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Search results for: antidiabetic activity
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Amygdalin: Toxicity, Anticancer Activity and Analytical Procedures for Its Determination in Plant Seeds
PublicationAmygdalin (D-Mandelonitrile 6-O--D-glucosido--D-glucoside) is a natural cyanogenic glycoside occurring in the seeds of some edible plants, such as bitter almonds and peaches. It is a medically interesting but controversial compound as it has anticancer activity on one hand and can be toxic via enzymatic degradation and production of hydrogen cyanide on the other hand. Despite numerous contributions on cancer cell lines, the clinical...
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Characterization of PVDF/Graphene Nanocomposite Membranes for Water Desalination with Enhanced Antifungal Activity
PublicationSeawater desalination is a worldwide concern for the sustainable production of drinking water. In this regard, membrane distillation (MD) has shown the potential for effective brine treatment. However, the lack of appropriate MD membranes limits its industrial expansion since they experience fouling and wetting issues. Therefore, hydrophobic membranes are promising candidates to successfully deal with such phenomena that are typical...
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Hydrothermal Cobalt Doping of Titanium Dioxide Nanotubes towards Photoanode Activity Enhancement
PublicationDoping and modification of TiO2 nanotubes were carried out using the hydrothermal method. The introduction of small amounts of cobalt (0.1 at %) into the structure of anatase caused an increase in the absorption of light in the visible spectrum, changes in the position of the flat band potential, a decrease in the threshold potential of water oxidation in the dark, and a significant increase in the anode photocurrent. The material...
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PREPARATION AND CHARACTERIZATION OF CoFe2O4/TiO2-PANI HYBRID NANOCOMPOSITE WITH MAGNETIC AND PHOYOCATALYTIC ACTIVITY
PublicationHybrid nanocomposites consisting of inorganic component and organic conducting polymer are promising materials, which can be applied in heterogeneous photocatalysis. Titanium(IV) oxide is widely used photocatalysts due to its non-toxicity, low cost and chemical stability. The main disadvantage of TiO2 is low photocatalytic activity under visible light. Conducting polymers, also known as conjugated polymers are polymer materials...
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Activity of isavuconazole and other triazole derivatives against clinical isolates of Aspergillus fumigatus
PublicationAspergillus fumigatus is the most frequent pathogen of the genus Asperillus, which is highly susceptible to triazole derivatives, especially to isavuconazole and voriconazole. Many countries face a growing problem of infections due to A. fumigatus showing acquired resistance to one or several triazoles. In medical centres, monitoring the susceptibility of isolated Aspergillus spp. is recommended. The aim of this study was to collect...
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Transcriptional activity of epigenetic remodeling genes declines in keratinocytes after in vitro expansion
PublicationPURPOSE: In vitro expansion is an invaluable method to obtain keratinocytes in amounts necessary for effective transplantation therapies. In vitro cell culturing provokes questions concerning potential epigenetic alterations occurring in expanded cells in the context of usefulness for transplantation and safety. The purpose of this study was to investigate as to whether keratinocyte expansion is associated with changes in the activity...
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Honey antibacterial activity: A neglected aspect of honey quality assurance as functional food
PublicationBackground Honey is considered as a functional food with health-promoting properties. Its potent antibacterial and antibiofilm effects are the major attributes of so called ‘medical-grade honey’ which is topically used for the treatment of burns, wounds and skin disorders. Nevertheless, the current set of honey quality parameters adopted in the European Union do not include its biological properties. Furthermore, in light of the...
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Influence of Annealing Atmospheres on Photoelectrochemical Activity of TiO2 Nanotubes Modified with AuCu Nanoparticles
PublicationIn this article, we studied the annealing process of AuCu layers deposited on TiO2 nanotubes (NTs) conducted in various atmospheres such as air, vacuum, argon, and hydrogen in order to obtain materials active in both visible and UV–vis ranges. The material fabrication route covers the electrochemical anodization of a Ti plate, followed by thin AuCu film magnetron sputtering and further thermal treatment. Scanning electron microscopy...
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The Effect of Conjugation with Octaarginine, a Cell-Penetrating Peptide on Antifungal Activity of Imidazoacridinone Derivative
PublicationAcridine cell-penetrating peptide conjugates are an extremely important family of compounds in antitumor chemotherapy. These conjugates are not so widely analysed in antimicrobial therapy, although bioactive peptides could be used as nanocarriers to smuggle antimicrobial compounds. An octaarginine conjugate of an imidazoacridinone derivative (Compound 1-R8) synthetized by us exhibited high antifungal activity against reference...
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Solid phase synthesis and biological activity of linear tuftsin and retro-tuftsin derivatives
PublicationPrzedstawiono syntezę na fazie stałej nowych pochodnych tuftsyny i retro-tuftsyny i ich mikrobiologiczne właściwości. Otrzymane pochodne zawierały wiązanie izopeptydowe między epsilon-aminową grupą lizyny a takimi aminokwasami jak: Ala, beta-Ala, Val, Ile, Gly.
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Structural determinants of imidazoacridinones facilitating antitumor activity are crucial for substrate recognition by ABCG2
PublicationW pracy zidentyfikowaliśmy elementy struktury chemicznej dla 23 pochodnych imidazoakrydonu odpowiedzialne za ich rozpoznawanie przez transporter typu ABC, białko ABCG2. za transport tych związków przez pompę ABCG2 odpowiedzialne jest grupa hydroksylowa w pozycjach R1, R2 i R3 chromoforu. Stwierdziliśmy także, że zwiększanie ilości grup metylenowych łańcucha bocznego imidazoakrydonów powodowało zmniejszenie aktywnego transportu...
