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Search results for: MUCHOMOR CYTRYNOWY (AMANITA CITRINA)
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Chemosensitization of multidrug resistant Candida albicans by the oxathiolone fused chalcone derivatives
PublicationThree structurally related oxathiolone fused chalcone derivatives appeared effective chemosensitizers, able to restore in part sensitivity to fluconazole of multidrug-resistant C.albicans strains. Compound 21 effectively chemosensitized cells resistant due to the overexpression of the MDR1 gene, compound 6 reduced resistance of cells overexpressing the ABC-type drug transporters CDR1/CDR2 and derivative 18 partially reversed fluconazole...
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Dietary intervention with red beet juice ameliorates side effects resulting from oxidative stress during cancer chemotherapy with doxorubicin
PublicationChemoterapia nowotworów wiąże się ze stymulacją stresu oksydacyjnego, wywołującego niekorzystne efekty uboczne w organizmie. Panuje pogląd, że wprowadzenie do terapii przeciwutleniaczy może te niekorzystne efekty uboczne zmniejszyć. W naszych badaniach jako źródło utleniaczy wykorzystaliśmy sok z buraka ćwikłowego. Pokazaliśmy, że jego zastosowanie w kombinacji z lekiem przeciwnowotworowym doksorubicyną znacznie poprawia efekty...
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Influence of S-Oxidation on Cytotoxic Activity of Oxathiole-Fused Chalcones
PublicationSynthesis, in vitro cytotoxic activity, and interaction with tubulin of oxidized, isomeric 1-(5-alkoxybenzo[d] [1,3]oxathiol-6-yl)-3-phenylprop-2-en-1-ones and 1-(6- alkoxybenzo[d][1,3]oxathiol-5-yl)-3-phenylprop-2-en-1- ones are described. Most of the compounds demonstrated cytotoxic activity at submicromolar concentrations. It was found that oxidation of sulfur atom of the oxathiole-fused chalcones strongly influenced activity...
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Hydroperoxyl radical and formic acid formation from common DNA stabilizers upon low energy electron attachment
Publication2-Amino-2-(hydroxymethyl)-1,3-propanediol (TRIS) and ethylenediaminetetraacetic acid (EDTA) are key components of biological buffers and are frequently used as DNA stabilizers in irradiation studies. Such surface or liquid phase studies are done with the aim to understand the fundamental mechanisms of DNA radiation damage and to improve cancer radiotherapy. When ionizing radiation is used, abundant secondary electrons are formed...
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów.
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów.
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów.
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Szkolenie w ramach POWER 3.4
EventsSztuka autoprezentacji dla dydaktyków i prelegentów
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Zespół Katedry Historii, Teorii Architektury i Konserwacji Zabytków
Research TeamsTematyka badawcza Katedry oscyluje wokół badań architektonicznych architektury średniowiecznej i nowożytnej regionu Morza Bałtyckiego. Do głównych zainteresowań zespołu katedralnego możemy zaliczyć problematykę badawczą i konserwatorską zabytków architektury XIX i XX wieku, jak również badawcze skoncentrowane na problematyce architektury sakralnej, zwłaszcza cysterskiej. Teoria konserwacji oraz historii fortyfikacji to kolejna...
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Towards the Application of Structure-Property Relationship Modeling in Materials Science: Predicting the Seebeck Coefficient for Ionic Liquid/Redox Couple Systems
PublicationThis work focuses on determining the influence of both ionic liquid (IL) type and redox couple concentration on Seebeck coefficient values of such a system. The quantitative structure property relationship (QSPR) and read-across techniques are proposed as methods to identify structural features of ILs (mixed with LiI/I2 redox couple), which have the most influence on the Seebeck coefficient (Se) values of the system. ILs consisting...
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KAforHR Innovative Entrepreneurs and Innovation Support for SMEs: Knowledge Alliance „Human Resources and Organizational Development“
ProjectsProject realized in Department of Management according to 600923-EPP-1-2018-1-DE-EPPKA2-KA agreement from 2018-11-28
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Teratomas of Drosera capensis var. alba as a source of naphthoquinone: ramentaceone
PublicationPlants belonging to genus Drosera (family Droseraceae) contain pharmacologically active naphthoquinones such as ramentaceone and plumbagin. Hairy root cultures obtained following Agrobacterium rhizogenes-mediated transformation have been reported to produce elevated levels of secondary compounds as well as exhibit desirable rapid biomass accumulation in comparison to untransformed plants. The aim of this study was to establish...
