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Search results for: PARKINSON'S DISEASE
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Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
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Evaluating the Role of Circulating Dendritic Cells in Methimazole-Treated Pediatric Graves’ Disease Patients
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Regulatory B Cells Involvement in Autoimmune Phenomena Occurring in Pediatric Graves’ Disease Patients
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Environmental Factors and the Risk of Developing Type 1 Diabetes—Old Disease and New Data
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Evaluating the Role of Circulating Dendritic Cells in Methimazole-Treated Pediatric Graves’ Disease Patients
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Novel design of sodium alginate based absorbable stent for the use in urethral stricture disease
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Effects of Resveratrol Supplementation in Patients with Non-Alcoholic Fatty Liver Disease—A Meta-Analysis
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Craniofacial proportions in children with adenoid or adenotonsillar hypertrophy are related to disease duration and nasopharyngeal obstruction
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Tackling Alzheimer's disease: Hypothetical synergism between anti-inflammatory and anti-diabetic agents
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Stress and self-image in multiple sclerosis patients and selected positive aspects of struggling with the disease
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A response to “Cardiovascular disease and obstructive sleep apnea: an underappreciated role for increased platelet activity?”
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Hypertension and cardiovascular disease in women: Progress towards better understanding of gender‐specific differences?
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Analysis of exhaled breath for dengue disease detection by low-cost electronic nose system
PublicationThis paper presents a procedure and a set-up of an electronic nose system analyzing exhaled breath to detect the patients suffering from dengue – a mosquito-borne tropical disease. Low-power resistive gas sensors (MiCS-6814, TGS8100) were used to detect volatile organic compounds (VOCs) in the exhaled breath. The end-tidal phase of patients exhaled breath was collected with a BioVOCTM breath sampler. Two strategies were assessed...
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Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study
PublicationThe early atherosclerotic lesions develop by the accumulation of arterial foam cells derived mainly from cholesterol-loaded macrophages. Therefore, cholesterol and cholesteryl ester transfer protein (CETP) have been considered as causative in atherosclerosis. Moreover, recent studies indicate the role of trimethylamine N-oxide (TMAO) in development of cardiovascular disease (CVD). The current study aimed to investigate the association...
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Formulation and evaluation of hydrogel containing dry extract of Tormentillae rhizoma designed for periodontal disease
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Shub’s conjecture for smooth longitudinal maps of S^m
PublicationLet f be a smooth map of the m-dimensional sphere Sm to itself, preserving the longitudinal foliation. We estimate from below the number of fixed points of the iterates of f , reduce Shub’s conjecture for longitudinal maps to a lower dimensional classical version, and prove the conjecture in case m = 2 and in a weak form for m = 3.
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Correction to: Azo group(s) in selected macrocyclic compounds
PublicationIn the original publication of the article, a part of Scheme 12 was missed. The correct version of Scheme 12 was provided in this correction article. The original article has also been corrected.
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Badania strukturalne trialkoksysilanotiolanów wybranych metali bloku s
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Tris(4-morpholinecarbodithioato-κ2S,S')cobalt(III)
PublicationTytułowy niesolwatowany kompleks zawiera Co(III) skoordynowany przez trzy reszty chelatujące ditiokarbaminowe. Centralny rdzeń CoS6 tworzy zniekształcony oktaedr.
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Vitamin D receptor(s): In the nucleus but also at membranes?
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Reduced order models of refined Yee´s cells.
PublicationArtykuł opisuje nowe podejście zwiększające dokładność metody różnic skończonych za pomocą lokalnego zagęszczenia siatki. Obszar niewiele większy niż pojedyncza komórka Yee jest pokrywany gęstą siatką, a jej makromodel jest stworzony metodą redukcji rzędu modelu równań stanu w dziedzinie częstotliwości. Makromodele są użyte w metodach różnic skończonych w dziedzinie częstotliwości i czasu całej struktury. Inaczej niż w przypadku...
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Quantum morphogenesis: A variation on Thom`s catastrophe theory.
PublicationZaproponowano nowy opis morfogenezy na poziomie kwantowym w oparciu o rozwiązania samo przełączające nieliniowego równania von Neumanna.
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Synthesis of S-thioacyl dithiophosphates, efficient and chemoselectivethioacylating agents
PublicationŁatwo dostępne ditiofosforany acylu izomeryzują do monotiofosforanów O- iS-tioacylu. Reakcja jest odwracalna, więc ogrzewanie ditiofosforanów acylu prowadzi zazwyczaj do powstania mieszaniny izomerycznych bezwodników, która nie może być wykorzystana do wydajnego tioacylowania. Jednak działaniem kwasu ditiofosforowego na mieszaninę izomerycznych bezwodników można wydajnie otrzymać ditiofosforany tioacylu. Związki te to doskonałe...
