Wyszukiwarka
Filtry
wszystkich: 2105
-
Katalog
wyświetlamy 1000 najlepszych wyników Pomoc
Wyniki wyszukiwania dla: LYME DISEASE, BORRELIA BURGDORFERI SENSU LATO, EPITOPE MAPPING, SERODIAGNOSIS, CHIMERIC PROTEINS
-
Research in Plant Disease
Czasopisma -
New Disease Reports
Czasopisma -
Infectious Disease Modelling
Czasopisma -
ARCHIVES OF DISEASE IN CHILDHOOD
Czasopisma -
Transplant Infectious Disease
Czasopisma -
SEMINARS IN LIVER DISEASE
Czasopisma -
Pharmacokinetics and Pharmacodynamics of a Chimeric/Humanized Anti-CD3 Monoclonal Antibody, Otelixizumab (TRX4), in Subjects With Psoriasis and With Type 1 Diabetes Mellitus
Publikacja -
Circular Dichroism Imaging: Mapping the Local Supramolecular Order in Thin Films of Chiral Functional Polymers
Publikacja -
Flooding Extent Mapping for Synthetic Aperture Radar Time Series Using River Gauge Observations
PublikacjaThe flooding extent area in a river valley is related to river gauge observations such as discharge and water elevations. The higher the water elevations, or discharge, the larger the flooding area. Flooding extent maps are often derived from synthetic aperture radar (SAR) images using thresholding methods. The thresholding methods vary in complexity and number of required parameters. We proposed a simple thresholding method that...
-
Data regarding a new, vector-enzymatic DNA fragment amplification-expression technology for the construction of artificial, concatemeric DNA, RNA and proteins, as well as biological effects of selected polypeptides obtained using this method
PublikacjaApplications of bioactive peptides and polypeptides are emerging in areas such as drug development and drug delivery systems. These compounds are bioactive, biocompatible and represent a wide range of chemical properties, enabling further adjustments of obtained biomaterials. However, delivering large quantities of peptide derivatives is still challenging. Several methods have been developed for the production of concatemers –...
-
A new human IgG avidity test, using mixtures of recombinant antigens (rROP1, rSAG2, rGRA6), for the diagnosis of difficult-to-identify phases of toxoplasmosis
PublikacjaThe preliminary diagnostic utility of two mixtures of Toxoplasma gondii recombinant antigens (rROP1+rSAG2 and rROP1+rGRA6) in IgG ELISA and IgG avidity test has been evaluated. A total of 173 serum samples from patients with toxoplasmosis and seronegative people were examined. The sensitivity of IgG ELISA for rROP1+rSAG2 and rROP1+rGRA6 was 91.1% and 76.7%, respectively, while the reactivity for sera from patients where acute toxoplasmosis...
-
The Extracellular Bacterial HtrA Proteins as Potential Therapeutic Targets and Vaccine Candidates
Publikacja -
Evolution of physics-based methodology for exploring the conformational energy landscape of proteins
Publikacja -
Generalization of the Elastic Network Model for the Study of Large Conformational Changes in Proteins
Publikacja -
Porcine myofibrillar proteins as potential precursors of bioactive peptides – an in silico study
Publikacja -
Analysis of differences in the stability of proteins encoded in mitochondrial DNA of model organisms
Publikacja -
Effect of buckwheat flour on microelements and proteins contents in gluten-free bread
Publikacja -
Partial characterization of proteins from mussel Mytilus galloprovincialis as a biomarker of contamination
PublikacjaPrzedmiotem zainteresowania były:- funkcjonalne i przeciwutleniające właściwości białek małża Mytilus galloprovincialis,- poziom zawartości metali ciężkich (ołów i kadm) w tkankach.Badania przeprowadzono dla małży zebranych zarówno w zanieczyszczonych, jak i w czystych obszarach strefy brzegowej Morza Czarnego w regionie Warny (Bułgaria). W badaniach wykorzystano takie techniki analityczne jak: spektroskopia FTIR, fluorescencja,...
-
Coarse-grained simulation - an efficient approach for studying motions of large proteins
PublikacjaOne of the most important challenges in performing Molecular Dynamics (MD) simulations of large protein complexes is to accommodate the model accuracy and the simulation timescale. Hitherto, for the most relevant dynamics of protein aggregates in an explicit aqueous environment, the timescale reachable for the all-atoms simulations is of hundreds of nanoseconds. This range is four to six orders of magnitude smaller than processes...
-
Design, synthesis and biological evaluation of novel N-phosphorylated and O-phosphorylated tacrine derivatives as potential drugs against Alzheimer’s disease
PublikacjaIn this work, we designed, synthesised and biologically investigated a novel series of 14N- and O-phosphorylated tacrine derivatives as potential anti-Alzheimer’s disease agents. In the reaction of 9-chlorotacrine and corresponding diamines/aminoalkylalcohol we obtained diamino and aminoalkylhydroxy tacrine derivatives. Next, the compounds were acid to give final products 6–13 and 16–21 that were characterised by 1H, 13 C, 31P...
