Wyniki wyszukiwania dla: FACTOR STRUCTURE
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Wpływ równości nawierzchni i dynamicznego oddziaływania pojazdów ciężkich na trwałość zmęczeniową nawierzchni podatnych
PublikacjaPodczas ruchu pojazdu obserwuje się odchylenia nacisków osi pojazdów od nacisku statycznego, co jest spowodowane nierównościami nawierzchni. Dynamiczne obciążenia pojazdów w większym stopniu wytężają konstrukcję nawierzchni drogowej. Rozkład obciążeń dynamicznych ma kształt rozkładu normalnego i jest opisywany poprzez obciążenie statyczne oraz wskaźniki dynamiczne DI lub DLC. Wraz z pogorszeniem równości i zwiększeniem prędkości...
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Escherichia coli K-12 suppressor-free mutants lacking early glycosyltransferases and late acyltransferases. Minimal lipopolysaccharide structure and induction of envelope stress response.
PublikacjaTo elucidate the minimal lipopolysaccharide (LPS) structure needed for the viability of Escherichia coli, suppressor-free strains lacking either the 3-deoxy-d-manno-oct-2-ulosonic acid transferase waaA gene or derivatives of the heptosyltransferase I waaC deletion with lack of one or all late acyltransferases (lpxL/M/P) and/or various outer membrane biogenesis factors were constructed. Δ(waaC lpxL lpxM lpxP) and waaA mutants exhibited...
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Properties of water in the region between a tubulin dimer and a single motor head of kinesin
PublikacjaA kinesin is a molecular motor that can perform movement on a microtubule track in a stepping-like manner. This motion is connected with processes of association and dissociation of kinesin and tubulin. Water is an important participant in these kinds of molecular interactions. This is why we have decided to investigate the dynamical and structural properties of water in the region between the kinesin catalytic domain and the tubulin...
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Effect of Aromatic System Expansion on Crystal Structures of 1,2,5-Thia- and 1,2,5-Selenadiazoles and Their Quaternary Salts: Synthesis, Structure, and Spectroscopic Properties
PublikacjaRational manipulation of secondary bonding interactions is a crucial factor in the construction of new chalcogenadiazole-based materials. This article reports detailed experimental studies on phenanthro[9,10-c][1,2,5]chalcogenadiazolium and 2,1,3-benzochalcogenadiazolium salts and their precursors. The compounds were synthesized, characterized employing NMR and UV-Vis spectroscopy. TD-DFT calculations were also performed. The influence...
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Psychosocial risks associated with the profession of train driver
PublikacjaExcellent competencies as well as a good physical and mental health are required in train drivers’ profession. Despite the changes in the structure of employment the train drivers above 46 years and job tenure longer than 30 years are the largest group. The generation gap is becoming more pronounced, and its fulfilment will not be easy. It is related not only to training of new personnel but also promotion of healthy work environment...
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Structure and evolution of the 4-helix bundle domain of Zuotin, a J-domain protein co-chaperone of Hsp70
PublikacjaThe J-domain protein Zuotin is a multi-domain eukaryotic Hsp70 co-chaperone. Though it is primarily ribosome-associated, positioned at the exit of the 60S subunit tunnel where it promotes folding of nascent polypeptide chains, Zuotin also has off-ribosome functions. Domains of Zuotin needed for 60S association and interaction with Hsp70 are conserved in eukaryotes. However, whether the 4-helix bundle (4HB) domain is conserved remains...
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Experimental study on models of cylindrical steel tanks under mining tremors and moderate earthquakes
PublikacjaThe aim of the study is to show the results of complex shaking table experimental investigation focused on the response of two models of cylindrical steel tanks under mining tremors and moderate earthquakes, including the aspects of diagnosis of structural damage. Firstly, the impact and the sweep-sine tests have been carried out, so as to determine the dynamic properties of models filled with different levels of liquid. Then,...
