Search results for: therapeutic landscapes
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Sem VI_ENG_Theory of landscape design
e-Learning CoursesTheory of landscape design SDGs in landscape design Technical detailing of landscaping solutions
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Karolina Krośnicka dr hab. inż. arch.
PeopleKarolina A. Krośnicka, Ph.D., D.Sc., Eng. Arch., is associated professor at Department of Urban Design and Regional Planning, Faculty of Architecture, Gdańsk University of Technology (Poland). For many years (1998 – 2016) she was employed at the Department of Transport and Logistics at the Faculty of Navigation at Gdynia Maritime University (Gdynia, Poland), where she was mostly involved in issues connected with seaports and port...
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The green waterfront of a city. Where are the limits of good planning? Gdansk case
PublicationThe aim of the article is to present the role of green public areas of waterfronts in shaping the image of cities, and the threats to such landscape which may be caused by wrong planning decisions. The case study of Gdansk sea-shore area in Poland is presented as an example to illustrate the values and potential of the waterfront landscape which can be easily destroyed by inadequate spatial development. Some theoretical studies...
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Hanna Obracht-Prondzyńska dr inż. arch.
PeopleHanna Obracht-Prondzyńska, PhD MArch, Eng. Assistant Professor at the University of Gdańsk, Department of Spatial Management, academic teacher of urban design and spatial data analyses. Architect and urban planner experienced in data driven urban design and planning. She defended her PhD with distinction in engineering and technical sciences in the discipline of architecture and urban planning in 2020 at the Faculty of Architecture...
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Results of modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models using Saccharomyces cerevisiae yeast as model organism
Open Research DataThe research was concerned with verifying the impact of binary mixtures of nine pharmaceuticals against a selected organism, i.e., the yeast Saccharomyces cerevisiae. S cerevisiae is used as a model organism in the monitoring of endocrine disruptors in environmental and reference samples in Xenometrix® systems - XenoScreen®. Tested pharmaceuticals,...
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Rospuda - czy wszędzie budować mosty?
PublicationStreszczenie - SummaryThe article presents the problem of planning transport system in the areas of high natural and landscape values. Bridges and roads crossing valuable areas undergo Environmental Impact Assessment (EIA) Procedure. This procedure in Poland is often treated only as formal requirement, not as an instrument helping to solve conflicts and to minimise negative environmental and landscape effects. The potential of...
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Wieloletnie obserwacje soplówki jeżowatej Hericium erinaceum (Bull.: Fr.) Pers. (macromycetes) na stanowisku w Lasach Oliwskich (Trójmiejski Park Krajobrazowy) = Long-term observation of bearded tooth fungus Hericium erinaceum (Bull.: Fr.) Pers. (macromycetes) in Oliwskie Forests (Trójmiejski Landscape Park)
PublicationW pracy omówiono soplówkę jeżowatą oraz podano miejsca jej występowania w kraju i za granicą. Szczegółowo opisano stanowisko soplówki jeżowatej w Lasach Oliwskish w Trómiejskim Parku Krajobrazowym.
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Results of pharmaceuticals mixtures toxicity on inhibition of bioluminescence of Vibrio fischeri (Microtox)
Open Research DataThe research was concerned with verifying the impact of mixtures of nine pharmaceuticals against a selected organism, i.e., the bacterium Aliivibrio fischeri. A. fisheri is used as a model organism in the monitoring of acute toxicity in environmental and reference samples in Microtox® systems. Tested pharmaceuticals, namely: diclofenac (sodium salt),...
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The role of glucuronidation in drug resistance
PublicationThe final therapeutic effect of a drug candidate, which is directed to a specific molecular target strongly depends on its absorption, distribution, metabolism and excretion (ADME). The disruption of at least one element of ADME may result in serious drug resistance. In this work we described the role of one element of this resistance: phase II metabolism with UDP-glucuronosyltransferases (UGTs). UGT function is the transformation...
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SENSORY GARDENS INCLUSIVELY DESIGNED FOR VISUALLY IMPAIRED USERS.
PublicationThis paper discusses the design of sensory gardens, created especially to provide for the needs of sight impaired children and youth. These gardens should be inclusively available to general public. A sensory garden may have both therapeutic and educational effects. The research findings concerning therapeutic effects of contact with nature on children and youth are reviewed. The design problems related to providing a space for...
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Modifications of total synthesis of mycophenolic acid
PublicationThe total synthesis of mycophenolic acid (MPA), a potent immunosuppressant, was modified. The obtained mycophenolic acid was suitable for further preparation of new prospective immunosuppressants with improved therapeutic properties.
