Search results for: Emotiv Epoc
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Molecular dynamics simulations reveal the balance of forces governing the formation of a guanine tetrad—a common structural unit of G-quadruplex DNA
PublicationG-quadruplexes (G4) are nucleic acid conformations of guanine-rich sequences, in which guanines are arranged in the square-planar G-tetrads, stacked on one another. G4 motifs form in vivo and are implicated in regulation of such processes as gene expression and chromosome maintenance. The structure and stability of various G4 topologies were determined experimentally; however, the driving forces for their formation are not fully...
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Mariusz Figurski prof. dr hab. inż.
PeopleMariusz Józef Figurski (born 27 April 1964 in Łasinie, Poland) - Polish geodesist, professor of technical sciences, professor at the Gdańsk University of Technology. Early life and education He passed the matriculation examination in 1983 after he had finished Jan III Sobieski High school in Grudziądz. He graduated the Military University of Technology on an individual mode at the Faculty of Electromechanics and Civil Engineering...
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Telomere uncapping by common oxidative guanine lesions: Insights from atomistic models
PublicationOxidative damage to DNA is widely known to contribute to aging and disease. This relationship has been extensively studied for telomeres – structures that cap chromosome ends – due to their role in cell proliferation and senescence, and exceptional susceptibility to oxidation. Indeed, the repetitive telomeric DNA sequence contains the 5′-GGG-3′ motif that has the lowest ionization potential of all trinucleotides. Accordingly, experiments...
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Lead(II) coordination polymers with imidazole-4- and pyrazole-3-carboxylate isomeric linkers: Structural diversity and luminescence properties
PublicationUsing 1H-imidazole-4-carboxylic acid (4imCOOH) and 1H-pyrazole-3-carboxylic acid (3pyrCOOH) coordination polymers [Pb(4imCOO)2(H2O)]n (1) and [Pb2(3pyrCOO)4]n (2) were constructed. Obtained polymers were characterized via FT-IR, X-ray, PL and TG methods. The coordination polyhedron around Pb(II) in 1 is described as distorted pentagonal pyramid with hemidirected coordination sphere (based on DFT calculations). Compound 2 consists...
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Pantographic metamaterials: an example of mathematically driven design and of its technological challenges
PublicationIn this paper, we account for the research efforts that have been started, for some among us, already since 2003, and aimed to the design of a class of exotic architectured, optimized (meta) materials. At the first stage of these efforts, as it often happens, the research was based on the results of mathematical investigations. The problem to be solved was stated as follows: determine the material (micro)structure governed by those...
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Robot-Based Intervention for Children With Autism Spectrum Disorder: A Systematic Literature Review
PublicationChildren with autism spectrum disorder (ASD) have deficits in the socio-communicative domain and frequently face severe difficulties in the recognition and expression of emotions. Existing literature suggested that children with ASD benefit from robot-based interventions. However, studies varied considerably in participant characteristics, applied robots, and trained skills. Here, we reviewed robot-based interventions targeting...
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Self Portrait with a Mask
PublicationPaweł SASIN - Self Portrait with a Mask “Every work of art is the child of its time, and, in many cases, the mother of our emotions. “ Wassily Kandynsky, Concerning the Spiritual in Art The two years 2020 and 2021 were marked by the COVID-19 pandemic – a lengthy period of time in which everyone felt in danger of losing one’s health or life. As a result, many people were experiencing negative emotion, becoming subject to psychological...
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How can the work environment be redesigned to enhance the well-being of individuals with autism?
PublicationPurpose – This article examines the opportunities to create optimal conditions for individuals with autism, to work successfully within the contemporary workplace and improve their well-being. These opportunities arise from digital technology (DT) development, enabling the work environment to be remodeled by providing new possibilities and ways of working. The author discusses both technology-based as well as non-technological accommodations...
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Light‐Driven Multi‐Charge Separation in a Push‐Pull Ruthenium‐Based Photosensitizer – Assessed by RASSCF and TDDFT Simulations
PublicationThe performance of photosensitizers in the field of, for example, solar energy conversion, relies on their light-harvesting efficiency in the visible region, population of long-lived charge separated intermediates, as well as their charge-accumulation capacity amongst other properties. In this computational study, we investigate the photophysical properties of a bis(bipyridyl)ruthenium(II)-based black dye (Ru) incorporating a chromophoric...
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Interactions of telomeric proteins with nucleic acids: sequence recognition on intact and oxidatively damaged telomeres
PublicationTelomeres are complex nucleoprotein assemblies that play a vital role in the maintenance of functional ends of linear chromosomes. Telomeric DNA, composed of tandem repeats of the 5'-TTAGGG-3' motif, solves the so-called end replication problem: as chromosomes shorten with each cell division, no information is lost, and the telomere can be re-extended. In the cell, many protein factors regulate telomere length, nuclear positioning...
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Tomasz Deręgowski dr inż.
