displaying 1000 best results Help
Search results for: CHIRAL PHARMACEUTICALS
-
Selected issues related to the toxicity of ionic liquids and deep eutectic solvents—a review
PublicationGreen Chemistry plays a more and more important role in implementing rules of sustainable development to prevent environmental pollution caused by technological processes, while simultaneously increasing the production yield. Ionic liquids (ILs) and deep eutectic solvents (DESs) constitute a very broad group of substances. Apart from many imperfections, ILs and DESs have been the most promising discoveries in the world of Green...
-
Chitra Tc
People -
The effect of morphology and crystalline structure of Mo/MoO3 layers on photocatalytic degradation of water organic pollutants
PublicationMolybdenum oxide layers were formed by anodization of the Mo metallic foil in a water/ethylene glycol-based electrolyte containing fluoride ions. The as-prepared, amorphous samples were annealed in air at different temperatures in a range from 100 �C to 700 �C. The crystal phase and morphology of anodized and annealed MoO3 layers were investigated using X-ray diffraction, Raman spectroscopy, and scanning electron microscopy. The...
-
Nanoparticles: Synthesis, characteristics, and applications in analytical and other sciences
PublicationNanoparticles (NPs) are widely employed in different research areas, ranging from analytical chemistry and environmental science to medicine, the agriculture and pharmaceutical industry. This is mainly due to the unique characteristics of NPs and the novelty they introduce in such applications. In analytical chemistry, the role of NPs can differ depending on the nature of the steps involved in analytical process. NPs are probably...
-
Environmentally Oriented Models and Methods for the Evaluation of Drug x Drug Interaction Effects
PublicationThis detailed review compares known and widely used methods for drug interaction estimation, some of which now have historical significance. Pharmaceutical application has been noted as far back as several thousand years ago. Relatively late in the 20th century, however, researchers became aware that their fate and metabolism, which still remain a great challenge for environmental analysts and risk assessors. For the patient’s...
-
Model yeast as a versatile tool to examine the antioxidant and anti-ageing potential of flavonoids, extracted from medicinal plants
Publication -
Natural Quercetin Analogues Modulate Oxidative Stress Tolerance and Increase Lifespan Extension of S. cerevisiae ( proceeding)
Publication -
Yeast as a Model to Characterize Anti-Aging Potential of Flavonoids (poster)
Publication -
Yeast as a Model to Characterize Anti-Aging Potential of Flavonoids (poster)
Publication -
Yeast as a Model to Characterize Anti-Aging Potential of Flavonoids (poster)
Publication -
Yeast as a model to analyse the oxidative stress against acetic acid and anti-aging potential of Rice Flavonoids proceeding
Publication -
An SDN-based technique for reducing handoff times in WiFi networks
Publication -
Modeling of Wireless Traffic Load in Next Generation Wireless Networks
Publication -
Analysis of Impulse Responses Measured in Motion in a Towing Tank
PublicationThe growing interest in developing autonomous underwater vehicles (AUVs) and creating underwater sensor networks (USNs) has led to a need for communication tools in underwater environments. For obvious reasons, wireless means of communication are the most desirable. However, conducting research in real conditions is troublesome and costly. Moreover, as hydroacoustic propagation conditions change very significantly, even during...
-
Analysis of Impulse Responses Measured in Motion in a Towing Tank
PublicationThe growing interest in developing autonomous underwater vehicles (AUVs) and creating underwater sensor networks (USNs) has led to a need for communication tools in underwater environments. For obvious reasons, wireless means of communication are the most desirable. However, conducting research in real conditions is troublesome and costly. Moreover, as hydroacoustic propagation conditions change very significantly, even during...
-
Comparison of Doppler Effect Estimation Methods for MFSK Transmission in Multipath Hydroacoustic Channel
PublicationUnderwater wireless communication remains a challenging topic, particularly for applications such as wreck penetration where multipath and Doppler effects are very intense. These effects are becoming even more difficult to mitigate for fast data transmission systems that utilize wideband signals. Due to the low propagation speed of acoustic wave in the water, there is a significant difference between the Doppler shift for lower...
-
Double layer adhesive silicone dressing as a potential dermal drug delivery film in scar treatment
Publication -
In vitro and in vivo evaluation of sandwich-like mesoporous silica nanoflakes as promising anticancer drug delivery system
Publication -
Could spray-dried microbeads with chitosan glutamate be considered as promising vaginal microbicide carriers? The effect of process variables on the in vitro functional and physicochemical characteristics
Publication -
Brain/blood distribution described by a combination of partition coefficient and molecular mass
Publication -
Roxithromycin-loaded lipid nanoparticles for follicular targeting
Publication -
Significance of polymethylmethacrylate (PMMA) modification by zinc oxide nanoparticles for fungal biofilm formation
Publication -
Transdermal transport of collagen and hyaluronic acid using water in oil microemulsion
PublicationCollagen and hyaluronic acid (HA) are biopolymers that affect the appearance and condition of the skin. Delivery of these compounds into the skin is highly challenging since have a number of disadvantageous properties, such as high molecular weight and hydrophilicity. Here, we evaluated the transdermal penetration of low and high molecular weight collagen and HA from microemulsions. A number of microemulsion formulations, differing...
