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Wavelet-based denoising method for real phonocardiography signal recorded by mobile devices in noisy environment
PublikacjaThe main obstacle in development of intelligent autodiagnosis medical systems based on the analysis of phonocardiography (PCG) signals is noise. The noise can be caused by digestive and respiration sounds, movements or even signals from the surrounding environment and it is characterized by wide frequency and intensity spectrum. This spectrum overlaps the heart tones spectrum, which makes the problem of PCG signal filtrating complex....
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APPLICATION OF ENTROPY-BASED METHODS TO DISTINGUISH HEALTHY INDIVIDUALS WITH NORMAL SINUS RHYTHM FROM PATIENTS WITH CONGESTIVE HEART FAILURE
PublikacjaIn this paper, we examined whether entropy-based methods are able to differentiate healthy individuals from patients with congestive heart failure. To this aim, we applied two methods: Permutation Entropy and Block Entropy. Long-term ECG recordings (75 000 RR intervals) were analyzed. The results proved that both methods can distinguish those groups on condition that the parameters are appropriately chosen.
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Smart Weighing Scale with Feet-Sampled ECG
PublikacjaIn a smart home, health and well-being monitoring systems could be embedded in everyday devices providing a pervasive care. A home bathroom scale is an example of such a device, typically used to measure body weight and very often its composition (e.g. body water/fat percentage). In this paper, we analyzed a potential use of the bathroom scale to measure electrocardiogram (ECG) from electrodes located on the scale's tile. In particular...
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QRS Morphology-Based EDR Signal—Factors Determining its Properties
PublikacjaRespiration-induced signals contain a clinically significant information. It could be obtained utilizing both direct and indirect methods. ECG-Derived Respiration (EDR) method is the latter one. However, in this case, two approaches could be distinguished. First one is based on determining changes in the morphology of QRS complexes while the second one is based on the Respiratory Sinus Arrhythmia (RSA) mechanism. The former approach...
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The Use of Wavelet Analysis to Denoising of Electrocardiography Signal
PublikacjaThe electrocardiography examination, due to its accessibility and simplicity, has an important role in diagnostics of the heart ailments. It enables quick detection of various heart defects, undetectable by other kinds of diagnostic tools, so it is very popular. Nevertheless, the measured signal is exposed to a different disturbances. Among them, the electromagnetic interferences, drift of reference electrode and high frequency...
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A scale with ECG measurements capability for home cardiac monitoring
PublikacjaPresented device -a scale developed for enabling extra measurements, in addition to body weight and composition, the electrical activity of the heart (electrocardiogram - ECG) and the level of oxygen saturation in the blood SaO2. Electrical activity is recorded in the form of six leads, socalled - limb leads. The device allows measurement of all standard limb leads and without the need for additional procedures. ECG, although the...
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Expert System and Decision Support System for Electrocardiogram Interpretation and Diagnosis: Review, Challenges and Research Directions
PublikacjaElectrocardiography (ECG) is one of the most widely used recordings in clinical medicine. ECG deals with the recording of electrical activity that is generated by the heart through the surface of the body. The electrical activity generated by the heart is measured using electrodes that are attached to the body surface. The use of ECG in the diagnosis and management of cardiovascular disease (CVD) has been in existence for over...
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Determination of time delay between ventricles contraction using impedance measurements
PublikacjaThe paper presents a novel approach to assessment of ventricular dyssynchrony basing on multichannel electrical impedance measurements. Using a proper placement of electrodes, the sensitivity approach allows estimating time difference between chambers contraction from over determined nonlinear system of equations. The theoretical considerations which include Finite Element Method simulations were verified using measurements on...
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Initial Report on Numerical Modeling of Blood Flow in Myocardial Bridge Region of Coronary Artery: Concept of Model Validation
PublikacjaThe paper presents a numerical method of blood flow simulation within the coronary artery covered by the myocardial bridge. The myocardial bridge is a congenital coronary abnormality caused by the blood vessel location under one of the heart muscles. In this case, the blood flow within the vessel is partially disturbed which can cause several consequences. The presented numerical simulation allowed us to estimate the blood flow...
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Retained features of embryonic metabolism in the adult MRL mouse
PublikacjaThe MRL mouse is an inbred laboratory strain that was derived by selective breeding in 1960 from the rapidly growing LG/J (Large) strain. MRL mice grow to nearly twice the size of other commonly used mouse strains, display uncommonly robust healing and regeneration properties, and express later onset autoimmune traits similar to Systemic Lupus Erythematosis. The regeneration trait (heal) in the MRL mouse maps to 14-20 quantitative...