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S-thioacyldithiophosphates in the synthesis of thiohydroxamic acids and O-thioacylhydroxylamines
PublicationDitiofosforany tioacylu to trwałe, łatwo osiągalne z kwasów karboksylowych środki tioacylujące. Z powodu ich niskiej reaktywności wobec nukleofili tlenowych i wysokiej wobec nukleofili azotowych znalazły zastosowanie w syntezie kwasów tiohydroksamowych bezpośrednio z hydroksyloamin z niechronioną grupą hydroksylową. W przypadku dużej zawady przestrzennej można otrzymać O-tioacylohydroksyloaminy.
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Application of Mazur-Orlicz`s theorem in AMISE calculation
PublicationW pracy podano nowe wyprowadzenie formuły asymptotycznej błędu aproksymacji dla operatorów całkowych w przestrzeniach niezmienniczych na przesunięcia. Obliczono asymptotykę błędu średniokwakratowego dla estymatora gęstości.
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S&YP + Mentors + Peace + Love = Science and Growing
PublicationIn this extraordinarily difficult time, we understand better that only peace, love, and cooperation are the keys to growing in technology for humanity. Let us learn from our mentors how they grow from their hard work and international cooperation. Thanks to Prof. Giuseppe Buja and Prof. Zbigniew Krzemiński, we have unique schools of adjustable speed drives that are helping people convert electrical to mechanical power and vice...
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Rezervuary s dvojnoj stenkoj - pocemu oni ispol'zuutsa?
PublicationOmówiono zalety i wady stalowych zbiorników dwupłaszczowych. Wskazano na zagrożenia które mogą wystąpić przy niefachowo prowadzonej próbie wodnej oraz nierównomiernym osiadaniu fundamentu.
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(S)-trans-cyclohexane-1,2-dicarboximide. Acta Cryst. Sect.C Crystal Struct.Commun.**2002 vol. 58 s. 0661-0662, 2 rys. 2 tab. bibliogr. 12 poz. Imid kwasu (S)-trans-cykloheksanodikarboksylowego.
PublicationAnaliza rentgenograficzna monokryształów imidu kwasu (S)-trans-cykloheksano-dikarboksylowego wykazała, że imidowy chromofor jest znacznie odkształconyod planarności. Fragment pięcioczłonowego pierścienia zawierający funkcjęimidową jest silnie pofałdowany i przyjmuje konformację typu półkrzesła.Pierścień sześcioczłonowy występuje w nieznacznie zniekształconej konforma-cji typu krzesło. W sieci krystalicznej cząsteczki...
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Sample preparation and recent trends in volatolomics for diagnosing gastrointestinal diseases
PublicationThe analysis of the human volatilome can be successfully used for rapid and non-invasive diagnostics of gastrointestinal diseases. However, the introduction of techniques based on detection of volatiles is limited, among other factors, by difficulties which arise during the sampling stage and instrumental analysis. The aim of this article was to review and discuss medical and analytical literature on the analysis of volatiles in...
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Metabolic profiling of pteridines for determination of potential biomarkers in cancer diseases
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Knowledge and Attitudes of Future Healthcare Professionals Toward Rare Diseases
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Dendrimer Structure Diversity and Tailorability as a Way to Fight Infectious Diseases
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Lipophagy and Lipolysis Status in Lipid Storage and Lipid Metabolism Diseases
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Factors and processes modulating phenotypes in neuronopathic lysosomal storage diseases
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Metals in the environment as risk factors for infectious diseases: gaps and opportunities
PublicationThis chapter aims to provide insights into current knowledge and gaps in our understanding of the influence that trace metals in the environment have on the pathogenesis of infectious diseases. By reducing immune function, trace metal deficiencies may substantially contribute to the global burden of diarhea, pneumonia, and malaria. Improved methods and biomarkers for assessing the risk of trace metals deficiencies and toxicities...
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OrphaGPT: An Adapted Large Language Model for Orphan Diseases Classification
PublicationOrphan diseases (OD) represent a category of rare conditions that affect only a relatively small number of individuals. These conditions are often neglected in research due to the challenges posed by their scarcity, making medical advancements difficult. Then, the ever-evolving medical research and diagnosis landscape calls for more attention and innovative approaches to address the complex challenges of rare diseases and OD. Pre-trained...