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Space and Landscape in a Global Context
e-Learning CoursesModule SPACE AND LANDSCAPE IN A GLOBAL CONTEXT (2022/2023, autumn semester) Objective The objective of the module is to debate different approaches to managing spatial development and contemporary issues in a global context. The course is founded on the students' knowledge about urban planning and instruments used to make them better places both for people and the environment. Course proceedings Lectures and classes run online...
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23/24_S6_Eng_Theory of landscape design
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The Concept of Construction of Hybrid Constructed Wetland for Wastewater Treatment in Roztocze National Park
PublicationRoztocze National Park (RNP) is one of 23 national parks in Poland. It was created in 1974 both to protect the natural and cultural heritage as well as to share the park area for science, education and tourism. In caring for the environment, the park removed asbestos coverage, performs thermo-modernization using renewable energy sources by the installation of solar panels and photovoltaic cells on the roofs of buildings, and pellet...
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Deterministic versus stochastic modelling of unsaturated flow in a sandy field soil based on dual tracer breakthrough data
PublicationThe 216 km2 Neuenhagen Millcreeck catchment can be characterized as a drought sensitive landscape in NE Germany. It is therefore a fundamental human interest to understand how water that fell as precipitation moves through the unsaturated soils and recharges groundwater. Additionally, a better knowledge of nutrient transport from soil to groundwater is important also, especially in landscapes with light sandy soils. For a better...
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Application of a three‑dimensional (3D) breast cancer model to study macrophage polarization
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Lucyna Nyka prof. dr hab. inż. arch.
PeopleLucyna Nyka (Ph.D., D.Sc., Prof.) is a Professor at the Faculty of Architecture, Gdańsk University of Technology, in 2008-2016 a Vice-Dean for Research, and since 2016 – Dean of the Faculty of Architecture. Her research interests focus on issues concerning water-related architecture and urban landscapes. She is the author and co-author of many projects focused on urban renewal. She was an author of the EU-founded (Audiovisual...
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Nanomaterials for photothermal and photodynamic cancer therapy
PublicationIn recent years, the role of optically sensitive nanomaterials has become powerful moieties in therapeutic techniques and has become particularly emphasized. Currently, by the extraordinary development of nanomaterials in different fields of medicine, they have found new applications. Phototherapy modalities, such as photothermal therapy (PTT) by toxic heat generation and photodynamic therapy (PDT) by reactive oxygen species, are...
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Piotr Marek Smolnicki dr inż. arch.
PeopleAuthor, speaker, architect-urban planner, Ph.D. in the topic of automated and shared metropolitan mobility, a municipal advisor on public participation processes in urban planning, editor of so-called landscape protection acts.
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The concept of the terrestrial–subaqueous topographical and lithological continuum: a case study of the Lake Gopło region (north-central Poland)
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Rural Design Lectures
e-Learning CoursesThe lectures are aiming to provide the students with the general understanding of the vernacular architecture, landscape, future, resilience and history.
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Theory of Rural Design 2023
e-Learning CoursesThe lectures are aiming to provide the students with the general understanding of the vernacular architecture, landscape, future, resilience and history.
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An Island of Connectedness: Intra-Insular and Inter-Regional Communications of Rab Island (North-East Adriatic, Kvarner Gulf), Croatia
PublicationDrawing from archaeological data on Prehistoric and Roman settlement patterns, and respective sepulchral features, just as on later historic and cartographic sources, in this contribution it will be shown how movement along with mobility influenced on and were an integral part of settlement dynamics on the island of Rab (NE Adriatic, Croatia). The employed approach sees the practice of movement as dependent on specific social...
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Gabriela Rembarz dr inż. arch.
PeopleGabriela Rembarz inżynier-architekt, urbanista, naukowiec, dydaktyk i aktywna projektantka, jest doktorem nauk technicznych w dyscyplinie architektura i urbanistyka, Ukończyła studia magisterskie na Wydziale Architektury i Urbanistyki Politechniki Gdańskiej, uzupełniając je specjalizacją w Ochronie Środowiska w ramach międzyuczelnianego CENVIG Center of Environmental Studies (Politechnika Gdańska) akredytowanego przez Roskilde...
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EPILEPTIC BEHAVIOR WITH A DISTINGUISHED PREICTAL PERIOD IN A LARGE-SCALE NEURAL NETWORK MODEL
PublicationWe present a neural network model capable of reproducing focal epileptic behavior. An important property of our model is the distinguished preictal state. This novel feature may shed light on the pathologi-cal mechanisms of seizure generation and, in perspective, help develop new therapeutic strategies to manage refractory partial epilepsy.
