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Enzymatic activities behind degradation of glucosinolates
PublikacjaMyrosinase (thioglucosidase, EC 3.2.1.147) is the enzyme responsible for the hydrolysis of glucosinolates (GLs). In plant tissue, myrosinase and GLs are sequestered in separate cellular compartments. As a result of cell disruption, e.g., after pathogen attack or on chopping or grinding during food preparation, the myrosinase comes into contact with GLs and catalyzes the hydrolysis of thioglucosidic bond in GL structure. Consequently,...
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma-Recent Findings and Review
PublikacjaThe inflammatory process plays a significant role in the development of colon cancer (CRC). Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation but also impact carcinogenesis at all stages of the disease. Recent studies suggest that inflammation is of greater importance in the serrated pathway than in the adenoma-carcinoma pathway. Interleukins have gained the most attention due to their...
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Determination of isoprostanes in exhaled breath condensate samples by liquid chromatography coupled with tandem mass spectrometry
PublikacjaOxidative stress (OS) is a state of imbalance between continuously generating reactive oxygen species (ROS) during normal cell metabolism and mechanism of detoxifying oxygen radicals through a network of antioxidative enzymes. Isoprostanes are prostaglandin -like substances that are produced in vivo primarily by free radical-induced peroxidation of arachidonic acid. The measurement of isoprostanes in biological fluids and/or tissue...
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Rating mathematical models for first-pass of tracer in pCT lung studies
PublikacjaThis paper presents a comparison of model based on the Gauss function and the most commonly used Gamma-variate model in perfusion computed tomography (pCT) lung studies. It also verifies whether used model affects value of blood volume parameter. Three mean concentration-time curves were created from actual pCT measurements: arterial input function, blood vessels in lungs and lung parenchyma. On the basis of these mean curves we...
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Obtaining a Well-Trained Artificial Intelligence Algorithm from Cross-Validation in Endoscopy
PublikacjaThe article shortly discusses endoscopic video analysis problems and artificial intelligence algorithms supporting it. The most common method of efficiency testing of these algorithms is to perform intensive cross-validation. This allows for accurately evaluate their performance of generalization. One of the main problems of this procedure is that there is no simple and universal way of obtaining a specific instance of a well-trained...
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A PRELIMINARY STUDY ON THE OPTIMAL CHOICE OF AN IMPLANT AND ITS ORIENTATION IN VENTRAL HERNIA REPAIR
PublikacjaThis paper addresses the problem of ventral hernia repair. The main goals are to find an optimal surgical mesh for hernia repair and to define its optimal orientation in the abdominal wall to minimise the maximum force at the tissue-implant juncture. The optimal mesh is chosen from a set of orthotropic meshes with different stiffness ratios for typical hernia placement in the abdominal area. The implant is subjected to an anisotropic...
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Bioactive core material for porous load-bearing implants
PublikacjaSo far state of knowledge on biodegradable materials is reviewed. Among a variety of investigated materials, those composed of polymers and ceramics may be considered as only candidates for a core material in porous titanium alloy. The collagen and chitosan among natural polymers, polyhydroxy acids among synthetic polymers, and hydroxyapatite and tricalcium phosphate among ceramics are proposed for further research. Three essential...
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PERFORMANCE OF ENDOSCOPIC IMAGE ANALYSIS ALGORITHMS IN LARGE BOWEL VIDEOS PROCESSING
PublikacjaComputer-assisted endoscopy is a rapidly developing eld of study. Many image anal- ysis algorithms exist, achieving very high rates of eciency at processing single endoscopic images. However, most of them were never tested in processing real-life endoscopic videos. In the article such tests of 16 endoscopy image analysis algorithms are presented and dis- cussed. Tests were performed on two real-life endoscopic videos of a human...
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Chronic Rhinosinusitis—Microbiological Etiology, Potential Genetic Markers, and Diagnosis
PublikacjaChronic rhinosinusitis (CRS) is a significant public health problem. Bacterial colonization and impaired mucociliary clearance play a significant role in the inflammatory process. Several inflammatory pathways and host defense elements are altered in CRS, which may contribute to observed differences in the microbiome. To date, researching CRS has been difficult due to limited access to the studied tissue and a lack of available...
