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Search results for: IMMUNOGLOBULIN-LIKE DOMAIN
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Novel approach to modeling spectral-domain optical coherence tomography with Monte Carlo method
PublicationNumerical modeling Optical Coherence Tomography (OCT) systems is needed for optical setup optimization, development of new signal processing methods and assessment of impact of different physical phenomena inside the sample on OCT signal. The Monte Carlo method has been often used for modeling Optical Coherence Tomography, as it is a well established tool for simulating light propagation in scattering media. However, in this method...
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Domain segmentation for low-cost surrogate-assisted multi-objective design optimisation of antennas
PublicationAbstract: Information regarding the best possible design trade-offs of an antenna structure can be obtained through multiobjective optimisation (MO). Unfortunately, MO is extremely challenging if full-wave electromagnetic (EM) simulation models are used for performance evaluation. Yet, for the majority of contemporary antennas, EM analysis is the only tool that ensures reliability. This study introduces a procedure for accelerated...
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Dithranol treatment of plaque-type psoriasis increases serum TNF-like weak inducer of apoptosis (TWEAK)
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Molecular basis for the bifunctional Uba4–Urm1 sulfur‐relay system in tRNA thiolation and ubiquitin‐like conjugation
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Non-Dioxin-Like PCBs – the Key Air Pollutant Associated with Lung Cancer in 15 Cities in Silesia
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Sandwich-like mesoporous silica flakes for anticancer drug transport—Synthesis, characterization and kinetics release study
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In vitro and in vivo evaluation of sandwich-like mesoporous silica nanoflakes as promising anticancer drug delivery system
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The cellulose fibers functionalized with star-like zinc oxide nanoparticles with boosted antibacterial performance for hygienic products
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Elimination of metal catalyst and carbon-like impurities from single-wall carbon nanotube raw material
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Slaughtered like animals. Revealing the atrocities committed by the Nazis on captives at Treblinka I by skeletal trauma analysis
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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MOF/TiO2 erythrocyte-like heterostructures decorated by noble metals for use in hydrogen photogeneration and pollutant photodegradation
PublicationVarious metal–organic framework (MOF)/TiO2 heterostructures can be obtained by the partial hydrolysis or calcination of Ti-based MOFs. By adjusting the hydrolysis and calcination steps of NH2-MIL-125 (Ti), a novel photoactive material composed of a MOF (NH2-MIL-125 (Ti)) and TiO2, with a unique “erythrocyte” shape, was developed. Furthermore, modification of the composition prepared by the partial hydrolysis of NH2- MIL-125 (Ti)...
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Structural change of carbon supported Pt nanocatalyst subjected to a step-like potential cycling in PEM FC
PublicationIn this paper we present detailed X-ray absorption fine structure (XAFS), X-ray diffraction (XRD) and transmission electron microscopy (TEM) investigations of the changes in the local geometric and electronic structure of Pt nanoparticles used as a cathode catalyst in proton exchange membrane fuel cell (PEMFC), working under controlled potential cycling conditions.
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Genetic and pharmacologic proteasome augmentation ameliorates Alzheimer’s-like pathology in mouse and fly APP overexpression models
PublicationThe proteasome has key roles in neuronal proteostasis, including the removal of misfolded and oxidized proteins, presynaptic protein turnover, and synaptic efficacy and plasticity. Proteasome dysfunction is a prominent feature of Alzheimer’s disease (AD). We show that prevention of proteasome dysfunction by genetic manipulation delays mortality, cell death, and cognitive deficits in fly and cell culture AD models. We developed...
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The effect of shear deformations' rotary inertia on the vibrating response of multi-physic composite beam-like actuators
PublicationIn consecutive studies on flexomagneticity (FM), this work investigates the flexomagnetic reaction of a vibrating squared multi-physic beam in finite dimensions. It is assumed that the bending and shear deformations cause rotary inertia. In the standard type of the Timoshenko beam the rotary inertia originated from shear deformations has been typically omitted. It means the rotary inertia resulting from shear deformation is a new...
