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Wyniki wyszukiwania dla: therapeutic landscapes
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Isolation and Characterization of NP-POL Nonapeptide for Possible Therapeutic Use in Parkinson’s Disease
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Purinergic implication in amyotrophic lateral sclerosis—from pathological mechanisms to therapeutic perspectives
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Therapeutic Qualities and Sustainable Approach to Heritage of the City. The Coastal Strip in Gdańsk, Poland
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Mapping Mechanostable Pulling Geometries of a Therapeutic Anticalin/CTLA-4 Protein Complex
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Endothelial dysfunction due to eNOS uncoupling: molecular mechanisms as potential therapeutic targets
PublikacjaNitric oxide (NO) is one of the most important molecules released by endothelial cells, and its antiatherogenic properties support cardiovascular homeostasis. Diminished NO bioavailability is a common hallmark of endothelial dysfunction underlying the patho‑ genesis of the cardiovascular disease. Vascular NO is synthesized by endothelial nitric oxide synthase (eNOS) from the substrate L‑arginine (L‑Arg), with tetrahydrobiopterin...
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublikacjaPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
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Nonsense-Mediated mRNA Decay: Pathologies and the Potential for Novel Therapeutics
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Blood pressure variability: Emerging role in risk assessment and therapeutics
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Developing a Framework for the Implementation of Landscape and Greenspace Indicators in Sustainable Urban Planning. Waterfront Landscape Management: Case Studies in Gdańsk, Poznań and Bristol
PublikacjaUrban landscape (UL) management and urban greenspace (UG) delivery require effective planning tools. The aim of the study is to develop a conceptual framework for the implementation of ecological, structural and visual landscape and greenspace indicators (LGI) in spatial development of urban areas. The UL and UG management provisions in Poland are identified at various levels of urban planning (local, municipal and regional). Furthermore,...
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Regulation of Plant Microprocessor Function in Shaping microRNA Landscape
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Landscape of the Vistula Estuary - searching for traces of ingenium embodied
PublikacjaArtykuł podaje skrótowe informacje o dawnym i współczesnym znaczeniu obiektów inżynieryjnych w krajobrazie delty Wisły, które znalazły się na trasie objazdu konserwatorskiego w dniu 5 maja w ramach realizacji programu konferencji HOT-GO 4 wraz z kalendarium ich dziejów: Most Lisewski przez Wisłę w Tczewie, wielki przekop Wisły w Świbnie, śluzy w Przegalinie, Gdańskiej Głowie i Białej Górze, relikty kanału w Piekle.
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Rural Landscape Planning for Sustainable Development. The Case of Poland
PublikacjaThis text results from theoretical study on the possibilities of rural landscape renovation in Poland. The introduction marks new spatial phenomena and the scope of their influence. It indicates social and cultural reasons of the changes, and states the need of their renewed interpretation. The second part of the article contains a description of the degrading cultural landscape of the country and presents its features. It then...
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The dynamic Polish suburban landscape created by SME sector
PublikacjaWspółcześnie zaobserwować można dynamiczne przeobrażenia przestrzeni wokół miast polegające na przemieszczaniu się ludności i podmiotów gospodarczych z miasta centralnego do strefy podmiejskiej. Wydaje się, że charakterystycznym elementem krajobrazu polskich obszarów podmiejskich jest duża ilość działających w nich przedsiębiorstw sektora MSP.
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Landscape as the tool of coherence in the land management of rural communes
PublikacjaEconomic and social transformation of rural areas in Poland after 1990 reveals itself through disintegration of previous spatial order. Building a new pattern requires a vision, which would counteract complex causes of disintegration. The latter belong to institutional domain of planning strategies and the area of common practices. Therefore, agreement on aims and means between spatial policy strategies and tactics of space users...
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CLINICA TERAPEUTICA
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HEALTH-AFFIRMING EVERYDAY LANDSCAPES IN SUSTAINABLE CITY. ECO-NEIGHBORHOODS IN FRANCE CASE
PublikacjaThis paper discusses the close relationship between the concept of health-affirming everyday landscapesand the idea of sustainable city design.The French National program of eco-neighborhood certification ÉcoQuartier is described and the correlation between the concepts of health-affirming landscapes,sustainable cities, and eco-neighborhoods is explained using the example of a selected eco-neighborhood in France.
