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Search results for: MODELE IN VITRO
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Synthesis and in vitro characterization of freeze-dried doxorubicin-loaded silica/PEG composite
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Cinnamon powder: an in vitro and in vivo evaluation of antifungal and plant growth promoting activity
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Polyphenol-Enriched Composite Bone Regeneration Materials: A Systematic Review of In Vitro Studies
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Anticancer properties of low molecular weight oat beta-glucan – An in vitro study
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Edible Flowers Extracts as a Source of Bioactive Compounds with Antioxidant Properties—In Vitro Studies
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Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids
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In vivo and in vitro study of a novel nanohydroxyapatite sonocoated scaffolds for enhanced bone regeneration
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The effect of electromagnetic field on reactive oxygen species production in human neutrophilsin vitro
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In vitro enzyme inhibitory properties, antioxidant activities, and phytochemical profile of Potentilla thuringiaca
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In vitro anticariogenic effects of aerial parts of Drymocallis rupestris and its phytochemical profile
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In vitro anticariogenic effects of aerial parts of Potentilla recta and its phytochemical profile
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Butyrylcholinesterase signal sequence self-aggregates and enhances amyloid fibril formation in vitro
PublicationAlzheimer’s disease (AD) pathogenesis has been attributed to extracellular aggregates of amyloid β (Aβ) plaques and neurofibrillary tangles in the human brain. It has been reported that butyrylcholinesterase (BChE) also accumulates in the brain Aβ plaques in AD. We have previously found that the BChE substitution in 5′UTR caused an in-frame N-terminal extension of 41 amino acids of the BChE signal peptide. The resultant variant...
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Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion
PublicationPURPOSE: In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing provokes questions concerning potential epigenetic alterations occurring in expanded cells in the context of usefulness for transplantation and safety. The purpose of this study was to investigate as to whether keratinocyte expansion is associated with changes in the activity...
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Toward a unified model of mobile Business Intelligence (m-BI) acceptance and use
PublicationFactors affecting mobile business intelligence (m-BI) acceptance and use have become an increasingly important topic in practice due to the growing complexity of organizations, and their underlying information systems (IS). Since, one can notice considerable interest in m-BI, however, to the best of our knowledge few studies (if any) aim to synthesize the existing body of knowledge with regards to the factors affecting m-BI acceptance...
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Toward a unified model of mobile Business Intelligence (m-BI) acceptance and use
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Collective modes of the extended Hubbard model with negativeUand arbitrary electron density
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Identification of the Vistula Mounting tower model using measured modal data
PublicationW pracy przedstawiono problem identyfikacji pięcioparametrowego modelu zabytkowej wieży twierdzy Wisłoujście. Poszukiwane parametry wyznaczono jako rozwiązanie problemu minimalizacji błędu średniokwadratowego pomierzonych dwóch pierwszych częstości i pierwszej postaci drgań własnych. Do tego celu wykorzystano hierarchiczną procedurę minimalizacji przy zastosowaniu analizy wrażliwości. Analiza numeryczna potwierdziła efektywność...
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High speed milling vibration surveillance using modal model of the tool
PublicationPraca poświęcona jest nadzorowaniu drgań wirujących narzędzi w nowoczesnych frezarkach. Przedmiotem rozważań jest proces frezowania szybkościowego smukłym frezem kulistym na 5-osiowym centrum obróbkowym Deckel Maho DMU 50eVolution. Frezowanie smukłymi narzędziami jest często stosowane w przypadku nowoczesnych centrów obróbkowych. Uzasadnienie technologiczne wynika z konieczności dokładnego wykonywania złożonych kształtów geometrycznych...
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A new anisotropic bending model for nonlinear shells: Comparison with existing models and isogeometric finite element implementation
PublicationA new nonlinear hyperelastic bending model for shells formulated directly in surface form is presented, and compared to four existing prominent bending models. Through an essential set of elementary nonlinear bending test cases, the membrane and bending stresses of each model are examined analytically. Only the proposed bending model passes all the test cases, while the other bending models either fail or only pass the test cases for...
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Model identification in urban structures revitalisation = Metody identyfikacji modeli stosowane w rewitalizacji budowli miejskich
PublicationW pracy zaprezentowano wybrane metody diagnostyki dynamicznej stosowane w identyfikacji modeli budowli zabytkowych. Do tego celu wykorzystano pomiary częstości i postaci drgań własnych budowli poddanych oddziaływaniom środowiskowych. Wykazano efektywność stosowanych metod identyfikacji parametrycznej modeli oraz identyfikacji uszkodzeń na przykładzie trzech budowli: dzwonnicy Archikatedry w Wilnie, wieży Twierdzy Wisłoujście w...
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Model neuronowy jako alternatywa dla numerycznego modelu okołodźwiękowego przepływu pary przez palisadę turbinową.
PublicationWystępowanie skośnej fali uderzeniowej w przepływie pary przez palisadę turbinową stanowi zagrożenie dla bezpiecznej pracy turbiny oraz dla jej elementów konstrukcyjnych. Detekcja oraz lokalizacja fali uderzeniowej, a także rozpoznanie przyczyny jej powstawania, nie są możliwe do osiągnięcia na drodze pomiarowej. Analizę zjawisk zachodzących wewnątrz kanału przepływowego umożliwiają natomiast modele numeryczne oraz neuronowe. Zaletą...
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A numerical model to simulate the motion of a lifesaving module during its launching from the ship’s stern ramp
PublicationThe article presents a numerical model of object motion in six degrees of freedom (DoF) which is intended to be used to simulate 3D motion of a lifesaving module during its launching from a ship using a stern ramp in rough sea. The model, of relatively high complexity, takes into account both the motion of the ship on water in changing sea conditions, and the relative motion of the ramp with respect to the ship. The motion of the...
