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Wyniki wyszukiwania dla: TRIPLE HELIX
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Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma
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Bacteriophages as potential tools for use in antimicrobial therapy and vaccine development
PublikacjaThe constantly growing number of people suffering from bacterial, viral, or fungal infections, parasitic diseases, and cancers prompts the search for innovative methods of disease prevention and treatment, especially based on vaccines and targeted therapy. An additional problem is the global threat to humanity resulting from the increasing resistance of bacteria to commonly used antibiotics. Conventional vaccines based on bacteria...
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Study on polymer modified road asphalt mixture
PublikacjaThe formulation of ternary asphalt-additives blend composed of crumb rubber : low-density polyethylene (CR : LDPE) and crumb rubber : textile fiber (CR : TF) couples, and quaternary asphalt additives-blend composed of (CR : LDPE : TF) triplets on the virgin asphalt to optimize the asphalt basic and rheological properties and to use the extrusion process of two or three additives to obtain composite materials of them, as well as...
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Testing of Software for the Planning of a Linear Object GNSS Measurement Campaign under Simulated Conditions
PublikacjaThe precision of a linear object measurement using satellite techniques is determined by the number and the relative position of the visible satellites by the receiver. The status of the visible constellation is described by DOP. The obtained geometric coefficient values are dependent on many variables. When determining these values, field obstacles at the receiver location and satellite positions changing with time must be taken...
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Drug-Eluting Biopsy Needle as a Novel Strategy for Antimicrobial Prophylaxis in Transrectal Prostate Biopsy
PublikacjaOBJECTIVES: To preclinically evaluate drug-eluting biopsy needles (patent pending WO2016118026) as a new potential way of antimicrobial prophylaxis for transrectal prostate biopsy. METHODS: Twenty steel biopsy needles have been coated with polyvinyl alcohol, ciprofloxacin, and amikacin. Modified biopsy needles have been randomly divided into 3 groups (1:2:1 ratio). Needles from group I were immersed for 30 minutes in dedicated...
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Shooting Gas Cylinders to Prevent Their Explosion in Fire
PublikacjaGas cylinders in general, and particularly cylinders containing acetylene, constitute a great potential danger to fire and rescue services involved in salvage operations. Experiments show that gas cylinders with acetylene, oxygen, hydrogen, CNG, LPG or CO2 may blow after short exposition to heat with very destructive effect as fragments of blown cylinder may fly even several hundred meters. In the case of acetylene the explosion...
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Distinctive facades of commercial buildings and the quality of public space,
PublikacjaMutual relations between the retail center and public spaces of the city are varied. They depend on the type and size of the commercial structure. Other ones are for multifunctional shopping centers and other for high streets. In megastores and shopping malls the essential for their functioning is their interior and entrance, which is sometimes the only place of interpenetration of the commercial structure with the surrounding...
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An adaptive-noise Augmented Kalman Filter approach for input-state estimation in structural dynamics
PublikacjaThe establishment of a Digital Twin of an operating engineered system can increase the potency of Structural Health Monitoring (SHM) tools, which are then bestowed with enhanced predictive capabilities. This is particularly relevant for wind energy infrastructures, where the definition of remaining useful life is a main driver for assessing the efficacy of these systems. In order to ensure a proper representation of the physical...
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‘The Urban Walk Architecture Talk’— Bridging Socially Engaged Art, Urban Processes and Cultural Development
Publikacja“Urban Walk—Architecture Talk” is a project based on an elective seminar under the same title organized at the Faculty of Architecture of Gdańsk University of Technology. It aims at getting familiar with the topic of multi-layer and multi-sensory reception of public space, mainly by recognizing the needs of its users. Additionally, it deals with the consequences of such perception and the use of space in order to build more complete...
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Chemical characterization of wild populations of Brassica oleracea complex species (n=9) for the content of their bioactive compounds
PublikacjaThe wild species belonging to Brassica oleracea complex species (n=9) are widespread in the Mediterranean basin and represent the relative species of several vegetable crops, such as broccoli, cauliflower, kale, cabbage. They are characterized by the high level of bioactive compounds, such as glucosinolates (GLSs), known for their benefits for human health. Four accessions were evaluated: B. macrocarpa (BM) from Favignana (Trapani),...