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Hypsometric changes in urban areas resulting from multiple years of mining activity
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Institutional Settings and their Impact on the IPO Activity: An Exploratory Study Based on Qualitative Modelling
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Nutritional Value and Biological Activity of Gluten-Free Bread Enriched with Cricket Powder
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Tribenzoporphyrazines with dendrimeric peripheral substituents and their promising photocytotoxic activity against Staphylococcus aureus
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Membrane Filtration-Assisted Enzymatic Hydrolysis Affects the Biological Activity of Potato Juice
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Photochemical properties and promising activity against staphylococci of sulfanyl porphyrazines with dendrimeric moieties
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Thymus serpyllum Essential Oil and Its Biological Activity as a Modern Food Preserver
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Synthesis of 5-arylidene-2-amino-4-azolones and evaluation of their anticancer activity
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Synthesis, biological activity and molecular modelling studies of tricyclic alkylimidazo-, pyrimido- and diazepinopurinediones
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The lipophilicity estimation of 5-arylidene derivatives of (2-thio)hydantoin with antimycobacterial activity
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<p>Analysis of toxicity and anticancer activity of micelles of sodium alginate-curcumin</p>
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Impact of paint matrix composition and thickness of paint layer on the activity of photocatalytic paints
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Cinnamon powder: an in vitro and in vivo evaluation of antifungal and plant growth promoting activity
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Photocatalytic activity of anatase powders for oxidation of methylene blue in water and diluted NO gas
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Synthesis of Usnic Acid Derivatives and Evaluation of Their Antiproliferative Activity against Cancer Cells
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Activity and discrimination against women in the labour market in the countries of Baltic Sea Region
PublicationAn increasing participation of women in the labour market seem to be a key to overcome the problems of the EU labour market and to achieve the objectives of Strategy Europe 2020. Therefore, the objective of this paper is to identify differences in the situation of women in the labour market in selected countries such as those in the Baltic Sea region and to attempt to verify the hypothesis of the existence of discrimination against...
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Phosphate tricyclic coumarin analogs as steroid sulfatase inhibitors: synthesis and biological activity.
PublicationIn the present work, we report convenient methods for the synthesis and biological evaluation of phosphate tricyclic coumarin derivatives as potential steroid sulfatase inhibitors. The described synthesis includes the straightforward preparation of 7-hydroxy-2,3-dihydro-1H-cyclopenta[c]chromen-4-one, 3-hydroxy-7,8,9,10-tetrahydro-6H-benzo[c]chromen-6-one and 3-hydroxy-8,9,10,11-tetrahydro-7H-cyclohepta[c]chromen-6-one modified...
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INFLUENCE OF TEMPERATURE ON THE ACTIVITY OF ANAMMOX GRANULAR BIOMASS - SHORT AND LONG-TERM ASPECT
PublicationThe aim of this study was to determine a short-term and long-term effect of temperature on the anammox process rate and determination of temperature coefficients in the Arrhenius and Ratkowski equations. The short-term effects of temperature on the anammox biomass were investigated in batch tests at ten different temperatures in the range of 10-55 ̊C. The maximum rate 1.3 gN (gVSS·d)-1 observed at 40 ̊C. The minimum rate, close...
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Effect of self-assembly on antimicrobial activity of double-chain short cationic lipopeptides
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Effect of extraction method on the antioxidative activity of ground elder (Aegopodium podagraria L.)
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Actions of a nitric oxide donor on prostaglandin production and angiogenic activity in the equine endometrium
PublicationNitric oxide (NO) plays an important role in prostaglandin secretion and angiogenesis in the reproductive system. In the present study, the roles of the NO donor spermine NONOate and tumour necrosis factor-alpha (TNF; as a positive control) in prostaglandin production and angiogenic activity of equine endometria during the oestrous cycle were evaluated. In addition, the correlation between NO production...
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Lysozyme increases bactericidal activity of ceragenin CSA-13 against Bacillus subtilis
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Enhanced Suppressive Activity of Regulatory T Cells in the Microenvironment of Malignant Pleural Effusions
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Use of magnetic nanoparticles as a drug delivery system to improve chlorhexidine antimicrobial activity
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Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach
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Comparison of antifungal activity of extracts from different Juglans regia cultivars and juglone
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Effect of biochar activation by different methods on toxicity of soil contaminated by industrial activity
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Spectroscopic and Spectroelectrochemical Studies on Redox Properties of Zinc Sulfide and Their Consequences on Photocatalytic Activity
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Physical Activity vs. Redox Balance in the Brain: Brain Health, Aging and Diseases
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Vimentin immunoexpression and its prognostic activity in colon cancer among Caucasian patients
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Gender-Selective Interaction Between Aging, Blood Pressure, and Sympathetic Nerve Activity
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Detection of low- and high-frequency rhythms in the variability of skin sympathetic nerve activity
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Central Vagotonic Effects of Atropine Modulate Spectral Oscillations of Sympathetic Nerve Activity
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Relationship Between Muscle Sympathetic Nerve Activity and Diurnal Blood Pressure Profile
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Baroreflex Control of Sympathetic Nerve Activity and Heart Rate in Obstructive Sleep Apnea
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Interactive Effect of Heart Rate and Muscle Sympathetic Nerve Activity on Blood Pressure
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Residual Effects of Different Cropping Systems on Physicochemical Properties and the Activity of Phosphatases of Soil
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The time spent sitting does not always mean a low level of physical activity
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Interleukin 12 and indomethacin exert a synergistic, angiogenesis-dependent antitumor activity in mice
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