Search
Filters
total: 466
filtered: 388
Search results for: CYANIDE TOXICITY
-
Chemometric estimation of natural water and sediment using toxicity tests and physicochemical parameters
PublicationOceny jakości wód dokonano na podstawie analizy chemometrycznej bazy danych monitoringowych, składającej się z wyników testów toksyczności i wyników badań parametrów fizykochemicznych. Badaniom poddano próbki wód powierzchniowych pobrane z Jeziora Turawskiego oraz próbki wód podziemnych pobranych z otworów badawczych wykonanych w jego dnie, jak i wokół niego. Zastosowano następujące metody chemometryczne: analizę wiązkową i analizę...
-
Organic micropollutants paracetamol and ibuprofen—toxicity, biodegradation, and genetic background of their utilization by bacteria
Publication -
Mitochondria dysfunction is one of the causes of diclofenac toxicity in the green alga Chlamydomonas reinhardtii
Publication -
<p>Analysis of toxicity and anticancer activity of micelles of sodium alginate-curcumin</p>
Publication -
Toxicity of sediments and its relations with the mobility of pollutants on the basis of studies of Lake Turawskie
PublicationPraca niniejsza jest raportem z badań nad toksycznością i jej powiązaniem z mobilnością zanieczyszczeń. Moblilność zanieczyszczeń uzależniona jest od pH próbki. Próbki pobierano z Jez. Turawskiego, toksyczność była mierzona przy użyciu testu Microtox (AZUR Environmental, USA).
-
Organomercury compounds in environmental samples: emission sources, toxicity, environmental fate and determination.
PublicationIn view of the specific properties of mercury and its capability of forming compounds that can be bioaccumulated and biomagnified at successive levels of the trophic pyramid, it has become necessary to gather detailed information on the sources of emission of this element into the environment and its fate there. Moreover, the increasing awareness of the relationship between the toxicity of mercury and its chemical form has sharpened...
-
Detrimental effects of chemotherapeutics and other drugs on the endothelium: A call for endothelial toxicity profiling
Publication -
Selected issues related to the toxicity of ionic liquids and deep eutectic solvents—a review
PublicationGreen Chemistry plays a more and more important role in implementing rules of sustainable development to prevent environmental pollution caused by technological processes, while simultaneously increasing the production yield. Ionic liquids (ILs) and deep eutectic solvents (DESs) constitute a very broad group of substances. Apart from many imperfections, ILs and DESs have been the most promising discoveries in the world of Green...
-
Modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models
PublicationThe present study deals with assessment of ecotoxicological parameters of 9 drugs (diclofenac (sodium salt), oxytetracycline hydrochloride, fluoxetine hydrochloride, chloramphenicol, ketoprofen, progesterone, estrone, androstenedione and gemfibrozil), present in the environmental compartments at specific concentration levels, and theirmutual combinations by couples against Microtox® and XenoScreen YES/YAS® bioassays. As the quantitative...
-
Assessing Acute Toxicity of Selected Packages Internal Layers Extracts using Microtox®
PublicationIn the scientific literature related to the widely understood issue of packaging materials designed to have contact with food (food contact materials), there is much information on raw materials used for their production, as well as their physiochemical properties, types and parameters. Unfortunately, not much attention is given to the issues concerning migration of toxic substances from packaging and its actual influence on the...
-
Electroporation and lipid nanoparticles with cyanine IR-780 and flavonoids as efficient vectors to enhanced drug delivery in colon cancer
Publication -
Tuning of the phase transition between site selective SCO and intermetallic ET in trimetallic magnetic cyanido-bridged clusters
Publication -
A heterotrimetallic synthetic approach in versatile functionalization of nanosized {MxCu13–xW7}3+ and {M1Cu8W6} (M = Co, Ni, Mn, Fe) metal–cyanide magnetic clusters
Publication -
High Signal Resolution Pulse Oximetry as a Prognostic Indicator of Radiotherapy Toxicity: A Pilot Study
PublicationIntroduction: Radiotherapy plays a prominent role in the multidisciplinary treatment of cancers. Despite new irradiation techniques, radiation-induced cardiotoxicity remains a leading cause of morbidity and mortality. Therefore, prognostic indicators of radiotherapy toxicity are essential. This study aimed to investigate the influence of applied radiotherapy on the pulse wave recording and thereby on...
