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Quantification of Compatibility Between Polymeric Excipients and Atenolol Using Principal Component Analysis and Hierarchical Cluster Analysis
PublicationAn important challenge to overcome in the solid dosage forms technology is the selection of the most biopharmaceutically efficient polymeric excipients. The excipients can be selected, among others, by compatibility studies since incompatibilities between ingredients of the drug formulations adversely affect their bioavailability, stability, efficacy, and safety. Therefore, new, fast, and reliable methods for detecting incompatibility...
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Apprendere camminando.Il metodo della Jane’s Walk per riscoprire San Lorenzo
PublicationTratta dal libro rivoluzionario che Jane Jacobs, attivista americana, ha scritto negli anni Sessanta e che ben presto è diventato un importante riferimento per la partecipazione dei cittadini nella progettazione urbana, questa citazione ben esprime l’approccio attraverso il quale ci siamo avvicinate alla riscoperta di San Lorenzo. Quartiere della città storica molto conosciuto, San Lorenzo si è rivelato in grado di disvelare paesaggi...
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Street Art and Urban Regeneration. Case Study Gdansk and Rome.
PublicationStreet art plays an important role in urban planning as a transforming engine to regenerate the public spaces and in the processes of participation. The article analyzes two main topics. The first one focuses on the urban serving as a support for spatial and cultural strategies in urban redevelopment projects. The second one is related to the potential of micro urban interventions as a strategy for a wider involvement of inhabitants...
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Physical crosslinking of hyaluronic acid in the presence of phospholipids in an aqueous nano-environment
PublicationHyaluronic acid and phospholipids are two components in the synovial joint cavity that contribute to joint lubrication synergistically. Molecular dynamics simulations were performed and hydrogen bonds in hyaluronic acid were analyzed to identify specific sites that are responsible for its physical cross-linking. Two molecular masses of hyaluronic acid, 10 kDa and 160 kDa, were considered. We use molecular dynamics simulations and...
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Mercury concentration in the sediments as a function of changing climate in coastal zone of Southern Baltic Sea – preliminary results
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Changes in conditions of acoustic wave propagation in the Gdansk deep as an effect of climate changes in the Baltic Sea region
PublicationThe article presents the results from a research project investigating acoustic climate changes in the Gdansk Deepbased on data extending from 1902 to 2019. This part of the southern Gotland Basin, is rarely discussed in thescientific literature.The speed of sound in the seawater is a function of temperature, salinity, and depth. In such shallow sea asBaltic Sea, the impact of depth is not substantial....
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Impact of climate and humans on the range dynamics of the woolly mammoth (Mammuthus primigenius) in Europe during MIS 2
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Mercury concentration in the sediments as a function of changing climate in coastal zone of Southern Baltic Sea – preliminary results
PublicationMercury, despite of its many uses in industry, is also highly toxic. It is highly neurotoxic, and because of the ability of mercury to penetrate placental barrier, in some countries ban on predatory fish consumption (the main route of mercury into human organism) by pregnant women was introduced. There are very little publications describing the consequences of weather anomalies on contaminants cycles. No research was published...
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The latest Jurassic–earliest Cretaceous climate and oceanographic changes in the Western Tethys: The Transdanubian Range (Hungary) perspective
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Divisional disparities on climate change adaptation and mitigation in Punjab, Pakistan: local perceptions, vulnerabilities, and policy implications
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Long-term operation of Kickuth-type constructed wetland applied to municipal wastewater treatment in temperate climate
PublicationThe purpose of this paper is to discuss the problem of changes of effectiveness of Kickuth-type constructed wetland with subsurface flow applied to domestic wastewater treatment. This study is based on an example of a wetland 3000 m2 in surface, serving 800 inhabitants, located in Poland. The results of chemical analysis showed that after an initial year of ‘start-up time’, the efficiency of pollutant removal gradually increased...
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THE ECONOMIC EFFICIENCY OF GROWING SWEET POTATO (IPOMOEA BATATAS L. [LAM.]) IN POLISH SOIL AND CLIMATE CONDITIONS
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Impact of Climate Change on Water Sources and River‐Floodplain Mixing in the Natural Wetland Floodplain of Biebrza River
PublicationThe origins of river and floodplain waters (groundwater, rainfall, and snowmelt) and their extent during overbank flow events strongly impact ecological processes such as denitrification and vegetation development. However, the long-term sensitivity of floodplain water signatures to climate change remains elusive. We examined how the integrated hydrological model HydroGeoSphere and the Hydraulic Mixing-Cell method could help us...