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The influence of the grid density of measurement points on damage detection in an isotropic plate by the use of elastic waves and laser scanning Doppler vibrometry
PublikacjaDamage detection in structural components, especially in mechanical engineering, is an 2 important element of engineering practice. There are many methods of damage detection, in which 3 changes in various parameters caused by the presence of damage are analysed. Recently, methods 4 based on the analysis of changes in dynamic parameters of structures, i.e. frequencies or mode shapes 5 of natural vibrations, as well as changes in...
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Synchro-photogrammetry in the measurement of objects in motion - the case study
PublikacjaSynchronous photographs and digital photogrammetry methods in a measurement of objects in motion - the experiment. In the following paper, a case study example of a photogrammetric method based on synchronous digital photographs has been presented. This measurement method is an effective solution for tracking of moving objects, dynamic studies and dimensioning of geometry movements. Nowadays, the use of synchronous photography...
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Technical Engine for Democratization of Modeling, Simulations, and Predictions
PublikacjaComputational science and engineering play a critical role in advancing both research and daily-life challenges across almost every discipline. As a society, we apply search engines, social media, and se- lected aspects of engineering to improve personal and professional growth. Recently, leveraging such aspects as behavioral model analysis, simulation, big data extraction, and human computation is gain- ing momentum. The nexus...
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Physics augmented classification of fNIRS signals
PublikacjaBackground. Predictive classification favours performance over semantics. In traditional predictive classification pipelines, feature engineering is often oblivious to the underlying phenomena. Hypothesis. In applied domains such as functional Near Infrared Spectroscopy (fNIRS), the exploitation of physical knowledge may improve the discriminative quality of our observation set. Aims. Give exemplary evidence that intervening the...
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Poprawa jakości klasyfikacji głębokich sieci neuronowych poprzez optymalizację ich struktury i dwuetapowy proces uczenia
PublikacjaW pracy doktorskiej podjęto problem realizacji algorytmów głębokiego uczenia w warunkach deficytu danych uczących. Głównym celem było opracowanie podejścia optymalizującego strukturę sieci neuronowej oraz zastosowanie uczeniu dwuetapowym, w celu uzyskania mniejszych struktur, zachowując przy tym dokładności. Proponowane rozwiązania poddano testom na zadaniu klasyfikacji znamion skórnych na znamiona złośliwe i łagodne. W pierwszym...
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PCR test for Microsporum canis identification
PublikacjaMicrosporum canis, for which the natural hosts are cats and dogs, is the most prevalent zoophilic agent causing tinea capitis and tinea corporis in humans. We present here a diagnostic PCR test for M. canis, since its detection and species identification is relevant to the choice of treatment and to the understanding of a probable source of infection. An M. canis-specific PCR was evaluated using 130 clinical isolates of dermatophytes...
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Molecular targets for antifungals in amino acid and protein biosynthetic pathways
PublikacjaFungi cause death of over 1.5 million people every year, while cutaneous mycoses are among the most common infections in the world. Mycoses vary greatly in severity, there are long-term skin (ringworm), nail or hair infections (tinea capitis), recurrent like vaginal candidiasis or severe, life-threatening systemic, multiorgan infections. In the last few years, increasing importance is attached to the health and economic problems...
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Emulsifying blends based on natural fats for eco-design of O/W emulsions
PublikacjaEmulsifier blends are most often used to stabilize and modulate the properties of cosmetic and pharmaceutical emulsions, such as skin care or application-related consistency. However, the rational design of such emulsifier blends is often not well understood, especially when their ingredients are natural raw materials. This study aimed to analyze the influence of natural fatty ingredients selected as emulsifiers on the emulsion...
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Current risk analysis and management issues in technical systems.
PublikacjaDealing with the reliability and safety of industrial hazardous plants requires taking into account relevant interdisciplinary scientific knowledge and some existing approaches based on so-called good engineering practice, also those included in the international standards and guidelines. In this article an approach is proposed how to integrate the functional safety concept with information security aspects in the design and management...
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O modelowaniu numerycznym dźwigarów zespolonych
PublikacjaThe paper is a general review of theoretical problems and corresponding numerical procedures actually available in commercial engineering software. Several possibilities of numerical simulation for composite girders are presented. Effectivity of meshing is showed on the simple example. Finally several examples of structural numeric models for real bridges are included. In the author's opinion, presented available procedures for...
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Hybrid approach to ontology specification and development
PublikacjaIn this chapter a first draft of a hybrid ontology development approach is presented. The context of this method encompasses the multi-agent system equipped with knowledge bases and inferring engine. The process of ontology engineering appears as a complex issue, as it addresses different point-views of both, a client and a modeler with a requirements/system analyst. Regarding this, an approach based on the knowledge preprocessing...