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Results of tests on speech intelligibility in reverberant conditions
Dane BadawczeThe dataset contains the results of tests that aimed to provide a relationship between the rate of speech (RoS) and reverberation conditions characterized by the Speech Transmission Index (STI).
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Novel two-step synthesis method of thin film heterojunction of BiOBr/Bi2WO6 with improved visible-light-driven photocatalytic activity
PublikacjaA novel two-step ionic liquid assisted procedure was applied for a controllable synthesis of BiOBr/Bi2WO6 heterojunction thin films. The preparation route involved an anodic oxidation of tungsten foil and hydrothermal transformation of as-anodized oxide in the presence of bismuth precursor and ionic liquid, N-butylpyridinium bromide [BPy][Br]. The BiOBr plates with irregular shapes adhered to the surface of flower-like Bi2WO6 and...
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Selective adsorption of BTEX on calixarene-based molecular coordination network determined by 13C NMR spectroscopy
PublikacjaBenzene, toluene, ethylbenzene, and xylenes (BTEX), a class of volatile organic compounds, are harmful pollutants but also very important precursors in organic industrial chemistry. Among different approaches used for the BTEX treatment, the adsorption technology has been recognized as an efficient approach because it allows to recover and reuse both adsorbent and adsorbate. However, the selective adsorption of the components is...
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Analysis of effect of overloaded vehicles on fatigue life of flexible pavements based on weigh in motion (WIM) data
PublikacjaOverloaded vehicles have a significant impact on pavement fatigue life and distress. As the studies show, the phenomena intensify when the control of traffic is poor. The paper presents the results of the research including analysis of weigh in motion data from eight stations and analysis of asphalt pavement fatigue caused by mixed traffic. Distributions of vehicles axles load including the multiple axles effects are presented....
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Effect of Manual Therapy Compared to Ibuprofen on Primary Dysmenorrhea in Young Women—Concentration Assessment of C-Reactive Protein, Vascular Endothelial Growth Factor, Prostaglandins and Sex Hormones
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Solar light driven degradation of textile dye contaminants for wastewater treatment – studies of novel polycationic selenide photocatalyst and process optimization by response surface methodology desirability factor
PublikacjaThe unplanned anthropogenic activities and raced industrial revolution detrimentally causes serious threat to terrestrial and aquatic life. A high discharge of wastewater from industries using dyes affects living organisms and the environment. This paper presents studies on polycationic selenides (PCS) synthesized by hydrothermal methods for photocatalytic degradation of dyes. The synthesized PCS were confirmed by various characterization...
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Stable Field Electron Emission and Plasma Illumination from Boron and Nitrogen Co‐Doped Edge‐Rich Diamond‐Enhanced Carbon Nanowalls
PublikacjaSuperior field electron emission (FEE) characteristics are achieved in edge-rich diamond-enhanced carbon nanowalls (D-ECNWs) grown in a single-step chemical vapor deposition process co-doped with boron and nitrogen. The structure consists of sharp, highly conductive graphene edges supplied by a solid, diamond-rich bottom. The Raman and transmission electron microscopy studies reveal a hybrid nature of sp3-diamond and sp2-graphene...
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An evaluation and explanation of (in)efficiency in higher education institutions in Europe and the U.S. with the application of two-stage semi-parametric DEA
PublikacjaThis study uses data envelopment analysis (DEA) to evaluate the relative efficiency of 500 higher education institutions (HEIs) in ten European countries and the U.S. for the period between 2000 and 2010. Efficiency scores are determined using different input-output sets (inputs: total revenue, academic staff, administration staff, total number of students; outputs: total number of publications, number of scientific articles, graduates)...
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Structure and Stability Characterization of Natural Lake Pigments Made from Plant Extracts and Their Potential Application in Polymer Composites for Packaging Materials
PublikacjaNatural dyes were extracted from various plant sources and converted into lake pigments based on aluminum and tin. Three different plants (weld, Persian berries, and Brazilwood) were chosen as representative sources of natural dyes. High-performance liquid chromatography (HPLC) and triple-quadrupole mass spectrometry (QqQ MS) were used to identify dyestuffs in the raw extracts. The natural dyes and lake pigments were further characterized...