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Justyna Borucka dr inż. arch.
PeopleJustyna Borucka is an Assistant Professor at the Faculty of Architecture, Gdańsk University of Technology, Coordinator of Erasmus Programme and International Cooperation and since 2016 a Vice-Dean for Development. She is also board member of Polish Architects Association (SARP o.Wybrzeże). Her research focused on theory of architecture and strategies for urban renewal with the special impact of interdisciplinary relationships...
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Polish Lymphoma Research Group Experience With Bexarotene in the Treatment of Cutaneous T-Cell Lymphoma
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Safety and efficacy of P2X3 receptor antagonist for the treatment of refractory or unexplained chronic cough: A systematic review and meta-analysis of 11 randomized controlled trials
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DNA methylation analysis with methylation‐sensitive high‐resolution melting (MS‐HRM) reveals gene panel for glioma characteristics
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Squares in Gdansk as a City Value = Skwery, jako wartościowe przestrzenie publiczne Gdańska
PublicationThe article emphasizes potential of public urban squares. The attention is focused on squares of the city of Gdansk which constitute the potential for enhancing the image of the city. Presentation of three examples of small scale intervention in the Montreal's public spaces is depicting such a potential and is underlining different roles the public space can perform in the city structure. Revitalization of urban squares is influencing...
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SZTUKA WIZUALNA W OBIEKTACH MEDYCZNYCH = VISUAL ARTS IN MEDICAL FACILITIES
PublicationWspółczesna architektura obiektów służby zdrowia podlega dynamicznym przeobrażeniom formalnym wynikającym zarówno z rozwoju technologii medycznych, zmian zachodzących w podejściu wobec pacjenta. Narastający w naukach medycznych kierunek holistyczny ustawia pacjenta jako użytkownika w trzech wymiarach: biologicznym, społecznym i psychologicznym. Stąd pojawiające się w procesie projektowym dotyczącym szpitali czy przychodni nowe...
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Green Therapy w projektowaniu ośrodków medycznych Green Therapy in complex design of health centres
PublicationKoncepcja przestrzenna ogrodu terapeutycznego podporządkowana jest generalnej idei otwierania się projektantów na poszukiwanie nowych możliwości poprawy samopoczucia odbiorcy - poprzez zapewnienie użytkownikom poczucia bezpieczeństwa, komfortu i odprężenia, harmonii. Dotyczy to nie tylko grupy osób chorych, które dręczone są przez niepokoje i napięcia wywołane przez niepełnosprawność czy chorobę, ale także pacjentów w różnym wieku...
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Space and Landscape in a Global Context - 2023/24
e-Learning CoursesModule SPACE AND LANDSCAPE IN A GLOBAL CONTEXT (2022/2023, autumn semester) Objective The objective of the module is to debate different approaches to managing spatial development and contemporary issues in a global context. The course is founded on the students' knowledge about urban planning and instruments used to make them better places both for people and the environment. Course proceedings Lectures and classes run online...
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Pharmaceutical applications of surfactants
PublicationIn this study we focused on biological activity of various surfactants. According to our research, they con act both as carriers as well as therapeutic agents. Depending on their concentration, they can create different structures in a solution, which influence their properties. Liposomes have a significant role in drug delivery system. Surfactants in from of bilayer are analogous to natural biological cell membrane.
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Creating a radiological database for automatic liver segmentation using artificial intelligence.
PublicationImaging in medicine is an irreplaceable stage in the diagnosis and treatment of cancer. The subsequent therapeutic effect depends on the quality of the imaging tests performed. In recent years we have been observing the evolution of 2D to 3D imaging for many medical fields, including oncological surgery. The aim of the study is to present a method of selection of radiological imaging tests for learning neural networks.
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Container
PublicationThe main aim of the project is to improve interpersonal communication and promote better functionality in the City of Hamburg. An important element is to satisfy the needs of people living and working in diff erent districts. In our project, we sought to give people an outlet and enabled the possibility of creating landscapes. The unusual advantage of the city is that it allows the use of waterways, which in turn become a link...
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Third sector characteristics and importance
PublicationThis article aims to present a brief overview of existing definitions and specific characteristics of the third sector. It also highlights the basic functions of NGOs as an important institutional and organizational actor in the global political and economic landscape.