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Strain gauges monitoring of arch bridge over the Vistula river in Toruń during construction
PublikacjaIn 2013 one of the biggest Polish road bridges over the Vistula was built in Torun. Considering the use of original engineering solutions and innovative assembly it was decided on monitoring of strain gauges and assessment of building’s behaviour during its construction. The research was aimed at determining the degree of strain and the assessment of proper work of main arch girders during assembly phases. This work presents the...
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On Von Karman Equations and the Buckling of a Thin Circular Elastic Plate
PublikacjaWe shall be concerned with the buckling of a thin circular elastic plate simply supported along a boundary, subjected to a radial compressive load uniformly distributed along its boundary. One of the main engineering concerns is to reduce deformations of plate structures. It is well known that von Karman equations provide an established model that describes nonlinear deformations of elastic plates. Our approach to study plate deformations...
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Błędy dotyczące kotwienia w budownictwie
PublikacjaW artykule zwrócono uwagę na typowe błędy w projektowaniu oraz wykonawstwie systemów kotwienia w budownictwie. Omówiono normowe zalecenia dotyczące obliczeń nietypowych elementów. Przedstawiono kilka przykładów błędnego wykonania kotwienia z rzeczywistej realizacji. Skomentowano rodzaj błędów i ich przyczynę.
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DiSTFAG method robust to gross errors in monitoring displacements and strains in unstable reference systems
PublikacjaThe DiSTFA method (Displacements and Strains using Transformation and Free Adjustment) was presented in Kamiński (2009). The method has been developed for the determination of displacements and strains of engineering objects in unstable reference systems, as well as for examining the stability of reference points. The DiSTFAG (Gross errors) method presented in the paper is the extension of the DiSTFA method making it robust to...
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Review of historical buildings' foundations
PublikacjaThe paper presents in brief the history of foundation engineering with a particular regard to its development, applied techniques and materials. Different types of old foundations in relation to various soil conditions are considered. Basic methods of preservation of old foundations, with special emphasis given to their faults and advantages are discussed. Finally, some problems of the reuse of pre-existing foundations are raised....
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Emotion Recognition and Its Applications
PublikacjaThe paper proposes a set of research scenarios to be applied in four domains: software engineering, website customization, education and gaming. The goal of applying the scenarios is to assess the possibility of using emotion recognition methods in these areas. It also points out the problems of defining sets of emotions to be recognized in different applications, representing the defined emotional states, gathering the data and...
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Pierwszy w Polsce Międzynarodowy Zabytek Inżynierii Budowlanej - most lisewski przez Wisłę w Tczewie
PublikacjaW artykule przedstawiono rys historyczny powstania pierwszego stałego mostu drogowo-kolejowego przez Wisłę w Tczewie (1857) oraz jego kolejnych przebudów (1911, 1939, 1945-1972, 2002). Na podstawie przeprowadzonej zabytkoznawczej analizy wartościującej to dzieło pruskiej inżynierii uzasadniono fakt nadania mu w 2004 r. statusu ''International historic civil engineering landmark'' przez American Society of Civil Engineers.
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Exergy analysis of the Szewalski cycle with a waste heat recovery system
PublikacjaThe conversion of a waste heat energy to electricity is now becoming one of the key points to improve the energy efficiency in a process engineering. However, large losses of a low-temperature thermal energy are also present in power engineering. One of such sources of waste heat in power plants are exhaust gases at the outlet of boilers. Through usage of a waste heat regeneration system it is possible to attain a heat rate of approximately...
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Expedited Simulation-Driven Multi-Objective Design Optimization of Quasi-Isotropic Dielectric Resonator Antenna
PublikacjaMajority of practical engineering design problems require simultaneous handling of several criteria. Although many of design tasks can be turned into single-objective problems using sufficient formulations, in some situations, acquiring comprehensive knowledge about possible trade-offs between conflicting objectives may be necessary. This calls for multi-objective optimization that aims at identifying a set of alternative, Pareto-optimal...
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Manufacturing Data Analysis in Internet of Things/Internet of Data (IoT/IoD) Scenario
PublikacjaComputer integrated manufacturing (CIM) has enormous benefits as it increases the rate of production, reduces errors and production waste, and streamlines manufacturing sub-systems. However, there are some new challenges related to CIM operating in the Internet of Things/Internet of Data (IoT/IoD) scenarios associated with Industry 4.0 and cyber-physical systems. The main challenge is to deal with the massive volume of data flowing...
