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wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: ANTITUMOR DRUG RESISTANCE
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Wood Moisture-Content Measurement Accuracy of Impregnated and Nonimpregnated Wood
PublikacjaThe influence of the impregnation process of pine wood (Pinus sylvestris L.) samples on the electrical resistance changes and the moisture-content measurement accuracy is presented in this paper. In this study, the resistances of impregnated and nonimpregnated green pine timber harvested from northern Poland were compared. An impregnation method based on a vacuum-pressure chamber was used. Copper salts were applied as the impregnated...
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Synthesis of disubstituted 1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acids derivatives
Publikacja1,3,4,9-tetrahydropyrano[3,4-b ]indole-1-acetic acid derivatives are of interest for pharmaceutical research as a core structure for synthesis of biological active substance - Etodolac (selective Cyclooxygenase-2 inhibitor, which belongs to the Non-steroidal Anti-inflammatory Drug, NSAID, that shows a clin-ically effective analgesic and anti-inflammatory activity). Here the way of synthesis of two 1,3,4,9-tetrahydropyrano[3,4-b...
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Comparative molecular modelling of biologically active sterols
PublikacjaMembrane sterols are targets for a clinically important antifungal agent – amphotericin B. The relatively specific antifungal action of the drug is based on a stronger interaction of amphotericin B with fungal ergosterol than with mammalian cholesterol. Conformational space occupied by six sterols has been defined using the molecular dynamics method to establish if the conformational features correspond to the preferential interaction...
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Graphene Production and Biomedical Applications: A Review
PublikacjaGraphene is a two-dimensional nanomaterial composed of carbon atoms with sp2 hybrid orbitals. Both graphene and graphene-based composite have gained broad interest among researchers because of their outstanding physiochemical, mechanical, and biological properties. Graphene production techniques are divided into top-down and bottom-up synthesis methods, of which chemical vapor deposition (CVD) is the most popular. The biomedical...
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Results of modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models using Aliivibrio fischeri bacterium as model organism
Dane BadawczeThe research was concerned with verifying the impact of mixtures of nine pharmaceuticals against a selected organism, i.e., the bacterium Aliivibrio fischeri. A. fisheri is used as a model organism in the monitoring of acute toxicity in environmental and reference samples in Microtox® systems. Tested pharmaceuticals, namely: diclofenac (sodium salt),...
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Thermodynamics aspects of interactions between acridine derivatives and DNA
PublikacjaDNA is a molecular target for many anticancer and antiviral drugs. Therefore, a clear understanding of the interaction of small molecules with DNA is important in the rational design of ligands that can bind to DNA with high affinity and selectivity. There are several methods to investigate interactions between drug and DNA. Some of them measure changing into DNA structures, such as lengthening and untwisting of helix of DNA. Other...
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A rapid and sensitive method for the quantitative analysis of ibuprofen and its metabolites in equine urine samples by gas chromatography-tandem mass spectrometry
PublikacjaIbuprofen is widely used in human and veterinary medicine for the treatment of chronic pain as well as rheumatic and musculoskeletal disorders. However, t he anal- gesic and anti-inflammatory properties of Ibuprofen have contributed to frequent drug abuse in equestr ian s ports. A sensitive and rapid gas chromatography with tandem mass spectrometry based method with a simple liquid-liquid extraction and deriva- tization requiring...
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Occurrence of antimicrobial resistant bacteria in environment and the statistical analysis of this phenomenon
PublikacjaIntroduction: In this study the occurrence of antimicrobial resistance patterns among fecal indicators (Escherichia coli and Enterococcus spp.) was analyzed in water and wastewater samples. The trends in antimicrobial resistance were analyzed using basic statistical methods. Methods: Samples were obtained from two local watercourses (Oliwski Stream and Reda River) as well as from the wastewater treatment plant (WWTP) Gdansk - Wschod....
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An investigation of microstructural basis for corrosion behavior of Al-CNT composites fabricated by SPS
PublikacjaIn this research effect of the addition of multi-wall carbon nanotubes (MWCNTs) as additive powder on microstructure and corrosion behavior of fabricated Al-CNT composites was studied. The aluminum powder and CNTs were mixed with high energy planetary ball-mill. It is observed that by increasing milling time, the uniformity of CNTs on aluminum matrix and consequently corrosion resistance of Al-CNT composite is increased. On the...
