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Wyniki wyszukiwania dla: JAMMER
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The Influence of Cement Type on Early Properties of Cold In-Place Recycled Mixtures
PublikacjaCold in-place recycling is a commonly used maintenance treatment in rehabilitation of low and medium volume roads in Poland. Typically, two types of binding agents are used—cement and bituminous emulsion (or foamed bitumen).Due to the harsh Polish climate with many freeze/thaw cycles and frequent occurrence of saturated conditions, the used amounts of cement are higher than those commonly used in warmer parts of Europe. While there...
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The transition from HIF-1 to HIF-2 during prolonged hypoxia results from reactivation of PHDs and HIF1A mRNA instability
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The hypoxia‐induced changes in miRNA‐mRNA in RNA ‐induced silencing complexes and HIF ‐2 induced miRNAs in human endothelial cells
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Detection of Lexical Stress Errors in Non-Native (L2) English with Data Augmentation and Attention
PublikacjaThis paper describes two novel complementary techniques that improve the detection of lexical stress errors in non-native (L2) English speech: attention-based feature extraction and data augmentation based on Neural Text-To-Speech (TTS). In a classical approach, audio features are usually extracted from fixed regions of speech such as the syllable nucleus. We propose an attention-based deep learning model that automatically de...
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Methylene bridged glycoluril dimers: synthetic methods
PublikacjaZaprezentowano syntezę pochodnych glikolurylu tworzących ściśle sprecyzowane dimeryczne struktury w roztworze wodnym. Opisano diastereoselektywną syntezę pochodnych o strukturze amfifilowej.
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Association between use of enhanced recovery after surgery protocols and postoperative complications in colorectal surgery in Europe: The EuroPOWER international observational study
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Inhibition of inflammatory response in human keratinocytes by magnetic nanoparticles functionalized with PBP10 peptide derived from the PIP2-binding site of human plasma gelsolin
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Analysis of exhaled breath for dengue disease detection by low-cost electronic nose system
PublikacjaThis paper presents a procedure and a set-up of an electronic nose system analyzing exhaled breath to detect the patients suffering from dengue – a mosquito-borne tropical disease. Low-power resistive gas sensors (MiCS-6814, TGS8100) were used to detect volatile organic compounds (VOCs) in the exhaled breath. The end-tidal phase of patients exhaled breath was collected with a BioVOCTM breath sampler. Two strategies were assessed...
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Multi-functional monodispersed SiO2-TiO2 core-shell nanostructure and TEOS in the consolidation of archaeological lime mortars surfaces
PublikacjaArchaeological traditional lime mortars are susceptible to many environmental conditions such as the impact of water (rain, humidity, groundwater, etc.), variation of temperatures' degrees, wind and/or pollution. Accordingly, this research aims to provide newly assessed multifunctional Nano-coating for the purpose of archaeological lime mortar protection. For this, the study combined physicochemical and mechanical characterizations...
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Sampling-based novel heterogeneous multi-layer stacking ensemble method for telecom customer churn prediction
PublikacjaIn recent times, customer churn has become one of the most significant issues in business-oriented sectors with telecommunication being no exception. Maintaining current customers is particularly valuable due to the high degree of rivalry among telecommunication companies and the costs of acquiring new ones. The early prediction of churned customers may help telecommunication companies to identify the causes of churn and design...
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Progress in module design for membrane distillation
PublikacjaThere have been tremendous advances in membrane distillation (MD) since the concept was introduced in 1961: new membrane designs and process configurations have emerged, and its commercial viability has been evaluated in several pilot-scale studies. However, its high energy consumption has hindered its commercialization. One of the most promising ways to overcome this obstacle is to develop more energy-efficient membrane modules....
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Inhibition of T-type calcium channel disrupts Akt signaling and promotes apoptosis in glioblastoma cells.
PublikacjaGlioblastoma multiforme (GBM) are brain tumors that are exceptionally resitant to both radio- and chemotherapy regimens and novel approaches to treatment are needed. T-type calcium channels are one type of low voltage-gated channel (LVCC) involved in embryonic cell proliferation and differentiation; however they are often over-expressed in tumors, including GBM. In this study, we found that inhibition of T-type Ca channels in GBM...
