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Search results for: lysosomal world
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Abnormal Sphingolipid World in Inflammation Specific for Lysosomal Storage Diseases and Skin Disorders
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Genistein: a lysosomal stimulator for treatment of various lysosomal diseases
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Combined Therapies for Lysosomal Storage Diseases
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Imidazoacridinone-dependent lysosomal photodestruction: a pharmacological Trojan horse approach to eradicate multidrug-resistant cancers
PublicationMultidrug resistance (MDR) remains a primary hindrance to curative cancer therapy. Thus, introduction of novel strategies to overcome MDR is of paramount therapeutic significance. Sequestration of chemotherapeutics in lysosomes is an established mechanism of drug resistance. Here, we show that MDR cells display a marked increase in lysosome number. We further demonstrate that imidazoacridinones (IAs), which are cytotoxic fluorochromes,...
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Lysosomal ceramide mediates gemcitabine-induced death of glioma cells
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Factors and processes modulating phenotypes in neuronopathic lysosomal storage diseases
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Scientists in the world of business
PublicationArtykuł promujący działania badawczo-rozwojowe Zakładu Zarządzania Technologiami Informatycznymi Wydziału Zarządzania i Ekonomii Politechniki Gdańskiej.
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The molecular mechanism of genistein action in lysosomal storage diseases: A transcriptomic approach
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Political Parties in the Digital World
PublicationThe aim of this report is to outline how digital technologies and digital media are redefining the way political parties fulfill their role as collective platforms for political participation of citizens, e.g. in relation to the parties’ decision-making processes, communication strategies, funding mechanisms, membership, information sharing, etc. and to highlight the existing international standards and good practices in this area....
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The Phytoestrogen Genistein Modulates Lysosomal Metabolism and Transcription Factor EB (TFEB) Activation
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Photodynamic therapy of cancer with liposomal photosensitizers
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Current status of liposomal porphyrinoid photosensitizers
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Non-standard errors in the cryptocurrency world
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Technology of real-world analyzers (TAUR)
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4D Models in World Wide Web
PublicationThe paper presents some results of research curried out within the framework of the European project named "Cultural Heritage Through Time" (CHT2). One of the main project aims were to develop a methodology for sharing multi-temporal information via the Internet (webGIS) for remote analysis of structures and landscapes over time. Reported in this paper results are focused on testing two technologies (Hexagon and Esri) for online...
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Future Skills and Education in a Computerized World
PublicationAs computerization of Western economies has advanced, the supply of the demand for routine cognitive tasks and routine manual tasks has fallen. Computerization has increased labour input of nonroutine cognitive tasks which has favourized high educated workers. Similarly, there is clear evidence of an increase in demand for high skilled workforce which originates from poor machine performance of nonroutine...
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China and the Chinese in the modern world. An interdisciplinary study
PublicationThis monograph is a collection of chapters devoted to modern China on various approaches. There is no future without a past and a modern China is a country that skillfully combines the new with the old and the authors have attempted to present this phenomenon in this book. It brings to light issues such as a honorificativity in Chinese administrative and legal documents, a comparison of Chinese and...
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Responsible Court in the Global World - Managerism or Managerialism
PublicationOne can look at the improvement of the effectiveness and efficiency of the justice system from three perspectives: macro, mezo, and micro. After all, the general goal is to enhance the effectiveness and efficiency of the justice system as a whole (the macro perspective), the courts (the mezo scale), and court proceedings (the micro scale). The need to improve the effectiveness and efficiency of the justice system was noticed in...
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Occupational Health and Safety in the World of Digitalizing Work
PublicationWhen employees have a sense of work well-being and safety, so shall the employer organization thrive. In the digitized work content, also called the Forth Industrial Revolution or Industry 4.0, employer organizations prioritize faster or efficient production with ever more precise decision-making, entirely and workflow for task accomplishment of which employees and employer organizations are learning “on-the-go” how to manage the...