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Therapeutic Potential of Carnosine and Its Derivatives in the Treatment of Human Diseases
PublicationDespite significant progress in the pathogenesis, diagnosis, treatment, and prevention of cancer and neurodegenerative diseases, their occurrence and mortality are still high around theworld. The resistance of cancer cells to the drugs remains a significant problem in oncology today,while in the case of neuro-degenerative diseases, therapies reversing the process are still yet to be found. Furthermore, it is important to seek new...
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Tetra-n-butylammonium iodido(pyrrolidine-1-carbodithioato-κ2S,S')(tris-tert-butoxysilane-thiolato-κS)cadmate(II)
PublicationTytułowy (N,N tetrametylenoditiokarbaminiano)(tri-tert-butoksysilanotiolano)jodokadmian tetra-n-butyloamoniowy krystalizuje w układzie jednoskośnym, w grupie P21/c. W anionie [Cd{SSi(OtBu)3}(S2CNC4H9)I]() wyróżnić można centralny rdzeń o składzie CdS3I. Ułożenie atomów donorowych może być, w pierwszym przybliżeniu, opisane jako zniekształcony (ze względu na obecność S,S'-chelatującego liganda) tetraedr z największym kątem S1-Cd1-S2...
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Artificial intelligence support for disease detection in wireless capsule endoscopy images of human large bowel
PublicationIn the work the chosen algorithms of disease recognition in endoscopy images were described and compared for theirs efficiency. The algorithms were estimated with regard to utility for application in computer system's support for digestive system's diagnostics. Estimations were achieved in an advanced testing environment, which was built with use of the large collection of endoscopy movies received from Medical University in Gdańsk....
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Professional activity, gender and disease-related emotions: The impact on parents' experiences in caring for children with phenylketonuria
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Integrative multiomics study for validation of mechanisms in radiation-induced ischemic heart disease in Mayak workers
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Interaction of HLA-DRB1 Alleles with CTLA-4 in the Predisposition to Graves' Disease: The Impact of DRB1*07
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Professional activity, gender and disease-related emotions: The impact on parents' experiences in caring for children with phenylketonuria
PublicationIntroduction: Clinical management of rare diseases often fails to acknowledge the challenges faced by caregivers.Whilst management of phenylketonuria (PKU) may not be considered as dire as other conditions, most studiesprimarily concentrate on clinical issues, dietary adherence, or the quality of life of the PKU patients, leavingcaregivers in the background. The aim of the study was to evaluate the psychosocial...
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Ovocystatin Induced Changes in Expression of Alzheimer’s Disease Relevant Proteins in APP/PS1 Transgenic Mice
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Errorless Learning as a method of neuropsychological rehabilitation of individuals suffering from dementia in the course of Alzheimer’s disease
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Augmentation index, pulse pressure amplification and superoxide anion production in patients with coronary artery disease
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Influence of increased arterial stiffness on myocardial work efficiency in patients with stable coronary artery disease
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High prevalence of Escherichia coli belonging to the B2+D phylogenetic group in inflammatory bowel disease
PublicationBACKGROUND: It is not clear which species of bacteria may be involved in inflammatory bowel disease (IBD). One way of determining which bacteria might be likely candidates is to use culture-independent methods to identify microorganisms that are present in diseased tissues but not in controls. AIMS: (1) To assess the diversity of microbial communities of biopsy tissue using culture-independent methods; (2) to culture the bacteria...
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Sex contribution to average age at onset of Huntington's disease depends on the number of (CAG)n repeats
PublicationHuntington’s disease (HD) is a hereditary neurodegenerative disorder caused by the extension of the CAG repeats in exon 1 of the HTT gene and is transmitted in a dominant manner. The present study aimed to assess whether patients’ sex, in the context of mutated and normal allele length, contributes to age on onset (AO) of HD. The study population comprised a large cohort of 3723 HD patients from the European Huntington’s Disease...
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Detection of Alzheimer's disease using Otsu thresholding with tunicate swarm algorithm and deep belief network
PublicationIntroduction: Alzheimer’s Disease (AD) is a degenerative brain disorder characterized by cognitive and memory dysfunctions. The early detection of AD is necessary to reduce the mortality rate through slowing down its progression. The prevention and detection of AD is the emerging research topic for many researchers. The structural Magnetic Resonance Imaging (sMRI) is an extensively used imaging technique in detection of AD, because...