Wyszukiwarka
Filtry
wszystkich: 820
wybranych: 779
Wyniki wyszukiwania dla: OXIDATIVE CYCLIZATION
-
Transition-Metal-Promoted Oxidative Cyclization To Give 1,2,4-Trisubstituted Carbazole Scaffolds
PublikacjaHerein, we describe the synthesis of a 1,2,4-trisubstituted carbazole core from 5-(1H-indol-3-yl)-3-oxopentanoic acid esters or amides. For oxidative cyclization, we tested two different approaches. First, we used manganese triacetate as a conventional moderate oxidizer to ensure the radical course of the reaction. Second, we examined the use of a more complex oxidizing agent I2/Me(OTf)3. In both cases, formation of a fused-ring...
-
Oxidatively Damaged DNA/Oxidative Stress in Children with Celiac Disease
Publikacja -
Effect of head-to-tail cyclization on conformation of histatin-5
Publikacja -
Effect of Disulfide Cyclization of Ultrashort Cationic Lipopeptides on Antimicrobial Activity and Cytotoxicity
Publikacja -
Simple and novel synthesis of 3-(thio)phosphoryl-β-lactams by radical cyclization
PublikacjaRadical cyclization of phosphono-acetenamides promoted by manganese(III) acetate leads exclusively to the formation of 3-phosphoryl-β-lactams. The thiophosphoryl analogues were also prepared using this method. In particular, the presented protocol does not require the use of noble metals, while comparable methods do.
-
Convenient synthesis of 3-phosphono-β-lactams through the cyclization ofN-alkenyl-phosphonoacetamides
PublikacjaOxidative cyclization through the treatment by the transition metals is convenientsynthetic tool with a great number of applications. In the most cases the result is the formationof C-C bond between generated radical and unsaturated part of the same or another molecule.As it was presented by Trogolo it is also suitable way to obtain 4-membered heterocyclicβ-lactamic ring[1]. In this communicate we want to present new application...
-
Small field radiotherapy of head and neck cancer patients is responsible for oxidatively damaged DNA/oxidative stress on the level of a whole organism
Publikacja -
Synthesis of 3-Carbamoyl b-Lactams via Manganese(III)-Promoted Cyclization of N-Alkenylmalonamides
PublikacjaManganese(III)-promoted cyclization of N-alkenylmalonamides (¼N-alkenylpropanediamides) gave 3-(aryl/(alkylamino)carbonyl) b-lactams as well as 3-(aryl/(alkylamino)thiocarbonyl) b-lactams. The relative configuration of the obtained products was unambiguously determined by X-ray crystallography. The proposed method is very useful for the one-pot synthesis of a number of 3-(aryl/ (alkylamino)carbonyl) b-lactams, especially those...
-
Treatment of bitumen post oxidative effluents by sulfate radicals based advanced oxidation processes (S-AOPs) under alkaline pH conditions
PublikacjaSulfate radicals based Advanced Oxidation Processes (S-AOPs), namely Persulfate and peroxymonosulfate, were used for the treatment of post oxidative effluents from a production of petroleum bitumens under alkaline pH. Studies on the identification and monitoring of the volatile organic compounds (VOCs) along with COD, BOD and sulfide ions reduction were performed. Persulfate with a ratio between the oxygen from the oxidant and...
-
Oxidative stress and oxidative DNA damage is characteristic for mixed Alzheimer disease/vascular dementia
Publikacja -
Functionalization of Graphite with Oxidative Plasma
Publikacja -
The Influence of Oxidative Stress on Thyroid Diseases
Publikacja -
Manganese(III) Promoted Cyclization of N-alkenyl-N-(2-hydroxyethyl) amides to Iso-Oxacepham Potent β-Lactamase Inhibitors
PublikacjaBackground: β-Lactams are still a subject of interest of organic chemists. The main reason for this interest is due to their application as a chemotherapeutic. β-Lactam antibiotics are still the most commonly used drugs in bacterial infections. Method: Methods using 4-exo-trig radical cyclization leading to β-lactams are an alternative to classical Staudinger`s β-Lactams formation. We prepared N-alkenyl-N-(2-hydroxyethyl)amides...
-
Persistent oxidative stress in colorectal carcinoma patients
Publikacja -
Oxidative Stress as an Important Contributor to the Pathogenesis of Psoriasis
Publikacja -
Comparison of oxidative stability of different edible oils
PublikacjaCelem prezentowanych badań było porównanie stabilności oksydacyjnej olejów roślinnych z Polski, Finlandii i Hiszpanii. Na etapie przyspieszania utleniania zastosowano promieniowanie ultrafioletowe (UV). Po naświetlaniu olejów powstałe związki lotne ekstrahowano z fazy nadpowierzchniowej za pomocą techniki mikroekstrakcji do fazy stacjonarnej (HS-SPME) i analizowano z zastosowaniem chromatografu gazowego z detektorem płomieniowo-jonizacyjnym...
