Search results for: boronic acids

• The Role of Electron Transfer in the Fragmentation of Phenyl and Cyclohexyl Boronic Acids

  Publication

  • A. Lozano
  • B. Pamplona
  • T. Kilich
  • M. Łabuda
  • M. Mendes
  • J. Pereira-da-Silva
  • G. García
  • P. Gois
  • F. Ferreira Da Silva
  • P. Limão-Vieira

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2019

  In this study, novel measurements of negative ion formation in neutral potassium-neutral boronic acid collisions are reported in electron transfer experiments. The fragmentation pattern of phenylboronic acid is comprehensively investigated for a wide range of collision energies, i.e., from 10 to 1000 eV in the laboratory frame, allowing some of the most relevant dissociation channels to be probed. These studies were performed in...

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• AMINO ACIDS

  Journals

  ISSN: 0939-4451 , eISSN: 1438-2199

• NUCLEIC ACIDS RESEARCH

  Journals

  ISSN: 0305-1048 , eISSN: 1362-4962

• Boron Difluoride Complexes of Carbamoyl Meldrum's Acids

  Publication

  • S. Makowiec
  • Ł. Ponikiewski
  • N. Pawelska

  - JOURNAL OF FLUORINE CHEMISTRY - Year 2012

  5-[Hydroxy(aryl/alkylamino)methylene]-2,2-dimethyl-1,3-dioxane-4,6-diones react with BF3•Et2O in mild conditions leading to the formation of boron difluoride complexes of carbamoyl Meldrum's acids. The X-ray structure has been obtained for one representative complex. The obtained new compounds are fairly stable at standard ambient conditions and easily isolable.

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• Journal of Amino Acids

  Journals

  ISSN: 2090-0104

• AIDS

  Journals

  ISSN: 0269-9370 , eISSN: 1473-5571

• Spectroscopic insight into supramolecular assemblies of boric acid derivatives and β-cyclodextrin

  Publication

  • A. Kasprzak
  • K. Borys
  • S. Molchanov
  • A. Adamczyk-Woźniak

  - Carbohydrate Polymers - Year 2018

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• Monomeric Triphosphinoboranes: Intramolecular Lewis Acid–Base Interactions between Boron and Phosphorus Atoms

  Publication

  • A. Ordyszewska
  • N. Szynkiewicz
  • J. Chojnacki
  • R. Grubba

  - INORGANIC CHEMISTRY - Year 2022

  Herein, we present the synthesis of the first fully characterized monomeric triphosphinoboranes. The simple reaction of boron tribromide with three equivalents of bulky lithium phosphide tBu2PLi yielded triphosphinoborane (tBu2P)3B. Triphosphinoboranes with diversified phosphanyl substituents were obtained via a two-step reaction, in which isolable bromodiphosphinoborane (tBu2P)2BBr is first formed and then reacts with one equivalent...

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• Novel Cell Permeable Polymers of N-Substituted L-2,3-Diaminopropionic Acid (DAPEGs) and Cellular Consequences of Their Interactions with Nucleic Acids

  Publication

  • A. Romanowska
  • K. Węgrzyn
  • K. Bury
  • E. Sikorska
  • A. Gnatek
  • A. Piwkowska
  • I. Konieczny
  • A. Lesner
  • M. Wysocka

  - International Journal of Molecular Sciences - Year 2021

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• Is the Fatty Acids Profile in Blood a Good Predictor of Liver Changes? Correlation of Fatty Acids Profile with Fatty Acids Content in the Liver

  Publication

  • D. Maciejewska
  • J. Palma
  • K. Dec
  • K. Skonieczna-Żydecka
  • I. Gutowska
  • M. Szczuko
  • K. Jakubczyk
  • E. Stachowska

  - Diagnostics - Year 2019

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• Chronic Illness

  Journals

  ISSN: 1742-3953 , eISSN: 1745-9206

• Chronic Stress

  Journals

  eISSN: 2470-5470

• Complexation of amino acids derivatives in water by calix[4]arene phosphonic acids

  Publication

  • J. Dziemidowicz
  • D. Witt
  • J. Rachoń

  - Journal of Inclusion Phenomena and Macrocyclic Chemistry - Year 2008

  Series of the calix[4]arene phosphonic acids with various substituents at the lower rim was synthesized. Complexing properties of these receptors towards methyl esters of six amino acids strongly depended on the calix[4]arene conformation flexibility. The complex formation processes were monitored using 1H NMR spectroscopy (deuterated phosphate buffer at pD 7.3, 22 oC) and association constant values were evaluated. Inherently...

