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Wyniki wyszukiwania dla: human
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Evaluation of a new freezing protocol containing 20% dimethyl sulphoxide concentration to cryopreserve human ovarian tissue
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Interactions of Nitroaromatic Compounds with the Mammalian Selenoprotein Thioredoxin Reductase and the Relation to Induction of Apoptosis in Human Cancer Cells
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Inhibition of phthalocyanine-sensitized photohemolysis of human erythrocytes by polyphenolic antioxidants: description of quantitative structure–activity relationships
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Erratum to: Effects of flavonoids on expression of genes involved in cell cycle regulation and DNA replication in human fibroblasts
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LY294002 and sorafenib as inhibitors of intracellular survival pathways in the elimination of human glioma cells by programmed cell death
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Sequential induction of mitotic catastrophe followed by apoptosis in human leukemia MOLT4 cells by imidazoacridinone C-1311
PublikacjaWykazano, że pochodna imidazoakrydonu C-1311 indukuje zahamowanie progresji komórek MOLT4 w fazie G2M cyklu życiowego. Podwyższona ekspresja fosfoepitopu MPM-2 przy jednoczesnym zaniku ufosforylowanej formy Tyr15-cdc2 wskazywała, iż komórki początkowo zablokowane w fazie G2 przechodziły do mitozy. Jednocześnie na skutek nieprawidłowego przebiegu mitozy komórki ulegały katastrofie mitotycznej. Analiza biochenicznych markerów apoptozy...
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Synthesis and SAR Studies of Antibacterial Peptidyl Derivatives Based upon the Binding Site of Human Cystatin C
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Investigation of Iron and Zinc Concentrations in Human Milk in Correlation to Maternal Factors: An Observational Pilot Study in Poland
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Relation between polyphenols, malondialdehyde, antioxidant capacity, lactate dehydrogenase and toxic elements in human colostrum milk
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<p>Nanoparticles And Human Saliva: A Step Towards Drug Delivery Systems For Dental And Craniofacial Biomaterials</p>
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Independent dynamics of slow, intermediate, and fast intracranial EEG spectral activities during human memory formation
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Changes in the Thickness of Ice Cover on Water Bodies Subject to Human Pressure (Silesian Upland, Southern Poland)
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IL-33 and IL-4 impair barrier functions of human vascular endothelium via different mechanisms
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The effect of interleukin-35 on the integrity, ICAM-1 expression and apoptosis of human aortic smooth muscle cells
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Immunoscore, circulating tumor cells and human-derived organoids as potential predictive tools in personalized cancer medicine
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C-1305 inactivation of recombinant human cytochrome P450, CYP1A2 and CYP3A4, is due to mechanism-based inhibition
PublikacjaPodjęto próbę określenia mechanizmu obserwowanej inhibicji izoenzymów CYP1A2 i CYP3A4 przez pochodną triazoloakrydonu C-1305.W pierwszym kroku stwierdzono, że hamowanie aktywnosci obu enzymów jest procesem nieodwracalnym. W kolejnych etapach badań wykazano między innymi, że obecność NADPH zwiększa istotnie stopień obserwowanej inhibicji, co wskazało, że mamy do czynienia z inhibicją samobójczą opartą na mechanizmie działania (ang....
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Human movement analysis in evaluation of the risk of falls in younger and older workers while wearing protective footwear
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Biotransformation of abused synthetic cannabinoids, JWH-018 and JWH-073, by human cytochromes P450 and UDP-glucuronosyltransferases
PublikacjaZwiązki oznaczone symbolami JWH-018 i JWH-073 są syntetycznymi pochodnymi kanabinoidów, obecnymi w preparatach o działaniu psychoaktywnym (K2/Spice). Wcześniejsze badań wykazały, że u osób przyjmujących tzw. ''legalną marihuanę'', głównymi produktami biotransformacji obecnymi w moczu były hydroksylowe pochodne obu związków, jak również ich glukuronidy. W związku z tym celem prowadzonych badań było określenie roli poszczególnych...
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A FEM membrane model of human fascia-synthetic implant system in a case of a stiff ventral hernia orifice
PublikacjaPraca prezdstawia model matematyczny układu tkanka ludzka - implant syntetyczny w postaci tzw. siatki w leczeniu przepuklin brzusznych. Implant jest tu moelowany jako struktura membranowa. Ocena wpływu danych materiałowych oraz wstępnego napięcia na zachowanie pracującej membrany po implantacji została przedstawiona na podstawie analizy wrażliwości. Pracę podsumowują pewne wskazówki dla chirurgów implantujących siatki.
