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Search results for: THYROID FUNCTION
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Potential of Liquid Biopsy in Papillary Thyroid Carcinoma in Context of miRNA, BRAF and p53 Mutation
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Evaluation and cellular responses of modulators of TRF1/TRF2 protein’s function as potential anticancer drugs interfering with telomeric shelterin’s function
PublicationA number of proteins that interact with telomeres have been identified in human cells, indicating the high plasticity of human nucleoprotein complex organization. The most important complex is the "shelterin" complex, which consists of six proteins: TRF1, TRF2, TIN2, POT1, TPP1. The TRF1 and TRF2 directly bind to telomeric double-stranded DNA and the TIN2 protein. The TIN2 protein also binds to the TPP1 protein, stabilizing the...
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Classification of Thyroid Tumors Based on Mass Spectrometry Imaging of Tissue Microarrays; a Single-Pixel Approach
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Biochemical properties of thyroid peroxidase (TPO) expressed in human breast and mammary-derived cell lines
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Resolving the role of podoplanin in the motility of papillary thyroid carcinoma-derived cells using RNA sequencing
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Security level estimation as a function of residual risks
PublicationArtykuł przedstawia sposób oceny poziomu bezpieczeństwa organizacji IT w oparciu o metodę oceny ryzyka. Opisane są podstawowe kroki wspomnianej metody, proponowane rozwiązania i zastosowania. Zaproponowano prosty sposób oceny bezpieczeństwa systemów informatycznych organizacji w oparciu o wielkość wyznaczoną na podstawie wyliczonego ryzyka rezydualnego tychże systemów.
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Country Safety Performance Function and the factors affecting it
PublicationW artykule przedstawiono metodę modelowania wpływu wybranych czynników na liczbę ofiar śmiertelnych na poziomie światowym. Do budowy modeli wykorzystano podejście bazujące na ryzyku. Wykorzystano dane z kilkudziesięciu krajów świata.
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MutS3: a MutS homologue of unknown biological function
PublicationThe homologues of MutS proteins are widespread among both Prokaryotes and Eukaryotes. MutS designated as MutS1 is a part of MMR (mismatch repair) system which is responsible for removal of mispaired bases and small insertion/deletion loops in DNA. Initially, the only MutS homologues known were those engaged in mismatch repair and these were later designated as MutS1. Subsequently, the MutS2 homologue was distinguished. MutS2 does...
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Green function diagonal for a class of heat equations
PublicationA construction of the heat kernel diagonal is considered as element of generalized zeta function theory, which gradient at the origin defines determinant of a differential operator in a technique for regularizing quadratic path integral. Some classes of explicit expressions of the Green function in the case of finite-gap potential coefficient of the heat equation are constructed. An algorithm and program for Mathematica are presented...
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Clothing sets with thermoregulation function for mine rescuers
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RSN reverse converter based on core function
Publicationzaprezentowano nową architekturę konwertera z systemu resztowego do systemu binarnego opartego na funkcji jądra dla modułów 5-bitowego. Zastosowano niekrytyczną funkcję jądra.Obliczanie funkcji jądra jest realizowane przy użyciu chińskiego twierdzenia dla funkcji jądra (CRTCF). Założono także, że jeden z modułów jest potegą 2. Architektura ta umożliwia zmniejszenie złożoności sprzętowej o ok. 12.5% w porównaniu z innymi architekturami...
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The productive function of the will in the pfilosophical thought of William James
PublicationW artykule przedstawiłem W. Jamesa koncepcję wolnej woli w jej wytwórczej funkcji. Pokazałem, że zrównuje ona ludzkie poznanie i ludzką aktywność. Następnie podkreśliłem, że wola ma wieloaspektowy charakter w formowaniu nowego "wewnętrznego człowieka". W związku z tym, zanalizowałem tzw. empiryczne 'ja' jako "niższe" i "wyższe" 'ja'. Z kolei podkreśliłem walor konsekwencji teleologicznej cechy ludzkiej...
