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Search results for: INFLAMMATORY BOWEL DISEASE
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Mitochondrial DNA copy number and trimethylamine levels in the blood: New insights on cardiovascular disease biomarkers
PublicationAmong cardiovascular disease (CVD) biomarkers, the mitochondrial DNA copy number (mtDNAcn) is a promising candidate. A growing attention has been also dedicated to trimethylamine-N-oxide (TMAO), an oxidative derivative of the gut metabolite trimethylamine (TMA). With the aim to identify biomarkers predictive of CVD, we investigated TMA, TMAO, and mtDNAcn in a population of 389 coronary artery disease...
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From the pills to environment – Prediction and tracking of non-steroidal anti-inflammatory drug concentrations in wastewater
PublicationThe extend of environment pollution by pharmaceuticals is in a stage that required more automatic and integrated solutions. The non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most popular pharmaceutical in the world and emerging pollutants of natural waters. The aim of the paper was to check the correlation of the sales data of selected NSAIDs (ibuprofen, naproxen, diclofenac) and their concentration in the WWTP...
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Depression and anxiety in cardiovascular disease
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Sleep disorders in Parkinson's disease
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Distinct characteristics of multisystem inflammatory syndrome in children in Poland
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3D Hand Shape Modeling for Automatic Assessing Motor Performance in Parkinson's Disease
PublicationIn this paper a method for hand pattern processing to create a 3D hand model is presented. By applying a complete hand armature to the model obtained, an interpolation of three motor tests for an individual Parkinson's disease patient can be performed. To obtain the 3D hand model the top view of the hand from a web cam is analyzed. The hand contour is examined to find characteristic points that allows for dividing hand image into...
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Analysis of Serum of Patients With Alzheimer’s Disease for the Level of Advanced Glycation End Products
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Long-term efficacy of 90Y-DOTATATE in patients with nonresectable pancreatic and small bowel neuroendocrine neoplasms
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Dynamic Modeling of COVID-19 Disease with Impact of Lockdown in Pakistan and Malaysia
PublicationBeing researchers, it is an utmost responsibility to provide insight on social issues thus, this work addresses the dynamic modeling of first and most contagious disease named as COVID-19 caused by coronavirus. The first case of COVID-19 appeared in Pakistan was on 26th February 2020 and in Malaysia on 27th February 2020; both patients had foreign travel history. In the paper, the number of total affected cases and total deaths...
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2-Methoxyestradiol and Hydrogen Peroxide as Promising Biomarkers in Parkinson’s Disease
PublicationEstrogens function in numerous physiological processes including controlling brain cell growth and differentiation. 2-Meth- oxestradiol (2-ME2), a 17β-estradiol (E2) metabolite, is known for its anticancer effects as observed both in vivo and in vitro. 2-ME2 affects all actively dividing cells, including neurons. The study aimed to determine whether 2-ME2 is a potentially cancer-protective or rather neurodegenerative agent in a...
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Supporting Gastroesophageal Reflux Disease Diagnostics by Using Wavelet Analysis in Esophageal pH-Metry
PublicationThis paper presents a new approach to computer supported esophageal pH-metry measurement analysis performed in order to diagnose gastroesophageal reflux disease. In this approach wavelet analysis was used to analyse the esophageal pH-metry course. The research was performed on three groups of pH-metry courses: whole 24-hour pH-metry course, sleep only pH-metry course and 20 minutes after the end of a meal pH-metry course. After...
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Detection of Alzheimer's disease using Otsu thresholding with tunicate swarm algorithm and deep belief network
PublicationIntroduction: Alzheimer’s Disease (AD) is a degenerative brain disorder characterized by cognitive and memory dysfunctions. The early detection of AD is necessary to reduce the mortality rate through slowing down its progression. The prevention and detection of AD is the emerging research topic for many researchers. The structural Magnetic Resonance Imaging (sMRI) is an extensively used imaging technique in detection of AD, because...
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Anti-inflammatory Activity and Phytochemical Profile of Galinsoga Parviflora Cav.
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Significance of selected inflammatory factors in metabolic disorders in association with psoriasis
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Vitamin D and its analogs as anticancer and anti-inflammatory agents
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Fever and Diarrhea as the Only Symptoms of Multisystem Inflammatory Syndrome in Children
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Guidelines for immunization of children following multisystem inflammatory syndrome in children
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Oxylipins in Plant Protection/Disease Management
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Kikuchi-Fujimoto disease: State of the art
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Markov Model of Disease Development and Recovery
PublicationMarkov models are commonly used to simulate diseases and allow modeling of multiple health states and outcomes. Starting with the well known Le Bras multistate model (cascading failure model) with time-independent transitions we will see how simple Markov mortality models may be pressed into the service of survival and event history analysis. We will focus on more complex models which will be able to take into account remission,...
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Influence of the electrosynthesis conditions on the spontaneous release of anti-inflammatory salicylate during degradation of polypyrrole coated iron for biodegradable cardiovascular stent
PublicationIn this work, the spontaneous release of anti-inflammatory salicylate from polypyrrole (PPy) coated iron has been studied during degradation of the material in phosphate buffer saline at 37 C. The sodium salicylate was incorporated into PPy in a one-step electropolymerization process. The influence of the synthesis conditions such as sodium salicylate concentration, pyrrole concentration and deposition charge on drug release profile...
