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Search results for: david hume
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Hyponastic Leaves 1 Interacts with RNA Pol II to Ensure Proper Transcription of MicroRNA Genes
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Cyclic voltammetric biosensing of cellular ionic secretion based on silicon nanowires to detect the effect of paclitaxel on breast normal and cancer cells
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Photodynamic therapy – mechanisms, photosensitizers and combinations
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Associations between Diet and Changes in Pain Levels among Young Women with Premenstrual Syndrome—A Preliminary Study during the COVID-19 Pandemic
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The Role of Visceral Therapy in the Sexual Health of Women with Endometriosis during the COVID-19 Pandemic: A Literature Review
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Physiotherapy for Chronic Pelvic Pain in Endometriosis
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Antibiotic-Based Conjugates Containing Antimicrobial HLopt2 Peptide: Design, Synthesis, Antimicrobial and Cytotoxic Activities
PublicationRecent studies have shown that modified human lactoferrin 20−31 fragment, named HLopt2, possesses antibacterial and antifungal activity. Thus, we decided to synthesize and evaluate the biological activity of a series of conjugates based on this peptide and one of the antimicrobials with proven antibacterial (ciprofloxacin, CIP, and levofloxacin, LVX) or antifungal (fluconazole, FLC) activity. The drugs were covalently connected...
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Quantitative fluorescent determination of DNA – Ochratoxin a interactions supported by nitrogen-vacancy rich nanodiamonds
PublicationOchratoxin A (OTA) is a hazardous contaminant of a large variety of plant and animal originated food. Herein, we report an interaction of OTA with calf thymus DNA (ct DNA) on the nanodiamond surface. We employed multispectroscopic techniques to elucidate the binding mechanism of OTA with ct DNA. The fluorescence and UV–Vis spectroscopy results show that OTA binds to ds ct DNA and forms complexes. We obtained the binding constants...
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From Janus nanoparticles to multi-headed structure - photocatalytic H2 evolution
PublicationThe generation of stable, high-performance photocatalysts with appropriate charge distribution for solar energy conversion is currently one of the urgent missions of photocatalytic science. Recent studies have shown that the Janus NPs with characteristic varied, asymmetric structure may boost overall efficiency of photocatalys. However, there is still a lack of systematic studies in which Janus-type particles are used in the hydrogen...
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Successive cytotoxicity control by evolutionary surface decorated electronic push-pull green ZnCr-LDH nanostructures: Drug delivery enlargement for targeted breast cancer chemotherapy
PublicationThe reason for the increasing bioavailability and biocompatibility of the porous nanomaterials in the presence of different (bio)molecules is still unknown. The role of difference functional groups and their interactions with the potential bioavailability and biocompatibility is of great importance. To investigate the potential contribution of the electronic effects (especially on the surface of the porous nanomaterials) on their...
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Chromatographic and Spectroscopic Identification and Recognition of Natural Dyes, Uncommon Dyestuff Components, and Mordants: Case Study of a 16th Century Carpet with Chintamani Motifs
PublicationA multi-tool analytical practice was used for the characterisation of a 16th century carpet manufactured in Cairo. A mild extraction method with hydrofluoric acid has been evaluated in order to isolate intact flavonoids and their glycosides, anthraquinones, tannins, and indigoids from fibre samples. High-performance liquid chromatography coupled to spectroscopic and mass spectrometric detectors was used for the identification of...
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Comparison of different digestion methods for proteomic analysis of isolated cells and FFPE tissue samples
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Hydrophilic domain II of Escherichia coli Dr fimbriae facilitates cell invasion
PublicationStosując techniki mutagenezy ukierunkowanej oraz mikroskopii elektronowej stwierdzono, że hydrofilowa domena II białka podjednostkowego DraE fimbrii jest odpowiedzialna za inwazję komórki. Otrzymane wyniki są zgodne z interpretacją, że fenotypy fimbrii Dr wiązania i inwazji komórki HeLa mogą być oddzielone.
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Using LSTM networks to predict engine condition on large scale data processing framework
PublicationAs the Internet of Things technology is developing rapidly, companies have an ability to observe the health of engine components and constructed systems through collecting signals from sensors. According to output of IoT sensors, companies can build systems to predict the conditions of components. Practically the components are required to be maintained or replaced before the end of life in performing their assigned task. Predicting...
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Audio Content and Crowdsourcing: A Subjective Quality Evaluation of Radio Programs Streamed Online
PublicationRadio broadcasting has been present in our lives for over 100 years. The transmission of speech and music signals accompanies us from an early age. Broadcasts provide the latest information from home and abroad. They also shape musical tastes and allow many artists to share their creativity. Modern distribution involves transmission over a number of terrestrial systems. The most popular are analog FM (Frequency Modulation) and...
