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Search results for: LYSINE AUXOTROPHY
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Consequences of lysine auxotrophy for Candida albicans adherence and biofilm formation
PublicationA number of factors are known to be involved in Candida albicans virulence, although biofilm development on the surfaces of indwelling medical devices is considered to promote superficial or systemic disease. Based on previously reported up-regulation of saccharopine and acetyllysine in biofilm cells and activation of the lysine biosynthesis/degradation pathway, we investigated...
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Biological and Physico-Chemical Characteristics of Arginine-Rich Peptide Gemini Surfactants with Lysine and Cystine Spacers
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Enzymes of the lysine biosynthetic pathway as targets for antifungals ?
PublicationSystemic infections caused by human pathogenic fungi in immunocompromized patients continue to be one of the important clinical problems. Limited availability of safe and efficacious antifungal chemotherapeutics and emerging resistance to existing drugs stimulates search for novel molecular targets for antifungals. The α-aminoadipate pathway (AAP) of L-lysine biosynthesis is unique in fungi and thus has been so far considered...
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Stability of oil/water (ethanol, lysozyme or lysine) emulsions
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Effect of pH on optical sensing with poly-L-lysine-modified nanodiamonds
PublicationNitrogen-vacancy (NV) centers are crystallographic defects which provide diamonds with unique physical properties. The centers are known for their intensive, time-stable fluorescence, and an electron spin, which exhibits long coherence time and may be manipulated using external stimuli. Nanodiamonds containing the NV centers are promising tools in biolabeling, biosensing, and drug delivery due to the aforementioned properties of...
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Modulation of TET2 Activity By Ascorbic Acid and Factors Affecting Lysine Acetylation
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Synthesis of linear tuftsin analogues modified at the epsilon-amino group of lysine
PublicationZsyntetyzowano na fazie stałej nowe analogi tuftsyny i retro-tuftsyny zawierające wiązanie isopeptydowe na epsilon-aminowej grupie lizyny jako potencjalne immunostymulatory. Do syntezy wykorzystano standardową procedurę Fmoc. Po zdjęciu osłon kwasem TFA końcowe związki były oczyszczane, liofilizowane i charakteryzowane: MS, HPLC i NMR.
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Lipid oxidation and lysine availability in Atlantic mackerel hot smoked in mild conditions.
PublicationZawartość nadtlenków w wędzonych makrelach była o 50% mniejsza, a liczba anizydynowa 2,5 razy większa niż w surowych rybach. Przechowywanie ryb wędzonych w temp. +2C nie wpłynęło na zawartość produktów utlenienia lipidów. Zawartość dostępnej lizyny była podobna w surowych i wędzonych rybach. Skóra ryb wędzonych zawierała 2 razy więcej fenoli niż tkanka mięśniowa.
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Lipid oxidation and lysine availability in smoked Atlantic mackerel fillets and Baltic sprats.
PublicationNie wykazano korelacji między stopniem utlenienia lipidów a ich zawartością w rozmrożonych filetach makreli. Gorące i zimne wędzenie nie wływało na liczbę nadtlenkową w mięsie filetów makreli, natomiast w mięsie wędzonych szprotów była ona znacznie mniejsza niż w rybach surowych. Wędzenie nie powodowało obniżenia dostępnej lizyny, chociaż liczba anizydynowa zwiększyła się dwukrotnie w wędzonych filetach makreli i czterokrotnie...
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Developments in the synthesis and biological activity of Glycyl-L-Histydyl-L-Lysine derivatives
PublicationWe emphasize on the methods of the synthesis described in the literature and present the aspects of Gly-His-Lys structure modifications that played a key role in scientific research.
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Synthesis, Pharmacological Evaluation, and Computational Studies of Cyclic Opioid Peptidomimetics Containing β3-Lysine
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Cinemas d Amerique Latine
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Geoambiente On-line
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Bottom Line
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Ciceroniana On Line
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Poly-L-Lysine-modified boron-doped diamond electrodes for the amperometric detection of nucleic acid bases
PublicationBoron-doped diamond (BDD) is a very promising supporting material used in the construction of biosensors for molecular recognition. The direct immobilization of structurally-organized huge molecules, such as poly-L-Lysine (PLL) provides the possibility of determining organic molecules, e.g. nucleic acid bases (e.g. adenine, guanine) or peptides and proteins. This paper describes the direct method for chemical and electrochemical...
