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total: 906
Search results for: molecular medicine
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Efficient production of Staphylococcus simulans lysostaphin in a benchtop bioreactor by recombinant Escherichia coli.
PublicationLysostaphin is an enzyme with bactericidal activity against Staphylococcus aureus and other staphylococcal species. In spite of many advantages and promising results of preliminary research, the enzyme is still not widely used in medicine, veterinary or as a food preservative. One of the most important factors limiting application of the enzyme in clinical or technological practice is the high costs of its production. In the present...
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Multisine impedimetric probing of biocatalytic reactions for label-free detection of DEFB1 gene: How to verify that your dog is not human?
PublicationAlbert is a dog (Canis familiaris), but he does not realize this. Albert loves human food (and beer), watching movies on the internet, sleeping in bed, and more. But he should not do all these things. To convince him that, we have desinged a test procedure. The DEFB1 gene is unique to human species. Detecting its presence from saliva and in short periods may offer an advantage in the field of forensic medicine, and influence Albert’s...
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Discovery of small-molecule regenerative drugs using a model of complex tissue injury in mice. Transcriptomic responses of neurodevelopmental genes during pharmacologically induced regeneration
PublicationDespite significant development in regenerative medicine, there is a deficit of effective therapies for wound healing and tissue regeneration. Research performed using animal wound models allows for a better understanding of this complex process, searching for compounds with pro-regenerative properties, and assessing their efficacy and safety. Unfortunately, the lack of adequate preclinical models proves to be an issue as no animal...
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Wykorzystanie kamery termowizyjnej nowej generacji do oceny wpływu sił ortodontycznych na dziąsło = The application of a new-generation thermal imaging camera for the assessment of hemodynamic changes in gingiva during orthodontic treatment
PublicationIntroduction. One ot the most interesting modern methods of assessing microcirculation is thermovisiual examination. Thermovision cameras are commonly used in general medicine. As the periodontium is one of the most vascularized tissues in the human body, the application of high-sensitivity thermovision cameras may allow tor noninvasive asses- sment and early detection ot pathological changes in the gingiva by giving a complete...
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Preparation and properties of composite coatings, based on carbon nanotubes, for medical applications
PublicationThe coatings based on carbon nanotubes (CNTs) are increasingly developed for their applications, among others, in medicine, in particular for implants in implantology, cardiology, and neurology. The present review paper aims at a detailed demonstration of diferent preparation methods for such coatings, their performance, and relationships between deposition parameters and microstructure and material, mechanical, physical, chemical,...
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Comparative Analysis of Phytochemical Profiles and Selected Biological Activities of Various Morphological Parts of Ligustrum vulgare
PublicationLigustrum vulgare (LV), widely cultivated in Europe and often used in hedges, has been histori-cally recognized in folk medicine for its potential health benefits. This study focused on exploring the untargeted identification of secondary metabolites in ethanol extracts (70% v/v) from differ-ent morphological parts (young shoots, leaves, flowers and fruits) of LV at various stages of plant development, using ultra-high-performance...
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Whether Carbon Nanotubes Are Capable, Promising, and Safe for Their Application in Nervous System Regeneration. Some Critical Remarks and Research Strategies
PublicationCarbon nanotubes are applied in or considered for different fields of medicine. Among them is the regeneration or rebuilding of nervous system components, which still lack substantial progress; this field is supported by carbon nanotubes to a great extent as the principal material. The limited research on this issue has involved PU/silk/MWCNTs, PCL/silk/MWCNTs, PCL/PGS/CNTs, chitin/CNTs, PGF/CNTs, CNTs/PGFs/PLDLA,MWCNTs chitosan,MWCNTs/PPy,...
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Expert System and Decision Support System for Electrocardiogram Interpretation and Diagnosis: Review, Challenges and Research Directions
PublicationElectrocardiography (ECG) is one of the most widely used recordings in clinical medicine. ECG deals with the recording of electrical activity that is generated by the heart through the surface of the body. The electrical activity generated by the heart is measured using electrodes that are attached to the body surface. The use of ECG in the diagnosis and management of cardiovascular disease (CVD) has been in existence for over...
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ChatGPT Application vis-a-vis Open Government Data (OGD): Capabilities, Public Values, Issues and a Research Agenda
PublicationAs a novel Artificial Intelligence (AI) application, ChatGPT holds pertinence not only for the academic, medicine, law, computing or other sectors, but also for the public sector-case in point being the Open Government Data (OGD) initiative. However, though there has been some limited (as this topic is quite new) research concerning the capabilities ChatGPT in these sectors, there has been no research about the capabilities it...
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Real-time facial feature tracking in poor quality thermal imagery
PublicationRecently, facial feature tracking systems have become more and more popular because of many possible use cases. Especially in medical applications location of the face and facial features are very useful. Many researches have presented methods to detect and track facial features in visible light. However, facial feature analysis in thermography may also be very advantageous. Some examples of using infrared imagery in medicine include...
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Canned food as a source of bisphenol a (BPA) exposure - estimation of consumption among young women from Gdansk, Poland
PublicationBisfenol A (BPA) jest organicznym związkiem endokrynnie czynnym , który modyfikuje pracę hormonów prowadząc do niekorzystnych dla zdrowia skutków. BPA jest substancją stabilizującą chlorek poliwinylu- jednego z najczęściej stosowanych polimerów plastików, wykorzystywanego w produkcji powszechnie używanych produktów, w tym opakowań, plastikowych butelek, zabawek, papieru paragonowego; używany jest także w produkcji żywic epoksydowych...
