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Search results for: mechanism of azole resistance
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Active Linear Tunable Resistance Element and Application to Feedforward Linearization of CMOS Transconductance Amplifier
PublicationW pracy przedstawiono koncepcję układową przestrajalnego rezystora liniowego MOS wykorzystującego tranzystory pracujące w zakresie triodowym. Opracowana struktura, jak wykazały symulacje komputerowe, charakteryzuje się dobrymi właściwościami zarówno jeżeli chodzi o zakres przestrajania jak i liniowość charakterystyk przejściowych. Pozwoliło to efektywnie wykorzystać prezentowany element do linearyzacji operacyjnego wzmacniacza...
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Monte Carlo simulations of the fracture resistance degradation of asphalt concrete subjected to environmental factors
PublicationThe paper presents the results of laboratory tests of SCB (semi-circular beam) samples of asphalt concrete, subjected to the destructive effect of water and frost as well as the aging processes. The determined values of material parameters show significant dispersions, which makes the design of mixtures difficult. Statistical analysis of the test results supplemented by computer simulations made with the use of the proprietary...
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The impedance method of monitoring the degradation of rubber linings in applications where progressive deterioration is the predominant failure mechanism
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Analysis of load carrying capacity and destruction mechanism of an intermediate anchorage steel plate for pillar jib crane
PublicationPillar jib cranes are often mounted to existing floors with the use of an intermediate anchorage steel plate instead of using independent foundations, what is shown in the figure. Standards for steel design provide only basic rules for the design of such an intermediate plate. This study presents a simple design approach by using a numerical model in order to analyze different parameters that have significant influence in the anchorage...
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Preparation and photocatalytic activity of Nd-modified TiO2 photocatalysts: Insight into the excitation mechanism under visible light
PublicationTitanium dioxide (TiO2) nanoparticles (NPs) modified with neodymium (Nd) in the range between 0.1 and 1.0 mol% were prepared via the hydrothermal method. The samples obtained were characterized by diffuse reflectance spectroscopy (DRS), scanning electron microscopy (SEM), X-ray fluorescence (EDX), Brunauer–Emmett–Teller (BET) method, X-ray powder diffraction analysis (XRD), X-ray photoelectron spectroscopy (XPS) and photoluminescence...
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The Potential Mechanism of Tiliroside-Dependent Inhibition of t-Butylhydroperoxide-Induced Oxidative Stress in Endometrial Carcinoma Cells
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Oscillatory Mechanism of α-Fe(N) ↔ γ’-Fe4N Phase Transformations during Nanocrystalline Iron Nitriding
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Molecular simulations study of ligand-release mechanism in an odorant-binding protein from the southern house mosquito
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Strengthening mechanism and precipitate evolution of a multi-application special engineering steel designed based on a hybrid idea
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Nanocomposites of Graphene Oxide—Silver Nanoparticles for Enhanced Antibacterial Activity: Mechanism of Action and Medical Textiles Coating
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267: Mesenchymal cells regulate growth of intestinal crypts by a Wnt independent mechanism in 3D culture system
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Mollecular mechanism and chemicl kinetic description of nitrobenzene liquid membrane oscillator containing benzyldimethyltetradecylammonium chloride surfactant
PublicationBadano oscylacje róznicy potencjału między fazami wodnymi oscylatora z nitrobenzenową membraną ciekłą zawierającego chlorek benzylodimetylotetradecyloamoniowy. Opisano chemię fizyczną tego oscylatora oraz omówiono rolę efektów hydrodynamicznych w powstawaniu oscylacji. Zaproponowano nowy mechanizm oparty na transferze masy par jonowych. Oscylacje są generowane na granicy faza akceptowa/ membrana ciekła i są spowodowane autokatalityczną...
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Comparison of radical-driven technologies applied for paraben mixture degradation: mechanism, biodegradability, toxicity and cost assessment
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Mechanism of recognition of parallel G-quadruplexes by DEAH/RHAU helicase DHX36 explored by molecular dynamics simulations
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A Single Mutation in a Tunnel to the Active Site Changes the Mechanism and Kinetics of Product Release in Haloalkane Dehalogenase LinB*
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Isoform-specific inhibition of DNA topoisomerase II as the mechanism of action of novel anticancer agent C-1305
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Influence of energy absorbers on Malgaigne fracture mechanism in lumbar-pelvic system under vertical impact load
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Mechanism of recognition of parallel G-quadruplexes by DEAH/RHAU helicase DHX36 explored by molecular dynamics simulations
PublicationBecause of high stability and slow unfolding rates of G-quadruplexes (G4), cells have evolved specialized helicases that disrupt these non-canonical DNA and RNA structures in an ATP-dependent manner. One example is DHX36, a DEAH-box helicase, which participates in gene expression and replication by recognizing and unwinding parallel G4s. Here, we studied the molecular basis for the high affinity and specificity of DHX36 for parallel-type...
