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Wyniki wyszukiwania dla: GENE DUPLICATION
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Silicon carbide application issues
PublikacjaThe main goals of Task 3 and Task 4 of the ordered project ''New technologies based on silicon carbide and their application in HF, high power and high temperature electronics'' are presented
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Application of nanofluids in thermal technologies
PublikacjaNanofluids it is a relatively new category of thermal fluids that can serve as coolants, both in single- and two phase systems. However application of nanofluids in industrial applications requires faultless their thermophysical properties. Existing models originally developed for liquid/solid particles mixtures (slurries) fail in case of nanofluids. Moreover correlations used to calcuate heat transfer coefficients of conventional...
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Methyl jasmonate as a control factor of the synthase squalene gene promoter and ginsenoside production in American ginseng hairy root cultured in shake flasks and a nutrient sprinkle bioreactor
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Impact of heat shock transcription factor 1 on global gene expression profiles in cells which induce either cytoprotective or pro-apoptotic response following hyperthermia
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Cation homeostasis and transport related gene markers are differentially expressed in porcine buccal pouch mucosal cells during long-term cells primary culture in vitro
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High pressure processing, acidic and osmotic stress increased resistance to aminoglycosides and tetracyclines and the frequency of gene transfer among strains from commercial starter and protective cultures
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Integrating Statistical and Machine‐Learning Approach for Meta‐Analysis of Bisphenol A‐Exposure Datasets Reveals Effects on Mouse Gene Expression within Pathways of Apoptosis and Cell Survival
PublikacjaBisphenols are important environmental pollutants that are extensively studied due to different detrimental effects, while the molecular mechanisms behind these effects are less well understood. Like other environmental pollutants, bisphenols are being tested in various experimental models, creating large expression datasets found in open access storage. The meta‐analysis of such datasets is, however, very complicated for various...
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Molecular differences in mitochondrial DNA (mtDNA) genomes of dogs with malignant mammary tumours
Dane BadawczeThe aim of this study was to determine molecular defects in mitochondrial DNA with the use of large-scale genome analysis in malignant canine mammary gland tumours and indicate whether these changes were linked with the carcinogenesis process. With the use of the NGS technology, we sequenced 27 samples of mtDNA isolated from blood and tumours obtained...
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Gene Therapy and Molecular Biology
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Journal of Women's Health (GEN B)
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Removal of selected sulfonamides and sulfonamide resistance genes from wastewater in full-scale constructed wetlands
PublikacjaSulfonamides are high-consumption antibiotics that reach the aquatic environment. The threat related to their presence in wastewater and the environment is not only associated with their antibacterial properties, but also with risk of the spread of drug resistance in bacteria. Therefore, the aim of this work was to evaluate the occurrence of eight commonly used sulfonamides, sulfonamide resistance genes (sul1–3) and integrase genes...
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Phytoecdysteroid containing plants – a source of bioactive compounds with potential anticarcinogenic effects
PublikacjaEcdysteroids are a group of steroids synthesized in inver- tebrates as molting hormones and also in some plants as secondary metabolites acting as a defense against parasites. These compounds do not naturally occur in mammals and are not structurally related to mammalian steroid hor- mones, consequently do not activate mammalian hormone receptors. Ecdysteroids exhibit very low toxicity to mam- mals and to date no serious side effects...
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Processing and Application of Ceramics
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Lighting Design and Application
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Haloperidol, but not olanzapine, may affect expression of PER1 and CRY1 genes in human glioblastoma cell line
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A role for accessory genes rI.-1 and rI.1 in the regulation of lysis inhibition by bacteriophage T4
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Coexistence of HFE and rare UGT1A1 genes mutations in patients with iron overload related liver injury
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A different methylation profile of circadian genes promoter in breast cancer patients according to clinicopathological features
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P.238 Lithium treatment modulates the expression of inflammation involved genes in major depressive disorder
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Increased Expression of Several Collagen Genes is Associated with Drug Resistance in Ovarian Cancer Cell Lines
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Expression Changes in Fatty acid Metabolic Processrelated Genes in Porcine Oocytes During in Vitro Maturation
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Altered Expression of ESR1, ESR2, PELP1 and c-SRC Genes Is Associated with Ovarian Cancer Manifestation
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Enterococci isolated from plant-derived food - Analysis of antibiotic resistance and the occurrence of resistance genes
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Hyponastic Leaves 1 Interacts with RNA Pol II to Ensure Proper Transcription of MicroRNA Genes
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Total impact of oxidative stress genes on cardiovascular events—a 7-year follow-up study
PublikacjaCardiovascular (CV) events are the number one cause of lifetime disability and deaths worldwide. It is well known that traditional risk factors do not fully correlate with clinical outcomes; therefore, searching for other markers that would explain CV events occurrence seems essential. Of importance, one of the main factors at the origin of CV events is oxidative stress, causing inflammation and atherosclerotic plaque instability....
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Elgold: gold standard, multi-genre dataset for named entity recognition and linking
Dane BadawczeThe dataset contains 276 multi-genre texts with marked named entities, which are linked to corresponding Wikipedia articles if available. Each entity was manually verified by at least three people, which makes the dataset a high-quality gold standard for the evaluation of named entity recognition and linking algorithms.