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Power electronic systems as a crucial part of Smart Grid infrastructure - a survey
PublikacjaThis article gives a tutorial overview of the most important issues related to the use of power electronic systems in power engineering, with respect to the urgent need for modernization of existing grids in the direction of intelligent networks. The main problems and conditions bound up with the construction of Smart Grids and the location, as well as functioning in them of the most important power electronic systems are presented...
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Matrix Strengthening the Identification of Observations with Split Functional Models in the Squared Msplit(q) Estimation Process
PublikacjaThis article addresses the issue of raising the level of identification of observations with either single or more split functional models in the squared Msplit(q) estimation process. The theoretical part of the study presents the theoretical grounds for the classical method for estimating parameters in a split functional model and proposes a modification of the computational algorithm to increase the quality of the determinations...
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Various cases of preservation and adaptive reuse Heritage Buildings in the Port of Gdynia
PublikacjaThe port of Gdynia contains a diverse range of heritage assets, starting with its spatial layout which is an urban concept designed in the first half of the 1920s. It is important to point out, this historically-shaped harbor space is preserved in its general idea and still functioning in port activities. Another significant element is the structural, technological solution which was the basis for constructing the entire port area...
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Antioxidant Interactions between Major Phenolic Compounds Found in 'Ataulfo' Mango Pulp: Chlorogenic, Gallic, Protocatechuic and Vanillic Acids
PublikacjaPhenolic compounds are known to have antioxidant capacity; however, there is little information about molecular interactions between particular phenolics found in fruits at different developmental stages. Therefore, the total antioxidant capacity of the phenolic compounds of a fruit may not correspond to the sum of individual antioxidant capacity given by antioxidants from that tissue. In this study, individual antioxidant capacity...
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Nanotubular oxide layers and hydroxyapatite coatings on porous titanium alloy Ti13Nb13Zr
PublikacjaThe surface condition of an implant has a significant impact on response occurring at the implant-biosystem border. The knowledge of physical-chemical and biological processes allows for targeted modification of biomaterials to induce a specified response of a tissue. The present research was aimed at development of technology composing of obtaining the nanotube oxide layers on a porous titanium alloy Ti13Nb13Zr, followed by the...
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Tools for Automatic Wound Healing Evaluation
PublikacjaFinal results of the research project devoted to development of a new objective and quantitative method of post cardiosurgery wound healing diagnostics, already preliminary discussed at the QIRT 2014 Conference, is presented. We assumed that thermal processes should be effective in subtle description of temporal changes of tissue thermal properties after surgical interventions. To prove this assumption more than 400 patients after...
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Recent advances in electrochemically surface treated titanium and its alloys for biomedical applications: A review of anodic and plasma electrolytic oxidation methods
PublikacjaNowadays, titanium and its alloys are widely used materials in implantology. Nevertheless, the greatest challenge is still its appropriate surface treatment in order to induce optimal properties, which facilitates formation of a permanent bond between the implant and human tissue. The use of electrochemical treatment such as anodic oxidation or plasma electrolytic oxidation allows for the production of porous coating that mimics...
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Large hydrodynamic thrust bearing: Comparison of the calculations and measurements
PublikacjaHydrodynamic thrust bearings, used to carry axial loads in heavily loaded shafts of water power plants hydro turbines, can reach outer diameters even exceeding 5 m. In such large objects scale effect could be observed. According to this, allowable bearing specific load assuring safe operation of the bearings has to be decreased, which increases thrust bearing dimensions. This effect is caused by excessive thermal deflections of...
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Wirówka geotechniczna - historia, modelowanie i współczynniki skali
PublikacjaRozwój modelowania zjawisk geotechnicznych w wirówce. Historia rozwoju urządzenia. Przyczyny wykorzystania wirówki geotechnicznej przez ośrodki naukowe i biura inżynieryjne. Obecny status urządzenia w edukacji i przemyśle. Podstawy teoretyczne badań modelowych w wirówce geotechnicznej. Lista wybranych zależności korelacyjnych. Przegląd i dyskusja wybranych współczynników skali.
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Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis
PublikacjaPsoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors regulating gene expression play a key role. In the “genomic era”, genome-wide association studies together with target genotyping platforms performed in different ethnic populations have found more than 50 genetic susceptible markers associated with the risk of psoriasis which have been identified so far. Up till now, the strongest association...