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Mercury concentration and the absolute and relative sizes of the internal organs in cormorants Phalacrocorax carbo (L. 1758) from the breeding colony by the Vistula Lagoon (Poland)
PublikacjaThis work analyses the effect of mercury on the condition of cormorants (Phalacrocorax carbo) from an extensive breeding colony in northern Poland, the largest in Europe. A total of 55 birds (44 adults and 11 immature) were obtained. Total mercury (Hg) concentrations were measured in the liver, kidneys, breast muscles, heart, gullet (oesophagus), stomach, intestines, trachea, lungs and eyeballs. The total body mass (TBM) and empty...
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Optimal ECG lead for deriving respiratory signal
PublikacjaEDR is an interesting measuring technique that allows an indirect assessment of respiratory activity. This is an alternative solution to direct methods that are based on the measurement of air flow, which require a specialized sensor or even a system. However, due to inter-personal anatomical differences, the optimal ECG lead (placement of the electrodes) ensuring the best EDR signal quality is not fixed. An influence of ECG lead...
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Application of spectroscopy to the measurement of blood parameters
PublikacjaSpectroscopy is the study of formation and interpretation of the spectra arising from the interactions of all types of radiation on matter, understood as a collection of atoms and molecules. This is a very important department of optics which gives us many opportunities to measure various parameters such as material blood parameters. Among the diseases that are associated significantly with changes in rheological properties of...
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Analysis of thoracic regional impedance changes using PCA approach
PublikacjaA multichannel impedance and one lead electrocardiographic recording system has been developed. The impedance measurement unit is built using a four-electrode technique. It consists of a sinusoidal, 40 kHz, current source and five measurement channels. Circumferential current electrodes have been located at a neck and an abdomen. Voltagemeasurement disk electrodes formed five two-electrode measurement ports. The impedance change...
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Numerical Model of the Aortic Valve Implanted Within Real Human Aorta
PublikacjaCardiovascular system diseases are the main cause of deaths in developed and developing countries. The main reasons are myocardial infarction, heart failure, stroke and valvular diseases. These are caused mainly by arteriosclerosis. The valvular diseases involve a significant burden for the health care system and their frequency is rising with the patient age. This work describes the tools and numerical models appropriate for modeling...
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LSA Is not Dead: Improving Results of Domain-Specific Information Retrieval System Using Stack Overflow Questions Tags
PublikacjaThe paper presents the approach to using tags from Stack Overflow questions as a data source in the process of building domain-specific unsupervised term embeddings. Using a huge dataset of Stack Overflow posts, our solution employs the LSA algorithm to learn latent representations of information technology terms. The paper also presents the Teamy.ai system, currently developed by Scalac company, which serves as a platform that...
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Genome-wide DNA methylation profiling of the regenerative MRL/MpJ mouse and two normal strains
PublikacjaAims We aimed to identify the pivotal differences in the DNA methylation profiles between the regeneration capable MRL/MpJ mouse and reference mouse strains. Materials and Methods Global DNA methylation profiling was performed in ear pinnae, bone marrow, spleen, liver, heart from uninjured adult females of the MRL/MpJ and C57BL/6J and BALB/c. Results and conclusion A number of differentially methylated regions distinguishing between...
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Wavelet transform analysis reveals differences between patients with impaired LVEF and healthy individuals
PublikacjaHeart failure (HF) is a global pandemic. It af- fects 64 million people worldwide, with stead- ily increasing incidence, morbidity, mortality, and economic burden [1]. Forecasts indicate continued rising prevalence, especially among the elderly and in low-to-middle socio-de- mographic index regions [2]. Left ventricular ejection fraction (LVEF) significantly impacts HF treatment and prognosis [3]. The sequence of physiological...
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Analiza niezawodności człowieka-operatora w kontekście bezpieczeństwa funkcjonalnego.
PublikacjaArtykuł przedstawia niektóre kwestie analizy warstwowego systemu zabezpieczeń instalacji podwyższonego ryzyka z uwzględnieniem analizy niezawodności człowieka HRA (human reliability analysis). Działania człowieka operatora w odniesieniu do systemu operatorskiego HSI (human system interface), w tym systemu alarmowego i potencjalnych błędów człowieka mogą mieć istotny wpływ na wyniki analiz probabilistycznych w procesie weryfikacji...
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Collaborative planning? Not yet seen in Poland. Identifying procedural gaps in the planning system 2003–2023
PublikacjaCollaborative planning aims to increase the legitimacy of decision-making in spatial development. In this approach, planning involves debate and engagement in discourse, and participation and interaction between actors are thus at the heart of the planning process. This article examines whether the planning system in Poland as defined for the period 2003–2025 provides a level of participation and deliberation and other qualities...