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Firing map of an almost periodic input function
PublicationIn mathematical biology and the theory of electric networks the firing map of an integrate-and-fire system is a notion of importance. In order to prove useful properties of this map authors of previous papers assumed that the stimulus function f of the system ẋ = f(t,x) is continuous and usually periodic in the time variable. In this work we show that the required properties of the firing map for the simplified model ẋ = f(t) still...
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THE FUNCTION OF GREENERY IN A SKYSCRAPER: THE PLACEMENT AND ITS INFLUENCE
PublicationThe contrast between the high rise buildings; with their mostly geometric shapes, and the organic form of the greenery was visible even in the idea of a skyscraper. Yet the realizations and recent projects show emerging interest and the link between them. To better understand the developing function of the greenery in the context of a skyscraper, both literature and case studies are conducted. The aim is to relate the location...
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Approximation of Covariance Function with Application to Stochastic Mechanics.
PublicationW pracy przedstawiono koncepcję rozwinięć kanonicznych dla funkcji losowych oraz możliwość ich zastosowania w stochastycznej mechanice gruntów. Rozpatrzono rozkład widmowy, rozwinięcia Karhunena-Loevego oraz rozwinięcia ortogonalne zmodyfikowanymi wielomianami Hermite'a. Przeprowadzono analizę błędów dla zagadnienia warstwy gruntu o losowych parametrach sprężystych, uzyskano analityczne rozwiązanie systemu stochastycznego.
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Molecular profiles of thyroid cancer subtypes: Classification based on features of tissue revealed by mass spectrometry imaging
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Analysis of Let-7 Family miRNA in Plasma as Potential Predictive Biomarkers of Diagnosis for Papillary Thyroid Cancer
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Nicotinamide phosphorybosiltransferase overexpression in thyroid malignancies and its correlation with tumor stage and with survivin/survivin DEx3 expression
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On parameter derivatives of the associated Legendre function of the first kind (with applications to the construction of the associated Legendre function of the second kind of integer degree and order)
PublicationZnaleziono cztery nowe wyrażenia dla pochodnej stowarzyszonej funkcji Legendre'a pierwszego rodzaju względem jej stopnia w przypadku, gdy rząd i stopień są liczbami naturalnymi. Wyniki wykorzystano do podania nowych wyrażeń dla stowarzyszonych funkcji Legendre'a drugiego rodzaju z naturalnymi rzędem i stopniem.
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Automatic recognition of the arterial input function in MRI studies
PublicationArtykuł prezentuje opis automatycznej metody detekcji tętniczej funkcji wejście (AIF). Metoda została porównana z klinicznie pomierzonymi seriami obrazów DSC-MRI.
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BEHAVIOUR OF TiO2/CHITOSAN DISPERSION AS A FUNCTION OF SOLUTION pH
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Hybridization of the FDTD method with use of the discrete Green's function
PublicationIn this contribution, a hybrid technique is presented which combines the finite-difference time-domain (FDTD) method and the discrete Green's function (DGF) formulation of this method. FDTD is a powerful technique for the analysis of complex penetrable objects but its application is not efficient when the computational domain includes many free-space cells. Therefore, the hybrid method was developed which is applicable to complex...
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ISSUES OF CLASSIFICATION FUNCTION CONTINUITY IN ENDOSCOPIC VIDEO CLASSIFICATION
PublicationIn the article a new way of analyzing the properties of feature vector functions (FVF) and classiers of images in a video stream is proposed. The general idea is based on focusing of the perceived continuity of the FVF and classier functions. Issues related to creating an exact mathematical model are discussed and a simplied solution is proposed. An exemplary algorithm is evaluated on three exemplary video sequences. The acquired...
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Windowing of the Discrete Green's Function for Accurate FDTD Computations
PublicationThe paper presents systematic evaluation of the applicability of parametric and nonparametric window functions for truncation of the discrete Green's function (DGF). This function is directly derived from the FDTD update equations, thus the FDTD method and its integral discrete formulation can be perfectly coupled using DGF. Unfortunately, the DGF computations require processor time, hence DGF has to be truncated with appropriate...