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Direct QSPR: the most efficient way of predicting organic carbon/water partition coefficient (log K OC) for polyhalogenated POPs
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Novel Cell Permeable Polymers of N-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublicationA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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Integrated model for the fast assessment of flood volume: Modelling – management, uncertainty and sensitivity analysis
PublicationThe specific flood volume is an important criterion for assessing the performance of sewage networks. It has been shown that its value is greatly influenced by the layout of the sewers in the catchment area, which is usually expressed by a fractal dimension. Currently, only mechanistic models (such as SWMM) enable the determination of the impact of the layout of the sewers on flooding volume, but they require additional and robust...
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The role of electrolysis and enzymatic hydrolysis treatment in the enhancement of the electrochemical properties of 3D-printed carbon black/poly(lactic acid) structures
PublicationAdditive manufacturing, also known as 3D printing, is beginning to play an unprecedented role in developing many applications for industrial or personalized products. The conductive composite structures require additional treatment to achieve an electroactive surface useful for electrochemical devices. In this paper, the surfaces of carbon black/poly(lactic acid) CB-PLA printouts were activated by electrolysis or enzymatic digestion...
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Conversion of waste biomass to designed and tailored activated chars with valuable properties for adsorption and electrochemical applications
PublicationWaste biomass, a renewable energy source, is inexpensive material that has great potential in sorp-tion and electrochemical application. The selected waste materials (corncobs, coconut shells, wal-nuts, and pistachio husks) allow to close the production cycle and enable material recycling, which are important aspects in the hierarchy of waste management. The proposed methodology for pro-duction and activation of biochars can be...
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Biological and mechanical properties of bone cement with nanoparticles - in vivo and in vitro research
PublicationDespite antibiotics preventive treatment, before and after an implant implementation, risk of infection are real. These infections at the implant surface develop in a few months after applying them into the body. To prevent the development of bacteria and to reduce the risk of infection, implants coated with nanoparticles come into use. The Mechanical Department of the Technical University of Gdańsk carried out a research with...
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Biological and mechanical properties of bone cement with nanoarticles - in vitro and in vivo research
PublicationDespite antibiotic preventive treatment both before and after implant implementation, the risks of infection are real. These infections develop at the implant surface a few months after inserting them into the body. To prevent the development of bacteria and reduce the risk of infection, implants coated with nanoparticles are used. The Mechanical Department of the Technical University of Gdansk carries out research into using bone...
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WETI - Inf. z. - Analiza matematyczna 19/20 (A. Dąbrowicz-Tlałka)
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Przykładowe testy z Matematyki Elementarnej
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Szablon e-kursu do przedmiotu - na rok ak. 2021/2022
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WEiA - TWiE s.2: ćw. gr.2- 2023/24 (M.Łapińska) Matematyka
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WEiA - TWiE s.1: ćw. gr.1 - 2023/24 (A.Tlałka) Matematyka
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eMateriały do laboratorium: symulacje na automatach komórkowych w Matlabie - teoria i praktyka
e-Learning CoursesKurs stanowi uzupełnienie prowadzonego przeze mnie laboratorium. We wszystkich opracowanych przeze mnie materiałach zakładam, że Student nie miał wcześniej styczności ze środowiskami MATLAB ani OCTAVE.Dzięki przerobieniu kursu każdy sumienny Student:- nabierze biegłości w posługiwaniu się środowiskiem służącym do obliczeń symbolicznych,- będzie potrafił rozwiązywać pewne składowe zadań matematycznych w MATLABie,- pozna metody tworzenia...