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Antimicrobial peptides (AMPs) as drug candidates: a patent review (2003–2015)
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Inhibitors of cathepsin G: a patent review (2005 to present)
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Pregnane X receptor dependent up-regulation of CYP2C9 and CYP3A4 in tumor cells by antitumor acridine agents, C-1748 and C-1305, selectively diminished under hypoxia
PublicationInduction of proteins involved in drug metabolism and in drug delivery has a significant impact on drug-drug interactions and on the final therapeutic effects. Two antitumor acridine derivatives selected for present studies, C-1748 (9-(2’-hydroxyethylamino)-4-methyl-1-nitroacridine) and C-1305 (5-dimethylaminopropylamino-8-hydroxy-triazoloacridinone), expressed high and low susceptibility to metabolic transformations with liver...
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Analysis of multi-class pharmaceuticals in fish tissues by ultra-high-performance liquid chromatography tandem mass spectrometry
PublicationA new sensitive method based on pressurized liquid extraction (PLE) and purification by gel permeation chromatography (GPC) prior to ultra-high-performance liquid chromatography coupled to tandem mass spectrometry (UHPLC–MS/MS) was developed for the determination in fish homogenate, liver and muscle of twenty pharmaceuticals compounds and metabolites from seven commonly used therapeutic families. An extensive matrix effect evaluation...
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Phage Therapy—Challenges, Opportunities and Future Prospects
PublicationThe increasing drug resistance of bacteria to commonly used antibiotics creates the need to search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly. Phages that selectively infect and kill bacteria are often the only life-saving therapeutic option. Full legalization of this treatment method could help solve the problem of multidrug-resistant infectious diseases on a global scale. The aim of...
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Results of modeling of pharmaceuticals mixtures toxicity with deviation ratio and best-fit functions models using Aliivibrio fischeri bacterium as model organism
Open Research DataThe research was concerned with verifying the impact of mixtures of nine pharmaceuticals against a selected organism, i.e., the bacterium Aliivibrio fischeri. A. fisheri is used as a model organism in the monitoring of acute toxicity in environmental and reference samples in Microtox® systems. Tested pharmaceuticals, namely: diclofenac (sodium salt),...
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Persistences: analysis of the image of Gdańsk and its cultural identity through survey processes and digital architectural representation
PublicationThe aim of the research was to analyse the historical legacy/heritage of the city of Gdańsk in order to characterise the narrative tools which can be used to promote the cultural identity of the urban landscape. The main focus was on the city's defence system - a cultural route that is spatially limited to a relatively small area, but temporally spanning almost a millennium. The fortifications demarcate a spatial boundary, limiting...
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Alternative treatment approaches of urinary tract infections caused by uropathogenic Escherichia coli strains
PublicationUrinary tract infections (UTIs) are the most widespread and annoying infections affecting millions of people every year annually. The biggest problem of urinary diseases are recurrences, the increasing resistance of uropathogens to commonly used antibiotics, as well as the high health care costs of afflicted persons. Uropathogenic Escherichia coli strains (UPECs) are the most dominant etiologic agent of community-acquired infections...
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Praca z drewnem - Przestrzeń eksperymentu w tworzeniu architektury; Crafting Wood - Space of experiment in making architecture
PublicationW artykule przedstawiono eksperymenty z materiałem w tworzeniu architektury prowadzące do praktycznych rozwiązań w konstrukcji budynku. Takie podejście do tematyki zastosowania materiałów w architekturze nakreśla praktyczne aspekty tworzenia przestrzeni podczas pracy np. z drewnem. Podejście przedstawiono w kontekście dziedzictwa kulturowego podczas intensywnych warsztatów dotyczących tradycji i kultury budownictwa wybranych regionów...
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Computer-Supported Polysensory Integration Technology for Educationally Handicapped Pupils
PublicationIn this paper, a multimedia system providing technology for hearing and visual attention stimulation is shortly presented. The system aims to support the development of educationally handicapped pupils. The system has been presented in the context of its configuration, architecture, and therapeutic exercise implementation issues. Results of pupils’ improvements after 8 weeks of training with the system are also provided. Training...
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Future of medicine: personalized oncology
PublicationUnderstanding genetic and epigenetic mechanisms of tumorigenesis allows identifying many vital mutations affected the formation of various malignancies. This led to the discovery of a new therapeutic approach, based on molecular mechanisms in the world of medicine, which is called personalized medicine (PM). This review aims to outline the state of the art of the personalized medicine in treatment, taking into account anti-cancer...
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LSDP_Large_Scale Development Projects 2022/23 _ MASTERPLAN LANDSCAPE PARK NECKAR
e-Learning CoursesDesign Studio working on Students' Competition: Neckar Landscape Park. Re-imagining the Productive City Region
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Simplified diffusion analysis – cartography as a tool for combating pandemics
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