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Lifelong Learning in Europe (LLinE)
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Phages and engineered lysins as an effective tool to combat Gram‐negative foodborne pathogens
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Poly-L-Lysine-functionalized fluorescent diamond particles: pH triggered fluorescence enhancement via surface charge modulation
PublicationRecently, the interest in applying fluorescent diamond particles (FDPs) containing nitrogen-vacancy (NV) centers for enhancing the mechanical and chemical properties of some materials, biological imaging, and sensing has been expanding rapidly. The unique properties of NV centers such as intensive, time-stable fluorescence, and an electron spin, which exhibits long coherence time and may be manipulated using external stimuli, such...
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Image Processing On Line
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Phenotypic consequences of LYS4 gene disruption in Candida albicans
PublicationA BLAST search of the Candida Genome Database with the Saccharomyces cerevisiae LYS4 sequence known to encode homoaconitase (HA) revealed ORFs 19.3846 and 19.11327. Both alleles of the LYS4 gene were sequentially disrupted in Candida albicans BWP17 cells using PCR-based methodology. The null lys4Δ mutant exhibited lysine auxotrophy in minimal medium but was able to grow in the presence of L-Lys and α-aminoadipate, an intermediate...
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On-Line Partitioning for On-Line Scheduling with Resource Conflicts
PublicationWithin this paper, we consider the problem of on-line partitioning the sequence of jobs which are competing for non-sharable resources. As a result of partitioning we get the subsets of jobs that form separate instances of the on-line scheduling problem. The objective is to generate a partition into the minimum number of instances such that the response time of any job in each instance is bounded by a given constant. Our research...
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Lasing modes of infinite periodic chain of quantum wires
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Branched Poly(l-lysine)-Derived Nitrogen-Containing Porous Carbon Flake as the Metal-Free Electrocatalyst toward Efficient Oxygen Reduction Reaction
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Numerical study of lasing modes of periodically structured active nanowires
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Dipole-Bound Anions of Glycine Based on the Zwitterion and Neutral Structures
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Characteristic equations for the lasing modes of infinite periodic chain of quantum wires
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Low-threshold lasing eigenmodes of an infinite periodic chain of quantum wires
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Thresholds of Lasing as Solutions of Characteristic Equation for a VCSEL-type Layered Structure
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Lasing thresholds of plasmon and grating modes of coated silver nanowire gratings
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Optical theorem helps understand thresholds of lasing in open semiconductor microcavities
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Optical Theorem Helps Understand Thresholds of Lasing in Microcavities With Active Regions
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Ultrastructural and antioxidative changes in lupine embryo axes in response to salt stress
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Ascorbate and glutathione metabolism in embryo axes and cotyledons of germinating lupine seeds
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Lupine embryo axes under salinity stress. I. Ultrastructural response
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wystawa indywidualna 'dom w lesie. kaszubskie schronienie'
PublicationObiekt architektoniczny wyrasta i wrasta. To kolejno po sobie następujące etapy naturalnego rozwoju procesu zamieszkiwania. Poszukiwanie schronienia wynika z potrzeby i konieczności zapewnienia sobie bezpiecznej kryjówki. Nie tylko człowiek jej szuka. Metaforyczne wyobrażenia archetypicznej formy schronienia pokazują jej adaptowalność do różnorodnych uwarunkowań. Kontekst stanowi zadanie problemowe, na które odpowiedzią jest konkretna...