-
Mathematical Modelling and Effect Size Analysis in Support of Searching for the Proteomic Signature of Radiotherapy Toxicity
Publication -
In Vivo Efficacy, Toxicity Assessment, and Elemental Analysis of Traditionally Used Polyherbal Recipe for Diarrhea
Publication -
ALLEVIATING EFFECTS OF ASCORBIC ACID ON LEAD TOXICITY IN GOJI (Lycium barbarum L.) IN VITRO
Publication -
Toxicity assessment of sediments associated with the wreck of s/s Stuttgart in the Gulf of Gdańsk (Poland)
PublicationPrzeprowadzono badania w pobliżu wraku s/s Stuttgart zalegającego przy Polskim wybrzeżu (Zatoka Gdańska) i stanowiącego źródło zanieczyszczenia w formie WWA i PCB. Przeprowadzono oznaczenia śladowych zanieczyszczeń organicznych oraz badania toksykologiczne aby oszacować ryzyko ze strony wraku i jego pozostałości. W wyniku badań można stwierdzić, że tylko siły grawitacyjne i kształt dna morskiego są czynnikami wpływającymi na transport...
-
Environmental transformation and nano-toxicity of engineered nano-particles (ENPs) in aquatic and terrestrial organisms
Publication -
Analytical aspects of model compounds toxicity assessment using MTT and Microtox bioanalytica assays
PublicationMore and more increased intensity of anthropopressure processes can be observed, among other things, in the release of great quantities of synthetic substances into the environment, including the Endocrine Disrupting Compounds. The effects of the above-mentioned human impact on the environment not only can be noticed in the homeostasis disturbance in ecosystems, but they are also visible with respect to human. The high incidence...
-
The Substantial Improvement of Amphotericin B Selective Toxicity Upon Modification of Mycosamine with Bulky Substituents
PublicationAbstract: Background: It is assumed that the unfavorable selective toxicity of an antifungal drug Amphotericin B (AmB) can be improved upon chemical modification of the antibiotic molecule. Objective: The aim of this study was verification of the hypothesis that introduction of bulky substituents at the amino sugar moiety of the antibiotic may result in diminishment of mammalian vitro toxicity of thus prepared AmB derivatives. Methods:...
-
Application of BiOClnBrm photocatalyst to cytostatic drugs removal from water; mechanism and toxicity assessment
PublicationThe photocatalytic activity of series of BiOClnBrm photocatalysts toward degradation and mineralization of the cytostatic drugs 5-fluorouracil (5-FU) and imatinib mesylate (IMA) both singly and in their mixture under simulated solar and visible light irradiation has been investigated. Screening test revealed that among BiOClnBrm photocatalysts synthesized by a solvothermal method, the one with molar 1.3Cl/0.7Br ratio was the most...
-
Assessing Acute Toxicity and Endocrine Disruption Potential of Selected Packages Internal Layers Extracts
PublicationThe focus of the present study is migration of toxic substances from food contact materials and its actual influence on the health of the final consumer. Two food packagings (metal cans, TetraPack®) and five simulants medias (water, ethanol, acetic acid, DMSO, artificial saliva) were selected for simulation studies. For assessment of acute toxicity and endocrine disruption potential of extract samples, two biotests (Microtox® and...
-
Application of chemometric techniques in studies of toxicity of selected commercially available products for infants and children
PublicationThe goal of the present study is to assess the impact of the experimental conditions for extraction procedures (time of extraction, thermal treatment and type of extraction media) as applied to several baby and infant products checked for their possible ecotoxicological response when tested by various ecotoxicity tests(Microtox®, Ostracodtoxkit F™and Xenoscreen YES/YAS™). The systems under consideration are multidimensional by...
