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Research Report - University of Sydney, Department of Civil Engineering
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Expert Review of Clinical Pharmacology
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Expert Review of Anticancer Therapy
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EXPERT OPINION ON INVESTIGATIONAL DRUGS
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EXPERT OPINION ON BIOLOGICAL THERAPY
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How to meet when you forget: log-space rendezvous in arbitrary graphs
PublikacjaTwo identical (anonymous) mobile agents start from arbitrary nodes in an a priori unknown graph and move synchronously from node to node with the goal of meeting. This rendezvous problem has been thoroughly studied, both for anonymous and for labeled agents, along with another basic task, that of exploring graphs by mobile agents. The rendezvous problem is known to be not easier than graph exploration. A well-known recent result...
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Chroniques de Port-Royal
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Fast Collaborative Graph Exploration
PublikacjaWe study the following scenario of online graph exploration. A team of k agents is initially located at a distinguished vertex r of an undirected graph. At every time step, each agent can traverse an edge of the graph. All vertices have unique identifiers, and upon entering a vertex, an agent obtains the list of identifiers of all its neighbors. We ask how many time steps are required to complete exploration, i.e., to make sure...
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Fast collaborative graph exploration
PublikacjaWe study the following scenario of online graph exploration. A team of k agents is initially located at a distinguished vertex r of an undirected graph. At every time step, each agent can traverse an edge of the graph. All vertices have unique identifiers, and upon entering a vertex, an agent obtains the list of identifiers of all its neighbors. We ask how many time steps are required to complete exploration, i.e., to make sure...
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Prospective study of brentuximab vedotin in relapsed/refractory Hodgkin lymphoma patients who are not suitable for stem cell transplant or multi-agent chemotherapy
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CYP3A4 overexpression enhances apoptosis induced by anticancer agent imidazoacridinone C-1311, but does not change the metabolism of C-1311 in CHO cells
PublikacjaWe examine whether CYP3A4 overexpression influences the rate and pattern of antitumor imidazoacridinone C-1311 metabolism, in relation to the impact of this overexpression on cell cycle progression and final cellular response of CHO cells following C-1311 treatment. Methods: Three CHO cell lines: CHO-WT, wild type, CHO-HR, overexpressing cytochrome P450 reductase (CPR) and CHO-HR-3A4, coexpressing CPR and CYP3A4 were applied....
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Drug-drug interaction potential of antitumor acridine agent C-1748: The substrate of UDP-glucuronosyltransferases 2B7, 2B17 and the inhibitor of 1A9 and 2B7
PublikacjaBackground The compound 9-(2′-hydroxyethylamino)-4-methyl-1-nitroacridine (C-1748), the promising antitumor agent developed in our laboratory was determined to undergo phase I metabolic pathways. The present studies aimed to know its biotransformation with phase II enzymes – UDP-glucuronosyltransferases (UGTs) and its potential to be engaged in drug-drug interactions arising from the modulation of UGT activity. Methods UGT-mediated...
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Cable-stayed cantilever structures as an expat of unique application in the construction of a building located in seismic area – an author’s project of multifunctional building in Lisbon, Portugal
PublikacjaThe article presents numerical simulations for the modelling of seismic impact on the structure of unique cantilever cablestayed structure with application of two methods. The Response Spectrum method, in which a spectrum of the structure's responses to an earthquake's impact is generated and the Accelerogram method, in which we generate dynamic load in the form of a diagram of the connection between acceleration and time for...
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Sprawczość vs wspólnotowość w postrzeganiu zespołów zróżnicowanych kulturowo
PublikacjaArtykuł dotyczy problematyki postrzegania i oceny zalet i wad pracy w zespołach zróżnicowanych kulturowo, a w szczególności psychospołecznych wymiarów takiej oceny. Wyniki dotychczasowych badań wskazują, że decyzja o możliwości współpracy z innymi ludźmi poprzedzana jest oceną dokonywaną w odniesieniu do dwóch podstawowych wymiarów wartościowania: sprawczości i wspólnotowości. Koncentracja na efektywności działania ukierunkowanego...
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Mrówczan sodu z nowym pakietem inhibitorów korozji jako ekologiczny środek do odladzania infrastruktury lotniczej.
PublikacjaPrzedstawiono wyniki badań korozji kadmowej powłoki na stali oraz korozji po zanurzeniu stopów metali w mrówczanie sodu z nowym pakietem inhibitorów korozji, zawierającym synergiczną kompozycję poliasparaginianu sodu oraz imidazolu. Ponadto wyznaczono zdolność penetracji lodu przez badany układ. Właściwo- ści opracowanej kompozycji odladzającej porównano z właściwościami środków dostępnych na rynku. Uzyskane wyniki wskazują, że otrzymany...