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EXTRAORDINARY RAINFALLS IN GDANSK (NORTHERN POLAND) IN THE 21ST CENTURY
PublikacjaIn the 21st century Gdansk had been affected by two rainfall events with a total precipitation amount of over 120 mm each. Rainfall parameters exceeded the regional values of the rain occurring once every 100 years. At the meteorological station of Gdansk University of Technology, July 9th 2001 was recorded 123.5 mm and July 14th 2016, 150.8 mm rainfall (within 24 hours observation period). Despite the same seasons of summer months...
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Adenylate Kinase 4—A Key Regulator of Proliferation and Metabolic Shift in Human Pulmonary Arterial Smooth Muscle Cells via Akt and HIF-1α Signaling Pathways
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Fabrication and characterizations of hybrid materials based on polyaniline, metal oxide, and graphene nano-platelets for supercapacitor electrodes
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Robust effectiveness behavior of synthesized cobalt doped Prussian blue graphene oxide ferrite against EMI shielding
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T cell Activation Is Driven by an ADP-Dependent Glukosinase Linking Enhanced Glycolysis with Mitochondrial Reactive Oxygen Species Generation
PublikacjaMitochondria-originating reactive oxygen species control T cell receptor (TCR)-induced gene expression. Here, we show that TCR-triggered activation of ADP-dependent glucokinase (ADPGK), an alternative, glycolytic enzyme typical for Archaea, mediates generation of the oxidative signal. We also show that ADPGK is localized in the endoplasmic reticulum and suggest that its active site protrudes toward the cytosol. The ADPGK-driven...
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Designing learning-skills towards industry 4.0
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Intracranial electrophysiological recordings from the human brain during memory tasks with pupillometry
PublikacjaData comprise intracranial EEG (iEEG) brain activity represented by stereo EEG (sEEG) signals, recorded from over 100 electrode channels implanted in any one patient across various brain regions. The iEEG signals were recorded in epilepsy patients (N=10) undergoing invasive monitoring and localization of seizures when they were performing a battery of four memory tasks lasting approx. 1 hour in total. Gaze tracking on the task...
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Quantum randomness protected against detection loophole attacks
PublikacjaDevice and semi-device-independent private quantum randomness generators are crucial for applications requiring private randomness. However, they are vulnerable to detection inefficiency attacks and this limits severely their usage for practical purposes. Here, we present a method for protecting semi-device-independent private quantum randomness generators in prepare-and-measure scenarios against detection inefficiency attacks....
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Synthesis of N-doped TiO2 nanoparticles with enhanced photocatalytic activity for 2,4-dichlorophenol degradation and H2 production
PublikacjaNitrogen-doped titanium dioxide (N-TiO2) nanoparticles were prepared using a modified sol-gel method. The as-prepared nanoparticles were characterized by state-of-the-art techniques for their optical, structural and morphological properties. The crystallite size, surface area and bandgap energy of reference TiO2 and N-TiO2 nanoparticles were found to be 16.1 and 10.9 nm, 83.6 and 131.8 m2 g−1 and 3.23 and 2.89 eV, respectively....
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Advancing sustainable hybrid bitumen systems: A compatibilization solution by functionalized polyolefins for enhanced crumb rubber content in bitumen
PublikacjaPolymer waste pollution has a profound effect on the environment and, consequently, on the lifestyle of hu- mankind. The massive production and disposal of cross-linked polymers clearly exemplify the challenges of recycling. Increasing efforts are being undertaken to introduce recycled polymers, especially crumb rubber (CR), into asphalt formulations. Due to the rather poor processability and phase separation associated with CR- modified...
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Assessment of the usefulness of bacterial cellulose produced by Gluconacetobacter xylinus E25 as a new biological implant
PublikacjaBionanocellulose (BNC) is a clear polymer produced by the bacterium Gluconacetobacter xylinus. In our current study, “Research on the use of bacterial nanocellulose (BNC) in regenerative medicine as a function of the biological implants in cardiac and vascular surgery”, we carried out material analysis, biochemical analysis, in vitro tests and in vivo animal model testing. In stage 1 of the project, we carried out physical and...
