Filtry
wszystkich: 154
Wyniki wyszukiwania dla: PHASE TRANSFORMATIONS
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Modeling and Accuracy Assessment of Determining the Coastline Course Using Geodetic, Photogrammetric and Satellite Measurement Methods: Case Study in Gdynia Beach in Poland
PublikacjaThe coastal environment represents a resource from both a natural and economic point of view, but it is subject to continuous transformations due to climate change, human activities, and natural risks. Remote sensing techniques have enormous potential in monitoring coastal areas. However, one of the main tasks is accurately identifying the boundary between waterbodies such as oceans, seas, lakes or rivers, and the land surface....
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Electrochemical and in silico approaches for liver metabolic oxidation of antitumor-active triazoloacridinone C -1305
Publikacja5-Dimethylaminopropylamino-8-hydroxytriazoloacridinone (C-1305) is a promising antitumor compound developed in our laboratory. A better understanding of its metabolic transformations is still needed to explain the multidirectional mechanism of pharmacological action of triazoloacridinone derivatives at all. Thus, the aim of the current work was to predict oxidative pathways of C-1305 that would reflect its phase I metabolism. The...
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Electrochemical simulation of enzymatic transformations studied for the selected antitumor acridine derivatives
PublikacjaThe elucidation of the metabolic pathways and the biotransformation mechanisms of potential drugs is a crucial point in drug development. It allows to know the activation routes of the new biologically active compounds, especially in respect to their possible toxicity. Generally, in vivo or in vitro experiments with liver microsomes or hepatocytes are performed. However, these testing schemes are tedious, time consuming and of...
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Vision of the development of transformations in the district – Lower Sopot (Dolny Sopot) district case study, study proposal no 6, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 6, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located in Lower...
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Vision of the development of transformations in the district – Gdańsk-Lower City (Dolne Miasto) district case study, study proposal no 2, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Gdańsk-Lower City (Dolne Miasto) district, study proposal no 2, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located...
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Vision of the development of transformations in the district – Gdańsk-Lower City (Dolne Miasto) district case study, study proposal no 1, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Gdańsk-Lower City (Dolne Miasto) district, study proposal no 1, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located...
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Vision of the development of transformations in the district – Gdańsk-Lower City (Dolne Miasto) district case study, study proposal no 3, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Gdańsk-Lower City (Dolne Miasto) district, study proposal no 3, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located...
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Vision of the development of transformations in the district – Lower Sopot (Dolny Sopot) district case study, study proposal no 1, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 1, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located in Lower...
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Vision of the development of transformations in the district – Lower Sopot (Dolny Sopot) district case study, study proposal no 3, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 3, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located in Lower...
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Vision of the development of transformations in the district – Lower Sopot (Dolny Sopot) district case study, study proposal no 4, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 4, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located in Lower...
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Vision of the development of transformations in the district – Lower Sopot (Dolny Sopot) district case study, study proposal no 2, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 2, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located in Lower...
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Vision of the development of transformations in the district – Lower Sopot (Dolny Sopot) district case study, study proposal no 5, April 2021
Dane BadawczeThe data presents results of work within the studies of the vision of the district in the context of the city, Lower Sopot (Dolny Sopot) district, study proposal no 5, from April 2021. The goal of the research process was to present the future image of the neighborhood and initial ideas of the development of transformations of the area located in Lower...
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Novel insights into conjugation of antitumor-active unsymmetrical bisacridine C-2028 with glutathione: characteristics of non-enzymatic and glutathione S-transferase-mediated reactions
PublikacjaUnsymmetrical bisacridines (UAs) are a novel potent class of antitumor-active therapeutics. A significant route of phase II drug metabolism is conjugation with glutathione (GSH), which can be non-enzymatic and/or catalyzed by GSH-dependent enzymes. The aim of this work was to investigate the GSH-mediated metabolic pathway of a representative UA, C 2028. GSH supplemented incubations of C-2028 with rat, but not with human, liver...
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Electrochemical simulation of metabolism for antitumor-active imidazoacridinone C-1311 and in silico prediction of drug metabolic reactions
PublikacjaThe metabolism of antitumor-active 5-diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) has been investigated widely over the last decade but some aspects of molecular mechanisms of its metabolic transformation are still not explained. In the current work, we have reported a direct and rapid analytical tool for better prediction of C-1311 metabolism which is based on electrochemistry (EC) coupled on-line with electrospray...
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Eigenfaces, Fisherfaces, Laplacianfaces, Marginfaces – How to Face the Face Verification Task
PublikacjaThis paper describes the exhaustive tests of four known methods of linear transformations (Eigenfaces, Fisherfaces, Laplacianfaces and Marginfaces) in the context of face verification task. Additionally, we introduce a new variant of the transformation (Laplacianface + LDA), and the specific interval-based decision rule. Both of them improve the performance of face verification, in general, however, our experiments show that the...
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L'Italie. Gagner à tout prix. L'industrie de l'armenent italien pendant la Grande Guerre
PublikacjaThe chapter outlines the economic and technological transformations of the Italian armament industry during the First World War
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Integrable zero-range potentials in a plane
PublikacjaWe examine general statements in the Wronskian representation of Darboux transformations for plane zero-range potentials. Such expressions naturally contain scattering problem solution. We also apply Abel theorem to Wronskians for differential equations and link it to chain equations for Darboux transforms to fix conditions for further development of the underlying distribution concept. Moutard transformations give a convenient...
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Mentor & Student Reserch Lab
PublikacjaRelacja z realizacji projektów badawczych przygotowanych w ramach Mentor&Student Research Lab - Urban Transformations 2014
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Effect of microstructure on mechanical properties and corrosion resistance of 2205 duplex stainless steel
PublikacjaThis paper presents results of the research on impact of microstructure of austenitic-ferritic steel of duplex type on its mechanical properties and susceptibility to stress corrosion cracking. As showed, improper processing technologies more and more often used in shipbuilding industry for plates and other half-finished products made of duplex steel may cause significant lowering their properties, which frequently makes their...
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Revealing dynamic changes of the volatile profile of food samples using PTR–MS
PublikacjaVolatile compounds carry valuable information regarding the properties of foodstuffs. Volatiles emitted from food can be used as, for example, indicators of quality, shelf-life, or authenticity. A better understanding of the multitude of transformations which occur during food processing could facilitate the optimisation of production, increase the desirability of food products, and also their wholesomeness. However, as some of...