Filtry
wszystkich: 10620
wybranych: 512
-
Katalog
Filtry wybranego katalogu
Wyniki wyszukiwania dla: adipokines, cytokines, adrenal tumors
-
Current Challenges in Targeting Tumor Desmoplasia to Improve the Efficacy of Immunotherapy
Publikacja -
Holistic Approach to the Diagnosis and Treatment of Patients with Tumor Metastases to the Spine
Publikacja -
Clinical Relevance of Circulating Tumor Cells in Prostate Cancer Management
Publikacja -
Gemcitabine Peptide-Based Conjugates and Their Application in Targeted Tumor Therapy
Publikacja -
Recent advances in 3D bioprinted tumor models for personalized medicine
PublikacjaCancerous tumors are among the most fatal diseases worldwide, claiming nearly 10 million lives in 2020. Due to their complex and dynamic nature, modeling tumors accurately is a challenging task. Current models suffer from inadequate translation between in vitro and in vivo results, primarily due to the isotropic nature of tumors and their microenvironment's relationship. To address these limitations, hydrogel-based 3D bioprinting...
-
Molecular Diagnostics of Brain Tumours by Measuring the 5-Methylcytosine Level in Their DNA
Publikacja -
Defect in Mitochondrial NADH-Dehydrogenase Genes in Canine Mast Cell Tumours
Publikacja -
Molecular differences in mitochondrial DNA genomes of dogs with malignant mammary tumours
Publikacja -
Competences of academic tutors – research among participants of the project “Masters of Didactics”
Publikacja -
A targeted mass spectrometry immunoassay to quantify osteopontin in fresh-frozen breast tumors and adjacent normal breast tissues
Publikacja -
Radiochemical Synthesis and Evaluation of Novel Radioconjugates of Neurokinin 1 Receptor Antagonist Aprepitant Dedicated for NK1R-Positive Tumors
Publikacja -
Bioactive forms of vitamin D selectively stimulate the skin analog of the hypothalamus-pituitary-adrenal axis in human epidermal keratinocytes
Publikacja -
Cadmium, arsenic, selenium and iron– Implications for tumor progression in breast cancer
Publikacja -
ColorNephroNet: Kidney tumor malignancy prediction using medical image colorization
PublikacjaRenal tumor malignancy classification is one of the crucial tasks in urology, being a primary factor included in the decision of whether to perform kidney removal surgery (nephrectomy) or not. Currently, tumor malignancy prediction is determined by the radiological diagnosis based on computed tomography (CT) images. However, it is estimated that up to 16% of nephrectomies could have been avoided because the tumor that had been...
-
Progress in targeting tumor cells by using drug-magnetic nanoparticles conjugate.
PublikacjaTo limit the cytotoxicity of anticancer drugs against healthy cells, an appropriate carrier should be synthesized to deliver the drug to the tumor tissue only. A good solution is to anchor a magnetic nanoparticle to the molecule of the drug and to use a properly directed external magnetic field. We have shown that the improved by us synthesis of the conjugate of doxorubicin with iron-oxide magnetic nanoparticles allows a substantial...
-
Naturally-derived hydrogels for 3D pancreatic tumor models: A short review
PublikacjaStatistics suggest a high proportion of mortality rate by pancreatic cancer, which is a solid tumor characterized by high heterogeneity and the presence of a complex extracellular matrix. The very low effectiveness of pancreatic cancer treatment roots in the high metastatic potential and drug resistance of this tumor. Therefore, the quest for efficient cellular models enabling precise mimicking in vivo conditions, and anticancer...