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Experiencing the Ocean the Paths for Urban Development of Sao Pedro do Estoril in Lisbon Metropolitan Area
PublikacjaThe areas of Cascais Municipality, one of the richest Municipalities in Portugal, located west to Lisbon, at the estuary of Tagus and the Atlantic Ocean coast is popular tourist destination. With its unique landscape it became the most attractive venue for spending vacations, for sport activities and leisure. It arose around the coastal town of Cascais, the former fishing village famous as a refuge for notables and claiming to...
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A concerted evolution of supramolecular interactions in a {cation; metal complex; π-acid; solvent} anion-π system
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Occurrence of cyanobacteria and cyanotoxin in the Southern Baltic Proper. Filamentous cyanobacteria versus single-celled picocyanobacteria
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Empirical analysis of tree-based classification models for customer churn prediction
PublikacjaCustomer churn is a vital and reoccurring problem facing most business industries, particularly the telecommunications industry. Considering the fierce competition among telecommunications firms and the high expenses of attracting and gaining new subscribers, keeping existing loyal subscribers becomes crucial. Early prediction of disgruntled subscribers can assist telecommunications firms in identifying the reasons for churn and...
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A device for measuring heat flux on a rocket skin surface
PublikacjaA novel method for measuring heat flux on a surface is presented. It is an extensive upgrade of currently known heat flux sensors used mostly in civil engineering. As the thermal environment of launchers, especially sounding rocket can have an enormous negative effect on payload, careful considerations have to be taken in the process of preparing insulation. Usually, thermal data provided by the launch vehicle manufacturer is limited...
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Direct brain stimulation modulates encoding states and memory performance in humans
PublikacjaPeople often forget information because they fail to effectively encode it. Here, we test the hypothesis that targeted electrical stimulation can modulate neural encoding states and subsequent memory outcomes. Using recordings from neurosurgical epilepsy patients with intracranially implanted electrodes, we trained multivariate classifiers to discriminate spectral activity during learning that predicted remembering from forgetting,...
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Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
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Hydrochar-nanoparticle integration for arsenic removal from wastewater: Challenges, possible solutions, and future horizon
PublikacjaArsenic (As) contamination poses a significant threat to human health, ecosystems, and agriculture, with levels ranging from 12 to 75% attributed to mine waste and stream sediments. This naturally element is abundant in Earth's crust and gets released into the environment through mining and rock processing, causing ≈363 million people to depend on As-contaminated groundwater. To combat this issue, introducing a sustainable hydrochar...
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Technological solutions for boosting hydrogen role in decarbonization strategies and net-zero goals of world shipping: Challenges and perspectives
PublikacjaFacing the problems concerning greenhouse gas (GHG) emissions from international ocean shipping has meant that the latest regulations of the International Maritime Organization, issued on 1st January 2023, have come into force, with the aim of reducing GHG emissions from maritime activities. Hydrogen has been suggested as an alternative fuel to achieve decarbonization ambitions in the near future. Although hydrogen has been investigated...
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Plasma Lipid Composition and Risk of Developing Cardiovascular Disease
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Modelling of Thyroid Peroxidase Reveals Insights into Its Enzyme Function and Autoantigenicity
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Intelligent Decision Forest Models for Customer Churn Prediction
PublikacjaCustomer churn is a critical issue impacting enterprises and organizations, particularly in the emerging and highly competitive telecommunications industry. It is important to researchers and industry analysts interested in projecting customer behavior to separate churn from non‐churn consumers. The fundamental incentive is a firm’s intent desire to keep current consumers, along with the exorbitant expense of gaining new ones....
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Recombinant Human Plasma Gelsolin Stimulates Phagocytosis while Diminishing Excessive Inflammatory Responses in Mice with Pseudomonas aeruginosa Sepsis
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Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects
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The catalytic potential of high-κ dielectrics for graphene formation
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Empirical Analysis of Forest Penalizing Attribute and Its Enhanced Variations for Android Malware Detection
PublikacjaAs a result of the rapid advancement of mobile and internet technology, a plethora of new mobile security risks has recently emerged. Many techniques have been developed to address the risks associated with Android malware. The most extensively used method for identifying Android malware is signature-based detection. The drawback of this method, however, is that it is unable to detect unknown malware. As a consequence of this problem,...