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Novel 2-alkythio-4-chloro-N-[imino(heteroaryl)methyl]benzenesulfonamide Derivatives: Synthesis, Molecular Structure, Anticancer Activity and Metabolic Stability
PublikacjaA series of novel 2-alkythio-4-chloro-N-[imino-(heteroaryl)methyl]benzenesulfonamide derivatives, 8–24, were synthesized in the reaction of the N-(benzenesulfonyl)cyanamide potassium salts 1–7 with the appropriate mercaptoheterocycles. All the synthesized compounds were evaluated for their anticancer activity in HeLa, HCT-116 and MCF-7 cell lines. The most promising compounds, 11–13, molecular hybrids containing benzenesulfonamide...
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Multicopy Suppressor Analysis of Strains Lacking Cytoplasmic Peptidyl-Prolyl cis/trans Isomerases Identifies Three New PPIase Activities in Escherichia coli That Includes the DksA Transcription Factor
PublikacjaConsistent with a role in catalyzing rate-limiting step of protein folding, removal of genes encoding cytoplasmic protein folding catalysts belonging to the family of peptidyl-prolyl cis/trans isomerases (PPIs) in Escherichia coli confers conditional lethality. To address the molecular basis of the essentiality of PPIs, a multicopy suppressor approach revealed that overexpression of genes encoding chaperones (DnaK/J and GroL/S),...
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The model homologue of the partially defective human 5,10-methylenetetrahydrofolate reductase, considered as a risk factor for stroke due to increased homocysteine level, can be protected and reactivated by heat shock proteins
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The impact of prenatal stress on insulin-like growth factor-1 and pro-inflammatory cytokine expression in the brains of adult male rats: The possible role of suppressors of cytokine signaling proteins
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Rotational Molding of Linear Low-Density Polyethylene Composites Filled with Wheat Bran
PublikacjaApplication of lignocellulosic fillers in the manufacturing of wood polymer composites (WPCs) is a very popular trend of research, however it is still rarely observed in the case of rotational molding. The present study aimed to analyze the impact of wheat bran content (from 2.5 wt.% to 20 wt.%) on the performance of rotationally-molded composites based on a linear low-density polyethylene (LLDPE) matrix. Microscopic structure...
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Chiral and achiral crystals, charge-assisted hydrogen-bond patterns and self-organization of selected solid diaminium thiosulfates
PublikacjaAbstract A series of diaminium thiosulfates, derivatives of diamines: NH2CH2CH(CH3)NH2 (1) and NH2(CH2)nNH2, n = 3-6 (2-5 respectively)and thiosulfuric acid were prepared and their structures determined by crystal X-ray diffraction analysis. Compounds 1, 2 and 4 turned out to be hydrates. The crystal structure of 1,2-proylenediaminium thiosulfate is chiral and exhibits spontaneous resolution. Crystals for both enantiomers...
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Geometry optimization of steroid sulfatase inhibitors - the influence on the free binding energy with STS
PublikacjaIn the paper we review the application of two techniques (molecular mechanics and quantum mechanics) to study the influence of geometry optimization of the steroid sulfatase inhibitors on the values of descriptors coded their chemical structure and their free binding energy with the STS protein. We selected 22 STS-inhibitors and compared their structures optimized with MM+, PM7 and DFT B3LYP/6–31++G* approaches considering separately...
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Interactions in Ternary Aqueous Solutions of NMA and Osmolytes—PARAFAC Decomposition of FTIR Spectra Series
PublikacjaIntermolecular interactions in aqueous solutions are crucial for virtually all processes in living cells. ATR-FTIR spectroscopy is a technique that allows changes caused by many types of such interactions to be registered; however, binary solutions are sometimes difficult to solve in these terms, while ternary solutions are even more difficult. Here, we present a method of data pretreatment that facilitates the use of the Parallel...