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Central European Journal of Sport Sciences and Medicine
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International Journal of Sport Management Recreation and Tourism
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Palestrica Mileniului III - Civilizatie si Sport
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Journal of Imagery Research in Sport and Physical Activity
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Facta Universitatis Series Physical Education and Sport
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Asia Pacific Journal of Sport and Social Science
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INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM
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Journal of Hospitality Leisure Sport & Tourism Education
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Raport z badań podczas próbnego obciążenia wiaduktu drogowego WD-4 nad projektowaną obwodnicą Kościerzyny w ciągu DK 20, w ciągu DW 214
PublikacjaW pracy przedstawiono metodykę pomiarów i wyniki badań statycznych i dynamicznych podczas próbnego obciążenia wiaduktu drogowego WD-4 nad projektowaną obwodnicą Kościerzyny w ciągu DK 20, w ciągu DW 214. Sformułowano wnioski dotyczące rzeczywistej pracy konstrukcji i warunków dalszej eksploatacji obiektu.
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Management Strategy for Seaports Aspiring to Green Logistical Goals of IMO: Technology and Policy Solutions
PublikacjaRecently, because of serious global challenges including the consumption of energy and climate change, there has been an increase in interest in the environmental effect of port operations and expansion. More interestingly, a strategic tendency in seaport advancement has been to manage the seaport system using a model which balances environmental volatility and economic development demands. An energy efficient management system...
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Differences in Expression of Genes Involved in Bone Development and Morphogenesis in the Walls of Internal Thoracic Artery and Saphenous Vein Conduits May Provide Markers Useful for Evaluation Graft Patency
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Wystawa pokonkursowa "Apartament Gdyński" w ramach III Weekendu Architektury w Gdyni 2013 r., organizowany przez Miasto Gdynia i Agencję Rozwoju Gdyni
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Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia
PublikacjaInduction of proteins involved in drug metabolism and in drug delivery has a significant impact on drug-drug interactions and on the final therapeutic effects. Two antitumor acridine derivatives selected for present studies, C-1748 (9-(2’-hydroxyethylamino)-4-methyl-1-nitroacridine) and C-1305 (5-dimethylaminopropylamino-8-hydroxy-triazoloacridinone), expressed high and low susceptibility to metabolic transformations with liver...
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Rocznik Hydrogeologiczny Państwowej Służby Hydrogeologicznej
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Autonomous port management based AGV path planning and optimization via an ensemble reinforcement learning framework
PublikacjaThe rapid development of shipping trade pushes automated container terminals toward the direction of intelligence, safety and efficiency. In particular, the formulation of AGV scheduling tasks and the safety and stability of transportation path is an important part of port operation and management, and it is one of the basic tasks to build an intelligent port. Existing research mainly focuses on collaborative operation between...
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Conditions of Iranian international trade in terms of lifting the sanctions: A case study of Polish-Iranian trade perspectives
PublikacjaThe main aim of the paper is to identify the areas and determine the feasibility of trade between Polish and Iranian companies in relation to historical and cultural conditions. The authors describe the complexity of the issue of foreign trade, the determinants of relations between Poland and the Islamic Republic of Iran, and the Iranian economy – its features, strengths and weaknesses, and consequences of the recent UN, EU, and...
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JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
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The absorption and fluorescence spectra of C-1305 derivatives (IKE1-IKE8), potential antifungal agents
Dane BadawczeOptical measurements of C-1305 derivatives (IKE1-IKE8). The absorption spectra were recorded at 300 - 800 nm for solutions with 16 μg / mL derivative concentration. The fluorescence emission spectra were determined at 420-800 nm with the excitation wavelengths 360 or 415 nm for solutions with 1 μg / mL derivative concentration. All measurements were...
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The Challenge of Quantification: An Interdisciplinary Reading
PublikacjaThe present work looks at what we call “the multiverse of quantification”, where visible and invisible numbers permeate all aspects and venues of life. We review the contributions of different authors who focus on the roles of quantification in society, with the aim of capturing different and sometimes separate voices. Several scholars, including economists, jurists, philosophers, sociologists, communication and data scientists,...
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Student model representation for pedagogical virtual mentors
PublikacjaThe paper concerns technological aspects of virtual mentors construction, especially concentrating on the student model representation. The article distinguishes several types of information that is gathered by the pedagogical agents and other educational platforms, including student knowledge model, student progress tracking, interaction process patterns and learner preferences. A set of technologies used for the student model...
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Rafał Leszczyna dr hab. inż.
OsobyDr hab. inż. Rafał Leszczyna jest profesorem uczelni na Wydziale Zarządzania i Ekonomii Politechniki Gdańskiej. W lipcu 2020 r., na podstawie osiągnięcia naukowego w obszarze zarządzania cyberbezpieczeństwem infrastruktur krytycznych w sektorze elektroenergetycznym, uzyskał stopień doktora habilitowanego w dziedzinie nauk inżynieryjno-technicznych, dyscyplina informatyka techniczna i telekomunikacja. W latach 2004–2008 pracował...
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Particle swarm optimization algorithms for autonomous robots with deterministic leaders using space filling movements
PublikacjaIn this work the swarm behavior principles of Craig W. Reynolds are combined with deterministic traits. This is done by using leaders with motions based on space filling curves like Peano and Hilbert. Our goal is to evaluate how the swarm of agents works with this approach, supposing the entire swarm will better explore the entire space. Therefore, we examine different combinations of Peano and Hilbert with the already known swarm...