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Stereo vision with Equal Baseline Multiple Camera Set (EBMCS) for obtaining depth maps of plants
PublikacjaThis paper presents a method of improving the estimation of distances between an autonomous harvesting robot and plants with ripe fruits by using the vision system based on five cameras. The system is called Equal Baseline Multiple Camera Set (EBMCS). EBMCS has some features of a camera matrix and a camera array. EBMCS is regarded as a set of stereo cameras for estimating distances by obtaining disparity maps and depth maps. This...
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Comparative Analysis of Phytochemical Profiles and Selected Biological Activities of Various Morphological Parts of Ligustrum vulgare
PublikacjaLigustrum vulgare (LV), widely cultivated in Europe and often used in hedges, has been histori-cally recognized in folk medicine for its potential health benefits. This study focused on exploring the untargeted identification of secondary metabolites in ethanol extracts (70% v/v) from differ-ent morphological parts (young shoots, leaves, flowers and fruits) of LV at various stages of plant development, using ultra-high-performance...
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Proportional-Derivative and Model-Based Controllers for Control of a Variable Mass Manipulator
PublikacjaIn the paper, numerical analysis of dynamics of a variable mass manipulator is presented. A revolute joints composed manipulator is considered. Payload of the gripper is considered as the only element characterized by unknown value of its mass (variable between subsequent operations). As in other cases of the revolute joints composed manipulators, its behaviour dependents significantly on the pose of the manipulator. When the manipulator...
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Cold recycled mixtures for binder courses - laboratory evaluation of mechanical properties
PublikacjaCold recycled mixtures composed with cement and bituminous emulsion are nowadays commonly used material for base layer. Typical pavement with cold recycled mixtures usually consists of two asphalt courses (wearing and binding course) constructed over cold recycled base. Therefore the next step in cold recycling is possibility of design of binding courses with recycled materials, but with potential to obtain high quality mixtures...
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Antitumor DNA-Damaging C-1748 is a New Inhibitor of Autophagy that Triggers Apoptosis in Human Pancreatic Cancer Cell Lines
PublikacjaDespite the enormous progress that has been made over the past decades in diagnosis, treatment and prevention of many types of tumors, survival rates in pancreatic cancer still remain poor. Pancreatic cancer is one of the most malignant and chemoresistant tumors and the profound mechanism supporting these phenomena is the constitutively activated prosurvival autophagy. The antitumor 1-nitroacridine derivative C-1748 belongs to...
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Mechanika kontaktu w charakteryzowaniu materiałów inżynierskich
PublikacjaW pierwszej części pracy przedstawiono teoretyczne podstawy mechaniki kontaktu. Omówiono model kontaktu Hertza opisujący zależność pomiędzy obciążeniem przyłożonym do kulistego wgłębnika i jego przemieszczeniem. W dalszej części scharakteryzowano modele niehertzowskie, w których pod uwagę bierze się siły adhezji. Przedstawiono dwa modele uwzględniające adhezyjne przyciąganie sferycznego wgłębnika i podłoża, tj. model Johnsona,...
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Analiza i badania pomiarowe dokładności lokalizowania terminali ruchomych w sieciach komórkowych
PublikacjaJakość oferowanych przez operatorów sieci komórkowych usług o wartości wzbogaconej (usług dodanych) zależy od efektywności metod estymacji położenia geograficznego terminala ruchomego MS (Mobile Station). Dokładność istniejących w sieciach komórkowych metod lokalizacyjnych jest niewystarczająca, szczególnie w odniesieniu do usług związanych z wywołaniem w niebezpieczeństwie. Obecnie, do najbardziej popularnej w sieciach komórkowych...
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The health impact of urban parks along waterways
PublikacjaWell designed parks along waterways could promote health and well-being of local inhabitants. The way the human settlements meet water bodies can influence the habits of local population. How people spend their time have significant impact on their health. For example, a team of Japanese scientists has proven that a well designed walk-able green spaces are crucial for the longevity of elderly citizens (Takano T. et al, 2002). Nature...
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State-of-the-art framework for high-speed camera and photogrammetric use in geometry evaluation of prestressed concrete failure process
PublikacjaPrestressed structures are a key to the realization of the boldest architectural ideas, regardless of shape complexity, great height and large span. A characteristic feature of the prestressed structure is the better use of concrete material properties by insertion of internal forces. The internal forces are opposed to external loads effects (forces and deformations of structure). Prestressed reinforced concrete beams are characterized...
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Sopot - is it possible to retain the unique image of the city?