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Young Shoots of White and Red Headed Cabbages Like Novel Sources of Glucosinolates as Well as Antioxidative Substances
PublicationMost literature data indicate that the diet rich in plant products reduces the risk of developing chronic non-communicable diseases and cancer. Brassica vegetables are almost exclusively synthesizing glucosinolates. Glucosinolates are higher in sprouts than in mature plants, being related to the activity of the specific myrosinase involved in the degradation of glucosinolates during developmental stages. This study compares the...
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A Simple Replica Method as the Way to Obtain a Morphologically and Mechanically Bone-like Iron-Based Biodegradable Material
PublicationPorous iron-based scaffolds were prepared by the simple replica method using polyurethane foam as a template and applying the sintering process in a tube furnace. Their surface morphology was characterized using scanning electron microscopy (SEM) and phase homogeneity was confirmed using X-ray diffraction (XRD). Corrosion behavior was determined using immersion and potentiodynamic polarization methods in phosphate buffered saline...
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Patch size setup and performance/cost trade-offs in multi-objective EM-driven antenna optimization using sequential domain patching
PublicationPurpose This paper aims to assess control parameter setup and its effect on computational cost and performance of deterministic procedures for multi-objective design optimization of expensive simulation models of antenna structures. Design/methodology/approach A deterministic algorithm for cost-efficient multi-objective optimization of antenna structures has been assessed. The algorithm constructs a patch connecting extreme Pareto-optimal...
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Individual contributions of M X-ray line from Cu- and Co-like tungsten ions and L X-ray line from Ne-like molybdenum ions – Benchmarks for new approach to determine the high-temperature tokamak plasma parameters
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Projection framework for hybrid methods derived from finite difference operators in time and frequency domain
PublicationW artykule przedstawiono ogólną koncepcję tworzenia algorytmów hybrydowych na bazie operatorowego sformułowania metody różnic skończonych. Wykorzystano koncepcję projekcji ortogonalnej w przestrzeni skończeniewymiarowej w celu modyfilacji pierwotnego sformułowania.
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Approximate analytical boundary conditions for efficient finite difference frequency domain simulations in cylindrical coordinates
PublicationW artykule zaprezentowano prostą technikę analizy rezonatora otwartego. Algorytm łączy w sobie metodę różnic skończonych i rozwinięć funkcyjnych , umożliwiając implementację warunków brzegowych symulujących otwartą przestrzeń. Metoda testowana była w analizie rezonatorów o różnych wymiarach,a otrzymane wyniki dobrze zgadzały się z rezultatami innych metod.
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Metrological characteristics of the flat voltammetric electrode in time domain with a reversible electrochemical reaction running on the surface
PublicationW artykule przedstawiono właściwości metrologiczne płaskich elektrod woltamperometrycznych. Omówiono wpływ napięcia polaryzującego na wartości parametrów charakteryzujących te elektrody.
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A frequency-domain surveillance of the robot's structural vibration with a use of modal control at energy performance index
PublicationRozważano drgania niestacjonarnego układu nośnego robota IRb-6. W celu nadzorowania drgań zastosowano algorytm sterowania modalnego przy energetycznym wskaźniku jakości w dziedzinie częstotliwości. Podejście takie umożliwia wykorzystanie elementów projektowania mechatronicznego do nadzorowania drgań, którego celem jest minimalizacja amplitudy drgań końcówek manipulacyjnych, a w konsekwencji - poprawa dokładności i powtarzalności...
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The structurally similar TRFH domain of TRF1 and TRF2 dimers shows distinct behaviour towards TIN2
PublicationThe telomere repeat binding-factor 1 and 2 (TRF1 and TRF2) proteins of the shelterin complex bind to duplex telomeric DNA as homodimers, and the homodimerization is mediated by their TRFH (TRF-homology) domains. We performed molecular dynamic (MD) simulations of the dimer forms of TRF1TRFH and TRF2TRFH in the presence/absence of the TIN2TBM (TIN2, TRF-interacting nuclear protein 2, TBM, TRF-binding motif) peptide. The MD results...