-
Risk factors for chronic kidney disease do not influence the serum levels of asymmetric dimethylarginine in HIV-1-infected patients without significant renal disease
Publikacja -
Frequently updated noise threat maps created with use of supercomputing grid
PublikacjaAn innovative supercomputing grid services devoted to noise threat evaluation were presented. The services described in this paper concern two issues, first is related to the noise mapping, while the second one focuses on assessment of the noise dose and its influence on the human hearing system. The discussed services were developed within the PL-Grid Plus Infrastructure which accumulates Polish academic supercomputer centers....
-
Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease
Publikacja -
Circulating suPAR as a biomarker of disease severity in children with proteinuric glomerulonephritis
Publikacja -
The effect of cigarette smoking on the clinical course of inflammatory bowel disease
Publikacja -
Population pharmacokinetics of hydroxyurea for children and adolescents with sickle cell disease
Publikacja -
Caring for patients with Huntington disease – A survey of caregivers’ experiences and views
Publikacja -
Are advanced glycation end-products specific biomarkers for Alzheimer's disease?
Publikacja -
Nicotinamide phosphoribosyltransferase expression in thyroid glands of patients with Graves' disease
Publikacja -
The atherosclerotic heart disease and protecting properties of garlic: contemporary data
PublikacjaArtykuł jest pracą przeglądową zawierającą najnowsze dane dotyczące choroby serca w przebiegu miażdżycowym oraz ochonnych właściwości czosnku. Obecnie prowadzone badania wykazały fundamentalną rolę jaką odgrywa czosnek we wszystkich stadiach choroby. Liczne badania in-vitro potwierdzają zdolność czosnku do redukcji parametrów zachorowania na choroby serca w przebiegu miażdżycy: całkowity cholesterol, LDL, trigliceryny, utlenione...
-
Vitamin D receptor gene polymorphisms in Alzheimer's disease patients
Publikacja -
Parkinson’s disease: Etiopathogenesis, molecular basis and potential treatment opportunities
Publikacja -
Demodicosis as an opportunistic infection in a patient with Crohn’s disease treated with infliximab
Publikacja -
The polypill: an emerging treatment alternative for secondary prevention of cardiovascular disease
Publikacja -
Hypertension and coronary artery disease: Mechanistic insights and therapeutic challenges
Publikacja -
Thyroid Peroxidase as an Autoantigen in Hashimoto’s Disease: Structure, Function, and Antigenicity
Publikacja -
Definitions of health and disease among physicians and Społem PSS employees
Publikacja -
Family caregivers’ experiences with healthcare services: a case of Huntington disease
Publikacja -
B13 Can Dna Methylation Be A Factor In The Pathogenesis Of Huntington's Disease?
Publikacja -
Pathologic bone alterations in celiac disease: Etiology, epidemiology, and treatment
Publikacja -
A New Technique of Spine Disease Treatment Supported by ADRSK1 Device
Publikacja -
Evaluation of Selenium Concentrations in Patients with Crohn’s Disease and Ulcerative Colitis
Publikacja -
Visual control improves the accuracy of hand positioning in Huntington’s disease
Publikacja -
Nieniszczące Metody Badań Konstrukcji Metalowych 2022/23 lato
Kursy OnlineKurs przeznaczony dla studentów 8 sem. studiów inżynierskich niestacjonarnych w roku akademickim 2022/2023 lato
-
Teledetekcja 2023/2024 (lato)
Kursy OnlineTeledetekcja 2023/2024 (lato), kurs wspierający przedmiot Teledetekcja, PG_00044813, przeznaczony dla studentów: Kierunek studiów: Geodezja i Kartografia Poziom kształcenia: I stopnia - inżynierskie Rok akademicki realizacji przedmiotu: 2023/2024Forma studiów: stacjonarne Rok studiów: 2 Semestr: 4 (letni)
-
Protective and risk factors of cognitive decline and dementia with a special emphasis on social health: A systematic mapping review
Publikacja -
Intraoperative, Radio-Guided Sentinel Lymph Node Mapping in 110 Nonsmall Cell Lung Cancer Patients
Publikacja -
Blue-dye intraoperative sentinel lymph node mapping in early non-small cell lung cancer
Publikacja -
Mapping the Structural and Dynamic Determinants of pH-Sensitive Heparin Binding to Granulocyte Macrophage Colony Stimulating Factor
PublikacjaGranulocyte macrophage colony stimulating factor (GMCSF) is an immunomodulatory cytokine that is harnessed as a therapeutic. GMCSF is known to interact with other clinically important molecules, such as heparin, suggesting that endogenous and administered GMCSF has the potential to modulate orthogonal treatment outcomes. Thus, molecular level characterization of GMCSF and its interactions with biologically active compounds is critical...
-
Mapping the Transglycosylation Relevant Sites of Cold-Adapted β-D-Galactosidase from Arthrobacter sp. 32cB
PublikacjaB-Galactosidase from Arthrobacter sp. 32cB (ArthbetaDG) is a cold-adapted enzyme able to catalyze hydrolysis of beta-D-galactosides and transglycosylation reaction, where galactosyl moiety is being transferred onto an acceptor larger than a water molecule. Mutants of ArthbetaDG D207A and E517Q were designed to determine the significance of specific residues and to enable formation of complexes with lactulose and sucrose and to...