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Synthesis of Novel Arginine Building Blocks with Increased Lipophilicity Compatible with Solid-Phase Peptide Synthesis
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SERRATE interacts with the nuclear exosome targeting (NEXT) complex to degrade primary miRNA precursors in Arabidopsis
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A Maximum-Likelihood Approach to Force-Field Calibration
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Allergic inflammation in lungs and nasal epithelium of rat model is regulated by tissue-specific miRNA expression
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ZASTOSOWANIE W ELEKTROTECHNICE METOD ANALIZY I SYNTEZY UKŁADÓW DO POPRAWY JAKOŚCI ENERGII I STEROWANIA
PublicationW artykule przedstawiono podsumowanie wieloletnich prac badawczych prowadzonych w Instytucie Elektrotechniki i Informatyki przez zespoły naukowe pod kierunkiem Prof. Mariana Pasko. Badania te dotyczyły wybranych zagadnień z zakresu analizy i syntezy układów do poprawy wybranych wskaźników jakości energii elektrycznej oraz układów sterowania napędów elektrycznych. Przeprowadzono zarówno analizę...
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Crystalline Polysaccharides: A Review
PublicationThe biodegradability and mechanical properties of polysaccharides are dependent on their architecture (linear or branched) as well as their crystallinity (size of crystals and crystallinity percent). The amount of crystalline zones in the polysaccharide significantly governs their ultimate properties and applications (from packaging to biomedicine). Although synthesis, characterization, and properties of polysaccharides have been...
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Detection of the Plant Pathogen Pseudomonas Syringae pv. Lachrymans on Antibody-Modified Gold Electrodes by Electrochemical Impedance Spectroscopy
PublicationThe present work describes an impedimetric immunosensor for Pseudomonas syringae pv. lachrymans (Psl) detection. This pathogen infects many crop species causing considerable yield losses, thus fast and cheap detection method is in high demand. In the assay, the gold disc electrode was modified with 4-aminothiophenol (4-ATP), glutaraldehyde (GA), and anti-Psl antibodies, and free-sites were blocked with bovine serum albumin (BSA)....
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Green products from herbal medicine wastes by subcritical water treatment
PublicationHerbal medicine wastes (HMWs) are byproducts of medicine factories, which are mainly landfilled for their environmental problems. Only bearing in mind the contamination and concerns caused by the COVID-19 pandemic and environmental emissions, the worth of herbal medicine wastes management and conversion to green products can be understood. In this work, subcritical water treatment was carried out batch-wise in a stainless tube...
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Authors’ Response to the Letter by Lamarca et al. Entitled “Temozolomide-Capecitabine Chemotherapy for Neuroendocrine Neoplasms: The Dilemma of Treatment Duration” Regarding “Activity and Safety of Standard and Prolonged Capecitabine/Temozolomide Administration in Patients with Advanced Neuroendocrine Neoplasms”
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Ionosphere variability I: Advances in observational, monitoring and detection capabilities
PublicationThe paper aims to review recent advances regarding the observational and monitoring capabilities of the ionization conditions in the Earth's upper atmosphere. The analysis spans both ground and space-based experiments, seeking for new installations and/or missions, new or upgraded instrumentation and/or observational network establishments as means for advancing current understanding and prediction ability of the ionosphere variability....
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Tumor infiltrating lymphocyte signature is associated with single nucleotide polymorphisms and predicts survival in esophageal squamous cell carcinoma patients
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Molecular Characterization of Growth Hormone-producing Tumors in the GC Rat Model of Acromegaly
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CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures
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A concerted evolution of supramolecular interactions in a {cation; metal complex; π-acid; solvent} anion-π system
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The cytoprotective role of antioxidants in mammalian cells under rapidly varying temperature, pressure and UV conditions during stratospheric balloon campaign
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The Application of Physiotherapy in Urinary Incontinence
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Heat transfer investigations in a liquid that is mixed by means of a multi-ribbon mixer
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Dynamics of Antimicrobial Peptide Encapsulation in Carbon Nanotubes: The Role of Hydroxylation
PublicationIntroduction: Carbon nanotubes (CNTs) have been widely employed as biomolecule carriers, but there is a need for further functionalization to broaden their therapeutic application in aqueous environments. A few reports have unraveled biomolecule–CNT interactions as a measure of response of the nanocarrier to drug-encapsulation dynamics. Methods: Herein, the dynamics of encapsulation of the antimicrobial peptide HA-FD-13 (accession...
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2D MXene nanocomposites: electrochemical and biomedical applications
PublicationIn recent years, key questions about the interaction of 2D MXene nanomaterials in electrochemical and biomedical applications have been raised. Most research has focused on clarifying the exclusive properties of the materials; however, only limited reports have described the biomedical applications of 2D nanomaterials. 2D MXenes are monolayer atomic nanosheets resulting from MAX phase ceramics. The hydrophilic properties, metallic...
