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Wyniki wyszukiwania dla: INVERSE AGONIST
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Low-Cost Modeling of Microwave Components by Means of Two-Stage Inverse/Forward Surrogates and Domain Confinement
PublikacjaFull-wave electromagnetic (EM) analysis is one of the most important tools in the design of modern microwave components and systems. EM simulation permits reliable evaluation of circuits at the presence of cross-coupling effects or substrate anisotropy, as well as for accounting for interactions with the immediate environment. However, repetitive analyses required by EM-driven procedures, such as parametric optimization or statistical...
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Inverse Analysis as a Key Element of Safety Assessment under the Snow Load For The Large Suspension Roofs Structure
PublikacjaThe paper presents a concept and realization of monitoring system for the Silesian Stadium in Chorzow. The idea of the system lies in fusion of structure monitoring with a calibrated numerical FEM model [1]. The inverse problem is solved. On the base of measured selected displacements, the numerical FEM model of the structure combined with iterative method, develops the current snow load distribution. Knowing the load, we can calculate...
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Convenient Synthesis of Functionalized Unsymmetrical Vinyl Disulfides and Their Inverse Electron-Demand Hetero-Diels-Alder Reaction
PublikacjaThe simple, convenient, and efficient methods for the preparation of unsymmetrical vinyl disulfides with additional functional groups under mild conditions with moderate to high yields were designed. The developed methods include the reaction of S-vinyl phosphorodithioate with thiotosylates or S-vinyl thiotosylate with thiols. The designed methods allow for the synthesis of unsymmetrical vinyl disulfides with additional functionalities...
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Rapid Design Centering of Multi-Band Antennas Using Knowledge-Based Inverse Models and Response Features
PublikacjaAccounting for manufacturing tolerances as well as uncertainties concerning operating conditions and material parameters is one of the important yet often neglected aspects of antenna development. Appropriate quantification of uncertainties allows for estimating the fabrication yield but also to carry out robust design (e.g., yield maximization). For reliability reasons, statistical analysis should be executed at the accuracy level...
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Mutual Coupling Reduction in Antenna Arrays Using Artificial Intelligence Approach and Inverse Neural Network Surrogates
PublikacjaThis paper presents a novel approach to reduce undesirable coupling in antenna arrays using custom-designed resonators and inverse surrogate modeling. To illustrate the concept, two stand-ard patch antenna cells with 0.07λ edge-to-edge distance are designed and fabricated to operate at 2.45 GHz. A stepped-impedance resonator is applied between the antennas to suppress their mutual coupling. For the first time, the optimum values...
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Assessment of tensile forces in Sopot Forest Opera membrane by in situ measurements and iterative numerical strategy for inverse problem
PublikacjaAssessment of tensile forces in newly build Sopot Forest Opera roofing membrane is presented. The procedure is based on in situ measurements and solution of the inverse problem by an iterative procedure. The goal of the analysis is to determine whether the stress state of the membrane is consistent with the design assumptions. The paper contains the description of measurements, used instruments, applied loadings, numerical investiga-tions...
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Inverse method for axisymmetric and blade-to-blade viscous flow models in cylindrical coordinates using stream-function transformation
PublikacjaZaproponowano nową metodę odwrotną rozwiązywania dwuwymiarowych zagadnień projektowych we współrzędnych cylindrycznych. Użyto współrzędnych funkcji prądu uzależniając kształt opływanej geometrii od kształtu linii prądu. Metodę zwalidowano. Pokazano zastosowanie do przepływów osiowosymetrycznych jak i na powierzchniach cylindrycnych.
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Global EM-Driven Optimization of Multi-Band Antennas Using Knowledge-Based Inverse Response-Feature Surrogates
PublikacjaElectromagnetic simulation tools have been playing an increasing role in the design of contemporary antenna structures. The employment of electromagnetic analysis ensures reliability of evaluating antenna characteristics but also incurs considerable computational expenses whenever massive simulations are involved (e.g., parametric optimization, uncertainty quantification). This high cost is the most serious bottleneck of simulation-driven...