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Changes in conditions of acoustic wave propagation in the Gdansk deep as an effect of climate changes in the Baltic Sea region
PublicationThe article presents the results from a research project investigating acoustic climate changes in the Gdansk Deep based on data extending from 1902 to 2019. This part of the southern Gotland Basin, is rarely discussed in the scientific literature. The speed of sound in the seawater is a function of temperature, salinity, and depth. In such shallow sea as Baltic Sea, the impact of depth is not substantial. The other two factors...
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Shaping the City Responding to Climate Change – Concept of Development of the Right Bank of the Vistula River in Toruń, Poland,
PublicationThe problems of cities of the 21st century are caused by anthropogenic oppression of the environment, through the growth of economic activity and continuous urbanisation, and taking away ecologically important open areas and biologically active areas. Increasingly frequent and sudden rains, strong winds, turbulence and rising world water levels are some of the consequences of climate change that have a direct impact on the functioning...
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Extreme weather layer method for implementation of nature-based solutions for climate adaptation: Case study Słupsk
PublicationOne of the most severe climate risks that is expected to affect all regions is related to stormwater. Climate models, constructed based on long-term trends, show that extreme weather events such as storms, cloudbursts and a large rise in sea level will be significant in the coming decades. Moreover, even the frequency and intensity of “normal” rainfall events, such as microbursts, are expected to be remarkably higher than today...
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Smart and resilient cities- new challanges for Polish cities in terms of 2020 energy efficiency and climate action
PublicationGlobal climate change action along with energy efficiency optimizations are becoming increasingly pressing principles in terms of moving towards sustainable development. As a member of EU and UN Poland is also obliged to follow restricted rules concerning energy efficiency of buildings which come to force in 2020. To meet new goals, innovative approaches - like moving towards smart and resilient cities -may be required. Through...
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Uric acid and xantine-oxidase inhibitors in patients with gout: A re-assessment and an update
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Linear Pantographic Sheets: Existence and Uniqueness of Weak Solutions
Publicationwe address the well-posedness of the planar linearized equilibrium problem for homogenized pantographic lattices. To do so: (i) we introduce a class of subsets of anisotropic Sobolev’s space as the most suitable energy space E relative to assigned boundary conditions; (ii) we prove that the considered strain energy density is coercive and positive definite in E ; (iii) we prove that the set of placements for which the strain...
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Analysis of multi-class pharmaceuticals in fish tissues by ultra-high-performance liquid chromatography tandem mass spectrometry
PublicationA new sensitive method based on pressurized liquid extraction (PLE) and purification by gel permeation chromatography (GPC) prior to ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS) was developed for the determination in fish homogenate, liver and muscle of twenty pharmaceuticals compounds and metabolites from seven commonly used therapeutic families. An extensive matrix effect evaluation...
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Phosphorylation‐mediated regulation of heat shock response in Escherichia coli
PublicationEscherichia coli has two heat shock regulons under the transcriptional control of Esigma(32) and Esigma(E) RNA polymerases. These polymerases control the expression of genes, the products of which are needed for correct folding of proteins in the cytoplasm and the extracytoplasm respectively. In this study, we report that mutations in a tyrosine phosphatase-encoding gene led to decreased activity of these heat shock regulons. The...
