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Structural factors affecting affinity of cytotoxic oxathiole-fused chalcones toward tubulin
PublikacjaSynthesis, in vitro cytotoxic activity, and interaction with tubulin of (E)-1-(6-alkoxybenzo[d][1,3]oxathiol- 5-yl)-3-phenylprop-2-en-1-one derivatives (2) are described. Some of the compounds demonstrated cytotoxic activity at submicromolar concentrations, and the activity could be related to interaction with tubulin at the colchicine binding site. Interaction of selected derivatives with tubulinwas evaluated using molecular modeling,...
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Accurate rolling resistance Rolling resistance measurements can be influenced by a number of factors
PublikacjaTire rolling resistance is one of the most difficult-to-measure parameters of the tire/ pavement interface, especially if road measurements are required. First of all, it is necessary to measure a fairly small force in the system that is heavily loaded by other forces and subjected to many adverse effects causing measurement errors. The second problem is related to the fact that tire rolling resistance depends on many factors,...
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Sugar matters: sugar moieties as reactivity-tuning factors in quercetin O-glycosides
PublikacjaQuercetin, one of the most abundant flavonoids in plant-based foods, commonly occurs in nature in various glycosylated forms. There is still a less explored aspect regarding the cause of its glycosides diversity, depending on the sugars moiety attached. This work focuses on four widespread quercetin glycosides—hyperoside, isoquercitrin, quercitrin and rutin—by testing property-tuning capacity of different sugar moieties and thus...
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Preliminary Identification of Quantitative Factors Determining the Duration of Court Proceedings in Commercial Cases
PublikacjaPurpose: The aim of the article was to identify factors that are linear combinations of the variables under scrutiny that affect the duration of court proceedings. Design/Methodology/Approach: This research was conducted on commercial cases, based on the Principal Components Analysis (PCA). The original variables were grouped into factors that are correlated with each other. The Kaiser Criterion (own value >1) was chosen as the...
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Shading, Dusting and Incorrect Positioning of Photovoltaic Modules as Important Factors in Performance Reduction
PublikacjaThe amount of solar radiation reaching the front cover of a photovoltaic module is crucial for its performance. A number of factors must be taken into account at the design stage of the solar installation, which will ensure maximum utilization of the potential arising from the location. During the operation of a photovoltaic installation, it is necessary to limit the shading of the modules caused by both dust and shadowing by trees...
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Measurement of Unwanted Thought Suppression Strategies with the Thought Control Questionnaire in the General Polish Population: A Confirmatory Factor Analysis and Validation
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Genetic and biochemical determinants of serum concentrations of monocyte chemoattractant protein-1, a potential neural tube defect risk factor
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Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells
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Does Porcine Oocytes Maturation in Vitro is Regulated by Genes Involved in Transforming Growth Factor Beta Receptor Signaling Pathway?
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Expression of Osteoblast-Specific Factor 2 (OSF-2, Periostin) Is Associated with Drug Resistance in Ovarian Cancer Cell Lines
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Artificial Intelligence-Based Weighting Factor Autotuning for Model Predictive Control of Grid-Tied Packed U-Cell Inverter
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Result of the 6-min walk test is an independent prognostic factor of surgically treated non-small-cell lung cancer
PublikacjaPathological tumour, node and metastasis (TNM) stage remains the most significant prognostic factor of non-small-cell lung cancer (NSCLC). Meanwhile, age, gender, pulmonary function tests, the extent of surgical resection and the presence of concomitant diseases are commonly used to complete the prognostic profile of the patient with early stage of NSCLC. The aim of this study is to assess how the result of a 6-min walk test (6MWT)...
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Development of a Peptide Derived from Platelet-Derived Growth Factor (PDGF-BB) into a Potential Drug Candidate for the Treatment of Wounds
PublikacjaObjective: This study evaluated the use of novel peptides derived from platelet-derived growth factor (PDGF-BB) as potential wound healing stimulants. One of the compounds (named PDGF2) was subjected for further research after cytotoxicity and proliferation assays on human skin cells. Further investigation included evaluation of: migration and chemotaxis of skin cells, immunological and allergic safety, the transcriptional analyses...
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A study on the protection of methionine and the reduction of methionine sulfoxide in methionine-containing analogues of the growth-modeling factor Gly-His-Lys
PublikacjaThe protection of methionine and the reduction of methionine sulfoxide in methionine-containing analogues of Gly-His-Lys are described. The peptides were synthesized by a solid-phase method using the standard Fmoc procedure. Simultaneous deprotection of the peptide side chain and liberation from the resin were achieved using an appropriate TFA cocktail. The TFA cocktail was selected to minimize oxidation of the methionine residue....