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New clicked full agonists of the estrogen receptor β
PublikacjaA click chemistry approach was used to synthesize a series of 1,4-diaryl-substituted 1,2,3-triazoles designed to behave as estrogen receptor (ER) ligands. We studied their affinities for both receptors α and β, their agonist activities in a cell-based luciferase reporter assay and their effect on the proliferation of the hormone-dependent MCF-7 cell line. We found two compounds (3a and 3c) that behave as selective full agonists...
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RSN reverse converter based on core function
Publikacjazaprezentowano nową architekturę konwertera z systemu resztowego do systemu binarnego opartego na funkcji jądra dla modułów 5-bitowego. Zastosowano niekrytyczną funkcję jądra.Obliczanie funkcji jądra jest realizowane przy użyciu chińskiego twierdzenia dla funkcji jądra (CRTCF). Założono także, że jeden z modułów jest potegą 2. Architektura ta umożliwia zmniejszenie złożoności sprzętowej o ok. 12.5% w porównaniu z innymi architekturami...
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Hybrid Obfuscation Technique for Reverse Engineering Problems
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Podglądanie Wszechświata [Peeping the Universe] by Michał Heller
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Adverse Renal Effects of Anticancer Immunotherapy: A Review
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Adverse Renal Effects of Anticancer Immunotherapy: A Review
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Design of reverse curves adapted to the satellite measurements
PublikacjaThe paper presents a new method for designing railway route in the direction change area adapted to the Mobile Satellite Measurements technique. The method may be particularly useful in the situations when both tangents cannot be connected in an elementary way using a circular arc with transition curves. Thus, the only solution would be the application of two circular arcs of opposite curvature signs, that is, the use of an inverse...
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Impact of adverse winter weather on traffic flow
PublikacjaThe paper aims to analyse the impact of adverse weather in winter on traffic flow using data from a dual carriageway section of an express road located in Gdansk. For the purposes of the analysis, traffic and meteorological data were collected for a period of 15 months in 2014-2015 and aggregated to 5 minutes intervals. The impact of winter weather conditions on traffic flow was assessed by comparing aggregated traffic stream parameters...
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Multipulse inverter structures with low voltage distortion
PublikacjaA novel approach to the voltage source inverters (VSI) construction is presented in the paper. The invented inverter structures allow to operate several DC/AC converters in parallel resulting in lower voltage distortions at extremely low switching frequency. The research presented in the paper describes such a parallel operation of the VSI’s which is possible thanks to the use of coupled inductors. The eighteen-pulse three-level...
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Electric motor drive with inverter output filter
PublikacjaPrzedstawiono zagadnienie sterowania i estymacji w układzie napędowym z silnikiem indukcyjnym i filtrem sinusoidalnym.Filtr użyty jest do wygładzenia prądu i napięcia silnika. Filtr wprowadza spadek napięcia i przesunięcie fazowe prądów i napięć uniemożliwiające stosowane bezczujnikowych metod sterowania wektorowego. Rozwiązaniem jest uwzględnienie filtru w sterowaniu i estymacji. Artykuł pokazuje takie rozwiązanie dla metody sterowania...
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A comprehensive approach to double inverted pendulum modelling
PublikacjaThe problem of mathematical modelling and indication of properties of a DIP has been investigated in this paper. The aim of this work is to aggregate the knowledge on a DIP modelling using the Euler-Lagrange formalism in the presence of external forces and friction. To indicate the main properties important for simulation, model parameters identification and control system synthesis, analytical and numerical tools have been used....
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Integrated Three-Level Dual-Phase Inverter
PublikacjaIn view of reducing the number of inverter legs that provide dual-phase, three-level output voltages (as may be needed in an uninterruptible power supply), and that also provide a wide range of output frequencies (as needed in an advanced motor drive system with wide speed ranges), a three-level, dual-phase inverter topology is presented in this paper. Its three-level attribute was based on the F-type inverter topological concept,...
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Predictive Current Control of Voltage-Source Inverter.
