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Wyniki wyszukiwania dla: terminal
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Specific Binding of Cholesterol to the Amyloid Precursor Protein: Structure of the Complex and Driving Forces Characterized in Molecular Detail
PublikacjaC99 is the C-terminal membrane-bound fragment of the amyloid precursor protein that is cleaved by γ-secretase to release Aβ peptides, the hallmark of Alzheimer’s disease (AD). Specific interactions of C99 with cholesterol have been proposed to underlie the recognized role of cholesterol in promoting amyloidogenesis. By using molecular dynamics simulations, we studied cholesterol binding to C99 in a lipid bilayer. We determined...
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Opinia dotycząca zasadności wykonanych robót hydrotechnicznych i sposobu zagospodarowania nieruchomości w kontekście wykorzystania jako morski port przeładunkowy.
PublikacjaOpinię przygotowano na podstawie umowy zawartej w Gdyni w dniu 2 lutego 2023r. pomiędzy Gdynia Container Terminal Sp. z o.o. z siedzibą w Gdyni przy ul. Energetyków 5 oraz Politechniką Gdańską z siedzibą w Gdańsku ul. Narutowicza 11/12.
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Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their in silico assessment as potential ligands for N-protein of SARS-CoV-2
PublikacjaIn view of recent global pandemic the 3-alkynyl substituted 2-chloroquinoxaline framework has been explored as a potential template for the design of molecules targeting COVID-19. Initial in silico studies of representative compounds to assess their binding affinities via docking into the N-terminal RNA-binding domain (NTD) of N-protein of SARS-CoV-2 prompted further study of these molecules. Thus building of a small library of...
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International trade and containerization - certain trends after the financial crisis of 2007-2008
PublikacjaThe following article presents the situation on international trade and the global maritime container transport market after the financial crisis of 2007-2008. In the first part the author focuses on describing the specifics of containerization in global trade. The following parts include characteristic of container terminal operators and shipping lines. Finally, significant changes in the global container handling market after...
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In silico assessment and sonochemical synthesis of 2-alkynyl 3-chloropyrazines as prospective ligands for SARS-CoV-2
PublikacjaThe recent global pandemic caused by COVID-19 has triggered an intense effort worldwide towards the development of an effective cure for this disease. In our effort we have explored the 2-alkynyl substituted 3-chloropyrazine framework as a potential template for the design of molecules for this purpose. Our strategy was supported by the in silico studies of representative compounds to assess their binding affinities via docking...
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Congestive heart failure - Female, 53 - Tissue image [12060630017635011]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Congestive heart failure - Female, 53 - Tissue image [1206063001763251]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Calculations of Short-Circuit Current Flows in Earth Wires of HV Lines
PublikacjaThis paper presents a method which enables calculating flows of short-circuit currents in earth wires of high voltage transmission lines, and its implementation in the form of a computer programme. The algorithm enables performing calculations for a double-fed line and starconnected lines (three terminal lines). The developed programme enables verifying dimensioning of earth wires in the context of their short-circuit thermal withstand...
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Statistical Tuning of Walfisch-Ikegami Model for the Untypical Environment
PublikacjaThe Walfisch-Ikegami model has been investigated in terms of mobile radio systems designing in the untypical environment such as the maritime container terminal. The measurement equipment and procedures have been described as well as characteristics of investigated environment. Results of the statistical tuning in terms of path loss estimation in such environment have been analysed. The analysis has proved improvement of the path...
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Statistical Tuning of Walfisch-Ikegami Model for the Untypical Environment
PublikacjaThe Walfisch-Ikegami model has been investigated in terms of mobile radio systems designing in the untypical environment such as the maritime container terminal. The measurement equipment and procedures have been described as well as characteristics of investigated environment. Results of the statistical tuning in terms of path loss estimation in such environment have been analysed. The analysis has proved improvement of the path...
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A compact smart sensor based on a neural classifier for objects modeled by Beaunier's model
PublikacjaA new solution of a smart microcontroller sensor based on a simple direct sensor-microcontroller interface for technical objects modeled by two-terminal networks and by the Beaunier’s model of anticorrosion coating is proposed. The tested object is stimulated by a square pulse and its time voltage response is sampled four times by the internal ADC of microcontroller. A neural classifier based on measurement data classifies the...