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Role of Myeloid-derived suppressor cell (MDSC) in autoimmunity and its potential as a therapeutic target
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Targeting mTORs by omega-3 fatty acids: A possible novel therapeutic strategy for neurodegeneration?
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CEACAM6 as a Novel Therapeutic Target to Boost HO-1—mediated Antioxidant Defense in COPD
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Current state of a dual behaviour of antimicrobial peptides-Therapeutic agents and promising delivery vectors
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Aptamer based tools for environmental and therapeutic monitoring: A review of developments, applications, future perspectives
PublikacjaNucleic acids in the form of aptamers play a growing and significant role in the targeted and rapid analysis of environmental sample composition and medical analyses. In this paper, the review of both aptamers synthesis methods as well as application of these short chain oligonucleotides (with critical comments on their strong and weak features) are given. The first ones include: systematic evolution of ligands by exponential enrichment...
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CLINICAL PHARMACOLOGY & THERAPEUTICS
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Diabetes Technology & Therapeutics
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Cardiovascular Intervention and Therapeutics
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European Journal of Therapeutics
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Drug Discoveries and Therapeutics
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Nucleic Acid Therapeutics
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Drug and Therapeutics Bulletin
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Oral Therapeutics and Pharmacology
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ALIMENTARY PHARMACOLOGY & THERAPEUTICS
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Japanese Pharmacology and Therapeutics
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Clinical Neuropsychopharmacology and Therapeutics
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Journal of Phytomedicine and Therapeutics
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MOLECULAR CANCER THERAPEUTICS
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STUDIES IN THE HISTORY OF GARDENS & DESIGNED LANDSCAPES
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Rural Landscapes: Society, Environment, History
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Place attachment, place identity and aesthetic appraisal of urban landscape
PublikacjaAs the aesthetic of the Polish cities became a topic of wider discussions, it is important to detect the potentialrole of human-place relations. Two studies (N = 185 & N = 196) were conducted to explore the relationship betweenplace attachment, place identity and appraisal of urban landscape. Satisfaction with urban aesthetic was predicted by twodimensions of place attachment (place inherited and place...
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Effect of Newly Created Water Reservoirs on Agricultural Landscape Stability
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Impact of water reservoirs in Nienawiszcz on improve of the visual values of landscape
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Quality Structure of the Noctuidae Family in Selected Habitats of the Agricultural Landscape
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The landscape transformations of post-industrial areas based on selected examples
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Actual problems of the polish coastal landscape, architecture and culturalheritage protection
PublikacjaPraca zawiera ogólną charakterystykę krajobrazu polskiego wybrzeża, przedstawia podstawowe zagrożenia jako wartości wynikające z nieprzemyślanych decyzji planistycznych oraz żywiołowego rozwoju strefy nadmorskiej, prezentuje także walory środowiska kulturowego wsi położonych nad Bałtykiem, ich architekturę oraz aktualne problemy ich ochrony.
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The role of isolated farmsteads in the open landscape protection on the example of Kashubia
PublikacjaAs a result of the social and economic transformation of rural areas, open landscapes are disappearing. Former farmsteads are being devastated or beginning to lose their landscape context due to the spread of residential building development. At the same time, in many places, the farmstead form is clearly legible and remains an element with which the view is structured and enriched. The article was aimed at drawing attention to...
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Building culture written into the landscape – how to read spatial tradition
PublikacjaThe article presents a discussion on the experimenting with material leading to practical so-lutions in building structure in the context of the tradition of the place. It sketches out the practical aspects of creation of space while working with different local materials during the intensive workshops within the Structures in Building Culture IP programme. This kind of unique possibility to practice raw materials gives also the...
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Classification of Landscape Physiognomies in Rural Poland: The Case of the Municipality of Cekcyn
PublikacjaThis article presents a methodology and the results of the classification of the rural landscapes physiognomies conducted on the study area located in the municipality of Cekcyn, Poland. The study aimed to develop a landscape identification method that would combine natural, cultural, and visual criteria with which to implement the provisions of the European Landscape Convention. The realization of the European Landscape Convention...
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Therapeutic Advances in Respiratory Disease
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Therapeutic Advances in Medical Oncology
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Therapeutic Innovation & Regulatory Science
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EXPERT OPINION ON THERAPEUTIC TARGETS
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Therapeutic Advances in Neurological Disorders
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