PublikacjaW artykule przedstawiono regulator prądu stojana silnika asynchronicznego z predykcją napiecia wyjściowego. Rozważono aspekty praktycznej realizacji algorytmu w układzie z procesorem sygnałowym związane z opóźnieniami pomiaru prądu przy zastosowaniu przetwornika A/C. Układ zrealizowano praktycznie przy wykorzystaniu układu FPGA. W pracy zamieszczono wyniki badań symulacyjnychi eksperymentalnych.
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Three-dimensional geographically weighted inverse regression (3GWR) model for satellite derived bathymetry using Sentinel-2 observations
PublikacjaCurrent trends of development of satellite derived bathymetry (SDB) models rely on applying calibration techniques including analytical approaches, neuro-fuzzy systems, regression optimization and others. In most of the cases, the SDB models are calibrated and verified for test sites, that provide favourable conditions for the remote derivation of bathymetry such as high water clarity, homogenous bottom type, low amount of sediment...
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Furanocoumarins in anticancer therapy – For and against
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ECONOMIC MEASURES AGAINST A PANDEMICS
PublikacjaThe appropriate level of treatment during periods of increasing workload in the health care system or a particular hospital is ensured either by changing the organization of the system and the principles of use of resources such as space, staff and consumables or their redistribution, or by financial resources such resources are increased or replenished. This article contributes to improve the concept of resource allocation as...
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Pertussis outbreak in Polish shooters with adverse event analysis
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Computer simulation of induction heating system with series inverter
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Barriers to the Development of Creative Industries in Culturally Diverse Region
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Variable Speed AC Drives with Inverter Output Filters
PublikacjaThe advance of variable speed drives systems (VSDs) engineering highlights the need of specific technical guidance provision by electrical machines and drives manufacturers, so that such applications can be properly designed to present advantages in terms of both energy efficiency and expenditure. This book presents problems and solutions related to inverter-fed electrical motors. Practically orientated, the book describes the...
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Comprehensive distortion compensation of grid-connected inverter currents
PublikacjaThe paper presents a comprehensive approach to the compensation of phase current distortion of grid-connected power inverters. Four different sources of current distortion are addressed: imperfect grid synchronization caused by the distortion in the grid voltages, voltage fluctuations in the dc link, time delays in the estimation of grid voltages, and the distortion of inverter output voltages due to dead-time effects and related...
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A Five-Leg Three-Level Dual-Output Inverter
PublikacjaClassical 3-level dual-output inverter, 3-L DOI, involves two similar 3-level inverters that provides a pair of 3-phase output voltages with same or different frequencies from common input voltage source. Flexibility of either operation of the constituting inverters is evident in this DOI; but total duplication of power switches is a major drawback. State of the art coupled 3-L DOIs reduce this drawback by providing series-shared...
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Enhancing Resilience of FSO Networks to Adverse Weather Conditions
PublikacjaOptical wireless networks realized by means of gigabit optical wireless communication (OWC) systems are becoming, in a variety of applications, an important alternative, or a complementary solution, to their fiber-based counterparts. However, performance of the OWC systems can be considerably degraded in periods of unfavorable weather conditions, such as heavy fog, which temporarily reduce the effective capacity of the network....
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Optimization of Wireless Networks for Resilience to Adverse Weather Conditions
PublikacjaIn this chapter, we consider how adverse weather conditions such as rain or fog affect the performance of wireless networks, and how to optimize these networks so as to make them robust to these conditions. We first show how to analyze the weather conditions in order to make them useful for network optimization modelling. Using an example realistic network, we show how to optimize two types of wireless networks: free-space optical...
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Control of Sensorless Electric Drive with Inverter Output Filter
PublikacjaW artykule przedstawiono układ sterowanie silnikiem asynchronicznym pracyjący bez pomiaru prędkości obrotowej. Zastosowano nowy rodzaj obserwatora prędkości obrotowej będący połączeniem liniowego obserwatora oraz obserwatora zakłóceń. Jako zakłócenia potraktowano siłę elektromotoryczną indukowaną w silniku. Aby umożliwić poprawną pracę układu z filtrem wyjściowym falownika zastosowano symulator dynamiki filtru do wyznaczenia prądów...
