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Wyniki wyszukiwania dla: HUMAN TUMOR XENOGRAFTS
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HUMAN MOLECULAR GENETICS
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Nature Human Behaviour
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Determination of Heavy Metals Concentration in Water and Soil at Various Locations in Lahore and their Harmful Impacts on Human and Plants life
PublikacjaHeavy metals poisoning of soil and water has resulted from industrial expansion in Lahore, Pakistan, creating a significant environmental hazard. As a result, monitoring the contamination of soil and water around industrial sites is critical. The fact that higher concentrations of heavy metals have a negative influence on both plants and human life and this cannot be ignored. Higher heavy metal concentrations have a direct impact...
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Reply to Comment on ‘Nanodiamond incorporated human liver mimicking phantoms: prospective calibration medium of magnetic resonance imaging’
PublikacjaDependence of the spin–lattice (T1) relaxation times on the nanodiamond concentration in human liver phantoms is discussed. Factors affecting stability and and reproducibility of these phantoms are presented. The need for comparative measurements on multiple MRI scanners for better understanding of potential variations in the obtained imaging data is emphasised.
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CNN Architectures for Human Pose Estimation from a Very Low Resolution Depth Image
PublikacjaThe paper is dedicated to proposing and evaluating a number of convolutional neural network architectures for calculating a multiple regression on 3D coordinates of human body joints tracked in a single low resolution depth image. The main challenge was to obtain a high precision in case of a noisy and coarse scan of the body, as observed by a depth sensor from a large distance. The regression network was expected to reason about...
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The effect of UV-C irradiation on lipids and selected biologically active compounds in human milk
PublikacjaThe effect of UV-C irradiation of human milk on lipid oxidation, content of antioxidants (vitamin C and catalase, CAT) and bactericidal compounds (lysozyme), as well as the total antioxidant capacity (TAC), of the breast milk was investigated. In parallel, the extent of inactivation of some bacteria was also determined. UV-C at doses from 85 to 740 J L−1 caused total inactivation of Escherichia coli and Staphylococcus aureus, but...
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The dispersive micro-solid phase extraction method for MS-based lipidomics of human breast milk*
PublikacjaA simple and rapid microextraction method ensuring high lipidome coverage was developed for liquid chromatography mass spectrometry (LC-MS)-based lipidomics of human breast milk. The dispersive microsolid phase extraction (D-µ-SPE) technique, coupled with the design of experiment (DoE) method, enabled the study of the influence of several conditions (desorption solvent, stationary phase ratio, and sorption and desorption time)...
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Alphitobius diaperinus larvae (lesser mealworm) as human food – An approval of the European Commission – A critical review
PublikacjaDue to the increasing threat of climate change and the need for sustainable food sources, human consumption of edible insects or entomophagy has gained considerable attention globally. The larvae of Alphitobius diaperinus Panzer (Coleoptera: Tenebrionidae), also known as the lesser mealworm, have been identified as a promising candidate for mass-rearing as a food source based the on evaluation on several aspects such as the production...
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Network oscillations modulate interictal epileptiform spike rate during human memory
PublikacjaEleven patients being evaluated with intracranial electroencephalography for medically resistant temporal lobe epilepsy participated in a visual recognition memory task. Interictal epileptiform spikes were manually marked and their rate of occurrence compared between baseline and three 2 s periods spanning a 6 s viewing period. During successful, but not unsuccessful, encoding of the images there was a significant reduction in...
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Numerical model of human head phantom to ensure dosimetry of dose components for boron neutron capture therapy
PublikacjaExtremely important aspects of the boron neutron capture therapy are, first of all, administering to the patient a boron compound that selectively reaches the neoplastic cells, and in the second step, the verification of the irradiation process. This paper focuses on the latter aspect, which is the detailed dosimetry of the processes occurring after the reaction of thermal neutrons with the boron-10 isotope. The results of computer...
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Determination of trace levels of eleven bisphenol A analogues in human blood serum by high performance liquid chromatography–tandem mass spectrometry
PublikacjaChemicals showing structural or functional similarity to bisphenol A (BPA), commonly called BPA analogues, have recently drawn scientific attention due to their common industrial and commercial application as a substitute for BPA. In the European Union, the use of BPA has been severely restricted by law due to its endocrine disrupting properties. Unfortunately, it seems that all BPA analogues show comparable biological activity,...
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A miniaturized solid-contact potentiometric multisensor platform for determination of ionic profiles in human saliva
PublikacjaThis paper describes a miniaturized multisensor platform (MP-ISES) consisting of electrodes: a reference one (RE) and ion-selective electrodes (ISEs) for monitoring Na+, K+, Ca2+, Mg2+, Cl−, and SCN− ions and pH in human saliva. Gold electrode surface was modified by deposition of two layers: electrosynthesized PEDOT:PSS forming an intermediate layer, and ion-selective membrane. The developed ISEs were characterized by a wide linear...