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Stability and load bearing capacity of a braced truss under upward wind loading
PublikacjaThe paper is focused on the numerical and experimental investigation of stability of a steel truss under upward wind loading. The structure was stiffened by elastic braces situated at the top and bottom chord. Usually the lateral (translational) brace stiffness is considered. However, the rotational stiffness of braces caused by interaction between torsional stiffness of the truss top chord and bending stiffness of the roof elements...
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Stability and load bearing capacity of a braced truss under upward wind loading
PublikacjaThe paper is focused on the numerical and experimental investigation of stability of a steel truss under upward wind loading. The structure was stiffened by elastic braces situated at the top and bottom chord. Usually the lateral (translational) brace stiffness is considered. However, the rotational stiffness of braces caused by interaction between torsional stiffness of the truss top chord and bending stiffness of the roof elements...
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Extending the Frequency Limit of Microstrip-Coupled CSRR Using Asymmetry
PublikacjaAbstract— This article explains the frequency limitation in designing microstrip circuits based on a complementary split-ring resonator (CSRR) and reports a novel technique for increasing its operating frequency, which makes the CSRR suitable for high-frequency applications. This study helps in synthesizing the dimensions of symmetric CSRR (SCSRR) and asymmetric CSRR (ACSRR) circuits, which shows the applicability of the proposed...
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Evaluation of Pavement Temperatures in Poland During Winter Conditions
PublikacjaThe paper presents the analysis of pavement temperatures from meteorological stations located at the Polish national roads during the impact of low winter temperatures. Presented issue is particularly important in view of the problem of low-temperature cracks that occur in the asphalt pavement under the influence of low temperatures. For each location of meteorological station there were analysed measurements of the temperature...
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Hydration of Simple Model Peptides in Aqueous Osmolyte Solutions
PublikacjaThe biology and chemistry of proteins and peptides are inextricably linked with water as the solvent. The reason for the high stability of some proteins or uncontrolled aggregation of others may be hidden in the properties of their hydration water. In this study, we investigated the effect of stabilizing osmolyte–TMAO (trimethylamine N-oxide) and destabilizing osmolyte–urea on hydration shells of two short peptides, NAGMA (N-acetyl-glycine-methylamide)...
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High-performance graphene-based biosensor using a metasurface of asymmetric silicon disks
PublikacjaIn recent years, optical biosensors widely applicable for medical applications, have received much attention. In this paper, we propose a high-performance polarization-insensitive optical biosensor based on a graphene-dielectric metasurface. The metasurface consists of an asymmetric dielectric disk array that supports a high Q-factor Fano resonance. The provided sharp Fano resonance results in an enhanced light-matter interaction...
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Copper Slag as a Potential Waste Filler for Polyethylene-Based Composites Manufacturing
PublikacjaThe present study aimed to analyze the application of waste material from copper production– copper slag (ŻŻL) as filler for composites based on the high-density polyethylene (HDPE). Copper slag filler was introduced in the amounts of 1–20 wt%, and its influence on the appearance (color analysis), chemical structure (Fourier-transform infrared (FTIR) spectroscopy), microstructure (optical microscopy), as well as static (tensile...
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Damage Imaging in Lamb Wave-Based Inspection of Adhesive Joints
PublikacjaAdhesive bonding has become increasingly important in many industries. Non-destructive inspection of adhesive joints is essential for the condition assessment and maintenance of a structure containing such joints. The aim of this paper was the experimental investigation of the damage identification of a single lap adhesive joint of metal plate-like structures. Nine joints with different defects in the form of partial debonding...
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Properties of ordered titanium templates covered with Au thin films for SERS applications
PublikacjatCurrently, roughened metal nanostructures are widely studied as highly sensitive Raman scattering sub-strates that show application potential in biochemistry, food safety or medical diagnostic. In this workthe structural properties and the enhancement effect due to surface enhanced Raman scattering (SERS) ofhighly ordered nano-patterned titanium templates covered with thin (5–20 nm) gold films are reported.The templates are formed...