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Pulmonary oedema - Female, 60 - Tissue image [10080730015786461]
Dane BadawczeThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Pulmonary oedema - Female, 60 - Tissue image [10080730015782421]
Dane BadawczeThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Pulmonary oedema - Female, 60 - Tissue image [10080730015785181]
Dane BadawczeThis is the histopathological image of BRONCHUS AND LUNG tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other diseases of liver - Female, 60 - Tissue image [10080730015787591]
Dane BadawczeThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Suppressors of lapC mutation identify new regulators of LpxC, which mediates the first committed step in lipopolysaccharide biosynthesis
PublikacjaGram-negative bacteria, such as Escherichia coli, are characterized by an asymmetric outer membrane (OM) with lipopolysaccharide (LPS) located in the outer leaflet and phospholipids facing the inner leaflet. E. coli recruits LPS assembly proteins LapB, LapC and LapD in concert with FtsH protease to ensure a balanced biosynthesis of LPS and phospholipids. We recently reported that bacteria either lacking the periplasmic domain of...
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Karolina Zielińska-Dąbkowska dr inż. arch.
OsobyKarolina M. Zielinska-Dabkowska (dr inż. arch., Dipl.-Ing. Arch.[FH]) jest adiunktem na Wydziale Architektury Politechniki Gdańskiej. W roku 2002 ukończyła studia na Wydziale Architektury i Urbanistyki Politechniki Gdańskiej a w 2004 inżynierii architektonicznej na HAWK Hochschule für angewandte Wissenschaft und Kunst Hildesheim w Niemczech. Po studiach pracowała dla kilku firm o światowej renomie w Berlinie, Londynie, Nowym Jorku...
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Naprawa przegubów Estakady Kwiatkowskiego w Gdyni = Hinges repair og the E. Kwiatkowskiego trestle bridge in Gdynia
PublikacjaE. Kwiatkowskiego trestle bridge is one of the main parts of road infrastructure that connects sea transport (container terminal BTC) national roads A1,1,7. Every limitation of motor traffic causes many problems for Gdynia inhabitants and moreover economical loss in transport economy. In recent two years there were expertise and repair project of hinges carried out. Paper presents genesis and reasons of hinges damages, theoretical...
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Detection of the First Component of the Received LTE Signal in the OTDoA Method
PublikacjaIn a modern world there is a growing demand for localization services of various kinds. Position estimation can be realized via cellular networks, especially in the currently widely deployed LTE (Long Term Evolution) networks. However, it is not an easy task in harsh propagation conditions which often occur in dense urban environments. Recently, time-methods of terminal localization within the network have been the focus of attention,...
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Modelowanie dokładności radiolokalizowania w różnych warunkach środowiskowych przy wykorzystaniu interfejsu radiowego 5G-NR
PublikacjaW artykule przedstawiono wyniki eksperymentalnych badań dokładności estymacji położenia terminala użytkownika korzystającego~z interfejsu radiowego 5G-NR. W środowisku miejskim dokonano rejestracji rzeczywistych sygnałów sieci 5G, a następnie przeprowadzono badania numeryczne. Celem było zweryfikowanie różnic dokładności estymacji położenia w trzech różnych środowiskach: wewnątrz- i zewnątrzbudynkowym oraz tzw. deep-indoor.
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Cerebral oedema - Male, 71 - Tissue image [12030630017646831]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified disorders of brain - Female, 60 - Tissue image [10080730015788881]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Cerebral oedema - Male, 71 - Tissue image [12030630017648691]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified disorders of brain - Female, 60 - Tissue image [1008073001578411]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified disorders of brain - Female, 60 - Tissue image [10080730015783191]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Acute renal failure with tubular necrosis - Female, 60 - Tissue image [10080730015788841]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified disorders of brain - Female, 60 - Tissue image [10080730015786641]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Cerebral oedema - Male, 71 - Tissue image [12030630017648261]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Other specified disorders of brain - Female, 60 - Tissue image [10080730015785391]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Stages of development of payment cards in Poland
Dane BadawczeAn important stage in the development of the Polish card market was the commencement of the card and check center of Bank Pekao SA in 1992, which became a professional technical background for the widespread issuance of bank cards. At the same year PolCard SA, became the first agent in the country, launched its own terminals for payment intermediation...
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Cerebral oedema - Male, 71 - Tissue image [12030630017641381]
Dane BadawczeThis is the histopathological image of BRAIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Szybkie szacowanie zasięgu stacji bazowej standardu IEEE 802.16-2004
PublikacjaW pracy przedstawiono procedurę szacowania zasięgu stacji bazowej standardu IEEE 802.16-2004. Procedura polega na wykonywaniu serii pomiarów cišgłych po ustalonej trasie tworzacej siatkę. Dzięki temu możliwa jest aproksymacja obszaru, w którym system zapewnia łšcznoć. Do pomiarów wykorzystywany jest wyłšcznie standardowy sprzęt kliencki (terminal). Praca zawiera również omówienie problematyki wykonywania takich pomiarów oraz odpowiedniej...