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• AIDS REVIEWS

  Journals

  ISSN: 1139-6121 , eISSN: 1698-6997

• AIDS AND BEHAVIOR

  Journals

  ISSN: 1090-7165 , eISSN: 1573-3254

• Poly-L-Lysine-modified boron-doped diamond electrodes for the amperometric detection of nucleic acid bases

  Publication

  • P. Niedziałkowski
  • T. Ossowski
  • P. Zięba
  • A. Cirocka
  • P. Rochowski
  • S. J. Pogorzelski
  • J. Ryl
  • M. Sobaszek
  • R. Bogdanowicz

  - JOURNAL OF ELECTROANALYTICAL CHEMISTRY - Year 2015

  Boron-doped diamond (BDD) is a very promising supporting material used in the construction of biosensors for molecular recognition. The direct immobilization of structurally-organized huge molecules, such as poly-L-Lysine (PLL) provides the possibility of determining organic molecules, e.g. nucleic acid bases (e.g. adenine, guanine) or peptides and proteins. This paper describes the direct method for chemical and electrochemical...

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• Impedimetric sensing of α-amino acids driven by micro-patterned 1,8-Diazafluoren-9-one into titania- boron- doped maze-like nanocarbons

  Publication

  • M. Pierpaoli
  • A. Lewkowicz
  • B. Dec
  • M. Nadolska-Dawidowska
  • R. Bogdanowicz

  - SENSORS AND ACTUATORS B-CHEMICAL - Year 2022

  The development of impedimetric, non-faradaic label-free sensors for the detection of α-amino acids constitutes a trailblazing technology for the fast and inexpensive quantification of such biomarkers. Since α-amino acids, such as glycine and sarcosine, are basic constituents in biological processes, a variation in their concentration may be an indicator of cardiovascular diseases and metabolic disorders or neurological conditions....

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• NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

  Journals

  ISSN: 1525-7770 , eISSN: 1532-2335

• PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

  Journals

  ISSN: 0952-3278 , eISSN: 1532-2823

• Study on the concentration of acids by membrane distillation

  Publication

  • M. Tomaszewska
  • M. Gryta
  • A. Morawski

  - Journal of Membrane Science - Year 1995

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• Chirality Measures of α-Amino Acids

  Publication

  • M. Jamróz
  • J. Rode
  • S. Ostrowski
  • P. Lipiński
  • J. Dobrowolski

  - Journal of Chemical Information and Modeling - Year 2012

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• Chlorogenic acids – their properties, occurrence and analysis

  Publication

  • M. Gil
  • D. WIANOWSKA

  - Annales Universitatis Mariae Curie-Skłodowska, Sectio AA, Chemia - Year 2017

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• Chronic Orthostatic Intolerance

  Publication

  • K. Narkiewicz
  • V. Somers

  - CIRCULATION - Year 1998

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• Modification of Bacterial Cellulose with Quaternary Ammonium Compounds Based on Fatty Acids and Amino Acids and the Effect on Antimicrobial Activity

  Publication

  • A. Żywicka
  • K. Fijałkowski
  • A. Junka
  • J. Grzesiak
  • M. El

  - BIOMACROMOLECULES - Year 2018

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• Chronic Diseases in Canada

  Journals

  ISSN: 0228-8699

• Chronic Respiratory Disease

  Journals

  ISSN: 1479-9723 , eISSN: 1479-9731

• Preventing Chronic Disease

  Journals

  ISSN: 1545-1151

• Inhibitors of amino acids biosynthesis as antifungal agents

  Publication

  • K. Rząd
  • I. Gabriel

  - AMINO ACIDS - Year 2015

  Fungal microorganisms, including the human pathogenic yeast and filamentous fungi, are able to synthesize all proteinogenic amino acids, including nine that are essential for humans. A number of enzymes catalyzing particular steps of human-essential amino acid biosynthesis are fungi specific. Numerous studies have shown that auxotrophic mutants of human pathogenic fungi impaired in biosynthesis of particular amino acids exhibit...