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The evaluation of COD fractionation and modeling as a key factor for appropriate optimization and monitoring of modern cost-effective activated sludge systems
PublikacjaA study was conducted to characterize the raw wastewater entering a modern cost effective municipal WWTP in Poland using two approaches; 1) a combination of modeling and carbonaceous oxygen demand (COD) fractionation using respirometric test coupled with model estimation (RTME) and 2) flocculation/filtration COD fractionation method combined with BOD measurements (FF-BOD). It was observed that the particulate fractions of COD obtained...
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Structure-function analysis of decay-accelerating factor: identification ofresidues important for binding of the Escherichia coli Dr adhesin and complement regulation
PublikacjaZidentyfikowano ważne dla wiązania adhezyny Dr uropatogennych Escherichiacoli reszty aminokwasowe w ludzkim receptorze DAF SCR-3.
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Diagnostic Analysis of Exhaust Gas with A Quick-Changing Temperature from a Marine Diesel Engine Part II / Two Factor Analysis
PublikacjaThe article presents a continuation of research carried out to determine the effect of input parameters (changes in engine structure parameters) on selected output parameters (diagnostic measures), based on quickly changing exhaust gas temperature. A method of determining the simultaneous influence of two input factors (the structure parameter and the engine load) on one output factor was presented, as well as an evaluation...
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The serum concentration of brain-derived neurotrophic factor is lower in ambulatory and clinically stable patients with more advanced systolic heart failure
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Influence of narrowband ultraviolet B phototherapy on serum tumour necrosis factor-like weak inducer of apoptosis (TWEAK) in patients with psoriasis
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Design, synthesis and in vitro biological evaluation of a small cyclic peptide as inhibitor of vascular endothelial growth factor binding to neuropilin-1
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Branched pentapeptides as potent inhibitors of the vascular endothelial growth factor 165 binding to Neuropilin-1: Design, synthesis and biological activity
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The Role of Hypoxia-Inducible Factor-1α, Glucose Transporter-1, (GLUT-1) and Carbon Anhydrase IX in Endometrial Cancer Patients
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Vascular endothelial growth factor (VEGF-C1)-dependent inflammatory response of podocytes in nephrotic syndrome glomerulopathies in children: an immunohistochemical approach
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Emissions of selected monoaromatic hydrocarbons as a factor affecting the removal of single-use polymer barbecue and kitchen utensils from everyday use
PublikacjaThe main focus of this study is the emission of monoaromatic hydrocarbons because these are the preliminary factors of potential solvent and monomer residues present in single-use plastic barbecue and kitchen utensils comprising polystyrene, polypropylene, natural cellulose, and biodegradable polymers intended for use with hot meal or beverages. Herein, the emissions of monoaromatic hydrocarbons (styrene, benzene, toluene, ethylbenzene,...
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The advanced monitoring as a key factor for appropriate optimization and control of full-scale activated sludge systems – case study Debogorze WWTP.
PublikacjaComputer simulation has become a helpful tool in wastewater treatment systems performance and effectiveness analysis. Advanced monitoring, by using appropriate software, enables to create a mathematical model of a real wastewater treatment plant (WWTP), run a simulation and subsequently interpret results under various conditions. An operation of WWTP is usually controlled by global parameters such as flow, solids retention time,...
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Influence of sensor design and optical properties of tissue on the photoplethysmographic signal
PublikacjaPhotopletysmography and an associated technique called pulse oximetry are still explored due to the expectations that they give a lot of information about the state of the patient and, also, due to the fact that they are non invasive. Knowledge about the impact of various parameters on the measured signal leads to a faster and a more reliable way of analyzing measurement results and finding the dependencies between the involved...
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Manufacturing collective intelligence by the means of Decisional DNA and virtual engineering objects, process and factory
PublikacjaEngineering collective intelligence is paramount in current industrial times. This research proposes and presents case studies for collective knowledge structures required in the industry field. Knowledge structures such as Set of Experience and Decisional DNA are extended into more advanced knowledge structures for manufacturing processes. These structures are called Virtual Engineering Object, Virtual Engineering Process and...
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Factory Acceptance Test – Strain Gauge Measurement, Report no: WOiO /II/123/2014
PublikacjaTested object was 40 meters long jib and its foundation, placed in Gdansk Shiprepair Yard, manufactured by KMK. The contruction was dedicated to the passenger cruise vessel "Quantum of the Seas" The Strain Gauge measurement in different location and load situation was done in order to validate calculation finite element models used during strength analysis for project. The expertise contains: methodology of the measurements, description...