-
Optimization of using recuperative braking energy on a double-track railway line
PublicationIn the introduction, possible ways of reusing energy from recuperation are presented. Next, the paper investigates the possibility of using regenerative braking in the range allowed by the detailed timetable by adopting the method of transferring the recovered electric energy directly to the catenary and immediate use of this energy by another train at the same power section. In the main part of the work, it is shown, that the...
-
Modelowanie reorganizacji ruchu w transporcie szynowym zwiększające efektywne wykorzystanie energii z hamowania odzyskowego
PublicationWe wstępie artykułu przedstawiono metody wykorzystania energii elektrycznej odzyskanej w procesie hamowania elektrodynamicznego. Szczególną uwagę zwrócono na metodę zwrotu odzyskanej energii do sieci jezdnej i wykorzystania jej przez inne pojazdy szynowe, której efektywne zastosowanie niejednokrotnie wymaga reorganizacji ruchu. W pracy przeanalizowano opisany w literaturze model organizacji ruchu w transporcie szynowym, który uwzględnia...
-
Optimization of Train Energy Cooperation Using Scheduled Service Time Reserve
PublicationThe main aim of the paper was to develop an innovative approach to the preliminary estimation possibility of train energy cooperation based on data from timetables, without traction calculations. The article points out the need to strive for sustainable and environmentally friendly transport. It was pointed out that rail transport using electric traction is one of the more ecological branches of transport. It also offers a number...
-
Optimization of the efficiency of braking energy recovery in rail transport by changing arrival time
PublicationThe article refers to the previous work of the authors, in which the model of traffic organization of cooperating trains including the optimization of the use of energy returned to the catenary was presented. In the presented article, the model was modified by changing the main control variable, which affects the efficient use of energy. Departure time was changed for the arrival time of the train to the stop or station. The optimization...
-
Optymalizacja efektywności hamowania odzyskowego w transporcie szynowym przez sterowanie czasem przyjazdu na stację
PublicationArtykuł nawiązuje do poprzednich prac autorów, w których przedstawiono model organizacji ruchu kooperujących pociągów z uwzględnieniem optymalizacji wykorzystania energii zwracanej do sieci jezdnej. W przedstawionej pracy zmodyfikowano model zmieniając główną zmienną sterującą, mającą wpływ na efektywne wykorzystanie energii, z czasu odjazdu na czas przyjazdu pociągu na stację lub przystanek. Optymalizacja dokonywana jest przez...
-
Marek Szelągowski dr
PeopleMarek Szelągowski has participated in the creation and implementation of IT solutions in the fields of accounting, human resources management, production, IT infrastructure management, etc. As the CIO of the BUDIMEX Group in 2000–2008 he was responsible for the accommodation of informatization strategies to the changing needs of the business sector. He was managing and participating in analyses and optimizations of business processes...
-
Diqiu Kexue - Zhongguo Dizhi Daxue Xuebao/Earth Science - Journal of China University of Geosciences
Journals -
The power of silence? opinion contagion and the surprise of the polish 2005 parlamentary and presidential elections
PublicationThis paper investigates opinion contagion in collective behaviour using threshold model (Granovetter (1978), Krassa(1988)). The theoretical background is the spiral of silence concept developed by Noelle-Neumann (1974), arguing that people only assert their opinions if they perceive a minimal support from a relevant proportion of others. We apply the model to explain the dispersion between pre-elections preferences and the final...
-
Fundamentals of Electrotechnics and Electronics II - project China [2023/24]
e-Learning CoursesIntroduction and analysis of fundamental electronic components, circuits and applications.
-
Interferon‐free therapy as the cause of white matter tracts and cerebral perfusion recovery in patients with chronic hepatitis C
Publication -
Inverse shadowing and related measures
PublicationWe study various weaker forms of the inverse shadowing property for discrete dynamical systems on a smooth compact manifold. First, we introduce the so-called ergodic inverse shadowing property (Birkhoff averages of continuous functions along an exact trajectory and the approximating one are close). We demonstrate that this property implies the continuity of the set of invariant measures in the Hausdorff metric. We show that the...
-
Biomolecular influenza virus detection based on the electrochemical impedance spectroscopy using the nanocrystalline boron-doped diamond electrodes with covalently bound antibodies
PublicationNew rapid pathogen detection methods with improved cost-effectiveness and efficiency are currently in the focus of the scientists from all over the world. Based on the experiences from the rapid spread of the influenza virus pandemic in 2009 it is clear that the development of the system for early diagnosis of this infection is essential. The crucial stage of the treatment is the detection of the viral infection during its initial...