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Structural properties of mixed conductor Ba1−xGd1−yLax+yCo2O6−δ
PublicationBa1−xGd1−yLax+yCo2O6−δ (BGLC) compositions with large compositional ranges of Ba, Gd, and La have been characterised with respect to phase compositions, structure, and thermal and chemical expansion. The results show a system with large compositional flexibility, enabling tuning of functional properties and thermal and chemical expansion. We show anisotropic chemical expansion and detailed refinements of emerging phases as La is...
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A new approach to β-decays studies impacting nuclear physics and astrophysics: The PANDORA setup
PublicationTheory predicts that lifetimes of β-radionuclides can change dramatically as a function of their ionization state. Experiments performed in Storage Rings on highly ionized atom have proven nuclei can change their beta decay lifetime up to several orders of magnitude. The PANDORA (Plasmas for Astrophysics, Nuclear Decay Observation and Radiation for Archaeometry) experiment is now conceived to measure, for the first time, nuclear...
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High pressure and time resolved studies of optical properties of n-type doped GaN/AlN multi-quantum wells: Experimental and theoretical analysis
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Investigation of Serine‐Proteinase‐Catalyzed Peptide Splicing in Analogues of Sunflower Trypsin Inhibitor 1 (SFTI‐1)
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The influence of electromagnetic pollution on living organisms – historical trends and forecasting changes
PublicationCurrent technologies have become a source of omnipresent electromagnetic pollution from generated electromagnetic fields and resulting electromagnetic radiation. In many cases this pollution is much stronger than any natural sources of electromagnetic fields or radiation. Wireless and radio communication, electric power transmission or devices in daily use such as smartphones, tablets and portable computers every day expose people...
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Biofilm Growth Causes Damage to Silicone Voice Prostheses in Patients after Surgical Treatment of Locally Advanced Laryngeal Cancer
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Ab initio and experimental studies of polarization and polarization related fields in nitrides and nitride structures
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BEXUS 30 Stardust – Preliminary Results of Investigation of Microbes in the Stratosphere
PublicationThe stratospheric microbiome has been investigated several times using the methods of classical microbiology. In this experiment, we have combined them with some novel approaches.. Diversification of methods has helped better describe the collected microorganisms. The results of the experiment may help better understand the mechanisms of survivability of microorganisms in stratospheric conditions.
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Gynaecology, physiotherapy and balneoclimatology - an interdisciplinary approach
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Green Polymer Nanocomposites for Skin Tissue Engineering
PublicationFabrication of an appropriate skin scaffold needs to meet several standards related to the mechanical and biological properties. Fully natural/green scaffolds with acceptable biodegradability, biocompatibility, and physiological properties quite often suffer from poor mechanical properties. Therefore, for appropriate skin tissue engineering and to mimic the real functions, we need to use synthetic polymers and/or additives as complements...
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Comparative study on the effectiveness of various types of road traffic intensity detectors
PublicationVehicle detection and speed measurements are crucial tasks in traffic monitoring systems. In this work, we focus on several types of electronic sensors, operating on different physical principles in order to compare their effectiveness in real traffic conditions. Commercial solutions are based on road tubes, microwave sensors, LiDARs, and video cameras. Distributed traffic monitoring systems require a high number of monitoring...
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Theoretical Encapsulation of Fluorouracil (5-FU) Anti-Cancer Chemotherapy Drug into Carbon Nanotubes (CNT) and Boron Nitride Nanotubes (BNNT)
PublicationIntroduction: Chemotherapy with anti-cancer drugs is considered the most common approach for killing cancer cells in the human body. However, some barriers such as toxicity and side effects would limit its usage. In this regard, nano-based drug delivery systems have emerged as cost-effective and efficient for sustained and targeted drug delivery. Nanotubes such as carbon nanotubes (CNT) and boron nitride nanotubes (BNNT) are promising...
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A review on computer‐aided chemogenomics and drug repositioning for rational COVID ‐19 drug discovery
PublicationApplication of materials capable of energy harvesting to increase the efficiency and environmental adaptability is sometimes reflected in the ability of discovery of some traces in an environment―either experimentally or computationally―to enlarge practical application window. The emergence of computational methods, particularly computer-aided drug discovery (CADD), provides ample opportunities for the rapid discovery and development...
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High pressure studies of Eu2+ and Mn2+ doped NaScSi2O6 clinopyroxenes
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Oxide catalysts for carbon nanotube and few layer graphene formation
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Trends in biomedical analysis of red blood cells – Raman spectroscopy against other spectroscopic, microscopic and classical techniques
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