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A MEASUREMENT SYSTEM FOR MONITORING CARDIOVASCULAR EVENTS IN SYNCOPE PATIENTS
PublikacjaSyncope phenomena is an abrupt and transient loss of consciousness leading to interruption of awareness of one’s surroundings and falls with risk of injury. Syncope is often followed by complete and usually rapid spontaneous recovery. It is said that half of all individuals experience syncopal event at least once during their life. The condition can occur at any age and happens in people with and without other medical problems....
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Insulin-like growth factor type 2 is better than insulin-like growth factor type 1 a survival marker in patients after acute decompensation of heart failure
PublikacjaIntroduction:A decreased IGF-1 has been found in heart failure (HF). There are no reports assessing IGF-2 in HF, although in vitro study has shown, that IGF-2 stimulates cardiomyocyte proliferation more than IGF-1. The study aim was to compare the IGF-1 and IGF-2 concentration depending on HF exacerbation and annual survival.Material and methods:Among 75 patients hospitalized...
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Artificial intelligence models in prediction of response to cardiac resynchronization therapy: a systematic review
PublikacjaThe aim of the presented review is to summarize the literature data on the accuracy and clinical applicability of artificial intelligence (AI) models as a valuable alternative to the current guidelines in predicting cardiac resynchronization therapy (CRT) response and phenotyping of patients eligible for CRT implantation. This systematic review was performed...
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A semiempirical model for low energy electron–atom transport cross sections: The case of noble gases
PublikacjaA semiempirical approach to describe low energy electron–atom transport cross sections of easy implementation and reproduction is presented. The heart of the model is an energy independent two-parameter potential that was adjusted to reproduce the accurate total cross sections for He, Ne, Ar and Kr, measured with a threshold photoelectron source technique from meV up to 20 eV. Once the potential was conceived, the model was validated...
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Tools for Automatic Wound Healing Evaluation
PublikacjaFinal results of the research project devoted to development of a new objective and quantitative method of post cardiosurgery wound healing diagnostics, already preliminary discussed at the QIRT 2014 Conference, is presented. We assumed that thermal processes should be effective in subtle description of temporal changes of tissue thermal properties after surgical interventions. To prove this assumption more than 400 patients after...
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Revitalizing the Sacral Complex of the Parish of the Sacred Heart of Jesus in Gdynia: A Comprehensive Restoration Project in Alignment with Monument Conservator's Guidelines and Technical Prerequisites
PublikacjaReligiouscomplexes, due to their monumental character, belong to the group of facilities in which carrying out renovation works is difficult. Very often, construction works carried out as part of planned renovation work include not only modernization but also repair works, includingthose related to the reinforcement of structural elements. Renovation work in sacral buildings is particularly difficult when they...
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Epigenetic regulation and regeneration: the search for differentially methylated genes in the MRL mouse
PublikacjaThe MRL mouse is an inbred laboratory strain, which was developed in the 60’s of the 20th century and has been extensively used as a model of lupus erythematosus. The regenerative abilities of the strain were discovered in the 90' when the MRL mouse was shown to close 2 mm hole punches made in the ear pinnae four weeks after injury without scarring. The phenomenon has not been observed in other mouse strains, where the holes...
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Arterial cannula shape optimization by means of the rotational firefly algorithm
PublikacjaThe article presents global optimization results of arterial cannula shapes by means of the newly modified firefly algorithm. The search for the optimal arterial cannula shape is necessary in order to minimize losses and prepare the flow that leaves the circulatory support system of a ventricle (i.e. blood pump) before it reaches the heart. A modification of the standard firefly algorithm, the so-called rotational firefly algorithm,...
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Application of 3D- printed hydrogels in wound healing and regenerative medicine
PublikacjaHydrogels are three-dimensional polymer networks with hydrophilic properties. The modifiable properties of hydrogels and the structure resembling living tissue allow their versatile application. Therefore, increasing attention is focused on the use of hydrogels as bioinks for three-dimensional (3D) printing in tissue engineering. Bioprinting involves the fabrication of complex structures from several types of materials, cells,...
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An IoT-Based Computational Framework for Healthcare Monitoring in Mobile Environments
PublikacjaThe new Internet of Things paradigm allows for small devices with sensing, processing and communication capabilities to be designed, which enable the development of sensors, embedded devices and other ‘things’ ready to understand the environment. In this paper, a distributed framework based on the internet of things paradigm is proposed for monitoring human biomedical signals in activities involving physical exertion. The main...