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Factory Acceptance Test – Strain Gauge Measurement - Report no: WOiO /II/88/2014
PublikacjaTested object was 40 meters long jib and its foundation, placed in Gdansk Shiprepair Yard, manufactured by KMK. The contruction was dedicated to the passenger cruise vessel "North Star" The Strain Gauge measurement in different location and load situation was done in order to validate calculation finite element models used during strength analysis for project. The expertise contains: methodology of the measurements, description...
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A methodology for incorporating human factors in fuzzy-probabilistic modelling and risk analysis of industrial systems
PublikacjaPraca dotyczy wybranych zagadnień rozmyto-probabilistycznych modelowania złożonych systemów przemysłowych. Do obliczeń związanych z analizą ryzyka stosuje się diagramy wpływu i hierarchiczny proces decyzyjny.
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Laboratory Bioassay of Selected Entomopathogenic Nematodes as Mortality Factors of Oulema melanopus (Coleoptera: Chrysomelidae)
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Influence of Selected Factors on the Survival Assessment and Detection of Giardia intestinalis DNA in Axenic Culture
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Indigenous Perceptions of Factors Influencing Behavioral Intentions Towards Climate Change Mitigation: An Assessment
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Suicidal thoughts in persons treated for alcohol dependence: The role of selected demographic and clinical factors
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Analysis of Emission Factors in RDE Tests As Well as in NEDC and WLTC Chassis Dynamometer Tests
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Effects of stressful physico-chemical factors on the fitness of the plant pathogenic bacterium Dickeya solani
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Determination of collision criteria and causation factors appropriate to a model for estimating the probability of maritime accidents
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Enhancing human performance in ship operations by modifying global design factors at the design stage
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Civil Projects (Participatory), Company Funds and Small Grants as Factors Integrating Local Communities
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TGF-β gene polimorphisms as risk factors for asthma control among clinic patients
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TGF-β gene polimorphisms as risk factors for asthma control among clinic patients.
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TGF-β gene polimorphisms as risk factors for asthma control among clinic patients.
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Environmental Factors and the Risk of Developing Type 1 Diabetes—Old Disease and New Data
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Biodegradable polymers for food packaging - factors influencing their degradation and certification types - a comprehensive review
PublikacjaIn the paper an overview of novel biodegradable polymers for food packaging can be found. The aim was to present factors influencing polymer degradation and biodegradation in various environments. It was noted that biodegradable polymers are imperfect alternative for classical polymers and its decomposition strongly depends on degradation environment.
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Managing safety of industrial hazardous installations with emphasis on the control systems, interfaces and human factors
PublikacjaIn the paper a procedure for the layer of protection analysis (LOPA) as a tool to evaluate the risk of accident scenarios occurrence in hazardous installations is outlined. In such installations several protection layers exist. Human operator performance in each layer is unavoidable, but the role and tasks are different and depend on the context of situation. Based on suggestions form literature (EEMUA, CREAM) and own proposals...
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Exchange of radiation in high temperature air combustion furnaces by application of the transfer configuration factors
PublikacjaW artykule przedstawiono metodę obliczeń pasmowej radiacyjnej wymiany ciepła w układzie otwartym z gazem iztermicznym za pomocą uogólnionych współczynników konfiguracji. Metoda może być użyta do obliczeń wymiany ciepła w piecach z technologią High Temperature Air Combustion gdzie występuje prawie jednorodna temperatura. Podano przykład obliczeniowy.
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Evaluation of occupational exposure in a slide bearings factory on the basis of urine and blood sample analyses
PublikacjaZbadano wpływ pracy w zakładach łożysk ślizgowych na zdrowie pracowników. Przeprowadzono analizę próbek moczu i krwi pobranych od 42 pracowników i 6 osób zatrudnionych w administracji przedsiębiorstwa, stanowiących grupę kontrolną. Oznaczono zawartość Al, Cu, Pb i Zn we krwi i moczu pracowników dwukrotnie, przed i po terapii za pomocą chelatowania, stosując ICP-MS oraz metodę dodatku wzorca. Istotność różnic w zawartości pierwiastków...
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Relationships between Selected Physiological Factors and Milking Parameters for Cows Using a Milking Robot
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Editorial: Citizen Science and Social Innovation: Mutual Relations, Barriers, Needs, and Development Factors
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IDENTIFICATION AND COMPARATIVE ANALYSIS OF FACTORS INFLUENCING ROAD SAFETY IN US REGIONS AND IN POLISH VOIVODESHIPS
PublikacjaAnalyses of road safety at national level have been run for many years and large number of publications concerning them appeared so far. How interdisciplinary the issue is, has been shown by literature studies done by the author of the paper. It appears that economists, mathematicians, doctors as well as engineers have studied the issue. It is not an easy one, as results of many analyses lead to conflicting conclusions and...