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Path Loss Modelling in the Untypical Outdoor Propagation Environments
PublikacjaIn the paper three ways of path loss modelling in the untypical outdoor environments are presented. The exemplary untypical outdoor environment is analyzed. The investigated environment is characterized, and the measurement campaign are shortly described. The following models have been analyzed: the COST231 Walfisch-Ikegami model, the modified COST231Walfisch-Ikegami model tuned on the basis of empirical data, and the empirical...
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Realizacja usługi Fax w sieci z technologią IP
PublikacjaZastosowanie technologii IP jako platformy usług telekomunikacyjnych wymaga realizacji przez tą sieć usługi Fax. Niestety specyfika tej usługi oraz właściwości sieci z protokołem IP stwarzają szereg problemów przy praktycznej jej realizacji. W niniejszym artykule przedstawiono dwa sposoby realizacji usługi Fax w postaci aplikacji SIP-t31modem oraz Terminal-T.38. Oba rozwiązania poddano testom i omówiono uzyskane wyniki.
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Conservation and diversity of MutS proteins
PublikacjaThe homologues of MutS, mismatch repair protein, exist in all prokaryotes, with the exception of Actinobacteria, Mollicutes and part of the Archaea. Multiple alignments of 316 MutS amino acid sequences from 169 species revealed conserved residues and sequence motifs distinguishing MutS homologues. All MutS homologues show high conservation within the ATPase domain. MutS1, the homologue responsible for DNA mismatch recognition,...
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Extracting functional groups of ALLINI to design derivatives of FDA‐approved drugs: Inhibition of HIV‐1 integrase
PublikacjaHIV‐1 integrase (IN) is crucial for integration of viral DNA into the host genome and a promising target in development of antiretroviral inhibitors. In this work, six new compounds were designed by linking the structures of two different class of HIV‐1 IN inhibitors (active site binders and allosteric IN inhibitors (ALLINIs)). Among newly designed compounds, INRAT10b was found most potent HIV‐1 IN inhibitor considering different...
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Structural features responsible for control of the eukaryotic GlcN-6-P synthase activity
PublikacjaGlucosamine-6-phosphate (GlcN-6-P) synthase is responsible for catalysis of the first and practically irreversible step in hexosamine metabolism. As UDP-GlcNAc, the final product of the hexosamine path, constitutes one of the essential substrates for assembly of bacterial and fungal cell walls, the enzyme is an interesting target for antimicrobial therapy.The structure of E. coli enzyme, known since 2001, forms a dimer of two identical...
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Power Hardware-in-the-Loop Approach In Power System Development
PublikacjaThe main objective of the research is the verification of the Power Hardware-In-The-Loop (PHIL) approach in power system analysis and design. The premise of the article is that using PHIL approach the performance of the power system in steady and transient state conditions can be analysed in real power system conditions. Models of induction machine were developed and real time simulations were performed. Simulation variables were...
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A quasi-2D small-signal MOSFET model - main results
PublikacjaDynamic properties of the MOS transistor under small-signal excitation are determined by kinetic parameters of the carriers injected into the channel, i.e., the low-field mobility, velocity saturation, mobility at the quiescent-point (Q-point), longitudinal electric field in the channel, by dynamic properties of the channel, as well as by an electrical coupling between the perturbed carrier concentration in the channel and the...
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BADANIE JAKOŚCI TRANSMISJI W KANALE RADIOWYM Z PROPAGACJĄ WIELODROGOWĄ DLA INTERFEJSU RADIOWEGO MC-CDMA
PublikacjaW referacie zostały zaprezentowane wyniki badań symulacyjnych jakości transmisji w interfejsie radiowym MC-CDMA dla transmisji w kanale z propagacją wielodrogową. Symulacje zostały przeprowadzone w środowisku miejskim okołobudynkowym dla użytkowników pieszych i w pojazdach (ang. Outdoor to Indoor and Pedestrian Environment). Środowisko to charakteryzuje się małymi mocami nadajników i małymi promieniami komórek. W symulacjach terminal...
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ASYNCHRONICZNA METODA TDOA
PublikacjaPrzedstawiono nową metodę lokalizowania terminali ruchomych MT (Mobile Terminal) w sieciach radiowych, w których stacje bazowe BS (Base Station) pracują asynchronicznie względem siebie. Metoda ta, nazwana ATDOA (Asynchronous Time Difference of Arrival), umożliwia estymację położenia MT na podstawie pomiarów różnicy czasów propagacji sygnałów radiowych pomiędzy terminalem ruchomym będącym w ruchu, a pojedynczą stacją bazową w różnych...