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Special techniques and future perspectives: Simultaneous macro- and micro-electrode recordings
PublikacjaThere are many approaches to studying the inner workings of the brain and its highly interconnected circuits. One can look at the global activity in different brain structures using non-invasive technologies like positron emission tomography (PET) or functional magnetic resonance imaging (fMRI), which measure physiological changes, e.g. in the glucose uptake or blood flow. These can be very effectively used to localize active patches...
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APPLICATION OF STATISTICAL FEATURES AND MULTILAYER NEURAL NETWORK TO AUTOMATIC DIAGNOSIS OF ARRHYTHMIA BY ECG SIGNALS
PublikacjaAbnormal electrical activity of heart can produce a cardiac arrhythmia. The electrocardiogram (ECG) is a non-invasive technique which is used as a diagnostic tool for cardiac diseases. Non-stationarity and irregu- larity of heartbeat signal imposes many difficulties to clinicians (e.g., in the case of myocardial infarction arrhythmia). Fortunately, signal processing algorithms can expose hidden information within ECG signal contaminated...
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Non-Contact Monitoring of ECG in the Home Environment—Selecting Optimal Electrode Configuration
PublikacjaCapacitive electrocardiography (cECG) is most often used in wearable or embedded measurement systems. The latter is considered in the paper. An optimal electrocardiographic lead, as an individual feature, was determined based on model studies. It was defined as the possibly highest value of the R-wave amplitude measured on the back of the examined person. The lead configuration was also analyzed in terms of minimizing its susceptibility...
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Bound on Bell inequalities by fraction of determinism and reverse triangle inequality
PublikacjaIt is an established fact that entanglement is a resource. Sharing an entangled state leads to nonlocal correlations and to violations of Bell inequalities. Such nonlocal correlations illustrate the advantage of quantum resources over classical resources. In this paper, we quantitatively study Bell inequalities with 2 × n inputs. As found in Gisin et al. [Int. J. Quantum. Inform. 05, 525 (2007)], quantum mechanical correlations...
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Simulation of fluid structure interaction in a novel design of high pressure axial piston hydraulic pump
PublikacjaA novel type of an axial, piston-driven high pressure hydraulic pump with variable capacity marks a significant improvement in the area of the hydraulic machinery design. Total discharge from hydrostatic forces eliminates a need for a servomechanism, thus simplifying operation, reducing weight and introducing the possibility of the pump displacement control by computer. PWK-type pumps, invented in the Gdansk University of Technology,...
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Simulation of fluid structure interaction in a novel design of high pressure axial piston pump
PublikacjaA novel type of an axial, piston-driven high pressure hydraulic pump with variable capacity marks a significant improvement in the area of the hydraulic machinery design. Total discharge from hydrostatic forces eliminates a need for a servomechanism, thus simplifying operation, reducing weight and introducing the possibility of the pump displacement control by computer. PWK-type pumps, invented in the Gdansk University of Technology,...
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New Polymeric Materials for Solid Phase Extraction
PublikacjaSolid phase extraction (SPE) is a popular sample preparation technique, which can be applied directly in gas–solid phase and liquid–solid phase, or indirectly to solid samples by using, e.g., thermodesorption with subsequent chromatographic analysis. Although SPE can be described as a physical extraction process involving a liquid phase and a solid phase, the increased use of packed sorbent formats seems to have led to a bias toward...
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Bioactivities of Phenolic Compounds from Kiwifruit and Persimmon
PublikacjaFruit used in the common human diet in general, and kiwifruit and persimmon particularly, displays health properties in the prevention of heart disease. This study describes a combination of bioactivity, multivariate data analyses and fluorescence measurements for the differentiating of kiwifruit and persimmon, their quenching and antioxidant properties. The metabolic differences are shown, as well in the results of bioactivities...
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Epigenetic Basis of Regeneration: Analysis of Genomic DNA Methylation Profiles in the MRL/MpJ Mouse
PublikacjaEpigenetic regulation plays essential role in cell differentiation and dedifferentiation, which are the intrinsic processes involved in regeneration. To investigate the epigenetic basis of regeneration capacity, we choose DNA methylation as one of the most important epigenetic mechanisms and the MRL/MpJ mouse as a model of mammalian regeneration known to exhibit enhanced regeneration response in different organs. We report the...
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Quantifying inconsistencies in the Hamburg Sign Language Notation System
PublikacjaThe advent of machine learning (ML) has significantly advanced the recognition and translation of sign languages, bridging communication gaps for hearing-impaired communities. At the heart of these technologies is data labeling, crucial for training ML algorithms on a huge amount of consistently labeled data to achieve models that generalize well. The adoption of language-agnostic annotations is essential to connect different sign...