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Efficient Multiscale Finite Difference Frequency Domain Analysis Using Multiple Macromodels with Compressed Boundaries
PublicationW niniejszym artykule zaprezentowany został nowatorski pomysł na zmniejszenie numerycznej złożoności metody różnic skończonych przy użyciu wielu makromodeli. Skuteczność techniki macromodelingu zależy od liczby portów modelu. Aby zwiększyć efektywność algorytmu, próbki pola na granicy makromodeli są zastępowane przez amplitudy wielomianów Legendre'a. Przedefiniowanie problemu w taki sposób powoduje znaczną redukcję czasu analizy....
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Fabrication and characterization of a TiBs@MCN cable-like photocatalyst with high photocatalytic performance under visible light irradiation
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Correction: Slaughtered like animals. Revealing the atrocities committed by the Nazis on captives at Treblinka I by skeletal trauma analysis
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Application of SSB-like protein from Thermus aquaticus in multiplex PCR of human Y-STR markers identification
PublicationW tej publikacji prezentujemy zastosowanie białka SSB-podobnego Thermus aquaticus (TaqSSB) w reakcji multiplex PCR w celu identyfikacji markerów ludzkiego Y-STR. Wykorzystanie termostabilnego białka TaqSSB chroni lub redukuje tworzenie przez startery struktur dimerycznych, które powodują hamowanie hybrydyzacji starterów do badanego DNA i redukują ilość starterów dostępnych w reakcji PCR.
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Magnetizability of the relativistic hydrogen-like atom: applicayion of the Sturmian expansion of the first-order Dirac-Coulomb Green function
PublicationStosując rozwinięcie sturmowskie funkcji Greena-Diraca-Coulomba, znaleziono wyrażenie analityczne dla magnetyzowalności relatywistycznego atomu wodoro-podobnego w stanie podstawowym.
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Determining the optimal course alteration maneouvre in a multi-target encounter situation for a given ship domain model
PublicationW artykulee przedstawiono nową deterministyczną metodę wyznaczania niezbędnego manewru kursem dla sytuacji spotkania z wieloma obiektami obcymi i dla dowolnej zadanej domeny. Jej prostota i niska złożoność obliczeniowa czynią ją dobrą alternatywą dla obecnie stosowanych metod. Główny algorytm został przedstawiony wprost, tak aby mógł być bezpośrednio zastosowany w pokładowych systemach antykolizyjnych lub w systemach VTS.
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Multiple β-sheet molecular dynamics of amyloid formation from two ABl-SH3 domain peptides
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Globalized Knowledge-Based Simulation-Driven Antenna Miniaturization Using Domain-Confined Surrogates and Dimensionality Reduction
PublicationDesign of contemporary antenna systems encounters multifold challenges, one of which is a limited size. Compact antennas are indispensable for the new fields of application such as inter-net of things or 5G/6G mobile communication. Still, miniaturization generally undermines elec-trical and field performance. When attempted through numerical optimization, it turns into a constrained problem with costly constraints requiring electromagnetic...
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PTPRK Expression Is Downregulated in Drug Resistant Ovarian Cancer Cell Lines, and Especially in ALDH1A1 Positive CSCs-Like Populations
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Multimodal detection and analysis of a new type of advanced Heinz body-like aggregate (AHBA) and cytoskeleton deformation in human RBCs
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Enhanced photocatalytic activity of accordion-like layered Ti3C2 (MXene) coupled with Fe-modified decahedral anatase particles exposing {1 0 1} and {0 0 1} facets
PublicationNew composites consisting of decahedral anatase particles exposing {001} and {101} facets coupled with accordion-like layered Ti3C2 with boosted photocatalytic activity towards phenol and carbamazepine degradation were investigated. The photocatalysts were characterized with X-ray diffraction (XRD), diffuse reflectance spectroscopy (DR/UV–Vis), Brunauer-Emmett-Teller (BET) specific surface area, Raman spectroscopy, scanning electron...