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NOWELE
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The bioactivity of processed garlic (Allium sativum L.) as shown in vitro and in vivo studies on rats
PublicationCzosnek w trakcie procesu obróbki traci znaczną część swojej bioaktywności. Właściwości przeciwutleniające zmierzone metodą FRAP i DPPH stwierdzono na najwyższym poziomie w przypadku czosnku surowego oraz po krótkim okresie gotowania. Badania na szczurach poddanych diecie z dodatkiem krótkogotowanego czosnku potwierdziły, że proces ten nie zaburza właściwości przeciwutleniających surowego czosnku. U zwierząt stwierdzono poprawę...
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Hybrid of Neural Networks and Hidden Markov Models as a modern approach to speech recognition systems
PublicationThe aim of this paper is to present a hybrid algorithm that combines the advantages ofartificial neural networks and hidden Markov models in speech recognition for control purpos-es. The scope of the paper includes review of currently used solutions, description and analysis of implementation of selected artificial neural network (NN) structures and hidden Markov mod-els (HMM). The main part of the paper consists of a description...
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Recent advances in traffic optimisation: systematic literature review of modern models, methods and algorithms
PublicationOver the past few decades, the increasing number of vehicles and imperfect road traffic management have been sources of congestion in cities and reasons for deteriorating health of its inhabitants. With the help of computer simulations, transport engineers optimise and improve the capacity of city streets. However, with an enormous number of possible simulation types, it is difficult to grasp valuable, innovative solutions which...
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Journal of Modern Science
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Jaroslaw Spychala dr
PeopleOprócz bardzo dobrego wykształcenia osoba posiada również wieloletnie doświadczenie zawodowe, które jest poświadczeniem tego, że potrafi wykorzystać swoją wiedzę teoretyczną w praktycznych działaniach. Doświadczenie zawodowe jest bardzo bogate i rozbudowane. Ze względu na nabyte całkiem nowe umiejętności zwiększa się atrakcyjność doświadczonego pracownika. Są to między innymi kreatywne myślenie, zorientowanie na cel, odporność...
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Bioactive silica-based drug delivery systems containing doxorubicin hydrochloride: In vitro studies
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Lobularia libyca: Phytochemical Profiling, Antioxidant and Antimicrobial Activity Using In Vitro and In Silico Studies
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An In Vitro Antimicrobial, Anticancer and Antioxidant Activity of N–[(2–Arylmethylthio)phenylsulfonyl]cinnamamide Derivatives
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Antimicrobial photodynamic therapy with fulleropyrrolidine: photoinactivation mechanism of Staphylococcus aureus, in vitro and in vivo studies
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Assessment of phase stability and in vitro biological properties of hydroxyapatite coatings composed of hexagonal rods
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Morphogenesis-related gene-expression profile in porcine oocytes before and after in vitro maturation
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Expression of INHβA and INHβB proteins in porcine oocytes cultured in vitro is dependent on the follicle size
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublicationA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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Bioactive peptides from beef products fermented by acid whey – in vitro and in silico study
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In vitro photodynamic activity of lipid vesicles with zinc phthalocyanine derivative against Enterococcus faecalis
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Characterization of In Vitro and In Vivo Metabolism of Antazoline Using Liquid Chromatography-Tandem Mass Spectrometry
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In vitro antioxidant, anti-inflammatory activities and acetylcholinesterase inhibition properties of selected plant extracts
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In vitro evaluation of the effect of Bidens tripartita extract and its main constituents on the intestine contractility
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THE EFFECTIVENESS OF DISINFECTION METHODS ON GERMINATION OF GOJI SEEDS (Lycium barbarum L.) IN IN VITRO CULTURE
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In Vitro Antiproliferative and Antioxidant Effects of Extracts from Rubus caesius Leaves and Their Quality Evaluation
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Flavonoids and Essential Oil of Bidens cernua of Polish Origin and in Vitro Antimicrobial Activity of the Oil
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ALLEVIATING EFFECTS OF ASCORBIC ACID ON LEAD TOXICITY IN GOJI (Lycium barbarum L.) IN VITRO
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Assessment of the glycaemic index, content of bioactive compounds, and their in vitro bioaccessibility in oat-buckwheat breads
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In vitro fermentation of new modified starch preparations—changes of microstructure and bacterial end-products
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Stimulation of antibacterial napthoquinones and flavonoids accumulation in carnivorous plants grown in vitro by addition of elicitors
PublicationRośliny owadożerne (D. muscipula, D. capensis) zawierają dwie grupy farmakologicznie czynnych substancji - naftochinony: plumbagina, ramentaceon, oraz flawonoidy: kwercetyna i mirycetyna. Na wzrost akumulacji tychże substancji w tkankach roślin owadożernych ma wpływ dodatek elicytora. Zbadano wpływ następujących elicytorów na zawartość metabolitów o znaczeniu farmaceutycznym: kwas jaśminowy oraz lizat Agrobacterium rhizogenes....
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Modifications of silicate bioglass synthesis and composition for in vitro dissolution control: Static and dynamic assessment
PublicationA set of fifteen calcium-phosphate-silicate glass samples, varying in alkali, magnesium, silicon, and nitrogen content, was prepared, and their structural, thermal, and in vitro dissolution properties were analyzed. Infrared spectroscopy showed a high degree of depolymerization of the silicate network consisting mainly of Q2 and Q3 units. Thermal analysis showed that the silicon content primarily affects both the glass transition...
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Degradibility in vitro of polyurethanes based on synthetic atactic poly[)R,S)-3-hydroxybutyrate
PublicationThe aim of the paper was to determine the degradibility of aliphatic polyurethanes in hydrolytic and oxidative solutions. DSC, GPC, density, polymer surface morphology were studied.