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Behavioral state classification in epileptic brain using intracranial electrophysiology
PublikacjaOBJECTIVE: Automated behavioral state classification can benefit next generation implantable epilepsy devices. In this study we explored the feasibility of automated awake (AW) and slow wave sleep (SWS) classification using wide bandwidth intracranial EEG (iEEG) in patients undergoing evaluation for epilepsy surgery. APPROACH: Data from seven patients (age [Formula: see text], 4 women) who underwent intracranial depth electrode...
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Crystal structure and initial characterization of a novel archaeal-like Holliday junction-resolving enzyme from Thermus thermophilus phage Tth15-6
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Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site
PublikacjaAn important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) host cell receptor. Therefore, to explore conserved features in spike protein dynamics and to identify potentially novel regions for drugging, we measured spike protein variability derived from 791 viral genomes and studied its properties by molecular...
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Electronic structure of intertwined kagome, honeycomb, and triangular sublattices of the intermetallics MCo2Al9 ( M = Sr, Ba)
PublikacjaIntermetallics are an important playground to stabilize a large variety of physical phenomena, arising from their complex crystal structure. The ease of their chemical tunabilty makes them suitable platforms to realize targeted electronic properties starting from the symmetries hidden in their unit cell. Here, we investigate the family of the recently discovered intermetallics MCo2Al9 (M=Sr, Ba) and we unveil their electronic structure....
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Biotransformation of abused synthetic cannabinoids, JWH-018 and JWH-073, by human cytochromes P450 and UDP-glucuronosyltransferases
PublikacjaZwiązki oznaczone symbolami JWH-018 i JWH-073 są syntetycznymi pochodnymi kanabinoidów, obecnymi w preparatach o działaniu psychoaktywnym (K2/Spice). Wcześniejsze badań wykazały, że u osób przyjmujących tzw. ''legalną marihuanę'', głównymi produktami biotransformacji obecnymi w moczu były hydroksylowe pochodne obu związków, jak również ich glukuronidy. W związku z tym celem prowadzonych badań było określenie roli poszczególnych...
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Selectivity Tuning by Natural Deep Eutectic Solvents (NADESs) for Extraction of Bioactive Compounds from Cytinus hypocistis—Studies of Antioxidative, Enzyme-Inhibitive Properties and LC-MS Profiles
PublikacjaIn the present study, the extracts of Cytinus hypocistis (L.) L using both traditional solvents (hexane, ethyl acetate, dichloromethane, ethanol, ethanol/water, and water) and natural deep eutectic solvents (NADESs) were investigated in terms of their total polyphenolic contents and antioxidant and enzyme-inhibitive properties. The extracts were found to possess total phenolic and total flavonoid contents in the ranges of 26.47–186.13...
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Surfactant replacement therapy as promising treatment for COVID-19: an updated narrative review
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Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups
PublikacjaMastocytosis is rare disease in which genetic predisposition is not fully understood. The aim of this study was to analyze associations between mastocytosis and single nucleotide polymorphisms (SNPs) by a genome-wide association study (GWAS) approach. A total of 234 patients were enrolled in our study, including 141 with cutaneous mastocytosis (CM; 78 children and 63 adults) and 93 with systemic mastocytosis (SM, all adults)....
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Safety and efficacy of lenabasum in a phase 2 randomized, placebo-controlled trial in adults with cystic fibrosis
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Challenges in coupling atmospheric electricity with biological systems
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Problemy niepewności i integracji w przetwarzaniu danych o stanie emocjonalnym użytkownika komputera
PublikacjaIstnieje wiele programów automatycznego rozpoznawania emocji z pojedynczych modalności. Wykorzystują one różnorodne modele reprezentacji emocji, a także metody przetwarzania. Obecnie wyraźnie widoczny jest trend do wykorzystania analizy wielomodalnej oraz wielokanałowej, mającej na celu poprawę skuteczności rozpoznawania emocji oraz poprawę niezawodności. W dziedzinie automatycznego rozpoznawania emocji nie określono typowego modelu...