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Differential and Overlapping Effects of 20,23(OH)2D3 and 1,25(OH)2D3 on Gene Expression in Human Epidermal Keratinocytes: Identification of AhR as an Alternative Receptor for 20,23(OH)2D3
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Germline DNA Retention in Murine and Human Rearranged T Cell Receptor Gene Coding Joints: Alternative Recombination Signal Sequences and V(D)J Recombinase Errors
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Cytokine TGFβ Gene Polymorphism in Asthma: TGF-Related SNP Analysis Enhances the Prediction of Disease Diagnosis (A Case-Control Study With Multivariable Data-Mining Model Development)
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Sequences of large subunit ribosomal RNA gene, partial sequence encoding D1/D2 domain of psychrotolerant pigment-producing yeast-like fungi
Dane BadawczeDNA fragments encoding D1/D2 domain of large subunit ribosomal RNA of psychrotolerant pigment-producing yeast-like fungi named Red, Pink and Black were PCR amplified using NL1 5’ GCATATCAATAAGCGGAGGAAAAG 3’ and NL4 5’ GGTCCGTGTTTCAAGACGG 3’ primers and sequenced by Sanger method using the same primers.
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Comparative studies of the Acinetobacter genus and the species identification method based on the recA sequences
PublikacjaZaproponowano metodę genotypowania bakterii rodzaju Acinetobacter, opartą o analizę sekwencji genów recA, amplifikację fragmentów genu recA i analizę profili fragmentów restrykcyjnych po cięciu produktów reakcji PCR enzymami restrykcyjnymi (recA PCR/RFLP). Profile RFLP otrzymane za pomocą enzymu Tsp509I są użyteczne w identyfikacji poszczególnych gatunków bakterii rodzaju Acinetobacter. Na podstawie analizy otrzymanych sekwencji...
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Intra-operative biopsy in chronic sinusitis detects pathogenic Escherichia coli that carry fimG/H, fyuA and agn43 genes coding biofilm formation
PublikacjaThe aim of this study was to investigate whether or not surgical biopsy of sinus tissue in chronic sinusitis, not responsive to treatment, would detect E. coli. We intended to evaluate E. coli virulence genes, therefore dispute the causal role of such an unusual microorganism in chronic sinusitis, as well as consider effective pathogen-targeted therapy. Patients with E. coli isolated by intra-operative puncture biopsy were included...
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Novel staphylococci nucH taxonomical marker used in identification of human-associated Staphylococcus succinus subsp. casei
PublikacjaThe aim of our study was to assess the sequencing of unique nucH gene fragment based on performed bioinformatics analysis as a novel diagnostic method for the identification of difficult to identify staphylococcal human pathogenic strains. Initially, PCR-RFLP-rrn analysis specific to the spacers between 16SrDNA and 23SrDNA followed by HhaI restriction analysis was performed. Further, sequencing of nucH and 16S rDNA genes fragments...
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The Application of Submerged Modules for Membrane Distillation
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New results for online page replication.
PublikacjaW artykule zbadano problem replikacji stron dokonywanej w trybie on-line. Przedstawiono nowy randomizowany algorytm dla sieci pętlowych, który jest lepszy niż najlepszy dotąd znany. Poprawiono dolne oszacowania dla tego problemu. Pokazano możliwe rozszerzenia tego modelu przetwarzania. Pokazano, że prowadzi to do uproszczenia dowodów szeregu znanych twierdzeń.
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Application of chemometric methods in environmental research.
PublikacjaW badaniach analitycznych zastosowanie nowoczesnych technik pomiarowych, połączone ze skróceniem czasu analiz, prowadzi do uzyskiwania obszernych zbiorów danych w stosunkowo krótkim czasie. Zastosowanie specjalnych technik obróbki zbiorów wyników pomiarowych sprawia, że możliwe jest ''wydobycie'' dodatkowych informacji z posiadanych danych. Idealnym narzędziem do tego typu zabiegów może być chemometria. W opracowaniu omówiono teorię...
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Trunked Radio Solutions for Special Application
PublikacjaIn the paper modern concepts of radio communication trunking-dispatch systems for special applications are presented. Basic standards of TETRA, DMR, and cdma2000 are mentioned. The aim of the paper is to present innovative trunking solutions based on the LTE system working both in FDD and TDD mode. The architecture of LTE trunked radio is shown as well as new services possible to implementation are described. The way of TETRA and...
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Application of ionic liquids in chromatographic techniques
PublikacjaCiecze jonowe (ang. Ionic Liquids, ILs) z uwagi na swoje unikalne właściwości fizyko – chemiczne oraz możliwość prostej modyfikacji budowy, w znacznym stopniu przyczyniły się do rozwoju technik rozdzielania. W chromatografii gazowej fazy stacjonarne w postaci cieczy jonowych stanowią istotne uzupełnienie istniejących faz stacjonarnych na bazie polisiloksanów i glikolu polietylenowego. Ze względu na wysoką stabilność termiczną...