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Inverse Nonlinear Eigenvalue Problem Framework for the Synthesis of Coupled-Resonator Filters With Nonresonant Nodes and Arbitrary Frequency-Variant Reactive Couplings
PublikacjaA novel, general circuit-level description of coupledresonator microwave filters is introduced in this article. Unlike well-established coupling-matrix models based on frequency-invariant couplings or linear frequency-variant couplings (LFVCs), a model with arbitrary reactive frequencyvariant coupling (AFVC) networks is proposed. The engineered formulation is more general than prior-art ones—with the only restriction that the coupling...
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Antagonist activation exercises elicit similar post-activation performance enhancement as agonist activities on throwing performance
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In Vivo, In Vitro and In Silico Studies of the Hybrid Compound AA3266, an Opioid Agonist/NK1R Antagonist with Selective Cytotoxicity
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Phase 3 randomised study of avatrombopag, a novel thrombopoietin receptor agonist for the treatment of chronic immune thrombocytopenia
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Over-Voltage Studies in Inverter Fed Induction Motor Drives
PublikacjaW pracy przedstawiono metodę identyfikacji pojemności pasożytniczych uzwojeń silników asynchronicznych uwzględniającą ich rozłożony charakter. Przedstawiony szerokopasmowy model obwodowy uzwojeń silnika asynchronicznego pozwala na modelowanie zjawisk przepięciowych w silnikach asynchronicznych, w szczególności zasilanych poprzez przekształtniki energoelektroniczne. Zaproponowana metoda analizy umożliwia również określanie składowych...
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Asynchronous motor nonlinear control with inverter output LC filter
PublikacjaFiltr wyjściowy falownika jest stosowany w napędach elektrycznych prądu przemiennego o regulowanej prędkości w celu wygładzenia przebiegów prądów i napięć zasilających silnik. Zastosowanie filtru utrudnia realizację precyzyjnych metod sterowania silnikami, szczególnie w przypadku napędów bezczujnikowych (tj. bez czujnika prędkości obrotowej wału silnika). Ponieważ, ze względów praktycznych, nie stosuje się pomiarów prądów i napięć...
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Destructive Consequences of PWM Inverter Feeding for Traction AC Motors
PublikacjaThe electric traction drives with an AC motor fed by a frequency converter are used more and more often nowadays. The most significant side effects, of a converter's output voltage forming PWM method for AC motor windings, are steep voltage changes, which can initiate several destructive phenomena. The paper presents the adverse influence of a converter common mode voltage on the motor windings' increased voltage exposure and the...
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Hybrid Algorithm to Protect Java’s Code from Reverse Engineering
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Formulating a defensive technique to prevent the threat of prohibited reverse engineering
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Neural Graph Collaborative Filtering: Analysis of Possibilities on Diverse Datasets
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A strategy towards the generation of testable adverse outcome pathways for nanomaterials
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Selective Harmonic Elimination PWM For a Cascaded Multi-level Inverter
PublikacjaThis paper deals with the selective harmonic elimination pulse width modulation (SHE-PWM) technique. This technique is used for the elimination of selected dominant low order harmonics in the multi-level inverter output voltage. The presence of these harmonics is the essential drawback of such kind of inverters; especially when it is used for the control of different AC drivers. The SHE-PWM is based...
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Heat calculations for water-cooled radiators of the inverter for induction heating
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Solutions of inverter systems in Shore-to-Ship Power supply systems
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Five-Phase EV Drive with Switched-Autotransformer (LCCAt) Inverter
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Laparoscopic cholecystectomy in a patient with total situs inversus – case report
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Accurate modeling of quasi-resonant inverter fed IM drive
PublikacjaIn this paper wide-band modeling methodology of a parallel quasi-resonant dc link inverter (PQRDCLI) fed induction machine (IM) is presented. The modeling objective is early-design stage prediction of conductive electromagnetic interference (EMI) emissions of the considered converter fed IM drive system. Operation principles of the selected topology of PQRDCLI feeding IM drive are given. Modeling of the converter drive system is...