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Chemical kinetic approach to the mechanism of coupled transport of Cu(II) Ions through bulk liquid membranes
PublicationW celu lepszego zrozumienia transportu jonów miedzi przez ciekłe membrany zaproponowano schemat kinetyczny na poziomie molekularnym oparty o dwie nastepujące po sobie reakcje odwracalne. Zasegurowano uzywając membrany ciekłej o wysokiej polarności i polaryzowalności oraz szybkiego mieszania mozna zwiekszyć wydajnośc transportu.
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Filter-Hilbert Method for Automatic Correction of Non-Anechoic Antenna Measurements with Embedded Self-Calibration Mechanism
PublicationOne of the most important steps in the process of antenna development involves measurements of its prototype. Far-field performance of radiators is normally characterized in strictly controlled environments such as anechoic chambers which can ensure certification-grade accuracy. Unfortunately, they are also characterized by high construction costs which might not be justified for low-budget research and/or teaching-related activities....
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Enhancement of photocatalytic-based processes by mono- and bimetallic (CuPd) rutile loaded nanoparticles for antibiotic resistance genes and facultative pathogenic bacteria removal
PublicationThe aim of the study was the strong reduction of facultative pathogenic bacteria (FPB), and clinically relevant antibiotic resistance genes (ARGs) from secondary effluent. To evaluate the ARGs removal efficiency comparative study of individual unit processes and combined AOPs has been performed. The present work investigated: i) removal of selected ARGs, namely blaTEM, ermB, qnrS, tetM, five FPB as well as 16S rDNA and the integrase...
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The effect of the wood temperature upon specific cutting resistance during machining with narrow-kerf saws
PublicationW pracy przedstawiono wyniki badań eksperymentalnych właściwego powierzchniowego oporu skrawania drewna sosny w funkcji wilgotności drewna, temperatury drewna oraz prędkości posuwu podczas przecinania cienkimi piłami. Proces cięcia prowadzono na pilarce ramowej wielopiłowej PRW15M. Sosnowe próbki przed badaniami mrożono w komorze klimatycznej - temperatura drewna -5 C deg., -20 C deg., +20 C deg. Czas wymrażania przed próbami określano...
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Scuffing and rolling contact fatigue resistance of discrete laser spot hardened austempered ductile iron
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The problems of resistance to scuffing of heavily loaded lubricated friction joints with WC/C-coated parts
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Non-Pharmacological Treatments for Insulin Resistance: Effective Intervention of Plant-Based Diets—A Critical Review
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The impact of resistance exercise range of motion on the magnitude of upper-body post-activation performance enhancement
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Virulence and Drug-Resistance of Staphylococcus aureus Strains Isolated from Venous Ulcers in Polish Patients
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Recycled polyethylene and crumb rubber composites modified asphalt with improved aging resistance and thermal stability
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Fabrication, Microstructure and High Temperature Corrosion Resistance of Porous Alloys for Solid Oxide Fuel Cells
PublicationPorous alloys find use in modern Solid Oxide Fuel Cells as the supporting structures. As they are exposed to high temperatures (> 500°C) an oxide scale forms on their surface due to high temperature corrosion phenomena. Since the ratio between the surface area and volume is much higher than for planar samples, formation of the oxide can lead to a breakaway oxidation after relatively short times. Therefore corrosion properties of...
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Comparison of buckling resistance of columns modelled by beam and shell elements using non-linear analysis
PublicationThe aim of the paper is to investigate the stability process in the axially compressed columns modelled by beam and shell elements using static and dynamic finite element analysis by taking both the geometric and material non-linearity into account. The perfect columns and columns with geometric imperfections were analysed. The differences between the results of static and dynamic analyses in shell and beam models were discussed.
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Effects of Laser Remelting at Cryogenic Conditions on Microstructure and Wear Resistance of the Ti6Al4V Alloy Applied in Medicine
PublicationThe titanium and its alloys can be subjected to surface treatment, including laser treatment. In this work a new laser treatment at cryogenic conditions of Ti6Al4V alloy has been described. The work has been aimed at establishing whether such surface treatment could be suitable for implants working under wear in biological corrosive environment. The remelting has been made with the use of CO2 continuous work laser at laser power...