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Homoleptic mono-, di-, and tetra-iron complexes featuring phosphido ligands: a synthetic, structural, and spectroscopic study
PublikacjaWe report the first series of homoleptic phosphido iron complexes synthesized by treating either the β-diketiminato complex [(Dippnacnac)FeCl2Li(dme)2] (Dippnacnac = HC[(CMe)N(C6H3-2,6-iPr2)]2) or [FeBr2(thf )2] with an excess of phosphides R2PLi (R = tBu, tBuPh, Cy, iPr). Reaction outcomes depend strongly on the bulkiness of the phosphido ligands. The use of tBu2PLi precursor led to an anionic diiron complex 1 encompassing a planar...
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Cloning, expression, and biochemical characterization of a coldactive GDSL-esterase of a Pseudomonas sp. S9 isolated from Spitsbergen island soil
PublikacjaAn estS9 gene, encoding an esterase of the psychrotolerant bacterium Pseudomonas sp. S9 was cloned and sequenced. The deduced sequence revealed a protein of 636 amino acid residues with a molecular mass of 69 kDa.Further amino acid sequence analysis revealed that the EstS9 enzyme contained a G-D-S-L motif centered at a catalytic serine, an N-terminal catalytic domain and a C-terminal autotransporter domain. Two recombinant E. coli...
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The Influence of Limiters UEL and OEL (The power angle, stator's current and excitation current) ot the possibility of voltage collapse development
PublikacjaVoltage stability has been a major concern for power system utilities because of event of voltage collapses in the recent past. Sometimes, power system events have shown the need for generators to operate in the overexcited and underexcited region to support stable operation. Modern excitation systems include devices for controlling or limiting machine terminal voltage (overvoltage limiters), volts per hertz ratio (V/Hz limiters),...
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Visual Detection of People Movement Rules Violation in Crowded Indoor Scenes
PublikacjaThe paper presents a camera-independent framework for detecting violations of two typical people movement rules that are in force in many public transit terminals: moving in the wrong direction or across designated lanes. Low-level image processing is based on object detection with Gaussian Mixture Models and employs Kalman filters with conflict resolving extensions for the object tracking. In order to allow an effective event...
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Characterization of CaTi0.9Fe0.1O3/La0.98Mg0.02NbO4 composite
PublikacjaA composite of CaTi0.9Fe0.1O3 and electrolyte material, i.e. magnesium doped La0.98Mg0.02NbO4 was prepared and studied. The phase content and the sample microstructure was examined by an X-ray diffraction method and scanning electron microscopy. EDS measurements were done both for composite samples and the diffusion couple. The electrical properties were studied by four terminal DC method. The Ahigh-temperature interaction between...
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Optimization of Hydrogen - Evolving Photochemical Molecular Devices
PublikacjaA molecular photocatalyst consisting of a RuII photocenter, a tetrapyridophenazine bridging ligand, and a PtX2 (X=Cl or I) moiety as the catalytic center functions as a stable system for light-driven hydrogen production. The catalytic activity of this photochemical molecular device (PMD) is significantly enhanced by exchanging the terminal chlorides at the Pt center for iodide ligands. Ultrafast transient absorption spectroscopy...
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Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70
PublikacjaThe J-domain protein Zuotin is a multi-domain eukaryotic Hsp70 co-chaperone. Though it is primarily ribosome-associated, positioned at the exit of the 60S subunit tunnel where it promotes folding of nascent polypeptide chains, Zuotin also has off-ribosome functions. Domains of Zuotin needed for 60S association and interaction with Hsp70 are conserved in eukaryotes. However, whether the 4-helix bundle (4HB) domain is conserved remains...
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Dworzec kolejowy w strukturze miasta : nowe szanse
PublikacjaRenesans kolei nie dotyczy całej sieci, ale jedynie nowych linii, będących w rzeczywistości nową formą szybkiego transportu pasażerskiego, konkurencyjnego dla regionalnych linii lotniczych. Nowe formy przestrzenne dworców kolejowych III generacji wymagają nowatorskiego podejścia do projektowania. Głównymi czynnikami projektowania węzłów komunikacyjnych winno być koordynowanie i organizacja ruchu pasażerów i pojazdów. Architektura...
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Selection of excitation signals for high-impedance spectroscopy
PublikacjaA method of fast impedance spectroscopy of technical objects with high impedance (|Zx| > 1 GOhm) is evaluated in this paper. An object is excited with a signal generated by a digital-to-analog converter (DAC) located on the U2531A DAQ module. Response signals proportional to current flowing through and voltage across the measured object are sampled by analog-to-digital converters (ADC) in the DAQ module. The object impedance spectrum...