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Application of total parameters in environmental analytics
PublikacjaPrzedstawiono klasyfikację technik oznaczania tzw. parametrów sumarycznych w próbkach środowiskowych (powietrze, woda, gleba) oraz obszar wykorzystania parametrów sumarycznych w analityce środowiskowej.
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Application of discriminant analysis to feature extraction.
PublikacjaPierwotnie uzyskiwane wektory cech są wysokowymiarowe. Redukcja wymiarowości jest często osiągana poprzez transformacje przestrzeni cech. Niniejsza praca prezentuje uogólnione kryterium Fishera i jego podstawowe własności, dyskutowana jest także możliwość wyprowadzania i oceny heurystycznych metod ekstrakcji cech. Przedstawiono również nowy sekwencyjny algorytm selekcji cech dyskryminacyjnych.
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Application of microwaves for sewage sludge conditioning
PublikacjaArtykuł dotyczy wpływu promieniowania mikrofalowego na odwadnianie osadów ściekowych. Przeprowadzono pomiary parametrów charakteryzujących podatność osadów ściekowych na odwadnianie: opór właściwy, czas ssania kapilarnego oraz zawartość suchej masy w osadzie po odwirowaniu. Stwierdzono poprawę odwadnialności osadów kondycjonowanych promieniowaniem mikrofalowym, zależną ilościowo od rodzaju preparowanych osadów. Zastosowanie podwójnego...
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Chaboche model - development and fe application
PublikacjaCelem artykułu jest prezentacja rozwoju i numerycznej aplikacji sprężysto-lepkoplastycznego modelu Chabocha. Przedstawione są szczegółowe opisy kilku wariantów modelu wraz z parametrami materiałowymi. Dynamiczna analiza kołowej płyty stalowej, która jest porównywana z wynikami eksperymentalnymi, ilustruje praktyczne zastosowanie opisywanego modelu. Do wprowadzenia modelu Chabocha do komercyjnego programu MSC.Marc użyta jest procedura...
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Testing and tuning PLC application programs
PublikacjaWe wstępie zawarto kilka uwag autora dotyczących pilnej potrzeby wdrażania na Wydziale Mechanicznym idei mechatronicznego kształcenia. Przedstawiono przegląd sposobów monitorowania i testowania programów aplikacyjnych PLC podczas budowania lub modernizacji systemów sterowania. Przedyskutowano zakres zastosowań oraz ograniczenia poszczególnych sposobów. Opisano przykład zastosowania zbudowanego stanowiska do eksperymentalnych testów...
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The Optimum Dataset method – examples of the application
PublikacjaData reduction is a procedure to decrease the dataset in order to make their analysis more effective and easier. Reduction of the dataset is an issue that requires proper planning, so after reduction it meets all the user’s expectations. Evidently, it is better if the result is an optimal solution in terms of adopted criteria. Within reduction methods, which provide the optimal solution there is the Optimum Dataset method (OptD)...
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Computer application for railway track realignment
PublikacjaThe topic of this article is the issue of railway track realignment. For this purpose, a computer software application was created that supports computations and generates a report needed for regulation of the trajectory of the railway. This program gives the ability to import data from measurement of the railway trajectory and then perform the calculation of the mathematical realignment. The result of this calculation is the basis...
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Application of nanofluids in selected thermal technologies
PublikacjaSome peculiarities regarding convective heat transfer of nanofluids are presented. Particularly, results of the fundamental research concerning pool boiling and single phase convection of nanofluids as well as data obtained for selected heat exchangers operated with nanofluids are discussed.
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Quality of Test Specification by Application of Patterns
PublikacjaEmbedded system and software testing requires sophisticated methods, which are nowadays frequently supported by application of test patterns. This eases the test development process and contributes to the reusability and maintainability of the test specification. However, it does not guarantee the proper level of quality and test coverage in d ifferent dimensions of the test specification. In this paper the quality of the test...
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Modeling SPMD Application Execution Time
PublikacjaParallel applications in a Single Process Multiple Data paradigm assume splitting huge amounts of data to multiple processors working in parallel at small data packets. As the individual data packets are not independent, the processors must interact with each other to exchange results of the calculations with their adjacent partners and take these results into account in their own computations. An example of SPMD is geometric parallelism...
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Modeling DAC Application Execution Time
PublikacjaAn application written in the Divide And Conquer paradigm is more difficult to model than SPMD application because of complex algorithm, causing use of many coefficients in a computational complexity function. Processors are divided into various layers, each layer contains different number of processors. Data packets processed in different layers and transferred between layers have different length. Moreover first layer processors use...
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APPLICATION OF MAGNETIC NANOPARTICLES FOR WATER TREATMENT
PublikacjaIn this study magnetic nanoparticles were fabricated and used for water treatment. Nanoparticles were prepared in two ways. The first one involved NiZn ferrite nanoparticles synthesized by co-precipitation of metal cations with sodium hydroxide at high temperature. The second one featured maghemite nanoparticles was prepared by saltassisted solid-state reaction. Modification and functionalization of nanoparticles surface was investigated....