PeopleTomasz Deręgowski is Assistant Professor at the Department of Informatics in Management, Faculty of Management and Economics, Gdańsk University of Technology, Poland, and Head of Data Platform Engineering Department, working on Big Data, Machine Learning and Data Science solutions at Nordea Bank AB - the largest Scandinavian financial institution. He has more than 15 years of industrial experience, working as a programmer, team...
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The structurally similar TRFH domain of TRF1 and TRF2 dimers shows distinct behaviour towards TIN2
PublicationThe telomere repeat binding-factor 1 and 2 (TRF1 and TRF2) proteins of the shelterin complex bind to duplex telomeric DNA as homodimers, and the homodimerization is mediated by their TRFH (TRF-homology) domains. We performed molecular dynamic (MD) simulations of the dimer forms of TRF1TRFH and TRF2TRFH in the presence/absence of the TIN2TBM (TIN2, TRF-interacting nuclear protein 2, TBM, TRF-binding motif) peptide. The MD results...
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Effect of Aromatic System Expansion on Crystal Structures of 1,2,5-Thia- and 1,2,5-Selenadiazoles and Their Quaternary Salts: Synthesis, Structure, and Spectroscopic Properties
PublicationRational manipulation of secondary bonding interactions is a crucial factor in the construction of new chalcogenadiazole-based materials. This article reports detailed experimental studies on phenanthro[9,10-c][1,2,5]chalcogenadiazolium and 2,1,3-benzochalcogenadiazolium salts and their precursors. The compounds were synthesized, characterized employing NMR and UV-Vis spectroscopy. TD-DFT calculations were also performed. The influence...
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Automatic recognition of males and females among web browser users based on behavioural patterns of peripherals usage
PublicationPurpose The purpose of this paper is to answer the question whether it is possible to recognise the gender of a web browser user on the basis of keystroke dynamics and mouse movements. Design/methodology/approach An experiment was organised in order to track mouse and keyboard usage using a special web browser plug-in. After collecting the data, a number of parameters describing the users’ keystrokes, mouse movements and clicks...
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Overview of planar antenna loading metamaterials for gain performance enhancement: the two decades of progress
PublicationMetamaterials (MTMs) are artificially engineered materials with unique electromagnetic properties not occurring in natural materials. MTMs have gained considerable attention owing to their exotic electromagnetic characteristics such as negative permittivity and permeability, thereby a negative refraction index. These extraordinary properties enable many practical applications such as super-lenses, and cloaking technology, and are...
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Noise Generated by Tyres Designet for Electric Vehicles - Results of Laboratory Experiments
PublicationA few years ago, electric and hybrid vehicles were rarely seen on public roads and were considered more as exotic curiosities or even as a sign of extravagance than a practical means of transport. Nowadays the situation has changes significantly. This was caused both by the technical development and legislative actions, as well as the organizational nature promoting the purchace and use of low emission vehicles. Electric vehicles...
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Cloning, expression, and biochemical characterization of a coldactive GDSL-esterase of a Pseudomonas sp. S9 isolated from Spitsbergen island soil
PublicationAn estS9 gene, encoding an esterase of the psychrotolerant bacterium Pseudomonas sp. S9 was cloned and sequenced. The deduced sequence revealed a protein of 636 amino acid residues with a molecular mass of 69 kDa.Further amino acid sequence analysis revealed that the EstS9 enzyme contained a G-D-S-L motif centered at a catalytic serine, an N-terminal catalytic domain and a C-terminal autotransporter domain. Two recombinant E. coli...
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Iron–Sulfur Cluster Biogenesis Chaperones: Evidence for Emergence of Mutational Robustness of a Highly Specific Protein–Protein Interaction
PublicationBiogenesis of iron–sulfur clusters (FeS) is a highly conserved process involving Hsp70 and J-protein chaperones. However, Hsp70 specialization differs among species. In most eukaryotes, including Schizosaccharomyces pombe, FeS biogenesis involves interaction between the J-protein Jac1 and the multifunctional Hsp70 Ssc1. But, in Saccharomyces cerevisiae and closely related species, Jac1 interacts with the specialized Hsp70 Ssq1,...
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Experimental and theoretical studies on the Sulfamethazine-Urea and Sulfamethizole-Urea solid-liquid equilibria
PublicationThe miscibility of active pharmaceutical ingredients with excipients is an important aspect in pharmaceutical technology protocols. In this study, the differential scanning calorimetry (DSC) was used for Sulfamethazine-Urea (SI–U) and Sulfamethizole-Urea (SO–U) solid-liquid phase diagrams determination. Both sulfonamides form simple binary eutectics with Urea. The lack of new co-crystal phase formation was confirmed by inspection...
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Stereoselective Alkylation of Indole with 5-Arylidene-Meldrum’s Acids in the Presence of Organocatalysts
PublicationBackground: Indole motif is frequently present in biologically active compounds. Enantiomerically pure or enriched 2,2-dimethyl-5-(aryl(1H-indol-3-yl)methyl)-1,3-dioxane-4,6-diones can be considered as a convenient starting point for the synthesis of a indole ring fused with cyclic ketones with biological activity. Preparation of chiral 2,2-dimethyl-5-(aryl(1H-indol-3-yl)methyl)-1,3-dioxane- 4,6-diones requires the reaction of...