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Accuracy of the Discrete Green's Function Formulation of the FDTD Method
PublicationThis paper reports an evaluation of the accuracy of the discrete Greens function (DGF) formulation of the finite-difference time-domain (FDTD) method. Recently, the closed-form expression for the DGF and its efficient numerical implementation were presented, which facilitates applications of the DGF in FDTD simulations of radiation and scattering problems. So far, the accuracy of the DGF formulation of the FDTD method has been...
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Residue-to-two's complement converter based on core function
PublicationW artykule przedstawiono układową realizację konwertera z systemu resztowego do systemu binarnego bazującego na funkcji jądra. Zastosowanie funkcji jądra powoduje zmniejszenie wymagań sprzętowych przy realizacji konwertera. W publikacji omówiono problem dektekcji znaku oraz realizacje ukłądową konwertera w środowisku FPGA.
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Studies on Function of P-Glycoprotein in Photodynamic Therapy of Endometriosis
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Port-based approach to distributed transfer function method
PublicationIn the paper there is presented an uniform, port-based approach to modeling of both lumped and distributed parameter systems. Port-based model of distributed system has been defined by application of distributed transfer function method (DTFM). The approach proposed combines versatility of port - based modeling and accuracy of distributed transfer function method. It enables to formulate appropriate input data for computer analysis...
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Regulation of Plant Microprocessor Function in Shaping microRNA Landscape
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A concept of a decision function discovery method in a workflow system
PublicationW pracy przedstawiono koncepcyjny model wykrywania zalezności funkcynnych pomiedzy elementami systemu przepływu pracy.
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Influence of transport policy on shape and function of public space
PublicationIstotnym wyznacznikiem atrakcyjności miejsca jest dostępność, zdeterminowana przez skalę podażowej polityki transportowej oraz wielkość wskaźnika motoryzacji. Samochód, jako dobro powszechnie dostępne, wpłyną na zmianę zachowań społecznych mieszkańców oraz na percepcję, kształt i funkcjonowanie przestrzeni miejskich. Z jednej strony integruje tkankę miejską, a z drugiej okupując wolne przestrzenie, nie uwzględniając żadnych wyższych...
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Green's function for the wavized Maxwell fish-eye problem
PublicationRozpatrzono niezależne od czasu skalarne równanie falowe dla ośrodka typu ''rybie oko'' Maxwella w przestrzeni R^N (N >=2). Pokazano, że równanie to posiada unikalne własności transformacyjne względem inwersji w pewnej klasie hipersfer. Wykorzystano ten fakt do znalezienia zamkniętej postaci funkcji Greena, oraz uogólnionej funkcji Greena, dla wyjściowego równania.
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Testing the durability and function of road traffic management devices
PublicationTraffic management measures (vertical signs and horizontal marking, reflective elements) are used for guiding vehicles optically, indicating road mileage, marking objects in road gauge, marking vehicle and pedestrian safeguards and driver information and warning. This paper presents a synthesis of a literature study and the results of research conducted under stage one of the project LifeRoSE. The requirements for different traffic...
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Integrate-and-fire models with an almost periodic input function
PublicationWe investigate leaky integrate-and-fire models (LIF models for short) driven by Stepanov and μ-almost periodic functions. Special attention is paid to the properties of the firing map and its displacement, which give information about the spiking behavior of the considered system. We provide conditions under which such maps are well-defined and are uniformly continuous. We show that the LIF models with Stepanov almost periodic...
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How to fund an additional secular function in the monumental church?
PublicationThe implementation of a new public function into the non-used church spaces like attics or cellars in context of revitalizing a lawfully protected historical city areas have diversified aspects. The article describes the financial aspect of adaptation of omitted spaces of monumental sacral buildings by presenting funding possibilities in the European Union countries available in period of 2017-2018 and the funds planned for the...
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Local basis function estimators for identification of nonstationary systems
PublicationThe problem of identification of a nonstationary stochastic system is considered and solved using local basis function approximation of system parameter trajectories. Unlike the classical basis function approach, which yields parameter estimates in the entire analysis interval, the proposed new identification procedure is operated in a sliding window mode and provides a sequence of point (rather than interval) estimates. It is...