-
Estimation of Oxidative Stress Markers in Chronic Kidney Disease
Publikacja -
Oxidative stress in humans: validation of biomarkers of DNA damage
Publikacja -
Cylindrospermopsin decreases the oxidative burst capacity of human neutrophils
Publikacja -
The Therapeutic Potential of Cannabis in Counteracting Oxidative Stress and Inflammation
Publikacja -
The Influence of Circadian Rhythm on the Activity of Oxidative Stress Enzymes
Publikacja -
Oxidative stress as a hidden cost of attractiveness in postmenopausal women
Publikacja -
Propargylamines in Pd/Cu-catalyzed tandem coupling-cyclization-N-deprotection in a single pot: Construction of N-unsubstituted vs N-sulfonyl indole ring
Publikacja -
Oxidative Modification of Proteins in Pediatric Cystic Fibrosis with Bacterial Infections
Publikacja -
Dynamics of Oxidative Damage at Early Stages of Estrogen-dependant Carcinogenesis
Publikacja -
Effects of basal level of antioxidants on oxidative DNA damage in humans
Publikacja -
Does morphology of carotid plaque depend on patient's oxidative stress?
Publikacja -
Influence of cabbage juices on oxidative changes of rapeseed oil and lard
PublikacjaCelem badań było określenie wpływu soków wyizolowanych z kapusty surowej i kiszonej na przemiany oksydatywne i termooksydatywne tłuszczów roślinnych (na przykładzie oleju rzepakowego podwójnie ulepszonego) i zwierzęcych (na przykładzie smalcu). Tłuszcze te ogrzewano w temperaturze 100 0C z sokami z kapusty w układzie modelowym przez 6 godzin, pobierając co 1,5 godz. próbki do badań.Po procesie ogrzewania tłuszczów w obecnosci soków...
-
Chromatographic Examinations of Tea's Protection Against Lipid Oxidative Modifications
Publikacja -
Sex differences in oxidative stress after eccentric and concentric exercise
Publikacja -
Elucidating of oxidative distress in COVID-19 and methods of its prevention
Publikacja -
Oxidative DNA Damage in Blood of CVD Patients Taking Detralex
Publikacja -
Oxidative Stress as a Possible Target in the Treatment of Toxoplasmosis: Perspectives and Ambiguities
Publikacja -
Association of Genes Related to Oxidative Stress with the Extent of Coronary Atherosclerosis
PublikacjaOxidative stress is believed to play a critical role in atherosclerosis initiation and progression. In line with this, in a group of 1099 subjects, we determined eight single nucleotide polymorphisms (SNPs) related to oxidative stress (PON1 c.575A>G, MPO c.463G>A, SOD2 c.47T>C, GCLM c.590C>T, NOS3 c.894G>T, NOS3 c.786T>C, CYBA c.214C>T, and CYBA c.932A>G) and assessed the extent of atherosclerosis in coronary arteries based on...
-
EFFECT OF ANTIOXIDANTS ON THE STABILITY OF PITCH- BASED POLYMER TO THERMO-OXIDATIVE ACTION
PublikacjaThe influence of stabilizers – hydrogen donors – on the processes of thermooxidative destruction of pitch-based polymer has been investigated. It is shown that Irganox has not stabilizing effect on pitch-based polymer and melamine slightly retards the destructive process. A mixture of melamine and Irganox exhibits synergetic stabilizing effect and at the optimum ratio it can be used to prevent unwanted thermooxidative processes...
-
Protective effect of desloratadine against oxidative stress in human erythrocytes in vitro
Publikacja -
High Concentrations of Excised Oxidative DNA Lesions in Human Cerebrospinal Fluid
Publikacja -
Oxidative DNA damage in cancer patients: a cause or a consequence of the disease development?
Publikacja -
Oxidative Stress Level in the Testes of Mice and Rats during Nickel Intoxication
Publikacja -
Seed-Roasting Process Affects Oxidative Stability of Cold-Pressed Oils
Publikacja -
Isoprostanes-Biomarkers of Lipid Peroxidation: Their Utility in Evaluating Oxidative Stress and Analysis
PublikacjaIsoprostanes (IsoPs) are key biomarkers for investigating the role of free radical generation in the pathogenesis of human disorders. To solve IsoPs-related problems with regard to isoprostanes, analytical tools are required. This paper reviews the problems and trends in this field focusing on the methodology for assaying biomarkers in exhaled breath condensate (EBC) samples. A large amount of work has been done in the qualitative...
-
Sweet grass protection against oxidative stress formation in the rat brain
Publikacja -
Air Pollution, Oxidative Stress, and the Risk of Development of Type 1 Diabetes
Publikacja -
The Influence of Winter Swimming on Oxidative Stress Indicators in the Blood of Healthy Males
Publikacja -
Selenium Supplementation Reduced Oxidative DNA Damage in Adnexectomized BRCA1 Mutations Carriers
Publikacja -
Further evidence that oxidative stress may be a risk factor responsible for the development of atherosclerosis
Publikacja -
Oxidative stress and 8-oxoguanine repair are enhanced in colon adenoma and carcinoma patients
Publikacja -
Comparison of Oxidative Stress/DNA Damage in Semen and Blood of Fertile and Infertile Men
Publikacja -
Conidiobolus coronatus induces oxidative stress and autophagy response in Galleria mellonella larvae
Publikacja -
Effect of sweet grass extract against oxidative stress in rat liver and serum
Publikacja