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Analysis of exhaled breath for dengue disease detection by low-cost electronic nose system
PublicationThis paper presents a procedure and a set-up of an electronic nose system analyzing exhaled breath to detect the patients suffering from dengue – a mosquito-borne tropical disease. Low-power resistive gas sensors (MiCS-6814, TGS8100) were used to detect volatile organic compounds (VOCs) in the exhaled breath. The end-tidal phase of patients exhaled breath was collected with a BioVOCTM breath sampler. Two strategies were assessed...
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Investigating the disease- modifying properties of sclerotiorin in Alzheimer's therapy using acetylcholinesterase inhibition
PublicationAlzheimer's disease (AD) is a progressive neurodegenerative disorder caused due to the damage and loss of neurons in specific brain regions. It is the most common form of dementia observed in older people. The symptoms start with memory loss and gradually cause the inability to speak and do day-to-day activities. The cost of caring for those affected individuals is huge and is probably beyond most developing countries capability....
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Gender-Related Differences in Trimethylamine and Oxidative Blood Biomarkers in Cardiovascular Disease Patients
PublicationGender differences in the burden of cardiovascular disease (CVD) have been observed worldwide. In this study, plasmatic levels of trimethylamine (TMA) and blood oxidative biomarkers have been evaluated in 358 men (89 controls and 269 CVD patients) and 189 women (64 control and 125 CVD patients). The fluorescence technique was applied to determine erythrocyte membrane fluidity using 1,6-diphenyl-1,3,5-hexatriene (DPH) and Laurdan,...
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A pilot study with flow mediated skin fluorescence: A novel device to assess microvascular endothelial function in coronary artery disease
PublicationBackground: Endothelial dysfunction is one of the earliest vascular manifestations in the pathogenesis of cardiovascular disease. Noninvasive, simple and inexpensive methods of endothelial function assessment are therefore needed. Methods: Microvascular endothelial function was assessed in coronary artery disease (CAD) patients by flow mediated skin fluorescence (FMSF), based on measurements of NADH fluorescence intensity during...
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Physicochemical and Volatile Compounds Analysis of Fruit Wines Fermented with Saccharomyces cerevisiae: FTIR and Microscopy Study with Focus on Anti-Inflammatory Potential
PublicationThe growing trend in fruit wine production reflects consumers’ interest in novel, diverse drinking experiences and the increasing demand for healthier beverage options. Fruit wines made from kiwi, pomegranates, and persimmons fermented using S. bayanus Lalvin strain EC1118 demonstrate the versatility of winemaking techniques. Kiwifruit, persimmon, and pomegranate wines were analyzed using HPLC and GC-TOFMS analyses to determine...
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma—Recent Findings and Review
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Anti-inflammatory Potential of Flavonoids from the Aerial Parts of Corispermum marschallii
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Three episodes of Kawasaki disease including one after the Pneumo 23 vaccine in a child with a family history of Kawasaki disease
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Behçet’s Disease in a Polish Patient: A Case Report
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Diagnosis of preeclampsia in women with diabetic kidney disease
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Editorial(Hot Topic: Proteolysis in Health and Disease)
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Gastroesophageal Reflux Disease in Children with Cystic Fibrosis
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Different effect of smoking on genders in Crohn’s disease
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Arsenic causing gallbladder cancer disease in Bihar
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Pertussis: History of the Disease and Current Prevention Failure
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A subset of two adherence systems, acute pro-inflammatory pap genes and invasion coding dra, fim, or sfa, increases the risk of Escherichia coli translocation to the bloodstream
PublicationAn analysis of the phylogenetic distribution and virulence genes of Escherichia coli isolates which predispose this bacteria to translocate from the urinary tract to the bloodstream is presented. One-dimensional analysis indicated that the occurrence of P fimbriae and α-hemolysin coding genes is more frequent among the E. coli which cause bacteremia. However, a two-dimensional analysis revealed that a combination of genes coding...
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Trustworthy Applications of ML Algorithms in Medicine - Discussion and Preliminary Results for a Problem of Small Vessels Disease Diagnosis.
PublicationML algorithms are very effective tools for medical data analyzing, especially at image recognition. Although they cannot be considered as a stand-alone diagnostic tool, because it is a black-box, it can certainly be a medical support that minimize negative effect of human-factors. In high-risk domains, not only the correct diagnosis is important, but also the reasoning behind it. Therefore, it is important to focus on trustworthiness...
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Rivaroxaban protects from the oxysterol-induced damage and inflammatory activation of the vascular endothelium
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Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids
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Response of inflammatory cells to biodegradable ultra-fine grained Mg-based composites
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The Impact of Huntington Disease on Family Carers: a Literature Overview
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Tackling age-related disease: time for a step forward
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Pet Ownership and the Risk of Arterial Hypertension and Cardiovascular Disease
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The Global Burden of Disease Study 2015 and Blood Pressure
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Managing comorbid cardiovascular disease and sleep apnea with pharmacotherapy
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EDITORIALHypertension and cardiovascular disease: Is arterial stiffness the heart of the matter?
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Plasma Lipid Composition and Risk of Developing Cardiovascular Disease
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Estimation of Oxidative Stress Markers in Chronic Kidney Disease
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Exhaled nitric oxide in pediatric patients with respiratory disease
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