Wyniki wyszukiwania dla: biophotonics - MOST Wiedzy

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Wyniki wyszukiwania dla: biophotonics

Wyniki wyszukiwania dla: biophotonics

  • Journal of Biophotonics

    Czasopisma
    SHERPA RoMEO Biały Pomoc

    ISSN: 1864-063X

  • Label‐free optical detection of cyclosporine in biological fluids

    Publikacja

    - Journal of Biophotonics - 2018

    In this paper, a spectroscopic method for determination of cyclosporine concentrations in biological fluids is presented. Blood plasma and hemoglobin solutions are chosen for the experiment. For various cyclosporine concentrations in blood plasma and hemoglobin, absorbance measurements in spectra range from 600 to 1100 nm are performed. The measurement results are analyzed by the use of a dedicated algorithm. The obtained data...

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  • Full scattering profile of circular optical phantoms mimicking biological tissue

    Publikacja

    - 2017

    Human tissue is one of the most complex optical media since it is turbid and nonhomogeneous. In our poster, we suggest a new type of skin phantom and an optical method for sensing physiological tissue condition, basing on the collection of the ejected light at all exit angles, to receive the full scattering profile. Conducted experiments were carried out on an unique set-up for noninvasive encircled measurement. Set-up consisted...

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  • Prototype of an opto-capacitive probe for non-invasive sensing cerebrospinal fluid circulation

    Publikacja

    - 2017

    In brain studies, the function of the cerebrospinal fluid (CSF) awakes growing interest, particularly related to studies of the glymphatic system in the brain, which is connected with the complex system of lymphatic vessels responsible for cleaning the tissues. The CSF is a clear, colourless liquid including water (H2O) approximately with a concentration of 99 %. In addition, it contains electrolytes, amino acids, glucose, and...

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  • Detection of debonding in adhesive joints using Lamb wave propagation

    Adhesively bonded joints are widely used in many branches of industry. Mechanical degradation of this type of connections does not have significant symptoms that can be noticed during visual assessment, so non-destructive testing becomes a very important issue. The paper deals with experimental investigations of adhesively bonded steel plates with different defects. Five samples (an intact one and four with damages in the form...

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  • Damage Imaging in Lamb Wave-Based Inspection of Adhesive Joints

    Adhesive bonding has become increasingly important in many industries. Non-destructive inspection of adhesive joints is essential for the condition assessment and maintenance of a structure containing such joints. The aim of this paper was the experimental investigation of the damage identification of a single lap adhesive joint of metal plate-like structures. Nine joints with different defects in the form of partial debonding...

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  • Daria Majchrowicz dr inż.

    Daria Majchrowicz w 2015 roku z wyróżnieniem uzyskała stopień magistra inżyniera na Wydziale Elektroniki, Telekomunikacji i Informatyki Politechniki Gdańskiej.  Tytuł doktora nauk technicznych otrzymała z wyróżnieniem na Politechnice Gdańskiej w 2019 roku. Jej zainteresowania naukowe skupiają się na niskokoherencyjnych czujnikach światłowodowych wykorzystujących cienkowarstwowe struktury nanodiamentowe. Pracowała w projektach badawczych...

  • Niskokoherencyjne czujniki światłowodowe przeznaczone do pracy w warunkach zmieniającego się tłumienia sygnału w torze optycznym

    Publikacja

    - 2018

    Rozprawa poświęcona jest zagadnieniu niskokoherencyjnych czujników światłowodowych. Badania przedstawione w pracy miały na celu ocenę możliwości zaimplementowania niskokoherencyjnych czujników światłowodowych do pomiaru różnych wielkości fizycznych z uwzględnieniem warunków zmieniającego się tłumienia sygnału w torze optycznym. W rozprawie zawarto informacje na temat czujników światłowodowych. Dokonano również analizy stanu wiedzy...

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  • Sensing of anesthetic drugs in blood with Raman spectroscopy

    Publikacja

    - 2015

    A proof-of-concept study of a Raman spectroscopy-based approach for measuring the content of anesthesia drugs in blood is presented. Spectra of spiked blood from several patients exhibit prominent changes in regions associated with the drug.

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  • Noise in biological Raman spectroscopy

    Publikacja

    - 2015

    Raman spectroscopy is a widely used method to investigate chemical molecules by analyzing their vibrational transitions. It utilizes inelastic scattering of the laser light irradiating the investigated object. The scattered light requires appropriate filtering to reduce dominant laser light and expose much weaker components having shifted wavelengths of a characteristic spectral pattern. These components are measured by dispersing...