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Development of chromatographic and mass spectrometry conditions for untargeted lipidomic analysis of human breast milk
PublikacjaHuman breast milk (HBM) is a complex biofluid containing components which are essential for the proper growth of the newborn (for example nutrients such as carbohydrates, proteins, lipids) and also bioactive substances. According to the literature, most of studies involving HBM nutrients investigations focused essentially on the determination of proteins. The molecular composition of lipids in HBM is not well known as the protein...
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Expression of epithelial to mesenchymal transition-related markers in lymph node metastases as a surrogate for primary tumor metastatic potential in breast cancer
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Do not die, become senescent: a new type of cellular resistance induced by topoisomerase II inhibitors in tumor cells with functional p53
PublikacjaJednym z efektów wywoływanych przez związki przeciwnowotworowe w komórkach nowotworowych jest trwałe zahamowanie wzrostu, związane z pojawieniem się markerów procesu starzenia komórkowego. Proponuje się, że może to być nowy sposób na zahamowanie postępu choroby nowotworowej. W naszych badaniach wykazujemy, że zahamowanie wzrostu indukowane przez związki z grupy inhibitorów topoizomerazy II w komórkach raka płuc A549 jest związane...
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Determination of oxygen saturation and photosensitizer accumulation in the tumor with the help of LEDand laser diode-based irradiation sources and fiber-optics probes
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Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients
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Tensile modulus of human orbital wall bones cut in sagittal and coronal planes
PublikacjaIn the current research, 68 specimens of orbital superior and/or medial walls taken from 33 human cadavers (12 females, 21 males) were subjected to uniaxial tension untill fracture. The samples were cut in the coronal (38 specimens) and sagittal (30 specimens) planes of the orbital wall. Apparent density (ρapp), tensile Young’s modulus (E-modulus) and ultimate tensile strength (UTS) were identified. Innovative test protocols were...
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α-Pinene, 3-carene and d-limonene in indoor air of Polish apartments: The impact on air quality and human exposure
PublikacjaMonoterpenes are among most ubiquitous volatile organic compounds (VOCs) to be detected in indoor air. Since the quality of indoor air is considered important for inhabitants' well-being, the present study aimed at investigating impact of human activity on levels of selected monoterpenes applying passive sampling technique followed by thermal desorption and gas chromatography coupled mass spectrometry. One of the objectives of...
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Drill holes decrease cancellous bone strength: A comparative study of 33 paired osteoporotic human and 9 paired artificial bone samples
PublikacjaThis study was designed to compare compressive strength of cancellous bone retrieved from the femoral head in a specimen with and without guide wire hole, with comparison to synthetic bone samples. Femoral heads retrieved from 33 patients who sustained femoral neck fractures and underwent hip arthroplasty were cut into cuboids leaving two matching samples from the same femoral head. Similar samples were prepared from synthetic femurs....
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Tensile and flexural moduli for human orbital wall bones – comparative study
PublikacjaThe main aims of the current research were: (1) to analyze in detail the tensile modulus and ultimate tensile strength (UTS) of orbital wall bones separately for the left and right orbit of the same cadaver and (2) to compare the obtained results with a flexural modulus of the left and right orbit reported earlier by A. C. van Leeuwen et al. [14]. A set of 54 specimens of orbital superior and/or medial walls harvested from 16 human...
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Classifying the transformation products (TPs) of emerging contaminants (ECs) for prioritizing research into their impact on the environment and human health
PublikacjaOne of the first books to cover transformation products, rather than primary compounds, Transformation Products of Emerging Contaminants in the Environment gathers, specifies, synthesizes, and advances existing knowledge of the most important transformation product (TPs) of the main groups of emerging contaminants with potential concern to human health and the environment. This two-volume set for researchers and professionals covers...
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Mechanism-based inactivation of human cytochrome P450 1A2 and 3A4 isoenzymes by antitumor triazoloacridinone C-1305.
Publikacja5-Dimethylaminopropylamino-8-hydroxytriazoloacridinone, C-1305, is a promising antitumor therapeutic agent with high activity against several experimental tumors. It was determined to be a potent and selective inhibitor of liver microsomal and human recombinant cytochrome P450 (CYP) 1A2 and 3A4 isoenzymes. Therefore, C-1305 might modulate the effectiveness of other drugs used in multidrug therapy. The objective of this study was...
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Unstability of 4-CMC in human serum specimen
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Rare-earth elements in human colostrum milk
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Human Preference Modelling in Usability of Graphical Interfaces
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