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The protocol for using elastic wall model in modeling blood flow within human artery
PublikacjaMedical diagnostic tools will play a major role in the future for an effective patient treatment and reduction their mortality, related to the cardiovascular system diseases (CVDs). There is an urgent need for developing diagnostic procedure to be robust, reliable, accurate and efficient, in the framework of a paradigm shift. Application of numerical techniques is seen as a perspective tool for such purpose. Nevertheless, existing...
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The Effectiveness of Basic Resuscitation Activities Carried out by Combat Paramedics of the Police, as Exemplified by Polish Counterterrorist Units
PublikacjaThe tasks carried out by Police officers are often accompanied by dangerous situations that threaten the life and health of the people involved, the police themselves, and bystanders. It concerns especially counter-terrorism police units whose activities are aimed at terrorists and particularly dangerous criminals, and their course is violent and aggressive. In conjunction with the inability to bring civilian rescue services into...
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The energy concept of money
PublikacjaPurpose: This paper aims to provide the literature review seeking an answer whether energy can be used as a universal equivalent instead of money. Methodology: The author conducted a review of available literature and data sources related to the money theory and energy concept of money. Findings: It was found that the definition of energy as a general equivalent has a contextual and dynamic nature, and this field’s consolidation...
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Transcriptome profiling reveals distinctive traits of retinol metabolism and neonatal parallels in the MRL/MpJ mouse
PublikacjaBackground: The MRL/MpJ mouse is a laboratory inbred strain known for regenerative abilities which are manifested by scarless closure of ear pinna punch holes. Enhanced healing responses have been reported in other organs. A remarkable feature of the strain is that the adult MRL/MpJ mouse retains several embryonic biochemical characteristics, including increased expression of stem cell markers. Results: We explored the transcriptome...
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Battery Technologies in Electric Vehicles: Improvements in Electric Battery Packs
PublikacjaRestrictions on fossil fuels and related environmental pollution issues motivate many organizations and countries to set their focus on electric vehicles (EVs) rather than conventional internal combustion engine vehicles [1], [2]. EVs require an energy storage system to store converted electric power in another form of energy and then reconvert the stored energy to electric power whenever it is required. The energy stored can be...
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Higher responsiveness to rosuvastatin in polygenic versus monogenic hypercholesterolaemia: a propensity score analysis
PublikacjaBackground The underlying monogenic defect in familial hypercholesterolemia (FH) can be detected in ∼40% of cases. The majority of mutation-negative patients have a polygenic cause of high LDL-cholesterol (LDL-C) due to having inherited a greater than average number of common LDL-C raising single nucleotide polymorphisms (SNPs). Purpose We sought to investigate, whether the monogenic or polygenic defect in FH is associated with...
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Machine Learning and Deep Learning Methods for Fast and Accurate Assessment of Transthoracic Echocardiogram Image Quality
PublikacjaHigh-quality echocardiogram images are the cornerstone of accurate and reliable measurements of the heart. Therefore, this study aimed to develop, validate and compare machine learning and deep learning algorithms for accurate and automated assessment of transthoracic echocardiogram image quality. In total, 4090 single-frame two-dimensional transthoracic echocardiogram...
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Design Methodology for Small Passenger Ships On the Example of the Ferryboat Motława 2 Driven by Hybrid Propulsion System
PublikacjaDynamic development in practically all elds of science and engineering has not passed over shipbuilding . In last years , engineers got to their use computer soware which makes it possible to perform strength and hydrodynamic calculations as well as to visualize design projects in 3 D space [1-4]. At their disposal they have full spectrum of modern solutions associated with the use of advanced materials and technologies [5-7]....
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Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a dimericcRGD Peptide for Targeted Imaging of αVβ3 Integrin Activity
PublikacjaCyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α V β3 integrin. We report the synthesis, chemical characterization, and biological evaluation of two novel dimeric cyclic RGD-based molecular probes for the targeted imaging of α V β3 activity (a radiolabeled version, 64Cu-NOTA-PEG4-cRGD2, for PET imaging, and a fluorescent version, FITC-PEG4-cRGD2, for in...
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The potential role of bisphenol A in the pathogenesis of polycystic ovary syndrome
PublikacjaPolycystic ovary syndrome (PCOS) is the most common endocrinopathy in women of reproductive age, that lead to infertility, type 2 diabetes and coronary heart disease. Bisphenol A (BPA) is one of the most abundant chemicals produced worldwide and is used as a plasticizer in daily life. Nowadays it is also well know that it can interact with estrogen receptors, androgen receptors and peroxisome proliferatoractivated receptors g (PPARg)....