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Wyniki wyszukiwania dla: THERAPEUTIC GARDEN
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Therapeutic biomaterials - application in neurology and cardiology
PublikacjaBiomaterials are of interest in most medical fields. It's hard to imagine life without them. And due to the ever-increasing demand, scientists are developing new materials. Diseases of the nervous and cardiovascular systems are still a big problem, which are associated with a limited ability to regenerate brain or heart tissues. Therefore, this review discusses the advancement in biomaterial engineering for the treatment of neurological...
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Therapeutic biomaterials – application in neurology and cardiology
PublikacjaBiomaterials are of interest in most medical fields. It's hard to imagine life without them. And due to the ever-increasing demand, scientists are developing new materials. Diseases of the nervous and cardiovascular systems are still a big problem, which are associated with a limited ability to regenerate brain or heart tissues. Therefore, this review discusses the advancement in biomaterial engineering for the treatment of neurological...
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CDK9: Therapeutic Perspective in HCC Therapy
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Therapeutic Potential of Multifunctional Tacrine Analogues
PublikacjaTacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model inhibitor of cholinesterases in the therapy of Alzheimer’s disease. The interest in these compounds is mainly related to a high variety of their structure and biological properties. In the present review, we...
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Therapeutic potential of adenosine analogues and conjugates
PublikacjaZaprezentowano przegląd literatury chemicznej na temat analogów i koniugatów adenozyny oraz ich potencjalne zastosowanie terapeutyczne. Zwrócono także uwagę na ich oddziaływanie z receptorami adenozyny.
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Phosphoroorganic Metal Complexes in Therapeutics
PublikacjaThe present mini-review highlights recent developments on antitumor activity of metal-based therapeutics which have been a subject of researches for the last few decades. In 1965, Rosenberg found that during an electrolysis on platinum electrodes a complex of Pt is generated which inhibited to a great extent a binary fission in Escherichia coli bacteria. This discovery started a new chapter in medicinal chemistry and the interesting...
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mTOR Signaling and Potential Therapeutic Targeting in Meningioma
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Urban design and therapeutic landscapes. Evolving theme.
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Therapeutic Potential of Multifunctional Derivatives of Cholinesterase Inhibitors
PublikacjaThe aim of this work is review of tacrine analogues from the last three years, which were not included in the latest review work, donepezil and galantamine hybrids from 2015 and rivastigmine derivatives from 2014. In this account we summarize the efforts toward the development and characterization of non-toxic inhibitors of cholinesterases based on mentioned drugs with various interesting additional properties such as antioxidant,...
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Photoinactivation of ESKAPE pathogens: overview of novel therapeutic strategy
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In vitro evaluation of novel lipopeptides with potential therapeutic application
PublikacjaThe synthesis of derivatives of Gly-His-Lys was elaborated followed by their antimicrobial activity investigation.
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Therapeutic targeting of cathepsin C: from pathophysiology to treatment
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Quality monitoring of therapeutic processes in small treatment center for children
PublikacjaW artykule przedstawiono specyfikę oraz opis zasad nadzorowania procesów terapeutycznych w ramach systemu zarzadzania jakością w małej placówce służby zdrowia.
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CRL4CRBN E3 Ligase Complex as a Therapeutic Target in Multiple Myeloma
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Ginger (<i>Zingiber officinale</i>) – a spice with therapeutic properties
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Delving into the Therapeutic Potential of Carica papaya Leaf against Thrombocytopenia
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Conjugate of Enkephalin and Temporin Peptides as a Novel Therapeutic Agent for Sepsis
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Neuroinflammation in Dementia—Therapeutic Directions in a COVID-19 Pandemic Setting
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Hypertension and coronary artery disease: Mechanistic insights and therapeutic challenges
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The effectiveness of therapeutic massage in neck pain – prospective, preliminary studies
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Therapeutic Potential of Carnosine and Its Derivatives in the Treatment of Human Diseases
PublikacjaDespite significant progress in the pathogenesis, diagnosis, treatment, and prevention of cancer and neurodegenerative diseases, their occurrence and mortality are still high around theworld. The resistance of cancer cells to the drugs remains a significant problem in oncology today,while in the case of neuro-degenerative diseases, therapies reversing the process are still yet to be found. Furthermore, it is important to seek new...
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Renal nerve ablation: Emerging role in therapeutics
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Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions
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The Extracellular Bacterial HtrA Proteins as Potential Therapeutic Targets and Vaccine Candidates
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Poland: Quality Monitoring of Therapeutic Processes in a Small Treatment Center for Children
PublikacjaThis article presents the case of the first ISO 9001:2000-certified small healthcare organization (the Center for Therapy and Rehabilitation) providing therapeutic and rehabilitation services for disabled children in Northern Poland. Elements of the process-oriented healthcare quality system implementation, initial benefits, and the organization's quality system structure and process descriptions are described. Particular attention...
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New vitamin D analogs as potential therapeutics in melanoma
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SENSORY GARDENS INCLUSIVELY DESIGNED FOR VISUALLY IMPAIRED USERS.
PublikacjaThis paper discusses the design of sensory gardens, created especially to provide for the needs of sight impaired children and youth. These gardens should be inclusively available to general public. A sensory garden may have both therapeutic and educational effects. The research findings concerning therapeutic effects of contact with nature on children and youth are reviewed. The design problems related to providing a space for...