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The response of human colon cancer cells to C-1748 (4-methyl-1-nitroacridine derivative) treatment
PublikacjaPrzeprowadzone badania miały na celu określenie wpływu pochodnej 4-metylo-1-nitroakrydyny C-1748 na komórki ludzkiego raka okrężnicy HCT8 oraz HT29. Komórki obu linii, traktowane badanym związkiem, ulegały przede wszystkim apoptozie, przy czym liczba komórek apoptotycznych była znacznie większa w przypadku linii HCT8. Ponadto, proliferacja części komórek HCT8, została zahamowana w wyniku uruchomienia procesu starzenia, czego nie...
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Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease
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Yamogenin-Induced Cell Cycle Arrest, Oxidative Stress, and Apoptosis in Human Ovarian Cancer Cell Line
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Characterization and cytotoxic effect of aqua-(2,2′,2′′-nitrilotriacetato)-oxo-vanadium salts on human osteosarcoma cells
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Selected extracts from Potentilla alba modulate the viability of normal and cancerous cells of the human colon epithelium
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Potentilla alba Extracts Affect the Viability and Proliferation of Non-Cancerous and Cancerous Colon Human Epithelial Cells
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Anticancer potential of acetone extracts from selected Potentilla species against human colorectal cancer cells
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In Vitro Anticancer Potential of Jasione montana and Its Main Components against Human Amelanotic Melanoma Cells
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Antitumour imidazoacridone C-1311 induces cell death by mitotic catastrophe in human colon carcinoma cells
PublikacjaW przedstawionych badaniach określano mechanizm śmierci komórkowej indukowanej przez imidazoakrydon C-1311 (Symadex) w komórkach HT-29 ludzkiego raka jelita grubego, które wykazywały szczególną wrażliwość na ten związek w eksperymentalnych modelach in vitro i in vivo. Przy stężeniu odpowiadającemu dawce IC99, związek powodował zahamowanie progresji cyklu komórkowej w fazie S po czym następował blok w fazie G2. Po czasach 48-96...
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Influence of G2 arrest on the cytotoxicity of DNA topoisomerase inhibitorstoward human carcinoma cells with different p53 status
PublikacjaRola bloku G2 w efekcie cytotoksycznym inhibitorów DNA topoizomeraz w stosunku do ludzkich komórek rakowych różniących się funkcjonalnością białka p53.
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Badania poziomów zanieczyszczeń w płynach ustrojowych człowieka. Study of the level of pollution in human body fluids
PublikacjaŹródłem informacji o stanie środowiska mogą być zarówno wyniki badań próbek części nieożywionej (woda, gleba, powietrze) jak i próbki części biotycznej, w tym także tkanek i płynów ustrojowych człowieka, który jest nieustannie narażony na działanie szerokiego spektrum ksenobiotyków. W niniejszej pracy przedstawiono przegląd metod izolacji, wzbogacania i technik oznaczeń końcowych analitów z próbek moczu ludzkiego i krwi. Zawarto...
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New recombinant chimeric antigens, P35-MAG1, MIC1-ROP1, and MAG1-ROP1, for the serodiagnosis of human toxoplasmosis
PublikacjaThe aim of the study was to evaluate the usefulness of 3 chimeric Toxoplasma gondii antigens, P35-MAG1,MIC1-ROP1 andMAG1-ROP1, in the serodiagnosis of an acute toxoplasmosis in humans. Proteins were produced as fusion proteins containing His tags ends and then further purified by metal affinity chromatography. Their application for the diagnosis of recently acquired T. gondii infection was tested in IgG and IgM enzyme-linked immunosorbent...
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Cabbage Juices and Indoles Modulate the Expression Profile of AhR, ERα, and Nrf2 in Human Breast Cell Lines
PublikacjaOur previous studies showed the diversified effect of cabbage juices and indoles on the estrogen metabolism key enzymes (CYP1A1, CYP1A2, CYP1B1) in breast epithelial cells differing in ER status, i.e., in tumorigenic—MCF7, MDA-MB-231 and non-tumorigenic—MCF10A cells. The aim of the present study was to further investigate the mechanism of chemopreventive action of cabbage juice and its active components by evaluating their effect...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_004)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_005)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0010)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_002)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0012)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_008)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_003)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_007)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_006)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0011)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_009)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0017)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0021)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0020)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0019)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0024)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_0023)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...
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Robotics for human health and performance (PG_00054982) 04.2024
Kursy OnlineDuring this course students will be provided with the knowledge in areas of robotics and biomechanics necessary to design instrumentation for human health and performance, as well as about human-robot interface.