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Effect of polyvalent bacterial lysate on the clinical course of pollen allergic rhinitis in children
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Ultralow lasing thresholds of VCSEL-type resonators with periodically structured quantum wells
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Lupine embryo axes under salinity stress. II. Mitochondrial proteome response
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Differential response of antioxidative enzymes in embryonic axes and cotyledons of germinating lupine seeds
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Stable and degradable microgels linked with cystine for storing and environmentally triggered release of drugs
PublicationEnvironmentally sensitive, degradable microgels based on poly(N-isopropylacrylamide) (pNIPA) crosslinked with the diacryloyl derivative of cystine (BISS) were synthesized by applying surfactant-free emulsion polymerization. pNIPA contributed the sensitivity to temperature to the microgels and the cross-linker made them degradable and sensitive to pH. The morphology of the microgels was investigated by using scanning and transmission...
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On-line ranking of split graphs
PublicationA vertex ranking of a graph G is an assignment of positive integers (colors) to the vertices of G such that each path connecting two vertices of the same color contains a vertex of a higher color. Our main goal is to find a vertex ranking using as few colors as possible. Considering on-line algorithms for vertex ranking of split graphs, we prove that the worst case ratio of the number of colors used by any on-line ranking algorithm...
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A sine wave delay estimator
PublicationZaprezentowano nowe rozwiązanie dyskretno-czasowego estymatora ułamkowego opóźnienia sygnału sinusoidalnego, działające w systemie z otwartą pętlą sprzężenia zwrotnego. Proponowane rozwiązanie wykorzystuje koncepcję transformowania za pomocą filtru Hilberta sygnału referencyjnego celem estymacji różnicy fazy tego sygnału względem zaszumionego sygnału odebranego o znormalizowanej (względem okresu próbkowania) częstotliwości - bardzo...
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On-line P-coloring of graphs
PublicationFor a given induced hereditary property P, a P-coloring of a graph G is an assignment of one color to each vertex such that the subgraphs induced by each of the color classes have property P. We consider the effectiveness of on-line P-coloring algorithms and give the generalizations and extensions of selected results known for on-line proper coloring algorithms. We prove a linear lower bound for the performance guarantee function...
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The ORBIT bleeding score is associated with lysis and permeability of fibrin clots
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Stosunki wodne w obumierającym lesie świerkowym w Karkonoszach
PublicationObumieranie lasów w Karkonoszach związane jest z drastycznym obniżeniem pH w glebach w wyniku kwaśnych deszczów. Sadzonki świerkowe przeżywają tylko wtedy, kiedy trafiają na lokalne lepiej odwodnione wyniesienia terenowe. W wyniku obliczeń komputerowych programem SPAC uzyskano wskaźnik transpiracji na poziomie 2,9 mm/dobę, jednakże przy uszkodzonej strefie korzeniowej transpiracja spadała do poziomu 1,1 mm/dobę, blokując fotosyntezę...
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Ship’s de-perming process using coils lying on seabed
PublicationA ship built from ferromagnetic steel disturbs the uniformity of the Earth’s magnetic field. Changes of ship’s signature are due to the magneto-mechanical interaction of the hull with the Earth’s magnetic field. The ship’s magnetic field can be detected by a magnetic naval mine. For this reason, the vessel has to be demagnetized. There are several methods of ship’s de-perming. The results of experimental and computer simulations...
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The adiabatic potentials of low-lying electronic states of the NaRb molecule
PublicationAdiabatic potential energy curves and spectroscopic constants have been calculated for the NaRb molecule. The results of ten states of the symmetry Σ+, six states of the symmetry Π, and two states of the symmetry Δ are obtained by the nonrelativistic quantum chemical method used with pseudopotentials describing the interaction of valence electrons with atomic cores. Analysis is based on a comparison with the results of other theoretical...
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Diagnostyka układu przecinania w systemie on-line i off-line - przegląd opracowań własnych.
PublicationDiagnostyka narzędzi i obrabiarek do przecinania drewna i tworzyw drzewnych jest istotnym elementem identyfikacji stanu technicznego i możliwości obróbkowych układów przecinania. Ocenę rzeczywistego stanu pił i pilarek mozna przeprowadzić m. in. przy użyciu układów opisanych w artykule, takich jak: przenośny system diagnostyczny PSD, urządzenie do automatycznego sprawdzania geometrii ostrzy pił tarczowych WKOPTar, system identyfikacji...
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Agris On-line Papers in Economics and Informatics
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