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Od garden city do ecocity
PublikacjaArtykuł omawia wybrane wątki ewolucji aspektów środowiskowych miasta w okresie od Garden City do czasów obecnych, omawiając narodziny, rozwój i ideę współczesnego miasta. Rozważania obejmują kolejno genezę i istotę miasta-ogrodu, jednostki sąsiedzkiej, modernizmu, postmodernizmu, nowego urbanizmu, oraz analizę współczesnych idei naprawy miast, zawartych w rozmaitych dokumentach, systemach certyfikacji, pozycjach literaturowych,...
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublikacjaPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
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Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets
PublikacjaNitric oxide (NO) is one of the most important molecules released by endothelial cells, and its antiatherogenic properties support cardiovascular homeostasis. Diminished NO bioavailability is a common hallmark of endothelial dysfunction underlying the patho‑ genesis of the cardiovascular disease. Vascular NO is synthesized by endothelial nitric oxide synthase (eNOS) from the substrate L‑arginine (L‑Arg), with tetrahydrobiopterin...
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Mapping Mechanostable Pulling Geometries of a Therapeutic Anticalin/CTLA-4 Protein Complex
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Neuroprotective Effects of Cannabidiol in Hypoxic Ischemic Insult. The Therapeutic Window in Newborn Mice
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Myeloid-derived suppressor cells (MDSCs) in brain cancer: challenges and therapeutic strategies
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Therapeutic Qualities and Sustainable Approach to Heritage of the City. The Coastal Strip in Gdańsk, Poland
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Isolation and Characterization of NP-POL Nonapeptide for Possible Therapeutic Use in Parkinson’s Disease
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Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics
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Blood pressure variability: Emerging role in risk assessment and therapeutics
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Current state of a dual behaviour of antimicrobial peptides-Therapeutic agents and promising delivery vectors
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Aptamer based tools for environmental and therapeutic monitoring: A review of developments, applications, future perspectives
PublikacjaNucleic acids in the form of aptamers play a growing and significant role in the targeted and rapid analysis of environmental sample composition and medical analyses. In this paper, the review of both aptamers synthesis methods as well as application of these short chain oligonucleotides (with critical comments on their strong and weak features) are given. The first ones include: systematic evolution of ligands by exponential enrichment...
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Role of Myeloid-derived suppressor cell (MDSC) in autoimmunity and its potential as a therapeutic target
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Research, theories and practical experience of therapeutic landscapes as a tool for urban open space design
PublikacjaThis paper reviews the research on therapeutic landscapes and discusses the design of urban parks and open green space. Firstly, the most relevant research on therapeutic landscapes is reviewed. Secondly, the practical experience of healing and therapeutic gardens is discussed. Finally, the conclusions leading to future use of therapeutic landscape concept in urban open space design are presented.
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Assessment of Therapeutic Progress After Acquired Brain Injury Employing Electroencephalography and Autoencoder Neural Networks
PublikacjaA method developed for parametrization of EEG signals gathered from participants with acquired brain injuries is shown. Signals were recorded during therapeutic session consisting of a series of computer assisted exercises. Data acquisition was performed in a neurorehabilitation center located in Poland. The presented method may be used for comparing the performance of subjects with acquired brain injuries (ABI) who are involved...
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Positive results of serological tests for syphilis in pregnancy – diagnostic and therapeutic problems, report of two cases
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Angiotensin receptor - neprilysin inhibiton (ARNI) – A novel therapeutic concept for management of hypertension and heart failure
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Green Therapy w projektowaniu ośrodków medycznych Green Therapy in complex design of health centres
PublikacjaKoncepcja przestrzenna ogrodu terapeutycznego podporządkowana jest generalnej idei otwierania się projektantów na poszukiwanie nowych możliwości poprawy samopoczucia odbiorcy - poprzez zapewnienie użytkownikom poczucia bezpieczeństwa, komfortu i odprężenia, harmonii. Dotyczy to nie tylko grupy osób chorych, które dręczone są przez niepokoje i napięcia wywołane przez niepełnosprawność czy chorobę, ale także pacjentów w różnym wieku...
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Abdominoplasty Skin-Based Dressing for Deep Wound Treatment—Evaluation of Different Methods of Preparation on Therapeutic Potential
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Hepatitis D, B and C virus (HDV/HBV/HCV) coinfection as a diagnostic problem and therapeutic challenge
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Applications of Cannabis Sativa L. in Food and Its Therapeutic Potential: From a Prohibited Drug to a Nutritional Supplement
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Assessing therapeutic relevance of biologically interesting, ampholytic substances based on their physicochemical and spectral characteristics with chemometric tools
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Novel chalcone-derived pyrazoles as potential therapeutic agents for the treatment of non-small cell lung cancer
PublikacjaLung cancer is considered to account for approximately one-fifth of all malignant tumor-related deaths worldwide and is therefore one of the most lethal malignancies. Pyrazole scaffold possesses a wide range of biological and pharmacological activities, which play important roles in medicinal chemistry. The present study reports the synthesis and in vitro biological characterization of nine pyrazoles derived from chalcones as potential...