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Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis
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Power of the SMR brainwaves in the mental imagery experiment in sport: the "Fitness Activity" scenario.
Dane BadawczeThe data were collected to perform research on the neural oscillation during mental imagery in sport. The main aim of the study was to examine the cortical correlates of imagery depending on instructional modality (guided vs self-produced) using various sport-related scripts. The research was based on the EEG signals recorded during the session with...
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Power of the SMR brainwaves in the mental imagery experiment in sport: the "Slow Start" scenario.
Dane BadawczeThe data were collected to perform research on the neural oscillation during mental imagery in sport. The main aim of the study was to examine the cortical correlates of imagery depending on instructional modality (guided vs self-produced) using various sport-related scripts. The research was based on the EEG signals recorded during the session with...
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Power of the SMR brainwaves in the mental imagery experiment in sport: the "Successful Competition" scenario.
Dane BadawczeThe data were collected to perform research on the neural oscillation during mental imagery in sport. The study's main aim was to examine the cortical correlations of imagery depending on instructional modality (guided vs self-produced) using various sport-related scripts. The research was based on the EEG signals recorded during the session with the...
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Power of the SMR brainwaves in the mental imagery experiment in sport: the "Training Session" scenario.
Dane BadawczeThe data were collected to perform research on the neural oscillation during mental imagery in sport. The study's main aim was to examine the cortical correlations of imagery depending on instructional modality (guided vs self-produced) using various sport-related scripts. The research was based on the EEG signals recorded during the session with the...
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Raport z badań podczas próbnego obciążenia konstrukcji w torze nr 1 i 2 wiaduktu kolejowego w km 20,151 LK 353 w m. Pobiedziska
PublikacjaW pracy przedstawiono metodykę pomiarów i wyniki badań statycznych podczas próbnego obciążenia konstrukcji w torze nr 1 i 2 wiaduktu kolejowego w km 20,151 LK 353 w m. Pobiedziska. Sformułowano wnioski dotyczące rzeczywistej pracy konstrukcji i warunków dalszej eksploatacji obiektu.
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2,7-Dihydro-3H-pyridazino[5,4,3-kl]acridin-3-one derivatives, novel type of cytotoxic agents active on multidrug-resistant cell lines. Synthesis and biological evaluation.
PublikacjaOtrzymano serię pirydazyno akrydyn-3-onów w reakcji 9-okso-9,10-dihydroakrydyno-1-karboksylanu etylu z POCl3, następnie dodanie odpowiedniej alkiloaminoalkilohydrazyny. Badane związki wykazują w porównaniu z referencyjnymi cytostatykami DX, MIT niższe wartości indeksu RI, a także niższe aktywności cytotoksyczne.
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Human CYP2 family of cytochrome P-450 takes part in metabolism of two acridine antitumor agents, C-1311 and C-1748, selected for I phase of clinical trials
PublikacjaPraca zawiera wyniki badań metabolicznej transformacji przeciwnowotworowych pochodnych akrydyny wobec zestawu 16 prób enzymów mikrosomalnych, pochodzących z wątroby 16 różnych pacjentów. Wykazano, że za metabolizm tych związków u człowieka odpowiedzialne są głównie izoenzymy z rodziny CYP2.
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Study of the Effectiveness of Model Order Reduction Algorithms in the Finite Element Method Analysis of Multi-port Microwave Structures
PublikacjaThe purpose of this paper is to investigate the effectiveness of model order reduction algorithms in finite element method analysis of multi-port microwave structures. Consideration is given to state of the art algorithms, i.e. compact reduced-basis method (CRBM), second-order Arnoldi method for passive-order reduction (SAPOR), reduced-basis methods (RBM) and subspace-splitting moment-matching MOR (SSMM-MOR)
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An MOR Algorithm Based on the Immittance Zero and Pole Eigenvectors for Fast FEM Simulations of Two-Port Microwave Structures
PublikacjaThe aim of this article is to present a novel model-order reduction (MOR) algorithm for fast finite-element frequency-domain simulations of microwave two-port structures. The projection basis used to construct the reduced-order model (ROM) comprises two sets: singular vectors and regular vectors. The first set is composed of the eigenvectors associated with the poles of the finite-element method (FEM) state-space system, while...
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Three-Dimensional Thematic Map Imaging of the Yacht Port on the Example of the Polish National Sailing Centre Marina in Gdańsk
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Big Data and the Internet of Things in Edge Computing for Smart City
PublikacjaRequests expressing collective human expectations and outcomes from city service tasks can be partially satisfied by processing Big Data provided to a city cloud via the Internet of Things. To improve the efficiency of the city clouds an edge computing has been introduced regarding Big Data mining. This intelligent and efficient distributed system can be developed for citizens that are supposed to be informed and educated by the...
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Intelligent Virtual Agents
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