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Computational complexity and length of recorded data for fluctuation enhanced sensing method in resistive gas sensors
PublikacjaThis paper considers complexity and accuracy of data processing for gas detection using resistance fluctuation data observed in resistance gas sensors. A few selected methods were considered (Principal Component Analysis – PCA, Support Vector Machine – SVM). Functions like power spectral density or histogram were used to create input data vector for these algorithms from the observed resistance fluctuations. The presented considerations...
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Short-term measurement of physiological parameters - child (2)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Short-term (5 minutes) measurements of physiological parameters were performed on the healthy...
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Recent breakthroughs in the stability testing of pharmaceutical compounds
PublikacjaPharmaceutical development is mostly focused on the research leading to approval of a new and viable active substance. However, there is a number of old generation compounds that are still being used in contemporary medicinal practice. So that new analytical developments should cover not only the safety of newly developed drug substances, which is obvious, but should also be directed into the search of individual stability issues...
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Polysaccharide-based electroconductive hydrogels: Structure, properties and biomedical applications
PublikacjaArchitecting an appropriate platform for biomedical applications requires setting a balance between simplicity and complexity. Polysaccharides (PSAs) play essential roles in our life in food resources, structural materials, and energy storage capacitors. Moreover, the diversity and abundance of PSAs have made them an indispensable part of food ingredients and cosmetics. PSA-based hydrogels have been extensively reviewed in biomedical...
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Wpływ kierowcy na opór toczenia samochodu
PublikacjaW pracy omówiono wpływ zachowań kierowcy na opory toczenia pojazdu w ruchu drogowym. Można tu wyróżnić styl jazdy kierowcy oraz jego dbałość o pojazd. Przedstawiono wzrost oporu toczenia w aspekcie dynamicznego przyspieszania oraz szybkiej jazdy na zakręcie. Przeanalizowano także wpływ na opór toczenia takich czynników jak: ciśnienie w ogumieniu obciążenie promieniowe, zbieżność kół jezdnych samochodu oraz zużycie ogumienia.
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Human-associated bacteria and their mobile genetic elements - important minority in wastewater and wastewater impacted ecosystems
PublikacjaSince human-associated bacteria have been recognized as vectors in two - way gene transmission between the pathogenic and environmental populations, health hazard connected with wastewater discharge requires reevaluation. In this paper the particular attention was given to antimicrobial-resistance of Escherichia coli and enterococci isolated from wastewater and wastewater impacted environments. The obtained results showed that...
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Long-term measurement of physiological parameters - a teenager (60 minutes) - the 2nd serie
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (105 minutes)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (105 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (100 minutes)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (100 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - an adult (100 minutes)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (100 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - an adult (70 minutes)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (70 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - a teenager (60 min)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - an adult (60 minutes)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (60 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - child (120 min)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.Long-term (120 minutes) measurement of physiological parameters was performed on the healthy...
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Long-term measurement of physiological parameters - patient 1 (serie 5)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 3 (serie 11)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 2 (serie 20)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 11)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 3 (serie 22)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 4 (serie 17)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 4 (serie 3)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (4 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 15)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 2 (serie 11)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (6 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 22)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (4 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 10)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 4 (serie 12)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 14)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 3 (serie 15)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 3 (serie 17)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 4 (serie 23)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 23)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 4 (serie 8)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 2 (serie 8)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 2 (serie 4)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 16)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 3 (serie 20)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 4 (serie 1)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (3 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 2 (serie 10)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 3 (serie 14)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 1 (serie 6)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (4 hours) measurement of physiological parameters was performed on the healthy volunteers...
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Long-term measurement of physiological parameters - patient 2 (serie 6)
Dane BadawczeThe data set was obtained during the project focus on the determination of changes in physiological parameters due to a stressful situation.The measurements were conducted with the system which consists e.g. sensors of temperature, skin resistance, and pulse.A long-term (5 hours) measurement of physiological parameters was performed on the healthy volunteers...