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Variation de l’épaisseur du placage de déroulage des bois et son influence sur les caractéristiques mécaniques des panneaux LVL
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Meteorological study of the first observation of red sprites from Poland
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Method for Determination of Methyl tert-Butyl Ether and Its Degradation Products in Water
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Sense of Purpose in Life and Escape from Self as the Predictors of Quality of Life in Clinical Samples
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Suicidal thoughts in persons treated for alcohol dependence: The role of selected demographic and clinical factors
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Molecular characteristics of community-associated methicillin-resistant Staphylococcus aureus strains for clinical medicine
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Sperm Antioxidant Biomarkers and Their Correlation with Clinical Condition and Lifestyle with Regard to Male Reproductive Potential
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Preliminary studies on DNA retardation by MutS applied to the detection of point mutations in clinical samples
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A review of the traditional uses, phytochemistry, pharmacology, and clinical evidence for the use of the genus Alchemilla (Rosaceae)
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Documenting the de-identification process of clinical and imaging data for AI for health imaging projects
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Optimization of Novel Human Acellular Dermal Dressing Sterilization for Routine Use in Clinical Practice
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Incidence and Clinical Course of Respiratory Viral Coinfections in Children Aged 0–59 Months
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Retrospective liver histomorphological analysis in dogs in instances of clinical suspicion of congenital portosystemic shunt
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Test Your Memory (TYM) as a screening instrument in clinical practice – the Polish validation study
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Which Target Blood Pressure in Year 2018? Evidence from Recent Clinical Trials
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Clinical Training during the COVID-19 Pandemic: Experiences of Nursing Students and Implications for Education
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Adipocyte Fatty Acid‐Binding Protein as a Novel Marker of Psoriasis and Clinical Response to Acitretin
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Yoga for Heart Rate Variability: A Systematic Review and Meta-analysis of Randomized Clinical Trials
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Decisional DNA for modeling and reuse of experiential clinical assessments in breast cancer diagnosis and treatment
PublicationClinical Decision Support Systems (CDSS) are active knowledge resources that use patient data to generate case specific advice. The fast pace of change of clinical knowledge imposes to CDSS the continuous update of the domain knowledge and decision criteria. Traditional approaches require costly tedious manual maintenance of the CDSS knowledge bases and repositories. Often, such an effort cannot be assumed by medical teams, hence...
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New, fast and cheap prediction tests for BRCA1 gene mutations identification in clinical samples.
PublicationDespite significant progress in cancer therapy, cancer is still the second cause of mortality in the world. The necessity to make quick therapeutic decisions forces the development of procedures allowing to obtain a reliable result in a quick and unambiguous manner. Currently, detecting predictive mutations, including BRCA1, is the basis for effectively treating advanced breast cancer. Here, we present new insight on gene mutation...
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Is the Keros classification alone enough to identify patients with the ‘dangerous ethmoid’? An anatomical study
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Characterization and classification of hoarfrost samples collected in Poland (2003-2005) by discriminant analysis
PublicationTechnikę analizy dyskryminacyjnej wykorzystano do klasyfikacji próbek szronu (zebranych w latach 2003-2005 na terenie m.in. Gdańska, Grudziądza, Poznania) na naturalnie wyłaniające się grupy oraz by zidentyfikować parametry fizykochemiczne odpowiedzialne za podobieństwa i różnice pomiędzy poszczególnymi miejscami pobierania próbek. Aby ocenić jakość dyskryminacji zastosowano m.in. następujące kryteria: lambdę Wilksa, cząstkową...
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Segmentation-Based BI-RADS Ensemble Classification of Breast Tumours in Ultrasound Images
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Expert System as a classification method for optimal Legg-Calve-Perthes Disease treatment
PublicationZaproponowano utworzenie systemu eksperckiego jako metody klasyfikacji w prognozowaniu dowolnej formy leczenia dzieci z chorobą Legg-Calve-Perthesa. Obecnie nie ma jednego optymalnego sposobu leczenia choroby Perhtes'a i proponowana metoda jest próbą utworzenia wymiernego i uniwersalnego narzędzia, które będzie stanowiło podstawę przy podejmowaniu decyzji o najlepszym sposobie leczenia chorego stawu biodrowego. System ekspercki,...
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Leveraging Training Strategies of Artificial Neural Network for Classification of Multiday Electromyography Signals
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Multi-Label Classification for AIS Data Anomaly Detection Using Wavelet Transform
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Artificial Neural Networks in Classification of Steel Grades Based on Non-Destructive Tests
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Influence of accelerometer signal pre-processing and classification method on human activity recognition
PublicationA study of data pre-processing influence on accelerometer-based human activity recognition algorithms is presented. The frequency band used to filter-out the accelerometer signals and the number of accelerometers involved were considered in terms of their influence on the recognition accuracy. In the test four methods of classification were used: support vector machine, decision trees, neural network, k-nearest neighbor.
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Application of passive acoustic radar to automatic localization, tracking and classification of sound sources
PublicationA concept, practical realization and applications of the passive acoustic radar to automatic localization, tracking and classification of sound sources were presented in the paper. The device consists of a new kind of multichannel miniature sound intensity sensors and a group of digital signal processing algorithms. Contrary to active radars, it does not emit the scanning beam but after receiving surrounding sounds it provides...