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Year 2016
Year 2020
Year 2011
Year 2010
Year 2023
  • The novel sterilization device: the prototype testing
    Publication

    - Scientific Reports - Year 2023

    Currently, there are numerous methods that can be used to neutralize pathogens (i.e., devices, tools, or protective clothing), but the sterilizing agent must be selected so that it does not damage or change the properties of the material to which it is applied. Dry sterilization with hydrogen peroxide gas (VHP) in combination with UV-C radiation is well described and effective method of sterilization. This paper presents the design,...

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  • Total impact of oxidative stress genes on cardiovascular events—a 7-year follow-up study
    Publication

    - JOURNAL OF APPLIED GENETICS - Year 2023

    Cardiovascular (CV) events are the number one cause of lifetime disability and deaths worldwide. It is well known that traditional risk factors do not fully correlate with clinical outcomes; therefore, searching for other markers that would explain CV events occurrence seems essential. Of importance, one of the main factors at the origin of CV events is oxidative stress, causing inflammation and atherosclerotic plaque instability....

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Year 2014
Year 2018
Year 2013
  • The role of epigenetics in regeneration
    Publication

    Complex changes in chromatin structure and at the transcriptional level occur from the creation of a single parental gamete throughout fertilization, embryo development and the life of an adult organism. Epigenetic changes, such as methylation and hydroxymethylation of DNA or histone methylation and acetylation, are an important part of these processes. Epigenetic regulation has an essential influence on gene expression level. DNA...

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  • The usefulness of Toxoplasma gondii MIC1-MAG1-SAG1 chimeric antigen in the serodiagnosis of ovine toxoplasmosis

    Toxoplasmosis is a zoonotic disease caused by the protozoan Toxoplasma gondii, which infects humans and most warm-blooded animals throughout the world. Although human toxoplasmosis in healthy adults is usually asymptomatic, a serious disease can occur in the case of congenital infection and immunocompromised individuals. Among food animals, sheep, along with goats and pigs, possess the highest incidence of T. gondii cysts in meat,...

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  • Toxoplasma gondii recombinant antigens as tools for serodiagnosis of human toxoplasmosis: current status of studies

    Toxoplasma gondii is a parasitic protozoan which is the cause of toxoplasmosis. Although human toxoplasmosis in healthy adults is usually asymptomatic, serious disease can occur in the case of congenital infections and immunocompromised individuals. Furthermore, despite the exact recognition of its etiology, it still presents a diagnostic problem. Diagnosis of toxoplasmosis is mainly based on the results of serological tests detecting...

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  • Wybrane metody badania poziomu metylacji DNA w komórkach eukariotycznych
    Publication

    - Year 2013

    Metylacja regionów promotorowych jest jednym z głównych mechanizmów regulacji transkrypcji genów u eukariota. W komórkach ssaczych metylacja DNA zachodzi głównie na reszcie cytozyny występującej w dinukleotydach CpG i jest katalizowana przez metylotransferazy DNA (DNMT1, DNMT3A i DNMT3B) (Turek Plewa, Jagodziński 2005). Mapowanie 5 metylocytozyny w DNA genomowym jest jednym z narzędzi do badania wpływu metylacji na tkankowo-specyficzną...

Year 2019
Year 2022
Year 2007
Year 2021
Year 2006
Year 2008
Year 2015
Year 2017
  • Transcriptomic responses to wounding: meta-analysis of gene expression microarray data
    Publication

    - BMC GENOMICS - Year 2017

    Background A vast amount of microarray data on transcriptomic response to injury has been collected so far. We designed the analysis in order to identify the genes displaying significant changes in expression after wounding in different organisms and tissues. This meta-analysis is the first study to compare gene expression profiles in response to wounding in as different tissues as heart, liver, skin, bones, and spinal cord, and...

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  • WIELOLEKOOPORNE ZAKAŻENIA CANDIDA - PROBLEM XXI WIEKU!

    W ostatnich latach obserwuje się dramatyczny wzrost zakażeń grzybiczych, których przyczyną są grzyby z rodzaju Candida (C). Większość zakażeń wywoływana jest przez C. albicans, C. glabrata, C. krusei, C. parapsilosis i C. tropicalis. Dotychczas najczęściej stosowanymi lekami przeciwko Candida spp były azole, jednakże ze względu na występowanie naturalnej oporności na te antybiotyki (C. glabrata i C. krusei) coraz częściej azole...

Year 2009
Year 2004