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Three-dimensional printed trachea helps to design tailored treatment for tracheobronchomalacia
PublicationTracheobronchomalacia is a rare respiratory disease that is manifesting by impaired ventilation with expiratory collapse of the tracheal wall due to softening of the supporting cartilage and hypotonia of myoelastic elements [1]. Surgery is the mainstay of treatment. We report the case of 39 -year old man with exacerbation of chronic respiratory distress. The membranous wall of the trachea and the large bronchi was stretched to...
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Influence of Diosmin Treatment on the Level of Oxidative Stress Markers in Patients with Chronic Venous Insufficiency
PublicationOxidative stress plays an important role in the pathophysiology of many human disorders, while antioxidants prevent the development of various adverse symptoms. Diosmin is a natural flavonoid applied in vascular system disorders, especially in chronic venous insufficiency (CVI), and it plays a significant part in the alleviation of CVI symptoms. Due to antioxidant activity, it also has the ability to scavenge the oxygen free radicals...
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Coupling of Blood Pressure and Subarachnoid Space Oscillations at Cardiac Frequency Evoked by Handgrip and Cold Tests: A Bispectral Analysis
PublicationThe aim of the study was to assess blood pressure–subarachnoid space (BP–SAS) width coupling properties using time–frequency bispectral analysis based on wavelet transforms during handgrip and cold tests. The experiments were performed on a group of 16 healthy subjects (F/M; 7/9) of the mean age 27.2 ± 6.8 years and body mass index of 23.8 ± 4.1 kg/m². The sequence of challenges was first handgrip and then cold test. The handgrip...
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Lipid peroxidation in the onset of neuroborreliosis
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Liver antioxidant defense after FAAH inhibitor - URB-597 administration to DOCA-salt-induced hypertension in rats
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The cross-talk between oxidative stress and endocannabinoid system in keratinocytes after UV irradiation
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Tick-borne encephalitis - lipid peroxidation and its consequences
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Antioxidants and HNE in redox homeostasis
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Peroxidative metabolism of arachidonic acid in the course of Lyme arthritis
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Peroxidative metabolism of fatty acids in the course of tick-borne encephalitis
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The cross talk between redox and endocannabinoids systems in the kidney of hypertensive rats after inhibitor FAAH - URB597 administration
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Antioxidants and HNE in the regulation of redox homeostasis
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Lipid peroxidation as a consequence of diabetes: effects of different treatment
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Lipid peroxidation in the pathogenesis of neuroborreliosis
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Percutaneous Tracheostomy
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Combining markers of nephrotoxicity and hepatotoxicity for improved monitoring and detection of chronic alcohol abuse
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Nucleotide excision repair of oxidised genomic DNA is not a source of urinary 8-oxo-7,8-dihydro-2′-deoxyguanosine
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Supplementation with antioxidant vitamins prevents oxidative modification of DNA in lymphocytes of HIV-infected patients
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Further evidence that oxidative stress may be a risk factor responsible for the development of atherosclerosis
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Aberrant repair of etheno–DNA adducts in leukocytes and colon tissue of colon cancer patients
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Vitamin C enhances substantially formation of 5-hydroxymethyluracil in cellular DNA
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Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome1 1This article is part of a series of reviews on “Oxidative DNA Damage and Repair.” The full list of papers may be found on the homepage of the journal.
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ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation
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Forms of expressing anger in hospitalised Ukrainian post-deployed™ service members
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The influence of 9-day trekking in the Alps on the level of oxidative stress parameters and blood parameters in native lowlanders
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Comparison of post-mortem ethanol level in blood and bone marrow
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Nonfatal and fatal intoxications with pure caffeine – report of three different cases
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Life style and cardiovascular risk factors among students of Wroclaw postgraduate schools
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Acute intranasal intoxication with mercuric chloride taken accidently instead of cocaine - A case report
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Remdesivir-based therapy improved recovery of patients with COVID-19 in the SARSTer multicentre, real-world study
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Levels of hemoglobin and lipid peroxidation metabolites in blood, catalase activity in erythrocytes and peak expiratory flow rate in subjects with passive exposure to tobacco smoke
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Evaluating the Hearing of Patients with Pseudoexfoliation Syndrome
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Pain assessment and management in children in the postoperative period: A review of the most commonly used postoperative pain assessment tools, new diagnostic methods and the latest guidelines for postoperative pain therapy in children
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Association between small fiber neuropathy and higher skin accumulation of advanced glycation end products in patients with type 1 diabetes
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Impact of heavy metals on the female reproductive system
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Chosen single nucleotide polymorphisms (SNPs) of enamel formation genes and dental caries in a population of Polish children
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Technical aspects of nasal cavity surgery through the Le Fort I down-fracture approach: An otolaryngologist’s point of view based on 90 patients’ experience
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Optical coherence tomography and magnetic resonance imaging visual pathway evaluation in Wolfram syndrome
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Preventive Effect of Lithium on “Kleine–Levin Syndrome”
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