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Technology of an adhesive silicone film as drug carrier in transdermal therapy I. Analytical methods used for characterization and design of the universal elastomer layers
PublikacjaSilicone polymers possess unique properties, which make them suitable for many different applications, for example in the pharmaceutical and medical industry. To create an adhesive silicone film, the appropriate silicone components have to be chosen first. From these components two layers were made: an adhesive elastomer applied on the skin, and a non-adhesive elastomer on the other side of the film. The aim of this study was...
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The Use of Liquid Crystal Thermography in Selected Technical and Medical Applications—Recent Development
PublikacjaThermochromic liquid crystals (TLC) and true-colour digital image processing have been successfully used in non-intrusive technical, industrial and biomedical studies and applications. Thin coatings of TLC at surfaces are utilized to obtain detailed temperature distributions and heat transfer rates for steady or transient processes. Liquid crystals also can be used to make the temperature and velocity fields in liquids visible...
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Synergistic Effects of Propolis Combined with 2-Phenoxyethanol and Antipyretics on the Growth of Staphylococcus aureus
PublikacjaThe present investigation aimed to assess the combinational effect of commonly usedantipyretics and antiseptics with ethanolic extracts of propolis (EEPs) on the growth inhibition ofStaphylococcus aureus. The broth microdilution checkerboard assay revealed synergistic interactionsbetween all investigated antipyretics, namely acetylsalicylic acid, ibuprofen, and acetaminophen,with EEPs samples. The values of the fractional inhibitory...
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Specific detection of Alternaria alternata by PCR and real-time PCR
PublikacjaFungi of Alternaria genus are cosmopolitan organisms, which spores can be found in the air, soil, water, clothing and food. They commonly occur as saprotrophs on the plant remains, contributing to the decomposition of organic matter. Additionally, they are components of the normal human and animal skin flora. Alternaria spp. are also known human allergens, causing hay fever and allergic reactions that can lead to the development...
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Towards large-scale application of nanoporous materials in membranes for separation of energy-relevant gas mixtures
PublikacjaMembranes containing nanoporous materials (such as zeolites, metal–organic materials and 2D materials such as graphene derivatives) may allow more efficient separation of gas mixtures relevant to emerging energy technologies. For example, such membranes could be applied in the separation of gases containing mixtures of carbon dioxide (CO2) and hydrogen (H2). However, these membranes are currently at a relatively low technology...
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Exposure scenario and risk assessment of infants and newborns to bisphenols and their derivatives from diapers
PublikacjaNewborns and infants are more sensitive to harmful compounds such as bisphenols and their derivatives because of their not fully developed detoxification mechanism. Exposure to these substances can lead to developmental problems and health consequences in adulthood. Since disposable baby diapers are used from the first days of life and remain in contact with the baby skin, it seems important to monitor the levels of endocrine disrupting chemicals...
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Parametric method applicable in calculating breakout force and time for lifting axisymmetric objects from seabed.
PublikacjaThe issue of calculating parameters for lifting objects of axisymmetric shapes from the seabed is studied. The article presents the results of numerical simulation examination of the equation formulated by Foda for the force needed to extricate the object from the seabed depending on soil and water parameters, extrication speed, and object diameter. The simulations were performed within the range of parameters characteristic for...
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Comparison of centralized and decentralized preemption in MPLS networks
PublikacjaPreemption is one of the crucial parts of the traffic engineering in MPLS networks. It enables allocation of high-priority paths even if the bandwidth on the preferred route is exhausted. This is achieved by removing previously allocated low-priority traffic, so as enough free bandwidth becomes available. The preemption can be performed either as a centralized or a decentralized process. In this article we discuss the differences...
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Multimedia in teaching economics and management in higher education.
PublikacjaNowadays, the use of multimedia teaching materials at universities makes a standard practice. However their saturation is still quite low comparing to the expectations of students - the main consumers of the information contained therein. This article will present the results of research conducted among students of Management and Engineering Management carried at the Technical University of Gdańsk. Some students of Computer Science...
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Establishing Relationships between Parameters of the controlled Compaction Soil by Using Various In-Situ Tests
PublikacjaThe aim of research was evaluating reliable correlations between chosen soil parameters describing state of surface layers of soil. The paper presents site comparative tests based on the light falling weight deflectometer (LFWD), the static plate load tester (VSS), the dynamic probing light tester (DPL) and the bearing ratio tester (CBR in-situ) with relationships between soil state parameters. All featured in-situ...