-
Essays on China's international trade - focus on One-Belt One-Road initiative
PublicationThis thesis explores China's international trade from trade, global value chains (GVCs) and export diversity, focusing on the "One-Belt One-Road" (OBOR) initiative proposed at the end of 2013. Specifically, I verify the potential association of OBOR with bilateral imports and exports in the first chapter. Then the relationship between OBOR and GVCs has been explored in Chapter 2. And I have extended the research in GVCs to China's...
-
Identification of synergistic and antagonistic actions of environmental pollutants: Bisphenols A, S and F in the presence of DEP, DBP, BADGE and BADGE·2HCl in three component mixtures
PublicationEcosystems are facing increased pressure due to the emission of many classes of emerging contaminants. However, very little is known about the interactions of these pollutants, such as bisphenols (BPs), plasticizers or pharmaceuticals. By employing bioluminescent bacteria (Microtox assay), we were able to define interactions between selected emerging pollutants (namely BPA, BPS, BPF, BADGE, BADGE·2HCl, DEP, DBP) in ternary mixtures, at...
-
Impact of selected drugs and their binary mixtures on the germination of Sorghum bicolor (sorgo) seeds
PublicationThe aim of this study was to assess the toxicological potential of binary drug mixtures and individual drugs under different pH conditions with different inorganic ion additions on the germination of Sorghum bicolor (sorgo) seeds. To assess whether the given drug mixtures were more phytotoxic than the individual compounds, concentration addition (CA) and independent action (IA) approaches were applied to estimate the predicted...
-
On Tradeoffs Between Width- and Fill-like Graph Parameters
PublicationIn this work we consider two two-criteria optimization problems: given an input graph, the goal is to find its interval (or chordal) supergraph that minimizes the number of edges and its clique number simultaneously. For the interval supergraph, the problem can be restated as simultaneous minimization of the path width pw(G) and the profile p(G) of the input graph G. We prove that for an arbitrary graph G and an integer t ∈ {1,...
-
Demodulacja AM-FM dyskretnych sygnałów świergotowych
PublicationW pracy zaprezentowano dwa nowe krótkie (4-punktowe) estymatory amplitudy chwilowej rzeczywistych sygnałów świergotowych (ang. chirp) współpracujące z 4-punktowym estymatorem pulsacji chwilowej MODCOV4p. W ten sposób otrzymano dwa demodulatory AM-FM o stosunkowo dużej dokładności obu estymat i o zakresie dynamicznym AM i FM wystarczająco szerokim do większości praktycznych zastosowań.
-
Cloning, expression, purification and characterization of recombinant trehalose synthase from Deinococcus radiodurans.
PublicationTrehalose (α-D-glucopyranosyl-1,1-α-D-glucopyranoside) is a nonreducing disacharide in which the two glucose molecules are linked trough a α-1,1-glycosidic bond. Trehalose is readily hydrolyzed to glucose and can be used as a reserve of that sugar in the cell. The presence of trehalose was found in the cells of fungi and yeasts, bacteria, nematodes, insects, eggs, pupae and some plants. The characteristics of trehalose make it...
-
Formulation, characterisation and in vitro studies of doxorubicin-loaded silica–polydimethylsiloxane granules
Publication -
Propensity of salicylamide and ethenzamide cocrystallization with aromatic carboxylic acids
PublicationThe cocrystallization of salicylamide (2-hydroxybenzamide, SMD) and ethenzamide (2-ethoxybenzamide, EMD) with aromatic carboxylic acids was examined both experimentally and theoretically. The supramolecular synthesis taking advantage of the droplet evaporative crystallization (DEC) technique was combined with powder diffraction and vibrational spectroscopy as the analytical tools. This led to identification of eleven new cocrystals...
-
Induced circularly polarized luminescence for revealing DNA binding with fluorescent dyes
Publication -
Development of biodegradable polyesters with various microstructures for highly controlled release of epirubicin and cyclophosphamide
Publication -
The comparative study of micellar TLC and RP-TLC as potential tools for lipophilicity assessment based on QSRR approach
Publication -
Method development and validation for optimized separation of quercetin derivatives in selected Potentilla species using high-performance thin-layer chromatography photodensitometry method
Publication -
Application of reversed-phase thin layer chromatography and QSRR modelling for prediction of protein binding of selected β-blockers
Publication -
Drug affinity to human serum albumin prediction by retention of cetyltrimethylammonium bromide pseudostationary phase in micellar electrokinetic chromatography and chemically advanced template search descriptors
Publication -
Ocular irritation and cyclosporine A distribution in the eye tissues after administration of Solid Lipid Microparticles in the rabbit model
Publication