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Multivalent Display of SARS-CoV-2 Spike (RBD Domain) of COVID-19 to Nanomaterial, Protein Ferritin Nanocages
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Crystallization and preliminary X-ray analysis of the isomerase domain of glucosamine-6-phosphate synthase from Candida albicans
PublicationSyntaza glukozamino-6-fosforanu (EC 2.6.1.16) katalizuje pierwszy, praktycznie nieodwracalny etap w szlaku biosyntezy heksozoamin, którego produktem końcowym jest UDP-GlcNAc, kluczowy substrat dla tworzenia ściany komórkowej drobnoustrojów. Otrzymano kryształy domeny izomerazowej syntazy GlcN-6-P z Candida albicans, składającej się z reszt 346-712 (42 kDa). Analiza rentgenograficzna kryształu wykazała, że należy on do grupy przestrzennej...
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Volterra series usefulness in modelling of the time-domain cross-talk phenomena in coupled microstrip lines with nonlinear termination
PublicationW pracy przedyskutowano możliwość wykorzystania szeregów Volterry do analizy zjawiska przesłuchu w sprzężonych liniach mikropaskowych z nieliniowym obciążeniem. Apracowano algorytm metody, zaś uzyskane wyniki numeryczne zweryfikowano poprzez porównania z wynikami badań eksperymentalnych linii obciążonych w torze transmisyjnym diodą Schottky'ego.
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Fast multi-objective design optimization of microwave and antenna structures using data-driven surrogates and domain segmentation
PublicationPurpose Strategies and algorithms for expedited design optimization of microwave and antenna structures in multi-objective setup are investigated. Design/methodology/approach Formulation of the multi-objective design problem oriented towards execution of the population-based metaheuristic algorithm within the segmented search space is investigated. Described algorithmic framework exploit variable fidelity modeling, physics- and...
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Analysis of impact of lossy audio compression on the robustness of watermark embedded in the DWT domain for non-blind copyright protection
PublicationA methodology of non-blind watermarking of the audio content is proposed. The outline of audio copyright problem and motivation for practical applications are discussed. The algorithmic theory pertaining watermarking techniques is briefly introduced. The system architecture together with employed workflows for embedding and extracting the watermarks are described. The implemented approach is described and obtained results are reported....
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Sulfanyl porphyrazines: Molecular barrel-like self-assembly in crystals, optical properties and in vitro photodynamic activity towards cancer cells
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Influence of narrowband ultraviolet B phototherapy on serum tumour necrosis factor-like weak inducer of apoptosis (TWEAK) in patients with psoriasis
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Does diclofenac act like a photosynthetic herbicide on green algae? Chlamydomonas reinhardtii synchronous culture-based study with atrazine as reference
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Synthesis and antimicrobial activity of truncated fragments and analogs of citropin 1.1: The solution structure of the SDS micelle-bound citropin-like peptides
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Effect of Washing on the Quality of Surimi-Like Preparation Obtained from Soft Tissue of Freshwater Mussel Sinanodonta woodiana (Lea, 1834)
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Derivation of Executable Test Models From Embedded System Models using Model Driven Architecture Artefacts - Automotive Domain
PublicationThe approach towards system engineering compliant to Model-Driven Architecture (MDA) implies an increased need for research on the automation of the model-based test generation. This applies especially to embedded real-time system development where safety critical requirements must be met by a system. The following paper presents a methodology to derive basic Simulink test models from Simulink system models so as to execute them...
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Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6
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Can mutations in the gene encoding transcription factor EKLF (Erythroid Krüppel-Like Factor) protect us against infectious and parasitic diseases?
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Statistical radii associated with amino acids to determine the contact map: fixing the structure of a type I cohesin domain in theClostridium thermocellumcellulosome
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Sequences of internal transcribed spacer 1, 5.8S ribosomal RNA gene and internal transcribed spacer 2 of psychrotolerant pigment-producing yeast-like fungi
Open Research DataDNA encoding ITS1-5.8S-ITS2 fragments of psychrotolerant pigment-producing yeast-like fungi named Red, Pink and Black were PCR amplified using ITS1 5' TCCGTAGGTGAACCTGCGG 3' and ITS4 5’ TCCTCCGCTTATTGATATGC 3’ primers and sequenced by Sanger method using the same primers.