-
Foetal haemoglobin-blood cells (F-cells) as a feature of embryonic tumours (blastomas)
Publikacja -
The aberrant overexpression of vimentin is linked to a more aggressive status in tumours of the gastrointestinal tract
Publikacja -
Segmentation-Based BI-RADS ensemble classification of breast tumours in ultrasound images
PublikacjaBackground: The development of computer-aided diagnosis systems in breast cancer imaging is exponential. Since 2016, 81 papers have described the automated segmentation of breast lesions in ultrasound images using arti- ficial intelligence. However, only two papers have dealt with complex BI-RADS classifications. Purpose: This study addresses the automatic classification of breast lesions into binary classes (benign vs. ma- lignant)...
-
Expression of zinc finger transcription factors (ZNF143 and ZNF281) in serous borderline ovarian tumors and low-grade ovarian cancers
Publikacja -
Expression of selected epithelial–mesenchymal transition transcription factors in serous borderline ovarian tumors and type I ovarian cancers
Publikacja -
Coincidental Detection of Gastrointestinal Stromal Tumors During Laparoscopic Bariatric Procedures—Data and Treatment Strategy of a German Reference Center
Publikacja -
Comparison of Selected Neural Network Models Used for Automatic Liver Tumor Segmentation
PublikacjaAutomatic and accurate segmentation of liver tumors is crucial for the diagnosis and treatment of hepatocellular carcinoma or metastases. However, the task remains challenging due to imprecise boundaries and significant variations in the shape, size, and location of tumors. The present study focuses on tumor segmentation as a more critical aspect from a medical perspective, compared to liver parenchyma segmentation, which is the...
-
A label-free graphene-based impedimetric biosensor for real-time tracing of the cytokine storm in blood serum; suitable for screening COVID-19 patients
Publikacja -
Drenaż pionowy zapory ziemnej w Żurze
PublikacjaW artykule przedstawiono rozwiązania techniczne drenażu pionowego w podstawie skarpy odpowietrznej zapory ziemnej w Żurze. Zastosowano tu zespoł studni odwadniających. Przedstawiono wyniki obserwacji piezometrycznych, które wskazują na poprawę warunków wodno-gruntowych w zaporze.
-
Molecular Heterogeneity of Papillary Thyroid Cancer: Comparison of Primary Tumors and Synchronous Metastases in Regional Lymph Nodes by Mass Spectrometry Imaging
Publikacja -
The associations between serum VEGF, bFGF and endoglin levels with microvessel density and expression of proangiogenic factors in malignant and benign ovarian tumors
Publikacja -
Expression-based decision tree model reveals distinct microRNA expression pattern in pediatric neuronal and mixed neuronal-glial tumors
Publikacja -
KRAS mutation testing in borderline ovarian tumors and low-grade ovarian carcinomas with a rapid, fully integrated molecular diagnostic system
Publikacja -
Adoptive Cell Therapy—Harnessing Antigen-Specific T Cells to Target Solid Tumours
Publikacja -
Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
Publikacja -
Overcome the tumor immunotherapy resistance by combination of the HDAC6 inhibitors with antitumor Immunomodulatory agents.
Publikacja -
Total DNA methylation as a biomarker of DNA damage and tumor malignancy in intracranial meningiomas
Publikacja -
Regarding the concurrent presence of secretory carcinoma and Warthin’s tumor in the ipsilateral parotid gland
Publikacja -
Comparison of the ability to induce apoptosis by acridine derivatives in solid tumor and leukemia cells
PublikacjaW pracy wykazano różną wrażliwość komórek nowotworowych do ulegania apoptozie pod wpływem pochodnych akrydyny.
-
Use of Cytokine Mix-, Imiquimod-, and Serum-Induced Monoculture and Lipopolysaccharide- and Interferon Gamma-Treated Co-Culture to Establish In Vitro Psoriasis-like Inflammation Models
Publikacja -
Impact of ultrasounds on physicochemical characteristics of potato tubers
Publikacja -
How acidic amino acid residues facilitate DNA target site selection
PublikacjaDespite the negative charge of the DNA backbone, acidic residues (Asp/Glu) commonly participate in the base readout, with a strong preference for cytosine. In fact, in the solved DNA/protein structures, cytosine is recognized almost exclusively by Asp/Glu through a direct hydrogen bond, while at the same time, adenine, regardless of its amino group, shows no propensity for Asp/Glu. Here, we analyzed the contribution of Asp/Glu...