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• Applications of Unnatural Amino Acids in Protease Probes

  Publication

  • I. Maluch
  • J. Czarna
  • M. Drag

  - Chemistry-An Asian Journal - Year 2019

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• AIDS Research and Treatment

  Journals

  ISSN: 2090-1240 , eISSN: 2090-1259

• Nucleic Acid Therapeutics

  Journals

  ISSN: 2159-3337 , eISSN: 2159-3345

• AIDS Research and Therapy

  Journals

  ISSN: 1742-6405

• AIDS EDUCATION AND PREVENTION

  Journals

  ISSN: 0899-9546 , eISSN: 1943-2755

• Open AIDS Journal

  Journals

  eISSN: 1874-6136

• AIDS policy & law

  Journals

  ISSN: 0887-1493

• Propensity of salicylamide and ethenzamide cocrystallization with aromatic carboxylic acids

  Publication

  • M. Przybyłek
  • D. Ziółkowska
  • K. Mroczyńska
  • P. Cysewski

  - EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES - Year 2016

  The cocrystallization of salicylamide (2-hydroxybenzamide, SMD) and ethenzamide (2-ethoxybenzamide, EMD) with aromatic carboxylic acids was examined both experimentally and theoretically. The supramolecular synthesis taking advantage of the droplet evaporative crystallization (DEC) technique was combined with powder diffraction and vibrational spectroscopy as the analytical tools. This led to identification of eleven new cocrystals...

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• Ion Chromatography in Environmental Analysis of Selected Organic Acids

  Publication

  • B. Zygmunt
  • M. Wasielewska
  • A. Banel

  - Year 2012

  Low molecular mass carboxylic acids (LCAs) occur in many environmental compartments dueto natural processes and human activity. When volatile and nonvolatile acids are to be monitored then liquidchromatography, including ion chromatography seems a method of choice. At high pH the acids are inionized form and can be separated as carboxylats by means of anion exchange chromatography. LCAs canalso be separated at low pH by ion exclusion...

• Biodegradability of modified emulsifiers - esters of polyols and fatty acids

  Publication

  • R. Tomczak-Wandzel
  • H. Szeląg

  - Year 2007

  Badano podatność na biodegradację wybranych emulgatorów estrów polioli i kwasów tłuszczowych przy użyciu testu zamkniętej butelki (OECD 301 D). Stwierdzono, że badane emulgatory nie mogą zostać uznane za łatwo ulegające biodegradacji. Najwyższy poziom rozkładu (57,3%) osiągnął emulgator C14Gna, najniższy (29,8%) AEGNa.

• Electric chips for rapid detection and quantification of nucleic acids

  Publication

  • M. Gabig-Ciminska
  • A. Holmgren
  • H. Andresen
  • K. Bundvig
  • M. Wümpelmann
  • J. Albers
  • R. Hintsche
  • A. Breitenstein
  • P. Neubauer
  • M. Los... and 6 others

  - BIOSENSORS & BIOELECTRONICS - Year 2004

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• Bile Acids: Key Players in Inflammatory Bowel Diseases?

  Publication

  • A. Kriaa
  • V. Mariaule
  • A. Jablaoui
  • S. Rhimi
  • H. Mkaouar
  • J. Hernandez
  • B. Korkmaz
  • A. Lesner
  • E. Maguin
  • A. Aghdassi
  • M. Rhimi

  - Cells - Year 2022

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• Fatty acids as molecular carriers in cleavable antifungal conjugates

  Publication

  • M. Nowak
  • A. S. Skwarecki
  • J. Pilch
  • J. Górska
  • P. Szweda
  • M. J. Milewska
  • S. Milewski

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Year 2023

  Conjugates composed of C2-18 fatty acid (FA) residues as a molecular carrier and 5-fluorocytosine (5-FC) as an active agent, released upon the action of intracellular esterases on the ester bond between FA and “trimethyl lock” intramolecular linker, demonstrate good in vitro activity against human pathogenic yeasts of Candida spp. The minimal inhibitory concentrations (MIC) values for the most active conjugates containing caprylic...