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Cyclosporine CsA—The Physicochemical Characterization of Liposomal and Colloidal Systems
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The surprising world of cyanobacteria: cylindrospermopsin has a soil face
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Precarious manhood and men’s physical health around the world.
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Resilience as a Sustainable Design Process in the World Climate Change
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Designing world closures for knowledge-based system engineering
PublicationWraz z rozwojem komponentów opartych na wiedzy przed inżynierami oprogramowania postawione zostały nowe zadania. Jednym z nich jest zintegrowanie tych komponentów z innymi standarodowymi komponentami. Zrealizowanie tego zadania wymagało zdefiniowania języka komunikacji pomiędzy różnymi komponentami w celu wymiany informacji. W artykule omówiono problem wymiany informacji pomiędzy komponentami opartymi na wiedzy i komponentami opartymi...
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Globalisation and world economic poverty: The significance of hidden dimensions
PublicationThe aim of our research is to examine how individual dimensions of globalization affect economic poverty in the World. for this, regression models are estimated with FGT0 or FGT1 poverty measures as dependent variables and KOF indices of globalization as despendent variables. The poverty indices are estimated for 119 countries' income didtributions assuming log-normality and using Gini estimates from the WID2 database and GDP/capita...
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On the Importance of Resilience Engineering for Networked Systems in a Changing World
PublicationResilience is featured increasingly often in the media, usually applied to society when faced, for example, with disasters such as flooding and the enormous challenges that the Covid-19 pandemic posed. There are now many resilience-related discussion groups worldwide, and some standards initiatives devoted in particular to city resilience. However, there is relatively little explicit interest in resilience engineering for communication...
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The Role of Dimethyl Sulfoxide (DMSO) in Gene Expression Modulation and Glycosaminoglycan Metabolism in Lysosomal Storage Disorders on an Example of Mucopolysaccharidosis
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Changes in shares outstanding and country stock returns around the world
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Geo-engineering computer simulation seems attractive but is it the real world?
PublicationCorrect formulation of the differential equation system for equilibriom conditions of subsoil, especially in terms of controlled numerical calculation, is discussed. The problem of solution stability is also considered. The solution of problems, which are ill-posed, have no practical value in the majority of cases and is this way the engineering prognosis can lead to real disaster. The object of this paper is quite relevant if...
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Colour Terms in Five Linguistic Images of the World: The Semantic Perspective
PublicationSocial and cultural factors shape the linguistic perception of colour. At the same time, colour terms co-create the linguistic image of the world, which allows us to interpret reality and profile our statements and beliefs. This paper presents six basic colour terms: white, black, red, green, yellow, and blue (both as adjectives and as nouns) in the five different linguistic images of the world of the following languages: English,...
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Gdynia's Modernism between the World Wars. The Stylistic Face of the Epoch
PublicationThe article presents the styles in the architecture of Gdynia in 1920s and 1930s
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Glaciers as an Important Element of the World Glacier Monitoring Implemented in Svalbard
PublicationGlaciers are not only contributors to the sea level rise but also important players in the circulation of pollutants. Over a billion people apply glacial waters for domestic purposes; hence, both the quality and quantity of this water should be monitored. In this chapter, we concentrate on the archipelago Svalbard in the Arctic, a typical target area for xenobiotics from long range atmospheric transport (LRAT), holding an important share...
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Fourth industrial revolution and new challenges in post-pandemic world
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Liposomal Nanoformulation as a Carrier for Curcumin and pEGCG—Study on Stability and Anticancer Potential
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Sprawozdanie z międzynarodowej konferencji naukowej A Lost World? Jewish International Lawyers and New World Orders (1917–1951), Jerozolima, 24–25 maja 2021 r.