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IMAGE CORRELATION AS A TOLL FOR TRACKING FACIAL CHANGES CAUSING BY EXTERNAL STIMULI
PublicationExpressions of the human face bring a lot of information, which are a valuable source in the areas of computer vision, remote sensing and affective computing. For years, by analyzing the movement of the skin and facial muscles scientists are trying to create the perfect tool, based on image analysis, allowing the recognition of emotional states of human beings. To create a reliable algorithm, it is necessary to explore and examine...
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Release systems based on self-assembling RADA16-I hydrogels with a signal sequence which improves wound healing processes
PublicationSelf-assembling peptides can be used for the regeneration of severely damaged skin. They can act as scaffolds for skin cells and as a reservoir of active compounds, to accelerate scarless wound healing. To overcome repeated administration of peptides which accelerate healing, we report development of three new peptide biomaterials based on the RADA16-I hydrogel functionalized with a sequence (AAPV) cleaved by human neutrophil elastase...
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Representation of magnetic hysteresis in a circuit model of a single-phase transformer
PublicationThe paper presents a mathematical model for the hysteresis phenomenon in a multi-winding single-phase core type transformer. The set of loop differential equations was developed for K-th winding transformer model where the flux linkages of each winding includes a flux common Φ to all windings as function of magneto motive force Θ of all windings. The first purpose of this paper is to determine a hysteresis nonlinearity involved...
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Historia i Zabytki Techniki
e-Learning CoursesCel przedmiotuWprowadzenie studentów w powszechną historię techniki z szerszym omówieniem wybranych dziedzin. Objaśnienie roli postępu technicznego jako kluczowego czynnika rozwoju ludzkości. Dyskusja kontrowersji, wątpliwości oraz etycznych i ekologicznych aspektów postępu. Uwrażliwienie na wartość dziedzictwa, jego rolę kulturotwórczą i konieczność ochrony. Zapoznane z formalno-prawnymi i praktycznymi zagadnieniami ochrony zabytków...
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Historia Architektury Powszechnej II 2022/2023
e-Learning CoursesKURS HISTORII ARCHITEKTURY POWSZECHNEJ II (HAPow II) jest kursem obowiązkowym na 2 semestrze studiów I stopnia (inżynierskich) na Wydziale Architektury PG. Trwa cały semestr i zakończony jest egzaminem. Składa się z piętnastu jednogodzinnych wykładów oraz siedmiu odbywających się co 2 tygodnie dwugodzinnych ćwiczeń. Tematyka kursu obejmuje historię architektury świata zachodniego w epoce Nowożytności, począwszy od czasów renesansu...
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Impact of the anion and chalcogen on the crystal structure and properties of 4,6-dimethyl-2-pyrimido(thio)nium halides
PublicationBy the reaction of urea or thiourea, acetylacetone and hydrogen halide (HF, HBr or HI), we have obtained seven new 4,6-dimethyl-2-pyrimido(thio)nium salts, which were characterized by single-crystal X-ray diffraction, namely, 4,6-dimethyl-2-oxo-2,3-dihydropyrimidin-1-ium bifluoride, C₆H₉N₂O⁺·HF₂⁻ or (dmpH)F₂H, 4,6-dimethyl-2-oxo-2,3-dihydropyrimidin-1-ium bromide, C₆H₉N₂O⁺·Br⁻ or (dmpH)Br, 4,6-dimethyl-2-oxo-2,3-dihydropyrimidin-1-ium...
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Podejście topologiczne w architekturze na przełomie wieków XX/XXI.
PublicationJedną z immanentnych cech architektury jest zmienność. Na przestrzeni wieków wyrażała się ona głównie poprzez przebudowy i modernizacje istniejących budowli, które z biegiem czasu ulegały procesowi degradacji. Budowla zazwyczaj postrzegana była jako element stabilny, trwały, niekiedy wręcz monumentalny. Wraz z rewolucją przemysłową otworzyły się nowe możliwości techniczne i materiałowe dla budownictwa, co pociągnęło za sobą również...
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A set of data constituting the basis for the publication entitled "Mitochondria dysfunction is one of the causes of diclofenac toxicity in the green alga Chlamydomonas reinhardtii"
Open Research DataNon-steroidal anti-inflammatory drugs (NSAIDs), such as diclofenac (DCF), form a significant group of environmental contaminants. When the toxic effects of DCF on plants are analyzed, authors often focus on photosynthesis, whilemitochondrial respiration is usually overlooked. Therefore, an in vivo investigation of plant mitochondria functioning under...
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Architektura a dekonstrukcja. Przypadek Petera Eisenmana i Bernarda Tschumiego
PublicationArchitecture and Deconstruction Case of Peter Eisenman and Bernard Tschumi Introduction Towards deconstruction in architecture Intensive relations between philosophical deconstruction and architecture, which were present in the late 1980s and early 1990s, belong to the past and therefore may be described from a greater than...