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Reactive imines: Addition of 2-aminopyrimidine to the imine bond and isolation of the aminal from the equilibrium mixture aminal/imine
PublikacjaThe reaction between o-vanillin and 2-aminopyrimidine leads to the formation of a single crystalline product: aminal, 1, which results from the reaction of the initially formed imine with 2-aminopyrimidine. The reaction was followed by the NMR spectroscopy. VT NMR studies prove that in solution two major species are observed: aminal and imine and their ratio depends on the time or/and temperature with the imine content increasing...
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PSYCHOMETRIC PROPERTIES OF THE POLISH VERSION OF THE GENERALIZED ANXIETY DISORDER 7-ITEM SCALE (GAD-7) IN A NON-CLINICAL SAMPLE OF EMPLOYEES DURING PANDEMIC CRISIS
PublikacjaObjectives: The COVID-19 outbreak is an example of a crisis that triggered an increase in generalized anxiety disorder. The study aims to validate the Polish version of the Generalized Anxiety Disorder 7-item scale (GAD-7) by Spitzer et al. among a non-clinical sample of employees and examine the invariance depending on the gender and age of working adults. Material and Methods: For assessing factor structure of the Polish version...
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Prediction of Overall In Vitro Microsomal Stability of Drug Candidates Based on Molecular Modeling and Support Vector Machines. Case Study of Novel Arylpiperazines Derivatives
PublikacjaOther than efficacy of interaction with the molecular target, metabolic stability is the primary factor responsible for the failure or success of a compound in the drug development pipeline. The ideal drug candidate should be stable enough to reach its therapeutic site of action. Despite many recent excellent achievements in the field of computational methods supporting drug metabolism studies, a well-recognized procedure to model...
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Modyfikacja kompozytów elastomerowych NR za pomocą ligniny i glicerolizatu
PublikacjaPrzedmiotem opisanych w niniejszym artykule badań są wulkanizaty kauczuku naturalnego. Celem pracy było zbadanie wpływu ligniny oraz glicerolizatu na wybrane właściwości kompozytów zawierających kauczuk naturalny. Strukturę chemiczną przygotowanych materiałów potwierdzono, wykorzystując analizę spektroskopową w podczerwieni (FTIR). Zbadano również właściwości mechaniczne przy statycznym rozciąganiu, twardość, ścieralność oraz odbojność...
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Interfacial water controls the process of adsorption of hyperactive antifreeze proteins onto the ice surface
PublikacjaA mechanism of interactions between the ice-binding surface of a hyperactive antifreeze protein molecule and the ice surface is proposed, involving the influence of water present between the two surfaces on the behavior of the approaching molecule. It is demonstrated that the interfacial water, even before its full solidification, can act as a factor that pushes away or pulls nearer the protein molecule to ensure its proper positioning....
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Variable Fractional Delay Filter Design Using a Symmetric Window
PublikacjaIn this paper a numerically efficient method for designing a nearly optimal variable fractional delay (VFD) filter based on a simple and well-known window method is presented. In the proposed method a single window extracted from the optimal filter with fixed fractional delay (FD) is divided into even and odd part. Subsequently, the odd part is discarded and symmetric even part of the extracted window is used to design a family...
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Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
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Molecular basis of lipopolysaccharide heterogeneity in Escherichia coli: envelope stress-responsive regulators control the incorporation of glycoforms with a third 3-deoxy-α-D-manno-oct-2-ulosonic acid and rhamnose.
PublikacjaMass spectrometric analyses of lipopolysaccharide (LPS) from isogenic Escherichia coli strains with nonpolar mutations in the waa locus or overexpression of their cognate genes revealed that waaZ and waaS are the structural genes required for the incorporation of the third 3-deoxy-α-D-manno-oct-2-ulosonic acid (Kdo) linked to Kdo disaccharide and rhamnose, respectively. The incorporation of rhamnose requires prior sequential incorporation...