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Local basis function method for identification of nonstationary systems
PublicationThis thesis is focused on the basis function method for the identification of nonstationary processes. The first chapter describes a group of models that can be identified using the basis function method. The next chapter describes the basic version of the basis function method, including its algebraic and statistical properties. The following section introduces the local basis function (LBF) method: its properties are described...
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The function and structure of entrance examination on faculty of architecture in Poland.
PublicationArtykuł prezentuje zastosowanie aksonometrii do oceny wyobraźni przestrzennej i pośrednio do selekcji kandydatów na Wydział Architektury. Na przykładzie kilku oryginalnych zadań wskazuje się na potrzebę prowadzenia ciągłej kontroli jakości zadań testowych. Jakościowe i ilościowe procedury służące do oceny zadań bazują na teorii pomiaru dydaktycznego i koncentrują się potwierdzeniu odpowiedniego poziomu rzetelności, trafności i...
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Survivability function - a measure of disaster-based routing performance.
PublicationZnaczenie przeżywalności sieci transmisji danych systematycznie rośnie, ponieważ awaria pojedynczego elementu może dotknąć miliony użytkowników na dużym obszarze. Zdefiniowano funkcję przeżywalności: prawdopodobieństwo realizacji określonego procentu strumieni użytkowników po awarii oraz atrybuty przeżywalności. Celem pracy było zbadanie wpływu protokołów doboru tras architektury TC/IP na funkcję i atrybuty przeżywalności. Pracę...
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Determination of the role of map kinase and PI3K/AKT signaling pathways in the regulation of multidrug resistance proteins in thyroid cancer
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Localization of key amino acid residues in the dominant conformational epitopes on thyroid peroxidase recognized by mouse monoclonal antibodies
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Relationships between concentrations of selected organohalogen contaminants and thyroid hormones and vitamins A, E and D in Faroese pilot whales
PublicationPilot whales (Globicephala melas) from the Faroe Islands, North-East Atlantic, have high body concentrations of organohalogenated compounds (OHCs), such as polychlorinated biphenyls (PCBs), organochlorinated pesticides (OCPs) and brominated flame retardants (BFRs). The aim of the present study was to examine if and to what extent blood plasma and liver concentrations of several groups of these OHCs are related to concentrations...
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Melatonin in the skin: synthesis, metabolism and functions
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Macroeconomic functions of the Russian stock market
PublicationThe purpose of this article is to present the structure of the stock market in the Russian Federation and the significance of this part of national financial system for the whole economy, particularly the degree of main macroeconomic functions fulfillment. First part of the text includes an overview of the main theoretical concepts linked with the stock market roles as well as a brief description of results of selected studies...
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SELECTION OF DIAGNOSTIC FUNCTIONS IN A WHEELED TRACTOR
PublicationIn a classical approach to damage diagnosis, the technical condition of an analyzed machine is identified based on the measured symptoms, such as performance, thermal state or vibration parameters. In wheeled tractor the fundamental importance has monitoring and diagnostics during exploitation concerning technical inspection and fault element localizations. The main functions of a diagnostic system are: monitoring tractor components...
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Offsetting, relations, and blending with perturbation functions
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MESOSCALE FUNCTIONS OF GPS SLANT DELAY
PublicationThe paper presents a computer module for GPS slant delay determination using data from COAMPS (Coupled Ocean/Atmosphere Mesoscale Prediction System) mesoscale non-hydrostatic model of the atmosphere which is run on IA64 Feniks computer cluster in the Department of Civil Engineering and Geodesy of the Military University of Technology. The slant delay is the result of integrating the ray (eikonal) equation for the spatial function...
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THERMOMECHANICAL PERFORMANCE OF FLEXIBLE POLYURETHANE FOAMS AS A FUNCTION OF THE ISOCYANATE INDEX
PublicationPolyurethane foams are very versatile materials applied in different branches of industry. Their popularity is attributed, among others, to the flexibility in engineering their mechanical performance by the adjustment of their formulations. One of the most crucial factors is the isocyanate index, determining the ratio between the free hydroxyl and isocyanate groups present in the polyurethane system. By the change of this ratio,...
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The agr function and polymorphism: Impact on Staphylococcus aureus susceptibility to photoinactivation
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Contribution of small heat shock proteins to muscle development and function
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