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• S-thioacyldithiophosphates in the synthesis of thiohydroxamic acids and O-thioacylhydroxylamines

  Publication

  • L. Doszczak
  • J. Rachoń

  - SYNTHESIS-STUTTGART - Year 2002

  Ditiofosforany tioacylu to trwałe, łatwo osiągalne z kwasów karboksylowych środki tioacylujące. Z powodu ich niskiej reaktywności wobec nukleofili tlenowych i wysokiej wobec nukleofili azotowych znalazły zastosowanie w syntezie kwasów tiohydroksamowych bezpośrednio z hydroksyloamin z niechronioną grupą hydroksylową. W przypadku dużej zawady przestrzennej można otrzymać O-tioacylohydroksyloaminy.

• Mechanism of the reaction of Lawesson's reagent with N-alkylhydroxamic acids

  Publication

  • W. Przychodzeń

  - Year 2005

  Identyfikacja fosforowych produktów powstających w reakcji kwasów hydroksamowych z odczynnikiem Lawessona pozwoliła ustalić mechanizm tytułowej reakcji. Wykorzystano w tym celu spektroskopię 31P NMR. Wzorce labilnych produktów otrzymano na niezależnej drodze syntetycznej lub przeprowadzono je w trwałe pochodne, które wyizolowano z mieszanin reakcyjnych. Produktem przejściowym badanej reakcji okazał się odpowiedni O-ditiofosfonylowany...

• Journal of Ovonic Research

  Journals

  ISSN: 1842-2403 , eISSN: 1584-9953

• Journal of Bionic Engineering

  Journals

  ISSN: 1672-6529 , eISSN: 2543-2141

• AIDS CARE-PSYCHOLOGICAL AND SOCIO-MEDICAL ASPECTS OF AIDS/HIV

  Journals

  ISSN: 0954-0121 , eISSN: 1360-0451

• The effect of trees in the road crown on road safety

  Publication

  • M. Budzyński

  - Year 2007

  W referacie przedstawiono problem występowania wypadków związanych z najechaniem na drzewo. Problem ten występuje w Polsce głównie w województwach północnych i zachodnich, co jest związane ze specyficznymi cechami sieci drogowej tego obszaru. Referat przedstawia negatywny wpływ drzew rosnących w koronie drogi na bezpieczeństwo ruchu drogowego oraz określa metody zapobiegania wypadkom związanym z najechaniem na drzewo. Ze względu...

• Synthesis and biological activity of mycophenolic acid-amino acid derivatives

  Publication

  • D. Iwaszkiewicz-Grześ
  • G. Cholewiński
  • A. Kot-Wasik
  • P. Trzonkowski
  • K. Dzierzbicka

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Year 2013

  In search of new immunosuppressants, mycophenolic acid (MPA) was coupled with amino acid methyl esters followed by hydrolysis to analogs bearing free carboxylic groups. The obtained compunds were tested in vitro as growth inhibitors of lymphoid cell line (Jurkat) and human peripheral blood mononuclear cells (PBMC) from healthy donors. According to obtained results recovering of free carboxylic group increased their activity. Additionally,...

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• Synthesis and biological activity of mycophenolic acid-amino acid derivatives

  Publication

  • D. Iwaszkiewicz-Grzes
  • G. Cholewinski
  • A. Kot-Wasik
  • P. Trzonkowski
  • K. Dzierzbicka

  - EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - Year 2013

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• Anticancer Properties of Amino Acid and Peptide Derivatives of Mycophenolic Acid

  Publication

  • A. Siebert
  • M. Deptuła
  • M. Cichorek
  • A. Ronowska
  • G. Cholewiński
  • J. Rachoń

  - Anti-Cancer Agents in Medicinal Chemistry - Year 2021

  Background: Although Mycophenolic Acid (MPA) is applied as prodrugs in clinic as an immunosuppressant, it also possesses anticancer activity. MPA acts as Inosine-5’-Monophosphate Dehydrogenase (IMPDH) inhibitor, where the carboxylic group at the end of the side chain interacts with Ser 276 of the enzyme via hydrogen bonds. Therefore, MPA derivatives with other polar groups indicated high inhibition too. On the other hand, potent...

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