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Study of the Resistance to Influence of Aggressive Liquids on Concrete with Lightweight Aggregate
PublikacjaThe corrosion of the structure of concrete caused by the aggressive external environment is one of the main problems that can reduce the durability of buildings. The paper analyzes the influence of the type of component on selected properties of lightweight concrete (LWC) exposed to aggressive liquids. When lightweight concrete containing porous aggregates is used, the influence of an aggressive environment may be of particular...
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Corrosion Inhibition Mechanism and Efficiency Differentiation of Dihydroxybenzene Isomers Towards Aluminum Alloy 5754 in Alkaline Media
PublikacjaThe selection of efficient corrosion inhibitors requires detailed knowledge regarding the interaction mechanism, which depends on the type and amount of functional groups within the inhibitor molecule. The position of functional groups between different isomers is often overlooked, but is no less important, since factors like steric hinderance may significantly affect the adsorption mechanism. In this study, we have presented how...
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Biocompatibility and potential functionality of lanthanum-substituted cobalt ferrite spinels
PublikacjaBulk and nanostructurized lanthanum-cobalt spinels have attracted a lot of interest from researchers, due to their unique physical and chemical properties as well as functionalities, which are interesting for biomedical and electronic industries. In this manuscript we show that introducing small lanthanum (La3+) content can tune magnetic, electronic and cytotoxic properties of the CoFe2− xLaxO4 system (x ≤ 0.1). The mechanisms...
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A methodology for ultimate strength assessment of ship hull girder accounting for enhanced corrosion degradation modelling
PublikacjaThe presented work shows a methodology for the ultimate strength assessment of a ship hull, considering enhanced corrosion modelling. The approach is based on the classical Smith method. However, the recent findings regarding the impact of corrosion degradation on ultimate strength are incorporated. To this end, the stress–strain relationships for particular elements composing ship hull cross-section are modified using a specially...
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The potential of imogolite nanotubes as (co-)photocatalysts: a linear-scaling density functional theory study
PublikacjaWe report a linear-scaling density functional theory (DFT) study of the structure, wall-polarization absolute band-alignment and optical absorption of several, recently synthesized, open-ended imogolite (Imo) nanotubes (NTs), namely single-walled (SW) aluminosilicate (AlSi), SW aluminogermanate (AlGe), SW methylated aluminosilicate (AlSi-Me), and double-walled (DW) AlGe NTs. Simulations with three different semi-local and dispersion-corrected...
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Investigation and operation problems of metal tanks in Poland
PublikacjaThe paper consists of three parts concerned with steel cylindrical, vertical tank for liquid fuel. In the first part the present trends in tank design and building in Poland are described. The main are: · reduction of environment contamination danger caused by tank leakage and hydrocarbons evaporation, · increasing capacity of new tanks (100000 m3 and more) due to economic factor - reduction of steel amount per m3 of storage capacity....
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Ion conduction in beryllium-alumino-silicate glasses doped with sodium or sodium and lithium ions
PublikacjaElectrical properties of beryllium-alumino-silicate glasses containing sodium ions or sodium and lithium ions were studied with impedance spectroscopy technique over a frequency range from 10 mHz to 1 MHz and at temperature range from 213 to 473 K. The frequency- and temperature-dependent conductivity spectra of individual single alkali glasses were superimposed by means of the Summerfield scaling. Mixed-alkali glasses do not overlap...
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Correction: Profiles of a broad spectrum of epigenetic DNA modifications in normal and malignant human cell lines: Proliferation rate is not the major factor responsible for the 5-hydroxymethyl-2′-deoxycytidine level in cultured cancerous cell lines
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In-tube extraction for the determination of the main volatile compounds in Physalis peruviana L
PublikacjaAn analytical procedure based on in-tube extraction followed by gas chromatography with mass spectrometry has been developed for the analysis of 24 main volatile components in cape gooseberry (Physalis peruviana L.) samples. According to their chemical structure, the compounds were organized into different groups: one hydrocarbon, one aldehyde, four alcohols, four esters, and 14 monoterpenes. By single-factor experiments, incubation...