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Resistance changes of carbon nanotubes decorated with platinum nanoparticles in the presence of hydrogen at different and constant concentrations
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Increased Expression of Several Collagen Genes is Associated with Drug Resistance in Ovarian Cancer Cell Lines
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Contrast Tempo of Movement and Its Effect on Power Output and Bar Velocity During Resistance Exercise
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Study of the selection mechanism of heavy metal (Pb 2+, Cu 2+, Ni 2+ and Cd2+) adsorption on clinoptilite
PublicationBadano proces adsorpcji jonów metali ciężkich (w warunkach statycznych) z wodnych roztworów jednoskładnikowych i wieloskładnikowych na klinoptylolicie zarówno surowym jak i po wstępnej obróbce. Proces sorpcji ma charakter procesu jonowymiennego i składa sie z trzech etapów:- adsorpcji na powierzchni mikokryształów,- inwersji,- adsorpcji wewnątrz mikrokryształów.Proces sorpcji może być dobrze opisany zarówno za pomocą modelu Frendlicha...
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Apatite-coated Ag/AgBr/TiO2 nanocomposites: Insights into the antimicrobial mechanism in the dark and under visible-light irradiation
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Comparison of the effect of montmorillonite, magnesium hydroxide and a mixture of both on the flammability properties and mechanism of char formation of HDPE composites
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Novel 2019 coronavirus structure, mechanism of action, antiviral drug promises and rule out against its treatment
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Insight into the microbial and genetic response of anammox biomass to broad range concentrations of different antibiotics: Linking performance and mechanism
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Pollution characteristics, mechanism of toxicity and health effects of the ultrafine particles in the indoor environment: Current status and future perspectives
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Activation mechanism and activity of globupain, a thermostable C11 protease from the Arctic Mid-Ocean Ridge hydrothermal system
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High energy radiation – Induced cooperative reductive/oxidative mechanism of perfluorooctanoate anion (PFOA) decomposition in aqueous solution
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A robust optimization model for affine/quadratic flow thinning: A traffic protection mechanism for networks with variable link capacity
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Chemically Bonded Silica Stationary Phases: Synthesis, Physicochemical Characterization, and Molecular Mechanism of Reversed-Phase HPLC Retention
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Imidazoacridinone antitumor agent, c-1311, as a selective mechanism-based inactivator of human recombinant cytochrome P450 1A2
PublicationPrzedmiotem badań była przeciwnowotworowa pochodna imidazoakrydonu, C-1311, która pod nazwą Symadex R, znajduje się aktualnie w II fazie badań klinicznych. Wcześniejsze wyniki pozwoliły stwierdzić, że związek ten jest selektywnym inhibitorem niektórych enzymów cytochromowych. Podjęto zatem próbę wyjaśnienia mechanizmu inhibicji izoenzymów cytochromu P450 przez C-1311. Wykazano, że utrata aktywności katalitycznej obu izoenzymów...
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Determination of the adsorption mechanism of imidazolium type ionic liquids onto kaolinite: implications for their fate and transport in the soil environment
PublicationNiniejsza publikacja szczegółowo opisuje sorpcję cieczy jonowych na powierzchni glin kaolinowych. Uzyskane wyniki wskazują na występowanie zjawiska sorpcji wielowarstwowej. Przy całkowitym wysyceniu najwyższy współczynnik podziału został zaaobserwowany dla cieczy jonowych podstawionych długim łańcuchem alkilowym. Średnie wartości energii swobodnej wyznaczone dla procesu sorpcji cieczy jonowych są niższe niż typowe energie swobodne...
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Mechanism of selective anticancer activity of isothiocyanates relies on differences in DNA damage repair between cancer and healthy cells
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Mechanism of Solute and Thermal Characteristics in a Casson Hybrid Nanofluid Based with Ethylene Glycol Influenced by Soret and Dufour Effects
PublicationThis article models a system of partial differential equations (PDEs) for the thermal and solute characteristics under gradients (concentration and temperature) in the magnetohydrodynamic flow of Casson liquid in a Darcy porous medium. The modelled problems are highly non-linear with convective boundary conditions. These problems are solved numerically with a finite element approach under a tolerance of 10−8. A numerical algorithm...
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Prevention of resonance oscillations in gear mechanisms using non-circular gears
PublicationOne of the main disadvantages of gear mechanisms is the occurrence of noise and vibrations. This study investigated the applicability of non-circular gears for preventing resonance oscillations in gear mechanisms. The influence of a small deviation of the gear centrodes from the nominal circles on kinematic and oscillatory characteristics was analysed. It was shown that a larger deviation results in a smaller resonance amplitude...
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Unraveling the solar and visible light-induced deactivation mechanism of Pt-decorated carbon/TiO2 nanocomposite in photocatalytic hydrogen production
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