PublikacjaSopot is the best-known seaside resort in Poland. The city is unique with regard not only to its location and natural values, but also its interesting architecture, which dates back to the end of the 19th and the beginning of the 20th century. The relic of that era is the largest in the country number of buildings characteristic for the Northern European seaside resorts. The architecture of historic Sopot is dominated by eclectic...
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Employee Well-Being and its Potential Link With Human Knowledge Risks
PublikacjaEmployee well-being is an essential component of any organisation organisation. Conscious companies make every effort to create a healthy work environment. The well-being of employees and their overall emotional, physical and economic health is affected by various internal and external factors. When employees feel well, they tend to perform better. Therefore, the impact of employee well-being on the organisation is a fact and has...
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The evidence for the impact of policy on physical activity outcomes within the school setting: A systematic review
PublikacjaPurpose Despite the well-established health benefits of physical activity (PA) for young people (aged 4–19 years), most do not meet PA guidelines. Policies that support PA in schools may be promising, but their impact on PA behavior is poorly understood. The aim of this systematic review is to ascertain the level and type of evidence reported in the international scientific literature for policies within the school setting that...
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Tworzenie miasta przyjaznego wszystkim
PublikacjaTworzenie miasta przyjaznego wszystkim, to zadnie, które jest prawdopodobnie celem wszystkich włodarzy miejskich. Czy nie jest tak, że każdy chciałby w takim mieście zamiesz-kać? Jednak zadanie to jest dość trudne, bo wymaga pogodzenia wielu aspektów życia mieszkańców. Obecnie do zagadnień środowiskowych związanych z szeroko rozumianą ekologią dochodzi zagadnienie dostosowania przestrzeni zgodnie z zasadami projektowania uniwersalnego....
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DNA-reactive anticancer imidazoacridinone C-1311 is a new inhibitor of hypoxia-inducible factor 1 alpha, vascular endothelial growth factor and tumor angiogenesis
PublikacjaHypoxia-inducible factor 1 (HIF-1) plays a critical role for tumor adaptation to hypoxia and promotes angiogenesis. Antitumor imidazoacridinone C-1311 is a DNA reactive topoisomerase II and FLT3 receptor tyrosine kinase inhibitor selected for phase II clinical trials for breast cancer. Here, we demonstrate the new mechanism of C-1311 action involving HIF-1a, vascular endothelial growth factor (VEGF) and angiogenesis as additional...
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Asymmetric Renyi Problem and > PATRICIA Tries
PublikacjaIn 1960 R´enyi asked for the number of random queries necessary to recover a hidden bijective labeling of n distinct objects. In each query one selects a random subset of labels and asks, what is the set of objects that have theselabels? Weconsider here anasymmetric version of the problem in which in every query an object is chosenwith probability p > 1/2 and we ignore “inconclusive” queries. We study the number of queries needed...
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Types of Markov Fields and Tilings
PublikacjaThe method of types is one of the most popular techniques in information theory and combinatorics. However, thus far the method has been mostly applied to one-dimensional Markov processes, and it has not been thoroughly studied for general Markov fields. Markov fields over a finite alphabet of size m ≥ 2 can be viewed as models for multi-dimensional systems with local interactions. The locality of these interactions is represented...
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Removal of selected sulfonamides and sulfonamide resistance genes from wastewater in full-scale constructed wetlands
PublikacjaSulfonamides are high-consumption antibiotics that reach the aquatic environment. The threat related to their presence in wastewater and the environment is not only associated with their antibacterial properties, but also with risk of the spread of drug resistance in bacteria. Therefore, the aim of this work was to evaluate the occurrence of eight commonly used sulfonamides, sulfonamide resistance genes (sul1–3) and integrase genes...
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Ogród muz II
Publikacja"Gdańsk nowożytny a świat antyczny" – to tytuł drugiego tomu publikacji stanowiącej zapis projektu "W nadbałtyckim ogrodzie muz…", zorganizowanego w roku 2015 przez PAN Bibliotekę Gdańską i Katedrę Filologii Klasycznej Uniwersytetu Gdańskiego. W tomie pierwszym, wydanym w 2016 roku pod tytułem W gdańskim ogrodzie muz, obok podstawowych dla recepcji kultury grecko-rzymskiej sfer ekspresji, jaką jest poezja i sztuka perswazji,...