-
Significance of Dermoscopy in Association with Clinical Features in Differentiation of Basal Cell Carcinoma and Benign Trichoblastic Tumours
PublikacjaBackground: Although basal cell carcinoma (BCC) can, in the majority of cases, be diagnosed based on clinical and dermoscopic assessment, a potential overlap with benign adnexal skin tumours seems to exist, including trichoblastic tumours (TT). Methods: Retrospective analysis of clinical and dermoscopic features of benign TT and BCC cases was performed to develop a diagnostic algorithm with a potential utility in clinical practice....
-
MiMSeg - an algorithm for automated detection of tumor tissue on NMR apparent diffusion coefficient maps.
Publikacja -
Carbon nanotube based dielectric spectroscopy of tumor secretion; electrochemical lipidomics for cancer diagnosis
Publikacja -
Metabolomic approach for determination of urinary nucleosides as potential tumor markers using electromigration techniques
Publikacja -
Detection of circulating tumor cells by means of machine learning using Smart-Seq2 sequencing
Publikacja -
Strategies for overcoming ABC-transporters-mediated multidrug resistance (MDR) of tumor cells. Review
PublikacjaOporność wielolekowa (MDR) nowotworów jest główną przyczyną niepowodzeń w chemoterapii przeciwnowotworowej. Jest ona wynikiem nadprodukcji w komórkach opornych transporterów białkowych z nadrodziny ABC, eksportujących cytostatyk z komórki, których działanie uniemożliwia utrzymanie terapeutycznego stężenia leku. W publikacji dokonano przeglądu różnych strategii przeciwdziałania zjawisku MDR. Strategie te dotyczą zarówno kontroli...
-
Interstrand crosslinking of DNA in tumor and fibroblast cells by C-1311 (Symadex) and other imidazoacridinones
PublikacjaImidazoakrydony, w tym pochodna C-1311 znajdująca się w pierwszej fazie badań klinicznych prowadzonych przez firmę Xanthus Life Sciences, należą do grupy bardzo aktywnych związków przeciwnowotworowych zsyntetyzowanych w Katedrze Technologii Leków i Biochemii PG. Za pomocą zmodyfikowanej metody Parsons'a wykazaliśmy, że C-1311 indukuje w sposób zależny od stężenia międzyłańcuchowe wiązania sieciujące w komórkach różnych nowotworów...
-
Detection of circulating tumor cells by means of machine learning using Smart-Seq2 sequencing
PublikacjaCirculating tumor cells (CTCs) are tumor cells that separate from the solid tumor and enter the bloodstream, which can cause metastasis. Detection and enumeration of CTCs show promising potential as a predictor for prognosis in cancer patients. Furthermore, single-cells sequencing is a technique that provides genetic information from individual cells and allows to classify them precisely and reliably. Sequencing data typically...
-
Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice
Publikacja -
Drainage and capillary rise components in water balance of alluvial soils
PublikacjaPrzepływ wody przez dolny brzeg profilu glebowego stanowi ważny element wielu modeli pracy drenażu. Przeciekanie wody w głąb albo podsiąk kapilarny ku górze mierzone były metodą lizymetryczną w warunkach polowych podczas 4 lat (1972-1975). Podsiąk kapilarny wynosił 40-50% ogólnego zasilania w wodę w glebach typu Histosols, natomiast prawie zero w glebach typu Inceptisols. Pomierzone wartości pozwalaja na ocenę wymiany wody pomiedzy...
-
Folliculotropic mycosis fungoides coexisting with pancreatic neuroendocrine tumour
Publikacja -
Influence of cultivation technology on the color of raw potato tubers
Publikacja