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World Wide Web CBIR Searching Using Query by Approximate Shapes
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A Surrounding World Knowledge Acquiring by Using a Low-cost Ultrasound Sensors
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Possible uses of crisis situation aiding system in virtual world simulation
PublicationMany of the real world crisis situations like spreading fire, hostile units attack, flood, and etc. are commonly used in computer games where a simulation of extensive virtual world is crucial. This paper presents some ideas for possible uses of existing crisis situation aiding system in such environments. Moreover it shows how this kind of system can be taught during subsequent games with a large number of players.
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Possible uses of crisis situation aiding system in virtual world simulation
PublicationMany of the real world crisis situations like spreading fire, hostile units attack, flood, and etc. are commonly used in computer games where a simulation of extensive virtual world is crucial. This paper presents some ideas for possible uses of existing crisis situation aiding system in such environments. Moreover, it shows how this kind of system can be taught during subsequent games with a large number of players. As an example...
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Social development and ICT adoption. Recent evidence from developing world
PublicationThis paper is designed to provide empirical evidence on the relationship between the process of ICT diffusion and social development across selected low-income and lowermiddle- income countries during the period of 2000 and 2014. It main target it so identify whether in low-income and lower-middle-income economies, ICT development and social development (social empowerment) are correlated.
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The assessment of renewable energy in Poland on the background of the world renewable energy sector
PublicationThe issues of the article are associated with the development of the renewable energy source (RES) sector in the world and in Poland. The subject is undoubtedly connected with the problem of the energy transformation taking place in most countries nowadays. Energy transformation processes are mainly associated with an increase in the share of energy production from RES and increased awareness of energy use by end consumers. This...
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Analysing By-Products Interaction as an Industry Resource of Circular Economy in Ukraine and the World
PublicationThe paper analyses existing and current scientific developments and literature sources, which show the advantages and disadvantages of many different influences of waste in Ukraine and other countries of Europe and the world. As a research result, stable connections have been established between the factors and criteria in assessing the by-product interaction as an industry resource. In our research, we used programs R.Studio and...
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Very High Frequency Technique Laboratory - First Step to the World of Microwaves
PublicationArtykuł opisuje nowe podejście do zajęć dydaktycznych związanych z przedmiotem Technika Bardzo Wysokich Częstotliwości.
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Endocrine disrupting compounds in the baby's world - A harmful environment to the health of babies
PublicationGlobally, there has been a significant increase in awareness of the adverse effects of chemicals with known or suspected endocrine-acting properties on human health. Human exposure to endocrine disrupting compounds (EDCs) mainly occurs by ingestion and to some extent by inhalation and dermal uptake. Although it is difficult to assess the full impact of human exposure to EDCs, it is well known that timing of exposure is of importance...
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Activity ofα1-Antitrypsin and Some Lysosomal Enzymes in the Blood Serum of Patients with Chronic Obstructive Pulmonary Disease after Smoking Cessation
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Modulation of expression of genes involved in glycosaminoglycan metabolism and lysosome biogenesis by flavonoids
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Świat ugrofiński w słownikach polskich [The Finno-Ugric world in Polish dictionaries]
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German Jews in Jelenia Góra immediately After the End of the Second World War
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Photovoltaic solar cells and modules as the source of electricity in the world and its future in Poland
PublicationJedną z metod ograniczenia emisji CO2 na świecie i w Polsce jest zastępowanie paliw kopalnych odnawialnymi źródłami energii. Systemy fotowoltaiczne, generujące energie elektryczną, są uważane za technologię wpisująca się w politykę zrównoważonego rozwoju dzięki znacznemu postępowi technologicznemu w zakresie ich wytwarzania i znacznej redukcji kosztów tych systemów.W artykule naświetlono postęp, jaki dokonał się w tej dziedzinie...
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Can architecture be 11-dimensional? The nature of space in the architecture of the digital world era
PublicationThis research aims to explore the development of architectural theories about ‘architectural dimensions’ and look at architecture as a multidimensional space. It is important to understand that with today's development of virtual reality technology and through the combination of theories of physics and architecture, a new possibility of creating space has emerged. The arguments are made through inductive reasoning and grounded...