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Gdańsk nowożytny a świat antyczny
Publikacja"Gdańsk nowożytny a świat antyczny" – to tytuł drugiego tomu publikacji stanowiącej zapis projektu "W nadbałtyckim ogrodzie muz…", zorganizowanego w roku 2015 przez PAN Bibliotekę Gdańską i Katedrę Filologii Klasycznej Uniwersytetu Gdańskiego. W tomie pierwszym, wydanym w 2016 roku pod tytułem W gdańskim ogrodzie muz, obok podstawowych dla recepcji kultury grecko-rzymskiej sfer ekspresji, jaką jest poezja i sztuka perswazji,...
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THE STUDY OF WATER POLLUTION OF THE LOWER VISTULA RIVER BY PLASTIC PARTICLES
PublikacjaSince the beginning of widespread use of plastic its consumption and production has been constantly increasing. As a result of human activity part of waste ends up in our environment and is deposited in each of the elements of the biosphere. These impurities can be in the form of large elements, small particles fragmented to macroscopic level (pellets, facial scrub grains) and the microparticles visible under a microscope. Particularly...
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Direct design of Controlled Modulus Columns (CMC) based on in-situ testing
PublikacjaIn this paper, the serviceability limit state and bearing capacity of tension screw displacement piles were analyzed using the results of static pile load tests, carried out on the test plot near the Elbląg city, and field, and laboratory tests. The paper presents the methodology of determining the pile load-settlement curve using different types of t-z transfer functions. The new method of constructing the pile load-settlement...
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A city is not a tree: a multi-city study on street network and urban life
PublikacjaChristopher Alexander, a British-American scholar, differentiated an old (natural) city from a new (planned) one by structure. The former resembles a “semilattice”, or a complex system encompassing many interconnected sub-systems. The latter is shaped in a graph-theoretical “tree”, which lacks the structural complexity as its sub-systems are compartmentalized into a single hierarchy. This structural distinction explains why, or...
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Aktywność przeciwgrzybowa koniugatów inhibitorów enzymatycznych z nośnikami peptydowymi
PublikacjaCelem badań przedstawionych w rozprawie było określenie aktywności przeciwgrzybowej szeregu związków będących koniugatami peptydów z inhibitorami enzymatycznymi (FMDP, cispentacyna). Zakres badań obejmował zbadanie aktywności peptydów-FMDP, CPP oraz FMDP-CPP wobec grzybów z rodzaju Candida w różnego typu podłożach, określenie możliwości powstawania oporności na FMDP-CPP i peptydy-FMDP, a także określenie szybkości transportu i...
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2018 Practice Guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension
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2018 Practice guidelines for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension
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2018 ESC/ESH Guidelines for the management of arterial hypertension
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2018 ESC/ESH Guidelines for the management of arterial hypertension
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International Expert Consensus Statement
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The Shadow of God in the Garden of the Philosopher. The Parc de La Villette in Paris in the Context of Philosophy of Chôra. Part I-V
PublikacjaThe book Shadow of God in the Philosopher's Garden. Parcde La Villette in Paris in the context of the philosophy of chôra presents the philosophical discussions that accompanied the design of the extensive park in the Parisian district of La Villette. The core of the park's theoretical framework were texts by Bernard Tschumi, in which he questioned the traditional ways of creating...
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Human and Methodological Sources of Variability in the Measurement of Urinary 8-Oxo-7,8-dihydro-2′-deoxyguanosine
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Development of Biocompatible Fe3O4@SiO2 Nanoparticles as Subcellular Delivery Platform for Glucosamine-6-phosphate Synthase Inhibitors
PublikacjaNumerous inhibitors of glucoseamine-6-phophate synthase (GlcN-6-P), the enzyme responsible from catalysis of the first step of metabolic pathway leading to metabolism 5’-diphospho-N-acetyl-D- glucosamine, were reported as effective agents for inhibiting the growth of various fungal pathogens. Among the reported inhibitors,...
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Psychometric Properties and Correlates of Precarious Manhood Beliefs in 62 Nations
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2018 ESC/ESH Guidelines for the management of arterial hypertension
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Gendered Self-Views Across 62 Countries: A Test of Competing Models
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A European Multi Lake Survey dataset of environmental variables, phytoplankton pigments and cyanotoxins
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18th European Symposium on Radiopharmacy and Radiopharmaceuticals
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Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
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Correction to: Two years later: Is the SARS-CoV-2 pandemic still having an impact on emergency surgery? An international cross-sectional survey among WSES members
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Considerations and consequences of allowing DNA sequence data as types of fungal taxa
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Global wealth disparities drive adherence to COVID-safe pathways in head and neck cancer surgery
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