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  • Absorption spectroscopy setup for determination of whole human blood and blood–derived materials spectral characteristics

    Publikacja

    A dedicated absorption spectroscopy system was set up using tungsten-halogen broadband source, optical fibers, sample holder, and a commercial spectrometer with CCD array. Analysis of noise present in the setup was carried out. Data processing was applied to the absorption spectra to reduce spectral noise, and improve the quality of the spectra and to remove the baseline level. The absorption spectra were measured for whole blood...

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  • Optical properties of the chemotherapy drugs used in the central nervous system lymphoma therapy: monitoring drug delivery

    Publikacja

    - 2015

    Our aim is to optically monitor the delivery of the chemotherapy drugs for brain tumours, particularly used in the central nervous system (CNS) lymphoma therapy. In vivo monitoring would help to optimize the treatment and avoiding unnecessary medications. Moreover, it would be beneficial to be able to measure which of the multi-regimen drugs actually do penetrate and how well into the brain tissue. There exist several potential...

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  • Detection of propofol concentrations in blood by Raman spectroscopy

    Publikacja

    - 2015

    In this paper we present a proof-of-concept of a Raman spectroscopy-based approach for measuring the content of propofol, a common anesthesia drug, in whole human blood, and plasma, which is intended for use during clinical procedures. This method utilizes the Raman spectroscopy as a chemically–sensitive method for qualitative detection of the presence of a drug and a quantitative determination of its concentration. A number of...

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  • Use of optical skin phantoms for preclinical evaluation of laser efficiency for skin lesion therapy

    Publikacja

    - JOURNAL OF BIOMEDICAL OPTICS - 2015

    Skin lesions are commonly treated using laser heating. However, the introduction of new devices into clinical practice requires evaluation of their performance. This study presents the application of optical phantoms for assessment of a newly developed 975-nm pulsed diode laser system for dermatological purposes. Such phantoms closely mimic the absorption and scattering of real human skin (although not precisely in relation to...

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  • Nanoparticle-free tissue-mimicking phantoms with intrinsic scattering

    Publikacja

    - Biomedical Optics Express - 2016

    We present an alternative to the conventional approach, phantoms without scattering nanoparticles, where scattering is achieved by the material itself: spherical cavities trapped in a silicone matrix. We describe the properties and fabrication of novel optical phantoms based on a silicone elastomer polydimethylsiloxane (PDMS) and glycerol mixture. Optical properties (absorption coefficient µa, reduced scattering coefficient µs',...

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  • Optoelectronic investigation of nanodiamond interactions with human blood

    Publikacja

    - 2016

    We present optoelectronic investigation of in vitro interactions of whole human blood with different nanodiamond biomarkers. Plasmo-chemical modifications of detonation nanodiamond particles gives the possibility for controlling their surface for biological applications. Optical investigations reveal the biological activity of nanodiamonds in blood dependent on its surface termination. We compare different types of nanodiamonds:...

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  • Integration of protein tethering in a rapid and label-free SERS screening platform for drugs of abuse

    Publikacja

    - CHEMICAL COMMUNICATIONS - 2016

    Surface enhanced Raman spectroscopy (SERS) has emerged as a promising technique for the rapid and ultrasensitive detection of molecular species such as drugs of abuse in biofluids. Yet, it remains a significant challenge to create a viable screening tool for multiple drug classes, owing to the lack of affinity of certain species for the SERS substrate and to the matrix interference in complex media. Here we report a protein tethering...

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  • Haemocompatibility of Modified Nanodiamonds

    Publikacja

    - Materials - 2017

    This study reports the interactions of modified nanodiamond particles in vitro with human blood. Modifications performed on the nanodiamond particles include oxygenation with a chemical method and hydrogenation upon chemical vapor deposition (CVD) plasma treatment. Such nanodiamonds were later incubated in whole human blood for different time intervals, ranging from 5 min to 5 h. The morphology of red blood cells was assessed along...

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  • Applications of Raman spectroscopy for detection of selected substances in tissues

    Publikacja

    - 2019

    This dissertation explores the applications of Raman spectroscopy for biological tissue analysis. Basics of Raman and surface-enhanced Raman spectroscopy (SERS) are described, along with an analysis of the literature on biodetection and non-invasive blood analysis with emphasis on glucose detection. Instrumentation for Raman measurements is described. The sources of noise and interferences occurring in biological tissue measurements...

  • Computed aided system for separation and classification of the abnormal erythrocytes in human blood

    Publikacja

    - 2017

    The human peripheral blood consists of cells (red cells, white cells, and platelets) suspended in plasma. In the following research the team assessed an influence of nanodiamond particles on blood elements over various periods of time. The material used in the study consisted of samples taken from ten healthy humans of various age, different blood types and both sexes. The markings were leaded by adding to the blood unmodified...

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