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WEiA - TwiE gr.2 i 3 - Liczby zespolone 2023/24 (M.Łapińska)
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WEiA - TWiE s.1: 2023/24 (A.Tlałka) Propedeutyka Matematyki i Matematyka I
e-Learning CourseseKurs do przedmiotów Propedeutyka Matematyki i Matematyka 1 sem.1 dla kierunku TWiE WEiA. Rok akademicki 2023/2024 (Okładka kursu - https://pixabay.com/pl/photos/matematyka-komputer-laptop-biznes-3821034/)
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WCh - Bt s.1: ćw. gr.4,5, 2023/24 (E.Kozłowska-Walania) - Matematyka
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WEiA - TWiE s.1: ćw. gr.2,3 - 2023/24 (M.Łapińska) Matematyka
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WEiA - TWiE – s2: 2023/24 (A.Tlałka)
e-Learning CoursesMatematyka 2 TWiE WEiA
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WCh - Bt 4 - Mat. ćw. s2: 23/24 (K.Kozłowska-Walania)
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Ankieta 2023/2024
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Thermodynamic study of new antiepileptic compounds by combining chromatography on the phosphatidylcholine biomimetic stationary phase and differential scanning calorimetry
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Capecitabine and temozolomide combination for treatment of high-grade, well-differentiated neuroendocrine tumour and poorly-differentiated neuroendocrine carcinoma — retrospective analysis
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Synthesis of oxathiolone fused chalkones bearing O-aminoalkyl side chain. Comparison of stability of isomeric benzoxathiolones under alkylation reaction conditions
PublicationIzomeryczne oksatiolonowe sprzężone chalkony zawierające O-alkilowe łańcuchy boczne otrzymano w wyniku kondensacji odpowiednich benzoksatiolonów z podstawionymi benzaldehydami. Wyjściowe benzoksatiolony otrzymano w wyniku alkilowania odpowiednich fenoli chlorkami aninoalkilowymi, jednakże reakcja była często komplikowana w wyniku otwarcia pierścienia oksatiolonowego poprzez grupę aminową. Określono aktywność cytotoksyczną i przeciwdrobnoustrojową...
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Copper(II) Complexes with 1-(Isoquinolin-3-yl)heteroalkyl-2-ones: Synthesis, Structure and Evaluation of Anticancer, Antimicrobial and Antioxidant Potential
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Tin Oxide Encapsulated into Pyrolyzed Chitosan as a Negative Electrode for Lithium Ion Batteries
PublicationTin oxide is one of the most promising electrode materials as a negative electrode for lithium-ion batteries due to its higher theoretical specific capacity than graphite. However, it suffers lack of stability due to volume changes and low electrical conductivity while cycling. To overcome these issues, a new composite consisting of SnO2 and carbonaceous matrix was fabricated. Naturally abundant and renewable chitosan was chosen...
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Independent Mechanisms Lead to Genomic Instability in Hodgkin Lymphoma: Microsatellite or Chromosomal Instability
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Erratum: Cuceu, C., et al. Independent Mechanisms Lead to Genomic Instability in Hodgkin Lymphoma: Microsatellite or Chromosomal Instability. Cancers 2018, 10, 233
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Determination of amino acids in urine of patients with prostate cancer and benign prostate growth
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Recycling of Industrial Waste as Soil Binding Additives—Effects on Soil Mechanical and Hydraulic Properties during Its Stabilisation before Road Construction
PublicationTo improve the in situ soil stabilization, different chemical additives are used (ion exchange compounds, additives based on H2SO4 or vinyl polymers, and organic additives using lignosul- fonates). One interesting alternative is the production of additives from various waste materials. The extensive testing of waste-based blends with soil was performed; the mechanical (unconfined compressive strength (UCS)) and hydraulic (capillary...
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The Brain of the city
PublicationIn order to highlight the characteristics of the West End of Wrocław, we conducted a site analysis. Using the strengths of the site, we were able to create a unique concept of the district while minimizing the impacts of weaknesses by design. The purpose of redesigning the West End of Wrocław is to attract new people to the district through the transformation of an identity. Initially, we conducted a SWOT analysis to identify the...
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WM (MiBM, Mechatronika, ZiIP, IMM) - Matematyka (S.Domachowski)
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WCh - GT - Mathematics 1 2021/22 (H.Guze) - Nowy
e-Learning Courses