-
The in vitro culture supplements and selected aspects of canine oocytes maturation
Publication -
Spillover Effect Occurrence in Tricity
PublicationThe key topic of this paper is a spillover effect from multinational companies to the local business environment in Tricity. The purpose of the research is to examine whether spillover effect is present in Tricity, to what extent, and, more importantly, what should be the reaction of the local authorities to the results. Based on qualitative interview-based research conducted with the multinational corporations’ employees, spillover...
-
Deep eutectic solvents microbial toxicity: Current state of art and critical evaluation of testing methods
PublicationDeep eutectic solvents (DESs) were described at the beginning of 21st century and they consist of a mixture of two or more solid components, which gives rise to a lower melting point compared to the starting materials. Over the years, DESs have proved to be a promising alternative to traditional organic solvents and ionic liquids (ILs) due to their low volatility, low inflammability, easy preparation, and usually low cost of compounds...
-
Acute and subacute (28-Day) toxicity studies of ionic liquid, didecyldimethyl ammonium acesulfamate, in rats
Publication -
Toxicity of aqueous mixture of phenol and chlorophenols upon photosensitized oxidation initiated by sunlight or vis-lamp
Publication -
Comparison between industrial and simulated textile wastewater treatment by AOPs – Biodegradability, toxicity and cost assessment
Publication -
Renoprotective and Cardioprotective Potential of Moricandia sinaica (Boiss.) against Carbon Tetrachloride-Induced Toxicity in Rats
Publication -
Enzymatic assays confirm the toxicity reduction after manure treatment of heavy metals contaminated soil
Publication -
Cadmium-Induced Oxidative Stress in Plants, Cadmium Toxicity, and Tolerance in Plants: From Physiology to Remediation
Publication -
Interactions of amphotericin B derivative of low toxicity with biological membrane components - the Langmuir monolayer approach
PublicationMetodą monowarstw Langmuira zbadano naturę oddziaływań nowej pochodnej antybiotyku przeciwgrzybowego amfoterycyny B o niskiej toksyczności, tj. estru metylowego N-metylo-N-D-fruktopiranozyloamfoterycyny B (MF-AME)z komponentami błon biologicznych: ergosterolem, występującym w komórkach grzybowych i cholesterolem występującym w komórkach zwierzęcych oraz z modelowym fosfolipidem DPPC i na tej podstawie stwierdzono, że zróżnicowanie...
-
Impact of inorganic ions and pH variations on toxicity and endocrine potential of selected environmentally relevant pharmaceuticals
PublicationAssessment of the impact of pharmaceutical residues on living organisms is a very complex subject. Apart from taking into account the toxicity of individual compounds, environmental factors should also be taken into account. In this paper, attempts were made to assess the impact of coexisting inorganic ions and changes in pH on the toxicity of ten selected pharmaceuticals. Two bioassays were used to measure the estrogenic and androgenic...
-
Role of size scale of ZnO nanoparticles and microparticles on toxicity toward bacteria and osteoblast cancer cells
PublicationThe specific role of size scale, surface capping, and aspect ratio of zinc oxide (ZnO) particles on toxicity toward prokaryotic and eukaryotic cells was investigated. ZnO nano and microparticles of controlled size and mor- phology were synthesized by wet chemical methods. Cytotoxicity toward mammalian cells was studied using a human osteoblast cancer cell line and antibacterial activity using Gram-negative bacteria (Escherichia...
-
Modeling and MANOVA studies on toxicity and endocrine potential of packaging materials exposed to different extraction schemes
PublicationThe stability of the linings of packaging that is in contact with the goods stored has been of major concern during decades of the development of packaging materials. In this work, an attempt was undertaken to assess the applicability of using two bioassays (Microtox® and XenoScreen YES/YAS) in estimating the stability of packaging (cans, caps, multilayer material) and the impact of their degradation on the toxicity of some simulated media....
