielkiewicz

  - PHYSICAL CHEMISTRY CHEMICAL PHYSICS - Year 2012

  Single kinesin motor domain immersed in water has been investigated using molecular dynamics. It has been found that local properties of water in solvation shell change along with the nature of neighboring protein surface. However, a detailed analysis leads to the conclusion that the geometrical features of hydrogen bonds and overall structure of kinesin hydration water is not very different from bulk water. The local values of...

  Full text to download in external service

• The importance of the shape of the protein–water interface of a kinesin motor domain for dynamics of the surface atoms of the protein

  Publication

  • A. Kuffel
  • J. Zielkiewicz

  - PHYSICAL CHEMISTRY CHEMICAL PHYSICS - Year 2012

  A single kinesin motor domain immersed in water has been investigated using molecular dynamics. It has been found that local properties of water in the solvation shell change along with the nature of the neighboring protein surface. However, a detailed analysis leads to the conclusion that the geometrical features of hydrogen bonds and overall structure of kinesin hydration water are not very different from bulk water. The local...

  Full text to download in external service

• Occlusion phenomenon of redox probe by protein as a way of voltammetric detection of non-electroactive C-reactive protein

  Publication

  • A. Kowalczyk
  • J. Sęk
  • A. Kasprzak
  • M. Poplawska
  • I. Grudzinski
  • A. Nowicka

  - BIOSENSORS & BIOELECTRONICS - Year 2018

  Full text to download in external service

• Compensation of Dead Time Effects for Shunt Active Power Filters

  Publication

  • A. Cichowski
  • W. Śleszyński
  • J. Nieznański
  • P. Szczepankowski

  - Year 2015

  The paper presents a comprehensive approach to the compensation of the grid current distortion for shunt active power filter systems. Four different sources of current distortion are addressed: imperfect grid synchronization caused by the distortion in the grid voltages, time delays in the estimation of compensating currents and grid voltages, fluctuations of the dc bus voltage, and the distortion of inverter output voltages due...

  Full text to download in external service

• Minimum drag shape bodies moving in inviscid fluid - revisited

  Publication

  • K. Tesch
  • K. Kaczorowska-Ditrich

  - Transactions of the Institute of Fluid-Flow Machinery - Year 2017

  This paper presents the classic approach to minimum drag shape body problem, moving at hypersonic speeds, leading to famous power law shapes with value of the exponent of 3/4. Two- and three-dimensional cases are considered. Furthermore, an exact pseudo solution is given and its uselessness is discussed. Two new solutions are introduced, namely an approximate solution due to form of the functional and solution by means of optimisation...

  Full text to download in external service

• Control of voltage source inverter without dead-time effects.

  Publication

  • A. Lewicki
  • Z. Krzemiński

  - Year 2004

  W artykule zaproponowano metodę dokładnego generowania wektora napięcia o małej amplitudzie w falowniku napięcia. Zaprezentowano metodę modulacji szerokości impulsów, w której wyeliminowano koniecznosć wprowadzania czasów martwych oraz kompensacji ich wpływu na napięcie wyjsciowe przekształtnika

• Influence of windsurfing fin stiffness distribution on the lift-drag characteristics

  Publication

  • H. Pruszko
  • M. Reichel
  • T. Mikulski

  - Year 2023

  This article addresses the problem of determining the hydromechanical loads generated by flexible hydrofoils. The research was done on the example of the composite windsurfing fin for the RS:X monotype class. Despite the assumption of fins identity, everyday practice showed that variations of mechanical properties occur and strongly affect their performance. Therefore, we decided to study the differences between the windsurfing...

  Full text available to download

• PROTEIN ENGINEERING DESIGN & SELECTION

  Journals

  ISSN: 1741-0126 , eISSN: 1741-0134

• World Research Journal of Peptide and Protein

  Journals

  ISSN: 2278-4586

• Advances in Protein Chemistry and Structural Biology

  Journals

  ISSN: 1876-1623

• Current Topics in Peptide and Protein Research

  Journals

  ISSN: 0972-4524

• International Journal of Peptide and Protein Research

  Journals

  ISSN: 0367-8377

• AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

  Journals

  ISSN: 1350-6129 , eISSN: 1744-2818

• Iron–Sulfur Cluster Biogenesis Chaperones: Evidence for Emergence of Mutational Robustness of a Highly Specific Protein–Protein Interaction

  Publication

  • W. Delewski
  • B. Paterkiewicz
  • M. Manicki
  • B. Schilke
  • B. Tomiczek
  • S. Ciesielski
  • Ł. Nierzwicki
  • J. Czub
  • R. Dutkiewicz
  • E. Craig
  • J. Marszalek

  - MOLECULAR BIOLOGY AND EVOLUTION - Year 2016

  Biogenesis of iron–sulfur clusters (FeS) is a highly conserved process involving Hsp70 and J-protein chaperones. However, Hsp70 specialization differs among species. In most eukaryotes, including Schizosaccharomyces pombe, FeS biogenesis involves interaction between the J-protein Jac1 and the multifunctional Hsp70 Ssc1. But, in Saccharomyces cerevisiae and closely related species, Jac1 interacts with the specialized Hsp70 Ssq1,...

  Full text to download in external service

• The Role of Proteins in Food

  Publication

  • Z. Sikorski
  • I. Sinkiewicz

  - Year 2023

  This chapter describes the effect of proteins on the sensory attributes and the biological value and safety of foods. The role of proteins depends on their amino acid composition and structure, on changes due to storage and processing, as well as on interactions with other food components. The effect on the sensory quality of foods is brought about by hydrophobicity, solubility, water holding capacity, gelling, film formation,...

  Full text to download in external service

• U-Tube Method of Identification of Drag Parameters for High Permeability Materials

  Publication

  • M. Kaczmarek
  • R. Drelich
  • M. Pakuła

  - Year 2013

  Full text to download in external service