-
ELECTROCHEMOTHERAPY COMBINED WITH STANDARD AND CO2 LASER SURGERIES IN CANINE ORAL MELANOMA
Publication -
The immunological, biochemical and molecular bases of canine senescence and carcinogenesis: a review
Publication -
Defect in Mitochondrial NADH-Dehydrogenase Genes in Canine Mast Cell Tumours
Publication -
Modified Ventral Femoral Head and Neck Ostectomy: A Canine Cadaver Study
Publication -
Monitoring of odour nuisance in the Tricity Agglomeration
PublicationThe paper describes a principle of operation of odour nuisance monitoring network, which is being designed in the Tricity Agglomeration. Moreover, it presents the preliminary results of an investigation on ambient air quality with respect to odour nuisance in a vicinity of the municipal landfill. The investigation was performed during spring-winter season using a prototype of electronic nose and the Nasal Ranger field olfactometers. The...
-
Enhanced Toxicity of Bisphenols Together with UV Filters in Water: Identification of Synergy and Antagonism in Three-Component Mixtures
PublicationContaminants of emerging concern (CEC) localize in the biome in variable combinations of complex mixtures that are often environmentally persistent, bioaccumulate and biomagnify, prompting a need for extensive monitoring. Many cosmetics include UV filters that are listed as CECs, such as benzophenone derivatives (oxybenzone, OXYB), cinnamates (2-ethylhexyl 4-methoxycinnamate, EMC) and camphor derivatives (4-methylbenzylidene-camphor,...
-
Soil pH effects on the comparative toxicity of dissolved zinc, non-nano and nano ZnO to the earthwormEisenia fetida
Publication -
The chemistry and toxicity of discharge waters from copper mine tailing impoundment in the valley of the Apuseni Mountains in Romania
Publication -
Comparison of radical-driven technologies applied for paraben mixture degradation: mechanism, biodegradability, toxicity and cost assessment
Publication -
DNA adduct formation by C-1748, a potent antitumor 4-methyl-1-nitroacridine of lowered toxicity.
Publication4-podstawione 1-nitroakrydyny reprezentują nową grupę pochodnych zsyntetyzowanych na Politechnice Gdańskiej. W porównaniu do macierzystych 1-nitroakrydyn związki te wykazują obniżoną toksyczność i podwyższoną aktywność przeciwnowotworową. Wiodąca pochodna 4-metylo-1-nitroakrydyna o symbolu C-1748 jest obecnie w przygotowaniu do I fazy badań klinicznych w leczeniu raka okrężnicy. Wprowadzenie elektrodonorowej grupy metylowej w...
-
Toxicity Assessment by Microtox® in Sediments, Pore Waters and Sediment Saline Elutriates in the Gulf of Gdansk (Baltic Sea)
Publication -
The Interaction of Heptakis (2,6-di-O-Methyl)-β-Cyclodextrin with Mianserin Hydrochloride and Its Influence on the Drug Toxicity
PublicationOne tetracyclic antidepressant, mianserin hydrochloride (MIA), has quite significant side effects on a patients’ health. Cyclodextrins, which are most commonly used to reduce the undesirable features of contained drugs within their hydrophobic interior, also have the potential to alter the toxic behavior of the drug. The present paper contains investigations and the characteristics of interaction mechanisms for MIA and the heptakis...
-
Quest for the Molecular Basis of Improved Selective Toxicity of All-Trans Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics
PublicationThree aromatic heptaene macrolide antifungal antibiotics, Candicidin D, Partricin A (Gedamycin) and Partricin B (Vacidin) were subjected to controlled cis-trans to all trans photochemical isomerization. The obtained all-trans isomers demonstrated substantially improved in vitro selective toxicity in the Candida albicans cells: human erythrocytes model. This effect was mainly due to the diminished hemotoxicity. The molecular modeling...